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The Renaissance of Reproductive Science: Leonardo da Vinci’s Anatomical Contributions
The Renaissance of Reproductive Science: Leonardo da Vinci’s Anatomical Contributions
Leonardo de Vinci is considered one of the greatest artists that has ever lived. His work includes the Mona Lisa and The L...
Chronic Endometritis and Endometriosis: Two Sides of the Same Coin?
Chronic Endometritis and Endometriosis: Two Sides of the Same Coin?
Both chronic endometritis and endometriosis are common entities in infertile patients. The association and the co-existenc...
The BMP Signaling Pathway: Bridging Maternal-Fetal Crosstalk in Early Pregnancy
The BMP Signaling Pathway: Bridging Maternal-Fetal Crosstalk in Early Pregnancy
The maintenance of early pregnancy is a complex and distinctive process, primarily characterized by critical reproductive ...
Methotrexate fixed dosing protocol for ambulatory treatment of ectopic pregnancy
Methotrexate fixed dosing protocol for ambulatory treatment of ectopic pregnancy
The primary objective of this study was to review a methotrexate 90-mg fixed-dose protocol for treatment of ectopic pregna...
In vitro Fertilization Outcomes of Frozen–thawed Embryo Transfer with Hatched Blastocysts versus with Hatching Blastocysts
In vitro Fertilization Outcomes of Frozen–thawed Embryo Transfer with Hatched Blastocysts versus with Hatching Blastocysts
This study aimed to elucidate the effect of hatching status on in vitro fertilization (IVF) outcomes in frozen–thawe...
Voltage-Gated Calcium Channels and the Parity-Dependent Differential Uterine Response to Oxytocin in Rats
Voltage-Gated Calcium Channels and the Parity-Dependent Differential Uterine Response to Oxytocin in Rats
The experience of pregnancy affects uterine function well beyond delivery. We previously demonstrated that the response to...
Ultra-Fast Warming Procedure of Vitrified Blastocysts Results in Maintained Embryology and Clinical Outcomes
Ultra-Fast Warming Procedure of Vitrified Blastocysts Results in Maintained Embryology and Clinical Outcomes
Vitrification has revolutionized embryo cryopreservation, but represents a significant workload in the IVF lab. We evaluat...
Matrix Metallopeptidase 9 Promotes Contraction in Human Uterine Myometrium
Matrix Metallopeptidase 9 Promotes Contraction in Human Uterine Myometrium
Matrix metallopeptidase 9 (MMP9) is a secreted zinc-dependent peptidase known for extracellular remodeling. MMP9 is elevat...
Only Children by Choice vs. Only Children by Circumstances: Why Do Some Women Have Only One Child?
Only Children by Choice vs. Only Children by Circumstances: Why Do Some Women Have Only One Child?
In an attempt to stimulate further theory and research on only children, we introduce two conceptual distinctions: Only ch...
A Multimodal Approach to Symptomatic Endometriosis: A Proposed Algorithm for Clinical Management
A Multimodal Approach to Symptomatic Endometriosis: A Proposed Algorithm for Clinical Management
Recent research has proven that peripheral (PS) and central sensitization (CS), mental health, and myofascial dysfunction ...
Reclassifying a Novel POMT1 Variant by Integrating Functional Analysis and Bioinformatics: Implications for Preimplantation Genetic Testing
Reclassifying a Novel POMT1 Variant by Integrating Functional Analysis and Bioinformatics: Implications for Preimplantation Genetic Testing
The advancement of next-generation sequencing has spurred the growing adoption of whole-exome sequencing (WES) for genetic...
Research Hotspots and Thematic Trends in the Management of Preeclampsia: A Bibliometric Analysis from 2000 to 2022
Research Hotspots and Thematic Trends in the Management of Preeclampsia: A Bibliometric Analysis from 2000 to 2022
Preeclampsia (PE) is one of the serious complications of pregnancy, and the management of PE remains an important problem ...
Beneficial Effects of Pomegranate Extracts for Benign Gynecologic Disorders
Beneficial Effects of Pomegranate Extracts for Benign Gynecologic Disorders
Pomegranate (Punica granatum) is a widely cultivated fruit historically recognized for its health benefits and is regarded...
Evaluation of the In Vivo Efficacy of the JAK Inhibitor AZD1480 in Uterine Leiomyomas Using a Patient-derived Xenograft Murine Model
Evaluation of the In Vivo Efficacy of the JAK Inhibitor AZD1480 in Uterine Leiomyomas Using a Patient-derived Xenograft Murine Model
Uterine leiomyomas are common noncancerous hormonally-dependent neoplasms comprised of uterine smooth-muscle cells and fib...
The Microbiome Landscape of Adenomyosis: A Systematic Review
The Microbiome Landscape of Adenomyosis: A Systematic Review
Alterations in the microbiome composition have been identified in common gynecologic pathologies such as endometriosis car...
Mid-Pregnancy Placental Transcriptome in a Model of Placental Insufficiency with and without Novel Intervention
Mid-Pregnancy Placental Transcriptome in a Model of Placental Insufficiency with and without Novel Intervention
Fetal growth restriction (FGR) affects between 5-10% of all live births. Placental insufficiency is a leading cause of FGR...
Placental and Fetal Metabolic Reprogramming in Pregnancies with Intrauterine Growth Restriction
Placental and Fetal Metabolic Reprogramming in Pregnancies with Intrauterine Growth Restriction
The high-altitude hypoxia model demonstrates that insufficiently oxygenated placentas activate compensatory mechanisms to ...
Circ_0008440 Inhibits Proliferation and Promotes Apoptosis of Trophoblast Cells through the miR-194-5p/PFKFB2 Axis
Circ_0008440 Inhibits Proliferation and Promotes Apoptosis of Trophoblast Cells through the miR-194-5p/PFKFB2 Axis
Preeclampsia (PE), an idiopathic hypertensive disorder that arises during pregnancy, poses a serious threat to the health ...
Circulating microRNAs in Body Fluid: “Fingerprint” RNA Snippets Deeply Impact Reproductive Biology
Circulating microRNAs in Body Fluid: “Fingerprint” RNA Snippets Deeply Impact Reproductive Biology
Circulating miRNAs (C-miRNAs) occuring in a cell-free form within body fluids and other extracellular environments have ga...
Association of Parity with Type 2 Diabetes Mellitus in Japan
Association of Parity with Type 2 Diabetes Mellitus in Japan
This study investigates the association between parity and type 2 diabetes mellitus (T2DM) in Japanese women, considering ...
Oxidative and Endoplasmic Reticulum Stress Mediate Testicular Injury in a Rat Model of Varicocele
Oxidative and Endoplasmic Reticulum Stress Mediate Testicular Injury in a Rat Model of Varicocele
Evidence of endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) have been increasingly...
Probiotics Combined with Metformin Improves Sperm Parameters in Obese Male Mice through Modulation of Intestinal Microbiota Equilibrium
Probiotics Combined with Metformin Improves Sperm Parameters in Obese Male Mice through Modulation of Intestinal Microbiota Equilibrium
The decline in sperm parameters among obese males has attracted significant scholarly interest. The intestinal microbiota ...