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Use of Ubiquitous Chromatin Opening Elements (UCOE) as Tools to Maintain Transgene Expression in Biotechnology
Amongst the most important outputs of the biopharmaceutical industry are recombinant proteins, many of which are produced ...
In Silico and In Vitro Approaches Allow the Identification of the Prosystemin Molecular Network
Tomato Prosystemin (ProSys), the precursor of Systemin, a small peptidic hormone, is produced at very low concentration in...
Histone Variants and Chromatin Structure, Update of Advances
Available online 5 December 2022Author links open overlay panelAbstractHistone proteins are highly conserved among all euk...
Theranostic roles of machine learning in clinical management of kidney stone disease
Available online 5 December 2022Author links open overlay panelAbstractKidney stone disease (KSD) is a common illness caus...
Deconvolution algorithms for inference of the cell-type composition of the spatial transcriptome
Available online 5 December 2022Author links open overlay panelAbstractThe spatial transcriptome has enabled researchers t...
Interspecific and intraspecific Taylor's laws for frog skin microbes
Available online 5 December 2022Author links open overlay panelHighlights•Testing the scale invariance of Taylor’s laws in...
Recent functional insights into the magic role of (p)ppGpp in growth control
Available online 5 December 2022Author links open overlay panelAbstractRapid growth and survival are two key traits that e...
Meta-analysis of miR-34 target mRNAs using an integrative online application
Available online 6 December 2022Author links open overlay panelAbstractMembers of the microRNA-34/miR-34 family are induce...
Landscape of the intratumroal microenvironment in bladder cancer: Implications for prognosis and immunotherapy
Available online 1 December 2022Author links open overlay panelHighlights:•Our study presents the landscape of intratumora...
Evaluating GPCR modeling and docking strategies in the era of deep learning-based protein structure prediction
Available online 1 December 2022Author links open overlay panelAbstractWhile deep learning (DL) has brought a revolution i...
CapsNh-Kcr: capsule network-based prediction of lysine crotonylation sites in human non-histone proteins
Lysine crotonylation (Kcr) is one of the most important post-translational modifications (PTMs) that is widely detected in...
ChEAP: ChIP-exo Analysis Pipeline and the investigation of Escherichia coli RpoN protein-DNA interactions
Available online 2 December 2022Author links open overlay panelAbstractGenome-scale studies of the bacterial regulatory ne...
A guide to multi-omics data collection and integration for translational medicine
Available online 1 December 2022Author links open overlay panelAbstractThe emerging high-throughput technologies have led ...
scDrug: From single-cell RNA-seq to drug response prediction
Available online 1 December 2022Author links open overlay panelAbstractSingle-cell RNA sequencing (scRNA-seq) technology a...
Time-course RNA-Seq profiling reveals isoform-level gene expression dynamics of the cGAS-STING pathway
The cGAS-STING pathway, orchestrating complicated transcriptome-wide immune responses, is essential for host antiviral def...
Paralog Explorer: a resource for mining information about paralogs in common research organisms
Available online 24 November 2022Author links open overlay panelAbstractParalogs are genes which arose via gene duplicatio...
The dynamic landscape of peptide activity prediction
Available online 24 November 2022Author links open overlay panelAbstractPeptides are known to possess a plethora of benefi...
Rhizosphere microbes enhance plant salt tolerance: toward crop production in saline soil
Available online 25 November 2022Author links open overlay panelAbstractThe world’s population continues to increase and t...
N1-methyladenosine modification in cancer biology: current status and future perspectives
Available online 25 November 2022Author links open overlay panelAbstractPost-transcriptional modifications in RNAs regulat...
Accurate protein stability predictions from homology models
Available online 25 November 2022Author links open overlay panelAbstractCalculating changes in protein stability (ΔΔG) has...