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The Brain's Sensitivity to Sensory Error Can Be Modulated by Altering Perceived Variability
The Brain's Sensitivity to Sensory Error Can Be Modulated by Altering Perceived Variability
When individuals make a movement that produces an unexpected outcome, they learn from the resulting error. This process, e...
Circuit Reorganization of Subicular Cell-Type-Specific Interneurons in Temporal Lobe Epilepsy
Circuit Reorganization of Subicular Cell-Type-Specific Interneurons in Temporal Lobe Epilepsy
The subiculum represents a crucial brain pivot in regulating seizure generalization in temporal lobe epilepsy (TLE), prima...
Regulation of Sleep Amount by CRTC1 via Transcription of Crh in Mice
Regulation of Sleep Amount by CRTC1 via Transcription of Crh in Mice
The cAMP response element binding protein (CREB) is required for regulation of daily sleep amount, whereas gain of functio...
The Anterior Insula Engages in Feature- and Context-Level Predictive Coding Processes for Recognition Judgments
The Anterior Insula Engages in Feature- and Context-Level Predictive Coding Processes for Recognition Judgments
Predictive coding mechanisms facilitate detection and perceptual recognition, thereby influencing recognition judgements, ...
Complementary Organization of Mouse Driver and Modulator Cortico-thalamo-cortical Circuits
Complementary Organization of Mouse Driver and Modulator Cortico-thalamo-cortical Circuits
AbstractCorticocortical (CC) projections in the visual system facilitate hierarchical processing of sensory information. I...
Social Risk Coding by Amygdala Activity and Connectivity with the Dorsal Anterior Cingulate Cortex
Social Risk Coding by Amygdala Activity and Connectivity with the Dorsal Anterior Cingulate Cortex
Risk is a fundamental factor affecting individual and social economic decisions, but its neural correlates are largely une...
Diverse Frontoparietal Connectivity Supports Semantic Prediction and Integration in Sentence Comprehension
Diverse Frontoparietal Connectivity Supports Semantic Prediction and Integration in Sentence Comprehension
AbstractPredictive processing in the parietal, temporal, frontal, and sensory cortex allows us to anticipate future meanin...
Delayed Accumulation of Inhibitory Input Explains Gamma Frequency Variation with Changing Contrast in an Inhibition Stabilized Network
Delayed Accumulation of Inhibitory Input Explains Gamma Frequency Variation with Changing Contrast in an Inhibition Stabilized Network
Gamma rhythm (30–70 Hz), thought to represent the interactions between excitatory and inhibitory populations, can be induc...
GlyT2-Positive Interneurons Regulate Timing and Variability of Information Transfer in a Cerebellar-Behavioral Loop
GlyT2-Positive Interneurons Regulate Timing and Variability of Information Transfer in a Cerebellar-Behavioral Loop
IntroductionThe cerebellum is implicated in a diverse range of behaviors, extending from simple reflexes to complex functi...
Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-A{beta} Antibody-Injected Cortex
Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-A{beta} Antibody-Injected Cortex
IntroductionAlzheimer's disease (AD) is a leading cause of dementia affecting approximately 10.8% of Americans over the ag...
Individual Variability in the Structural Connectivity Architecture of the Human Brain
Individual Variability in the Structural Connectivity Architecture of the Human Brain
The human brain exhibits a high degree of individual variability in both its structure and function, which underlies inter...
High-Density Recording Reveals Sparse Clusters (But Not Columns) for Shape and Texture Encoding in Macaque V4
High-Density Recording Reveals Sparse Clusters (But Not Columns) for Shape and Texture Encoding in Macaque V4
Macaque area V4 includes neurons that exhibit exquisite selectivity for visual form and surface texture, but their functio...
Erratum: Binder et al., "Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways"
Erratum: Binder et al., "Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways"
In the article, “Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellu...
New Perspective of the Persistent Gender and Diversity Gap in Nobel Prizes
New Perspective of the Persistent Gender and Diversity Gap in Nobel Prizes
Despite significant strides in gender equity, the Nobel Prizes in STEM fields continue to exhibit glaring disparities in t...
EphA4 Mediates EphrinB1-Dependent Adhesion in Retinal Ganglion Cells
EphA4 Mediates EphrinB1-Dependent Adhesion in Retinal Ganglion Cells
Eph/ephrin signaling is crucial for organizing retinotopic maps in vertebrates. Unlike other EphAs, which are expressed in...
Neuropeptidergic Input from the Lateral Hypothalamus to the Suprachiasmatic Nucleus Alters the Circadian Period in Mice
Neuropeptidergic Input from the Lateral Hypothalamus to the Suprachiasmatic Nucleus Alters the Circadian Period in Mice
In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus, which transmi...
Auditory Rhythm Encoding during the Last Trimester of Human Gestation: From Tracking the Basic Beat to Tracking Hierarchical Nested Temporal Structures
Auditory Rhythm Encoding during the Last Trimester of Human Gestation: From Tracking the Basic Beat to Tracking Hierarchical Nested Temporal Structures
AbstractRhythm perception and synchronization to periodicity hold fundamental neurodevelopmental importance for language a...
Striosome Circuitry Stimulation Inhibits Striatal Dopamine Release and Locomotion
Striosome Circuitry Stimulation Inhibits Striatal Dopamine Release and Locomotion
The mammalian striatum is divided into two types of anatomical structures: the island-like, μ-opioid receptor (MOR)-rich s...
Multitasking Practice Eliminates Modality-Based Interference by Separating Task Representations in Sensory Brain Regions
Multitasking Practice Eliminates Modality-Based Interference by Separating Task Representations in Sensory Brain Regions
The debate on the neural basis of multitasking costs evolves around neural overlap between concurrently performed tasks. R...
Activity-Dependent Internalization of Glun2B-Containing NMDARs Is Required for Synaptic Incorporation of Glun2A and Synaptic Plasticity
Activity-Dependent Internalization of Glun2B-Containing NMDARs Is Required for Synaptic Incorporation of Glun2A and Synaptic Plasticity
NMDA-type glutamate receptors are heterotetrameric complexes composed of two GluN1 and two GluN2 subunits. The precise com...
Spatial Mapping of Activity Changes across Sensory Areas Following Visual Deprivation in Adults
Spatial Mapping of Activity Changes across Sensory Areas Following Visual Deprivation in Adults
Loss of a sensory modality triggers global adaptation across brain areas, allowing the remaining senses to guide behavior ...
Fast-Spike Interneurons in Visual Cortical Layer 5: Heterogeneous Response Properties Are Related to Thalamocortical Connectivity
Fast-Spike Interneurons in Visual Cortical Layer 5: Heterogeneous Response Properties Are Related to Thalamocortical Connectivity
Layer 4 (L4) of rabbit V1 contains fast-spike GABAergic interneurons (suspected inhibitory interneurons, SINs) that receiv...
Synapse-to-Nucleus ERK->CREB Transcriptional Signaling Requires Dendrite-to-Soma Ca2+ Propagation Mediated by L-Type Voltage-Gated Ca2+ Channels
Synapse-to-Nucleus ERK->CREB Transcriptional Signaling Requires Dendrite-to-Soma Ca2+ Propagation Mediated by L-Type Voltage-Gated Ca2+ Channels
The cAMP-response element–binding protein (CREB) transcription factor controls the expression of the neuronal immediate ea...
Tug-of-War: Orexin and Dynorphin Effects on Reward Processing Circuits
Tug-of-War: Orexin and Dynorphin Effects on Reward Processing Circuits
Day-to-day decision-making and long-term goal pursuit require circuits that mediate reward and motivation. It is essential...
Multivariate Pattern Analysis of EEG Reveals Neural Mechanism of Naturalistic Target Processing in Attentional Blink
Multivariate Pattern Analysis of EEG Reveals Neural Mechanism of Naturalistic Target Processing in Attentional Blink
The human brain has inherent limitations in consciously processing visual information. When individuals monitor a rapid se...
Repetitive Sensory Stimulation Potentiates and Recruits Sensory-Evoked Cortical Population Activity
Repetitive Sensory Stimulation Potentiates and Recruits Sensory-Evoked Cortical Population Activity
Sensory experience and learning are thought to be associated with plasticity of neocortical circuits. Repetitive sensory s...
Parietofrontal Networks Mediate Contextual Influences in the Appraisal of Pain and Disgust Facial Expressions
Parietofrontal Networks Mediate Contextual Influences in the Appraisal of Pain and Disgust Facial Expressions
We appraise other people’s emotions by combining multiple sources of information, including somatic facial/body reactions ...
The Relationship between White Matter Architecture and Language Lateralization in the Healthy Brain
The Relationship between White Matter Architecture and Language Lateralization in the Healthy Brain
Study data and participantsAll data were acquired from the Human Connectome Project (HCP; http://www.humanconnectome.org/)...
Restoring Compromised Cl- in D2 Neurons of a Huntingtons Disease Mouse Model Rescues Motor Disability
Restoring Compromised Cl- in D2 Neurons of a Huntingtons Disease Mouse Model Rescues Motor Disability
Figure 3. KCC2 function is altered specifically in D2 MSNs of R6/2 mice. A, Image showing infection site of AAV5-mCherry i...
Disruption of the Autism-Associated Pcdh9 Gene Leads to Transcriptional Alterations, Synapse Overgrowth, and Defective Network Activity in the CA1
Disruption of the Autism-Associated Pcdh9 Gene Leads to Transcriptional Alterations, Synapse Overgrowth, and Defective Network Activity in the CA1
Protocadherins, a family of adhesion molecules with a crucial role in cell–cell interactions, have emerged as key players ...
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