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Post-transcriptional & post-translational control of gene expression in the inner ear
Moving beyond the central dogma of genetics in auditory and vestibular neurobiologyIn 1953, James Watson and Francis Crick...
Cognitive Control in Age-Related Hearing Loss: A Narrative Review
Age-related hearing loss (ARHL) is a chronic condition in older adults (Collins, 1997; Cruickshanks et al., 2003; Quaranta...
Chromodomain Helicase DNA Binding Protein 4 in Cell Fate Decisions
Spiral ganglion neurons (SGNs) relay acoustic information from sensory hair cells to central auditory circuits. Ototoxic d...
Linear mixed-effect modeling of organ of Corti vibratory tuning curves
Optical coherence tomography (OCT) has proven to be a major technological advance in auditory research for the measurement...
The cochlea is built to last a lifetime
Orchestration of protein production and degradation and the regulation of protein lifetimes play a central role in many ba...
Mechanisms of masking by Schroeder-phase harmonic tone complexes in the budgerigar (Melopsittacus undulatus)
Schroeder's algorithm can produce harmonic tone complexes (HTCs) with a flat temporal envelope and either upward- or downw...
Supporting-cell vs. hair-cell survival in the human cochlea: Implications for regenerative therapies
Much of the threshold elevations that define permanent sensorineural hearing loss in humans are due to irreversible loss o...
Abnormal auditory brainstem responses in an animal model of autism spectrum disorder
Autism spectrum disorder (ASD) is a developmental disability associated with social, communication and behavioral challeng...
Intracochlear Pressure and Temporal Bone Motion Interaction under Bone Conduction Stimulation
Under bone conduction (BC) stimulation, the sound energy propagates from the stimulation site to both cochleae via five ma...
The actin cytoskeleton in hair bundle development and hearing loss
The inner ear houses the auditory and vestibular end organs, which are responsible for the sensation of hearing and balanc...
Development and evaluation of helper dependent adenoviral vectors for inner ear gene delivery
Hearing loss impacts over 5% of the world population and has debilitating effects on communication which lead to increased...
The effect of rhythm on selective listening in multiple-source environments for young and older adults
Difficulty understanding speech in noisy environments is one of the most common problems reported by older listeners. This...
Spread of the intracochlear electrical field: Implications for assessing electrode array location in cochlear implantation
The electrode-generated intracochlear electrical field (EF) spreads widely along the scala tympani surrounded by poorly-co...
Effects of sensorineural hearing loss on formant-frequency discrimination: Measurements and models
Available online 8 May 2023, 108788Author links open overlay panel, , , , , , ABSTRACTThis study concerns the effect of he...
Effect of age on lateralized auditory processing
The lateralization of processing in the auditory cortex varies for different acoustic features. Extracting the meaning of ...
Role of mitochondrial dysfunction and oxidative stress in sensorineural hearing loss
Hearing loss has emerged as a major public health concern with significant social and economic implications. According to ...
Hearing Preservation in Cochlear Implantation
A. Dhanasingh et al.An overview of cochlear implant electrode array designsHear Res(2017)O. Adunka et al.Development and e...
Delta-band neural envelope tracking predicts speech intelligibility in noise in preschoolers
Globally, 34 million children (∼0.2% of all children aged 0 to 18 years) have disabling hearing loss, i.e., hearing loss g...
Analysis of cross-talk cancellation of bilateral bone conduction stimulation
Bone conduction (BC) hearing refers to the way vibratory sound waves pass through the skull to the cochlea to produce an a...
Hepatocyte growth factor mimetic confers protection from aminoglycoside-induced hair cell death in vitro
Hearing loss and vestibular dysfunction are common debilitating disorders resulting from a wide variety of conditions incl...
Spatio-temporal pattern of c-Jun N-terminal kinase isoforms in the cochleae of C57BL/6J mice with presbycusis
Mitogen-activated protein kinase (MAPK) cascade is a signaling pathway stimulated by many environmental stressors, and it ...
Measurements of ear-canal geometry from high-resolution CT scans of human adult ears
Description of the ear canal’s geometry is important for understanding peripheral sound flow, yet anatomical measurements ...
Hearing Research Special Issue: Mitochondrial Function and Dysfunction in the Inner Ear
Hearing loss has emerged as a major public health concern with significant social and economic implications. According to ...
Stability of complex sound representations in the auditory midbrain across the lifespan despite age-related brainstem delays
Auditory brainstemAuditory midbrainInferior colliculusGap detectionTemporal resolutionTemporal processingAuditory brainste...
Effects of Age on Brainstem Coding of Speech Glimpses in Interrupted Noise
Speech communication in background noise is particularly difficult for older adults—even those with normal hearing thresho...
A new paradigm of hearing loss and preservation with cochlear implants: Learnings from fundamental studies and clinical research
Hearing preservation has shaped the cochlear implant (CI) industry for the greater part of the past two decades, being a t...
The effect of topic familiarity and volatility of auditory scene on selective auditory attention
Selective auditory attention has been suggested as underlying the “cocktail party effect,” which describes listening to a ...
Functional network properties of the auditory cortex
A fundamental goal of the auditory system is to parse an unlabeled mixture of environmental auditory stimuli into coherent...