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LncRNA NORAD sponging to miR-26b-5p represses the progression of Alzheimer’s disease in vitro by upregulating MME expression
LncRNA NORAD sponging to miR-26b-5p represses the progression of Alzheimer’s disease in vitro by upregulating MME expression
Alzheimer’s disease (AD) is a progressive neurological condition that causes brain shrinkage and cell death. This st...
Oral cell lysates reduce osteoclastogenesis in murine bone marrow cultures
Oral cell lysates reduce osteoclastogenesis in murine bone marrow cultures
Mechanical and thermal cell damage can occur due to invasive procedures related to drilling, the insertion of dental impla...
Evaluating the impact of media and feed combinations on CHO cell culture performance and monoclonal antibody (trastuzumab) production
Evaluating the impact of media and feed combinations on CHO cell culture performance and monoclonal antibody (trastuzumab) production
The choice of media and feeds significantly influences the performance of Chinese Hamster Ovary (CHO) mammalian cell cultu...
Anti-angiogenic and anti-oxidant effects of 2-NTI indole derivative vs. suramin in ex vivo, in vivo, and in vitro studies
Anti-angiogenic and anti-oxidant effects of 2-NTI indole derivative vs. suramin in ex vivo, in vivo, and in vitro studies
Angiogenesis is an intricate pathway that involves the formation of new blood capillaries from old, functioning ones. Impr...
Neurotrophomodulatory effect of TNF-α through NF-κB in rat cortical astrocytes
Neurotrophomodulatory effect of TNF-α through NF-κB in rat cortical astrocytes
Tumor necrosis factor alpha (TNF-α) is a well-known pro-inflammatory cytokine originally recognized for its ability t...
The protective role of baicalin regulation of autophagy in cancers
The protective role of baicalin regulation of autophagy in cancers
Autophagy is a conservative process of self degradation, in which abnormal organelles, proteins and other macromolecules a...
The regulatory role of KIAA1429 in epithelial-mesenchymal transition in cervical cancer via mediating m6A modification of BTG2
The regulatory role of KIAA1429 in epithelial-mesenchymal transition in cervical cancer via mediating m6A modification of BTG2
Cervical cancer (CC) represents one of the important cancers affecting global female population worldwide. We sought to el...
The study on bone marrow mesenchymal stem cell-derived extracellular matrix promoting the repair of damaged chondrocytes by regulating the Notch1/RBPJ pathway
The study on bone marrow mesenchymal stem cell-derived extracellular matrix promoting the repair of damaged chondrocytes by regulating the Notch1/RBPJ pathway
Cartilage and joint damage can lead to cartilage degeneration. Bone marrow mesenchymal stem cells (BMSCs) have the potenti...
Growth suppressing effect of Fagonia arabica extracts on cancerous cell line
Growth suppressing effect of Fagonia arabica extracts on cancerous cell line
Homeostasis of tissues requires a complex balance between cell proliferation and cell death. The disruption of this balanc...
Evaluation of the Ki-67 labeling index on immediate pre-ablation biopsies as a predictive biomarker of local recurrence of colorectal cancer liver metastases
Evaluation of the Ki-67 labeling index on immediate pre-ablation biopsies as a predictive biomarker of local recurrence of colorectal cancer liver metastases
The aim of this study was to evaluate if the Ki-67 labeling index (LI) on immediate pre-ablation biopsies of colorectal li...
S-Sulfocysteine’s toxic effects on HT-22 cells are not triggered by glutamate receptors, nor do they involve apoptotic or genotoxicity mechanisms
S-Sulfocysteine’s toxic effects on HT-22 cells are not triggered by glutamate receptors, nor do they involve apoptotic or genotoxicity mechanisms
S-Sulfocysteine (SSC) is a metabolite derived from the metabolism of sulfur-containing amino acids. It has been implicated...
N6-methyladenosine (m6A) RNA methylation of LncRNA LINC01214 accelerates the progression of non-small cell lung cancer (NSCLC) by targeting miR-195-5p/ROCK1 axis
N6-methyladenosine (m6A) RNA methylation of LncRNA LINC01214 accelerates the progression of non-small cell lung cancer (NSCLC) by targeting miR-195-5p/ROCK1 axis
Long non-coding RNA LINC01214 is reported to be up-regulated in non-small cell lung cancer (NSCLC), however, its function ...
Proposal for a non-adhesive single-cell culture technology for primary hepatocytes
Proposal for a non-adhesive single-cell culture technology for primary hepatocytes
Primary hepatocytes (PHs) are indispensable for studying liver function, drug screening, and regenerative medicine. Howeve...
The effect of exosomes from canine bone mesenchymal stem cells on IL-1β-mediated inflammatory responses in chondrocytes
The effect of exosomes from canine bone mesenchymal stem cells on IL-1β-mediated inflammatory responses in chondrocytes
Osteoarthritis is a degenerative disease of cartilage, and exosome derived from mesenchymal stem cells (MSCs) are consider...
miR-141-3p inhibited BPA-induced proliferation and migration of lung cancer cells through PTGER4
miR-141-3p inhibited BPA-induced proliferation and migration of lung cancer cells through PTGER4
The chemical substance bisphenol A (BPA) is widely used in household products, and its effect on human health has frequent...
CBX3 contributes to pancreatic adenocarcinoma progression via promoting KIF20A expression
CBX3 contributes to pancreatic adenocarcinoma progression via promoting KIF20A expression
Pancreatic adenocarcinoma (PAAD) is one of the malignant tumors with poor prognosis. This study aims to inquiry the effect...
Current opinion on pluripotent stem cell technology in Gaucher's disease: challenges and future prospects
Current opinion on pluripotent stem cell technology in Gaucher's disease: challenges and future prospects
Gaucher’s disease (GD) is a rare autosomal recessive genetic disorder caused by mutations in the GBA1 gene. Mutation...
Encyclopedia of Green Materials
Encyclopedia of Green Materials
This volume covers recent advances in the field of green materials and nanomaterials and their applications in electronics...
Oxidative stress profile and auto-antibodies production in Tunisian patients with COVID-19
Oxidative stress profile and auto-antibodies production in Tunisian patients with COVID-19
The clinical evidence, complications and the pathogenesis of COVID-19 are not clearly understood. In COVID-19 patients, ce...
Comparing the growth kinetics and characteristics of Wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums
Comparing the growth kinetics and characteristics of Wharton’s jelly derived mesenchymal stem cells expanded using different culture mediums
Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) can be isolated from umbilical cords which is abundant and ...
Silencing of LINC01278 promotes sensitivity of non-small cell lung cancer cells to osimertinib by targeting miR-324-3p/ZFX axis
Silencing of LINC01278 promotes sensitivity of non-small cell lung cancer cells to osimertinib by targeting miR-324-3p/ZFX axis
Osimertinib has been demonstrated to be effective for improving the prognosis of patients with epidermal growth factor rec...
High impact works on stem cell transplantation in intervertebral disc degeneration
High impact works on stem cell transplantation in intervertebral disc degeneration
Low back pain is a major disorder that causes disability and is strongly associated with intervertebral disc degeneration ...
Docetaxel treatment together with CTLA-4 knockdown enhances reduction of cell viability and amplifies apoptosis stimulation of MCF-7 breast cancer cells
Docetaxel treatment together with CTLA-4 knockdown enhances reduction of cell viability and amplifies apoptosis stimulation of MCF-7 breast cancer cells
Breast cancer is the most frequent cancer in women with a 20% mortality rate. The fate of patients suffering from breast c...
High mobility group protein N2 inhibits the progression of hepatocellular carcinoma and the related molecular mechanisms
High mobility group protein N2 inhibits the progression of hepatocellular carcinoma and the related molecular mechanisms
High mobility group protein N2 (HMGN2) related pathways are involved in chromatin regulation/acetylation. It has been repo...
Investigation of scaffold manufacturing conditions for 3-dimensional culture of myogenic cell line derived from black sea bream (Acanthopagrus schlegelii)
Investigation of scaffold manufacturing conditions for 3-dimensional culture of myogenic cell line derived from black sea bream (Acanthopagrus schlegelii)
Culturing fish myogenic cells in vitro holds significant potential to revolutionize aquaculture practices and support sust...
Effect of pH on antitumor activity of Chinese cobra (Naja atra) cytotoxin-XII
Effect of pH on antitumor activity of Chinese cobra (Naja atra) cytotoxin-XII
Cytotoxins (CTXs), proteins found in cobra venom, selectively inhibit tumor cell proliferation. Herein, we selected CTX-XI...
Bunyaviruses
Bunyaviruses
This volume explores advancements in the study of bunyaviruses, and covers virus manipulation, bunyavirus infection in ani...
Triptolide attenuates LPS-induced chondrocyte inflammation by inhibiting inflammasome activation via the Wnt/β-catenin and NF-κB signaling pathways
Triptolide attenuates LPS-induced chondrocyte inflammation by inhibiting inflammasome activation via the Wnt/β-catenin and NF-κB signaling pathways
Osteoarthritis (OA) is a common form of arthritis characterized by subchondral bone proliferation and articular cartilage ...
Phillygenin regulates the colorectal cancer tumor microenvironment by inhibiting hypoxia-inducible factor 1 alpha
Phillygenin regulates the colorectal cancer tumor microenvironment by inhibiting hypoxia-inducible factor 1 alpha
The tumor microenvironment (TME) is important in the recurrence and metastasis of colorectal cancer (CRC). Phillygenin is ...
The impact of graphene quantum dots on osteogenesis potential of Wharton’s jelly mesenchymal stem cells in fibrin hydrogel scaffolds
The impact of graphene quantum dots on osteogenesis potential of Wharton’s jelly mesenchymal stem cells in fibrin hydrogel scaffolds
Bone tissue engineering is a promising approach to overcome the limitations of traditional autograft bone transplantation....
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