SCI时时刷

search
Targeting inflammation as cancer therapy
Targeting inflammation as cancer therapy
Inflammation has accompanied human beings since the emergence of wounds and infections. In the past decades, numerous effo...
Decoding the glycoproteome: a new frontier for biomarker discovery in cancer
Decoding the glycoproteome: a new frontier for biomarker discovery in cancer
Cancer early detection and treatment response prediction continue to pose significant challenges. Cancer liquid biopsies f...
Optical nanomaterial-based detection of biomarkers in liquid biopsy
Optical nanomaterial-based detection of biomarkers in liquid biopsy
Liquid biopsy, which is a minimally invasive procedure as an alternative to tissue biopsy, has been introduced as a new di...
FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion
FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion
Emerging evidences suggest that aberrant metabolites contributes to the immunosuppressive microenvironment that leads to c...
METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
While liver cancer stem cells (CSCs) play a crucial role in hepatocellular carcinoma (HCC) initiation, progression, recurr...
Metabolic reprogramming in the tumor microenvironment of liver cancer
Metabolic reprogramming in the tumor microenvironment of liver cancer
The liver is essential for metabolic homeostasis. The onset of liver cancer is often accompanied by dysregulated liver fun...
cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment
cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment
Cancer is a complex disease resulting from abnormal cell growth that is induced by a number of genetic and environmental f...
Vaccines: a promising therapy for myelodysplastic syndrome
Vaccines: a promising therapy for myelodysplastic syndrome
Myelodysplastic neoplasms (MDS) define clonal hematopoietic malignancies characterized by heterogeneous mutational and cli...
The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
Antibody-drug conjugates (ADCs) represent an important class of cancer therapies that have revolutionized the treatment pa...
Phase separations in oncogenesis, tumor progressions and metastasis: a glance from hallmarks of cancer
Phase separations in oncogenesis, tumor progressions and metastasis: a glance from hallmarks of cancer
Liquid–liquid phase separation (LLPS) is a novel principle for interpreting precise spatiotemporal coordination in l...
Multiscale protein networks systematically identify aberrant protein interactions and oncogenic regulators in seven cancer types
Multiscale protein networks systematically identify aberrant protein interactions and oncogenic regulators in seven cancer types
Global proteomic data generated by advanced mass spectrometry (MS) technologies can help bridge the gap between genome/tra...
Considerations for the design of antibody drug conjugates (ADCs) for clinical development: lessons learned
Considerations for the design of antibody drug conjugates (ADCs) for clinical development: lessons learned
Antibody–drug conjugates (ADCs) have emerged as a novel therapeutic strategy that has successfully reached patient t...
Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy
Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation of inflammatory responses is a...
Novel research and future prospects of artificial intelligence in cancer diagnosis and treatment
Novel research and future prospects of artificial intelligence in cancer diagnosis and treatment
Research into the potential benefits of artificial intelligence for comprehending the intricate biology of cancer has grow...
Genitourinary cancers updates: highlights from ASCO 2023
Genitourinary cancers updates: highlights from ASCO 2023
Significant scientific advances in immunotherapy and targeted therapy approaches have improved clinical outcomes and incre...
Direct inhibition of dioxygenases TET1 by the rheumatoid arthritis drug auranofin selectively induces cancer cell death in T-ALL
Direct inhibition of dioxygenases TET1 by the rheumatoid arthritis drug auranofin selectively induces cancer cell death in T-ALL
T-cell acute lymphoblastic leukemia (T-ALL) is a type of hematologic tumor with malignant proliferation of hematopoietic p...
Outcomes of patients with secondary central nervous system lymphoma following CAR T-cell therapy: a multicenter cohort study
Outcomes of patients with secondary central nervous system lymphoma following CAR T-cell therapy: a multicenter cohort study
Chimeric antigen receptor T-cell therapy (CAR-T) has been successful in treating relapsed/refractory B-cell lymphomas. How...
Reprogramming T cell differentiation and exhaustion in CAR-T cell therapy
Reprogramming T cell differentiation and exhaustion in CAR-T cell therapy
T cell differentiation is a highly regulated, multi-step process necessary for the progressive establishment of effector f...
CRISPR screening in hematology research: from bulk to single-cell level
CRISPR screening in hematology research: from bulk to single-cell level
The CRISPR genome editing technology has revolutionized the way gene function is studied. Genome editing can be achieved i...