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Metanephric stromal tumor with BRAF V600E mutation in an adult patient: Case report and literature review
Metanephric stromal tumor with BRAF V600E mutation in an adult patient: Case report and literature review
Metanephric stromal tumor (MST) is a rare, benign pediatric renal neoplasm of uncertain histogenesis that belongs to the m...
Feasibility of a CT-based lymph node radiomics nomogram in detecting lymph node metastasis in PDAC patients
Feasibility of a CT-based lymph node radiomics nomogram in detecting lymph node metastasis in PDAC patients
ObjectivesTo investigate the potential value of a contrast enhanced computed tomography (CECT)-based radiological-radiomic...
PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma
PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma
BackgroundOsteosarcoma (OS) is the most common primary malignant bone tumors in children and adolescents. Procollagen-lysi...
Laparoscopic treatment for an intrapancreatic accessory spleen: A case report
Laparoscopic treatment for an intrapancreatic accessory spleen: A case report
Malignant pancreatic tumors have early metastasis, aggressive behavior and poor prognosis. Surgeons often need to judge wh...
A comparative study of robotics and laparoscopic in minimally invasive pancreatoduodenectomy: A single-center experience
A comparative study of robotics and laparoscopic in minimally invasive pancreatoduodenectomy: A single-center experience
ObjectiveTo retrospectively compare the short-term benefits of robotic surgery and laparoscopic in the perioperative perio...
Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly
Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly
Pancreatic cancer is a devastating disease with a dismal prognosis and poor treatment outcomes. Searching for new agents f...
Antitumor effect and mechanism of FZD7 polypeptide vaccine
Antitumor effect and mechanism of FZD7 polypeptide vaccine
The resistant cells that proliferate after radiotherapy and chemotherapy are primarily tumor stem cells with high stem mar...
Inhibition of induced-hepatic cancer in vivo through IQGAP1-shRNA gene therapy and modulation of TRAIL-induced apoptosis pathway
Inhibition of induced-hepatic cancer in vivo through IQGAP1-shRNA gene therapy and modulation of TRAIL-induced apoptosis pathway
BackgroundLiver cancer is the deadliest malignancy among common tumors. It is the top cause of cancer-related deaths in Eg...
Treatment options for acute myeloid leukemia patients aged <60 years
Treatment options for acute myeloid leukemia patients aged <60 years
Treatment of acute myeloid leukemia (AML) has changed over the last few years, after the discovery of new drugs selectivel...
Amino acid metabolism in primary bone sarcomas
Amino acid metabolism in primary bone sarcomas
Primary bone sarcomas, including osteosarcoma (OS) and Ewing sarcoma (ES), are aggressive tumors with peak incidence in ch...
Hepatic macrophage mediated immune response in liver steatosis driven carcinogenesis
Hepatic macrophage mediated immune response in liver steatosis driven carcinogenesis
Obesity confers an independent risk for carcinogenesis. Classically viewed as a genetic disease, owing to the discovery of...
A novel association of pyroptosis-related gene signature with the prognosis of hepatocellular carcinoma
A novel association of pyroptosis-related gene signature with the prognosis of hepatocellular carcinoma
BackgroundHepatocellular carcinoma (HCC) is one of the global leading lethal tumors. Pyroptosis has recently been defined ...
Update in collecting duct carcinoma: Current aspects of the clinical and molecular characterization of an orphan disease
Update in collecting duct carcinoma: Current aspects of the clinical and molecular characterization of an orphan disease
Collecting duct renal cell carcinoma (cdRCC), which until recently was thought to arise from the collecting ducts of Belli...
Pediatric non–Down’s syndrome acute megakaryoblastic leukemia patients in China: A single center's real-world analysis
Pediatric non–Down’s syndrome acute megakaryoblastic leukemia patients in China: A single center's real-world analysis
Non-Down’s syndrome acute megakaryocytic leukemia (non-DS-AMKL) is a subtype of childhood acute myeloid leukemia (AML), wh...
Childhood brain tumors: It is the child’s brain that really matters
Childhood brain tumors: It is the child’s brain that really matters
driven therapies. Contemporary bioscience thinking however has responded in particular to the challenges of this primary r...
Spectral CT for preoperative prediction of lymphovascular invasion in resectable gastric cancer: With external prospective validation
Spectral CT for preoperative prediction of lymphovascular invasion in resectable gastric cancer: With external prospective validation
ObjectivesTo develop and externally validate a spectral CT based nomogram for the preoperative prediction of LVI in patien...
Gut microbiota changes and biological mechanism in hepatocellular carcinoma after transarterial chemoembolization treatment
Gut microbiota changes and biological mechanism in hepatocellular carcinoma after transarterial chemoembolization treatment
Background and aimsIntestinal flora is closely associated with the occurrence and development of hepatocellular carcinoma ...
Setup error assessment based on “Sphere-Mask” Optical Positioning System: Results from a multicenter study
Setup error assessment based on “Sphere-Mask” Optical Positioning System: Results from a multicenter study
BackgroundThe setup accuracy plays an extremely important role in the local control of tumors. The purpose of this study i...
Development and feasibility evaluation of an AR-assisted radiotherapy positioning system
Development and feasibility evaluation of an AR-assisted radiotherapy positioning system
PurposeThe aim of this study is to develop an augmented reality (AR)–assisted radiotherapy positioning system based on Hol...
Identification of fatty acid signature to predict prognosis and guide clinical therapy in patients with ovarian cancer
Identification of fatty acid signature to predict prognosis and guide clinical therapy in patients with ovarian cancer
High-grade serous ovarian cancer (HGSOC) is a heterogeneous cancer characterized by high relapse rate. Approximately 80% o...