SCI时时刷

search
+
FEV-mediated WNT2 transcription is involved in the progression of colorectal cancer via the Wnt signaling
FEV-mediated WNT2 transcription is involved in the progression of colorectal cancer via the Wnt signaling
Colorectal cancer (CRC) remains the third leading cause of cancer-related death worldwide. Here, we aimed to uncover the m...
Development of scaffold-free tissue-engineered constructs derived from mesenchymal stem cells with serum-free media for cartilage repair and long-term preservation
Development of scaffold-free tissue-engineered constructs derived from mesenchymal stem cells with serum-free media for cartilage repair and long-term preservation
Synovial mesenchymal stem cells (sMSCs) have great potential for cartilage repair, but their therapeutic design to avoid a...
KLF7 reverses ox-LDL-induced ferroptosis in HMEC-1 cells through transcriptionally activating ALKBH5 to inhibit the m6A modification of ACSL4
KLF7 reverses ox-LDL-induced ferroptosis in HMEC-1 cells through transcriptionally activating ALKBH5 to inhibit the m6A modification of ACSL4
Atherosclerosis is a chronic inflammatory vascular disease. It was confirmed that activation of ferroptosis could induce t...
KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation
KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation
KIAA1429 has been reported as a cancer regulator, but its role and mechanism in the progression of oral squamous cell carc...
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim
Colorectal cancer (CRC) is a common tumor type, and liver metastasis reduces the long-term survival in CRC patients. Natur...
Correction: LncRNA-NNT-AS1 contributes to the progression of glioma by miR-582-5p/EZH2 axis
Correction: LncRNA-NNT-AS1 contributes to the progression of glioma by miR-582-5p/EZH2 axis
Knockdown of NNT-AS1 expression inhibits glioma progression via miR-582-5p/EZH2 axis. a The RT-qPCR assay was implemented ...
Formation of ovarian organoid by co-culture of human endometrial mesenchymal stem cells and mouse oocyte in 3-dimensional culture system
Formation of ovarian organoid by co-culture of human endometrial mesenchymal stem cells and mouse oocyte in 3-dimensional culture system
The purpose of this study was to compare the formation of organoid structures by co-culturing of human endometrial mesench...
Obtusifolin inhibits podocyte apoptosis by inactivating NF-κB signaling in acute kidney injury
Obtusifolin inhibits podocyte apoptosis by inactivating NF-κB signaling in acute kidney injury
Acute kidney injury (AKI) is a common clinical condition and is associated with unacceptable morbidity and mortality. Obtu...
Melatonin enhances therapeutic outcomes of adipose tissue-derived mesenchymal stem cell therapy in rat osteoarthritis by reducing TNF-α and IL-1β-induced injuries
Melatonin enhances therapeutic outcomes of adipose tissue-derived mesenchymal stem cell therapy in rat osteoarthritis by reducing TNF-α and IL-1β-induced injuries
Although adipose tissue-derived mesenchymal stem cell (ADSC) transplantation has been effectively used to treat osteoarthr...
Exosomes from myoblasts induced by hypoxic preconditioning improved ventricular conduction by increasing Cx43 expression in hypothermia ischemia reperfusion hearts
Exosomes from myoblasts induced by hypoxic preconditioning improved ventricular conduction by increasing Cx43 expression in hypothermia ischemia reperfusion hearts
Myocardial ischemia–reperfusion arrhythmia after cardiac surgery is common and seriously affects quality of life. Re...
Heparanase accelerates the angiogenesis and inhibits the ferroptosis of p53-mutant non-small cell cancers in VEGF-dependent manner
Heparanase accelerates the angiogenesis and inhibits the ferroptosis of p53-mutant non-small cell cancers in VEGF-dependent manner
The aim of this study is to explore the effects and specific mechanisms of heparanase on angiogenesis and iron deficiency ...
LncRNA RP11-818O24.3 promotes hair-follicle recovery via FGF2-PI3K/Akt signal pathway
LncRNA RP11-818O24.3 promotes hair-follicle recovery via FGF2-PI3K/Akt signal pathway
A previous study indicated that patients with androgenic alopecia (AGA) have significantly reduced levels of LncRNA RP11-8...
FGF21 relieves calcium oxalate-induced cell injury, apoptosis, oxidative damage and ferroptosis of renal tubular epithelial cells through activating Nrf2 signaling pathway
FGF21 relieves calcium oxalate-induced cell injury, apoptosis, oxidative damage and ferroptosis of renal tubular epithelial cells through activating Nrf2 signaling pathway
Nephrolithiasis is a common urological disease accompanied by high morbidity worldwide. Evidences indicate that high-level...
From stem cells to extracellular vesicles: a new horizon in tissue engineering and regenerative medicine
From stem cells to extracellular vesicles: a new horizon in tissue engineering and regenerative medicine
In the fields of tissue engineering and regenerative medicine, extracellular vesicles (EVs) have become viable therapeutic...
Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes
Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes
Cardiovascular diseases remain as the most common cause of death worldwide. To reveal the underlying mechanisms in varying...
miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN
miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN
Pulmonary arterial smooth muscle cells (PASMCs) functions are associated with the pathogenesis of pulmonary hypertension (...
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a centr...
PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway
PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway
Pancreatic cancer is difficult to manage owing to the challenges involved in its treatment and nursing. This study aimed t...
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
Fulminant hepatitis (FH) is a life-threatening clinical liver syndrome characterized by substantial hepatocyte necrosis an...
Stable two- and three-dimensional cholangiocyte culture systems from extrahepatic bile ducts of biliary atresia patients: use of structural and functional bile duct epithelium models for in vitro analyses
Stable two- and three-dimensional cholangiocyte culture systems from extrahepatic bile ducts of biliary atresia patients: use of structural and functional bile duct epithelium models for in vitro analyses
We herein report two- (2D) and three-dimensional (3D) culture methods of cholangiocytes originating from extrahepatic bile...
The effect of TFAP2A/ANXA8 axis on ferroptosis of cervical squamous cell carcinoma (CESC) in vitro
The effect of TFAP2A/ANXA8 axis on ferroptosis of cervical squamous cell carcinoma (CESC) in vitro
Potential role and associated mechanisms of Annexin A8 (ANXA8), a member of the Annexins family, in cervical squamous cell...
Degranulation of RBL-2H3 rat basophilic leukemia cells is synergistically inhibited by combined treatment with nobiletin and lactoferrin
Degranulation of RBL-2H3 rat basophilic leukemia cells is synergistically inhibited by combined treatment with nobiletin and lactoferrin
The aim of this study was to elucidate the anti-allergic effects of polymethoxyflavonoids in combination with milk protein...
LncRNA MIR181A2HG negatively regulates human keratinocytes proliferation by binding SRSF1
LncRNA MIR181A2HG negatively regulates human keratinocytes proliferation by binding SRSF1
Psoriasis is a common chronic inflammatory skin disease. Abnormal proliferation of keratinocytes plays an important role i...
Schizandrin A enhances the sensitivity of gastric cancer cells to 5-FU by promoting ferroptosis
Schizandrin A enhances the sensitivity of gastric cancer cells to 5-FU by promoting ferroptosis
Schizandrin A (Sch A) exert anticancer and multidrug resistance-reversing effects in a variety of tumors, but its effect o...
Anti-cancer drug-mediated increase in mitochondrial mass limits the application of metabolic viability-based MTT assay in cytotoxicity screening
Anti-cancer drug-mediated increase in mitochondrial mass limits the application of metabolic viability-based MTT assay in cytotoxicity screening
The high-throughput metabolic viability-based colorimetric MTT test is commonly employed to screen the cytotoxicity of dif...
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes
Immature mandarin orange is thinned in order to maturation of orange. To use immature mandarin orange as a cosmetic functi...
LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA
LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA
LncRNA HOTAIR has been reported to be associated with metabolic diseases of the liver. However, the effect of HOTAIR on no...
Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis
Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis
Corneocytes and intercellular lipids form the stratum corneum. The content and composition of intercellular lipids in the ...
Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells
Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells
Cirrhosis is a familiar end-stage of multiple chronic liver diseases. The gene-modified mesenchymal stem cells (MSCs) have...
miR-92a-3p promotes pulmonary fibrosis progression by regulating KLF2-mediated endothelial-to-mesenchymal transition
miR-92a-3p promotes pulmonary fibrosis progression by regulating KLF2-mediated endothelial-to-mesenchymal transition
Pulmonary fibrosis (PF) is a chronic lung disease that has a poor prognosis and a serious impact on the quality of life of...
阅读更多
format_indent_increase