SCI时时刷

search
Sulforaphane upregulates the mRNA expression of NRF2 and NQO1 in non-dialysis patients with chronic kidney disease
Sulforaphane upregulates the mRNA expression of NRF2 and NQO1 in non-dialysis patients with chronic kidney disease
Patients with chronic kidney disease (CKD) have a pro-oxidant state marked by reduced enzymatic antioxidant defense. Oxida...
E3 ubiquitin ligase RBCK1 confers ferroptosis resistance in pancreatic cancer by facilitating MFN2 degradation
E3 ubiquitin ligase RBCK1 confers ferroptosis resistance in pancreatic cancer by facilitating MFN2 degradation
Pancreatic ductal adenocarcinoma (PDAC) is one of the most intractable malignancies, accounting for nearly eight percent o...
TRPV3 facilitates lipolysis and attenuates diet-induced obesity via activation of the NRF2/FSP1 signaling axis
TRPV3 facilitates lipolysis and attenuates diet-induced obesity via activation of the NRF2/FSP1 signaling axis
Over the past four decades, the prevalence of obesity has continued to escalate at an alarming rate [1,2]. Over half of th...
Photodynamic treatment increases the lifespan and oxidative stress resistance of Caenorhabditis elegans
Photodynamic treatment increases the lifespan and oxidative stress resistance of Caenorhabditis elegans
Volume 221, 20 August 2024, Pages 98-110Author links open overlay panel, , , , , , , , , Highlights•A Photodynamic reactio...
MCU inhibition protects against intestinal ischemia‒reperfusion by inhibiting Drp1-dependent mitochondrial fission
MCU inhibition protects against intestinal ischemia‒reperfusion by inhibiting Drp1-dependent mitochondrial fission
Intestinal ischemia‒reperfusion (IIR) injury is a common complication of surgery, but clear molecular insights and valuabl...
Deciphering the enigma of the function of alpha-tocopherol as a vitamin
Deciphering the enigma of the function of alpha-tocopherol as a vitamin
This article is a summary of the talk I gave during the opening session of the 2023 SfRBM/SFRRI at the presentation of the...
TIPE1 limits virus replication by disrupting PKM2/ HIF-1α/ glycolysis feedback loop
TIPE1 limits virus replication by disrupting PKM2/ HIF-1α/ glycolysis feedback loop
Volume 221, 20 August 2024, Pages 52-63Author links open overlay panel, , , , , , , , , , Highlights•TIPE1 restricts viral...
Attenuation of DNA base oxidation in post-surgery colorectal stage III patients at subsequent follow-ups
Attenuation of DNA base oxidation in post-surgery colorectal stage III patients at subsequent follow-ups
Volume 221, 20 August 2024, Pages 75-80Author links open overlay panel, , , , , , , , , , Highlights•Elevated DNA base oxi...
Lactate regulates respiratory efficiency and mitochondrial dynamics in primary rat podocytes
Lactate regulates respiratory efficiency and mitochondrial dynamics in primary rat podocytes
Podocytes are crucial for regulating glomerular permeability. They have foot processes that are integral to the renal filt...
Maternal selenium deficiency during pregnancy in association with autism and ADHD traits in children: The Odense Child Cohort
Maternal selenium deficiency during pregnancy in association with autism and ADHD traits in children: The Odense Child Cohort
Volume 220, 1 August 2024, Pages 324-332Author links open overlay panel, , , , , , , , , Highlights•Analysis of maternal S...
Upregulation of GPX4 drives ferroptosis resistance in scleroderma skin fibroblasts
Upregulation of GPX4 drives ferroptosis resistance in scleroderma skin fibroblasts
Systemic sclerosis (SSC) is a chronic autoimmune-triggered disease [1], and skin fibrosis is a prominent feature that lead...
Roquin-2 promotes oxidative stress-induced cell death by ubiquitination-dependent degradation of TAK1
Roquin-2 promotes oxidative stress-induced cell death by ubiquitination-dependent degradation of TAK1
Reactive oxygen species (ROS) are highly reactive and their accumulation causes oxidative damage to cells. Cells maintain ...
Metallofullerenol alleviates alcoholic liver damage via ROS clearance under static magnetic and electric fields
Metallofullerenol alleviates alcoholic liver damage via ROS clearance under static magnetic and electric fields
Alcoholic liver disease (ALD) is the most prevalent chronic liver disease worldwide [1]. Alcohol consumption has been stea...
ALKBH5 targets ACSL4 mRNA stability to modulate ferroptosis in hyperbilirubinemia-induced brain damage
ALKBH5 targets ACSL4 mRNA stability to modulate ferroptosis in hyperbilirubinemia-induced brain damage
Hyperbilirubinemia, one of the most common clinical neonatal diseases, is characterized by the accumulation of bilirubin (...
Interplay between hypoxia inducible Factor-1 and mitochondria in cardiac diseases
Interplay between hypoxia inducible Factor-1 and mitochondria in cardiac diseases
Ischemic heart diseases and cardiomyopathies are characterized by hypoxia, energy starvation and mitochondrial dysfunction...
Isoliquiritigenin alleviates myocardial ischemia-reperfusion injury by regulating the Nrf2/HO-1/SLC7a11/GPX4 axis in mice
Isoliquiritigenin alleviates myocardial ischemia-reperfusion injury by regulating the Nrf2/HO-1/SLC7a11/GPX4 axis in mice
Nowadays, the incidence of acute myocardial infarction (AMI) remains a significant contributor to global mortality rates. ...
MitoTempo protects against nε-carboxymethyl lysine-induced mitochondrial dyshomeostasis and neuronal cells injury
MitoTempo protects against nε-carboxymethyl lysine-induced mitochondrial dyshomeostasis and neuronal cells injury
Enhanced formation of advanced glycation end products (AGEs) is a pivotal factor in diabetes pathophysiology, increasing t...
Elevated levels of iodide promote peroxidase-mediated protein iodination and inhibit protein chlorination
Elevated levels of iodide promote peroxidase-mediated protein iodination and inhibit protein chlorination
At inflammatory sites, immune cells generate oxidants including H₂O₂. Myeloperoxidase (MPO), released by activated leukocy...
PARP1 inhibition prevents oxidative stress in age-related hearing loss via PAR-Ca2+-AIF axis in cochlear strial marginal cells
PARP1 inhibition prevents oxidative stress in age-related hearing loss via PAR-Ca2+-AIF axis in cochlear strial marginal cells
Oxidative stress, which damages the inner ear, is an important cause of several types of sensorineural hearing loss, inclu...
Dopamine and its precursor levodopa inactivate SARS-CoV-2 main protease by forming a quinoprotein
Dopamine and its precursor levodopa inactivate SARS-CoV-2 main protease by forming a quinoprotein
The COVID-19 pandemic trigged by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a catastrophic impac...
What can reactive oxygen species (ROS) tell us about the action mechanism of herbicides and other phytotoxins?
What can reactive oxygen species (ROS) tell us about the action mechanism of herbicides and other phytotoxins?
Elimination of weeds is of critical importance for full realization of the yield potential of crops in anthropogenic ecosy...