SCI时时刷

search
Neuroscience Milestones: Developing Standardized Core-Competencies for Research-Based Neuroscience Trainees
Neuroscience Milestones: Developing Standardized Core-Competencies for Research-Based Neuroscience Trainees
In the medical field, the implementation of Milestones by the Accreditation Council for Graduate Medical Education (ACGME)...
Glycerol-3-Phosphate Shuttle Is a Backup System Securing Metabolic Flexibility in Neurons
Glycerol-3-Phosphate Shuttle Is a Backup System Securing Metabolic Flexibility in Neurons
Electrical activity in neurons is highly energy demanding and accompanied by rises in cytosolic Ca2+. Cytosolic Ca2+, in t...
Antagonistic Activities of Fmn2 and ADF Regulate Axonal F-Actin Patch Dynamics and the Initiation of Collateral Branching
Antagonistic Activities of Fmn2 and ADF Regulate Axonal F-Actin Patch Dynamics and the Initiation of Collateral Branching
Interstitial collateral branching of axons is a critical component in the development of functional neural circuits. Axon ...
Offset Responses in the Auditory Cortex Show Unique History Dependence
Offset Responses in the Auditory Cortex Show Unique History Dependence
IntroductionA universal feature of sensory processing is that the brain's response to a sensory stimulus depends on the re...
Selective Enhancement of Post-Sleep Visual Motion Perception by Repetitive Tactile Stimulation during Sleep
Selective Enhancement of Post-Sleep Visual Motion Perception by Repetitive Tactile Stimulation during Sleep
Tactile sensations can bias visual perception in the awake state while visual sensitivity is known to be facilitated by sl...
Interfacing Motor Units in Nonhuman Primates Identifies a Principal Neural Component for Force Control Constrained by the Size Principle
Interfacing Motor Units in Nonhuman Primates Identifies a Principal Neural Component for Force Control Constrained by the Size Principle
Motor units convert the last neural code of movement into muscle forces. The classic view of motor unit control is that th...
Robust Effects of Working Memory Demand during Naturalistic Language Comprehension in Language-Selective Cortex
Robust Effects of Working Memory Demand during Naturalistic Language Comprehension in Language-Selective Cortex
To understand language, we must infer structured meanings from real-time auditory or visual signals. Researchers have long...
Connectivity-Defined Subdivisions of the Intraparietal Sulcus Respond Differentially to Abstraction during Decision-Making
Connectivity-Defined Subdivisions of the Intraparietal Sulcus Respond Differentially to Abstraction during Decision-Making
The intraparietal sulcus (IPS) has been implicated in numerous functions that range from representation of visual stimuli ...
Speech Understanding Oppositely Affects Acoustic and Linguistic Neural Tracking in a Speech Rate Manipulation Paradigm
Speech Understanding Oppositely Affects Acoustic and Linguistic Neural Tracking in a Speech Rate Manipulation Paradigm
When listening to continuous speech, the human brain can track features of the presented speech signal. It has been shown ...
Ventral Hippocampal Formation Is the Primary Epileptogenic Zone in a Rat Model of Temporal Lobe Epilepsy
Ventral Hippocampal Formation Is the Primary Epileptogenic Zone in a Rat Model of Temporal Lobe Epilepsy
Temporal lobe epilepsy is common, but mechanisms of seizure initiation are unclear. We evaluated seizure initiation in fem...
STAT1 Contributes to Microglial/Macrophage Inflammation and Neurological Dysfunction in a Mouse Model of Traumatic Brain Injury
STAT1 Contributes to Microglial/Macrophage Inflammation and Neurological Dysfunction in a Mouse Model of Traumatic Brain Injury
Traumatic brain injury (TBI) triggers a plethora of inflammatory events in the brain that aggravate secondary injury and i...
p140Cap Regulates the Composition and Localization of the NMDAR Complex in Synaptic Lipid Rafts
p140Cap Regulates the Composition and Localization of the NMDAR Complex in Synaptic Lipid Rafts
The NMDARs are key players in both physiological and pathologic synaptic plasticity because of their involvement in many a...
Afferent Loss, GABA, and Central Gain in Older Adults: Associations with Speech Recognition in Noise
Afferent Loss, GABA, and Central Gain in Older Adults: Associations with Speech Recognition in Noise
Deficits in auditory nerve (AN) function for older adults reduce afferent input to the cortex. The extent to which the cor...
Layer-Specific Developmentally Precise Axon Targeting of Transient Suppressed-by-Contrast Retinal Ganglion Cells
Layer-Specific Developmentally Precise Axon Targeting of Transient Suppressed-by-Contrast Retinal Ganglion Cells
The mouse retina encodes diverse visual features in the spike trains of >40 retinal ganglion cell (RGC) types. Each RGC...
Enhancement of Hippocampal-Thalamocortical Temporal Coordination during Slow-Frequency Long-Duration Anterior Thalamic Spindles
Enhancement of Hippocampal-Thalamocortical Temporal Coordination during Slow-Frequency Long-Duration Anterior Thalamic Spindles
Temporal nesting of cortical slow oscillations, thalamic spindles, and hippocampal ripples indicates multiregional neurona...
Non-Neural Factors Influencing BOLD Response Magnitudes within Individual Subjects
Non-Neural Factors Influencing BOLD Response Magnitudes within Individual Subjects
To what extent is the size of the BOLD response influenced by factors other than neural activity? In a reanalysis of three...
Oscillatory Population-Level Activity of Dorsal Raphe Serotonergic Neurons Is Inscribed in Sleep Structure
Oscillatory Population-Level Activity of Dorsal Raphe Serotonergic Neurons Is Inscribed in Sleep Structure
Dorsal raphe (DR) 5-HT neurons regulate sleep–wake transitions. Previous studies demonstrated that single-unit activity of...
Dynamics of Hierarchical Task Representations
Dynamics of Hierarchical Task Representations
Task representations are critical for cognitive control and adaptive behavior. The hierarchical organization of task repre...
Two Types of Motor Inhibition after Action Errors in Humans
Two Types of Motor Inhibition after Action Errors in Humans
Adaptive behavior requires the ability to appropriately react to action errors. Post-error slowing (PES) of response times...
Basolateral Amygdala Hyperexcitability Is Associated with Precocious Developmental Emergence of Fear-Learning in Fragile X Syndrome
Basolateral Amygdala Hyperexcitability Is Associated with Precocious Developmental Emergence of Fear-Learning in Fragile X Syndrome
Fragile X Syndrome is a neurodevelopmental disorder and the most common monogenic cause of intellectual disability, autism...
Alpha Oscillations Track Content-Specific Working Memory Capacity
Alpha Oscillations Track Content-Specific Working Memory Capacity
Although the neural basis of working memory (WM) capacity is often studied by exploiting interindividual differences, capa...
Downregulating PTBP1 Fails to Convert Astrocytes into Hippocampal Neurons and to Alleviate Symptoms in Alzheimer's Mouse Models
Downregulating PTBP1 Fails to Convert Astrocytes into Hippocampal Neurons and to Alleviate Symptoms in Alzheimer's Mouse Models
Conversion of astroglia into functional neurons has been considered a promising therapeutic strategy for neurodegenerative...
Drosophila Homolog of the Human Carpenter Syndrome Linked Gene, MEGF8, Is Required for Synapse Development and Function
Drosophila Homolog of the Human Carpenter Syndrome Linked Gene, MEGF8, Is Required for Synapse Development and Function
Drosophila multiple epidermal growth factor-like domains 8 (dMegf8) is a homolog of human MEGF8. MEGF8 encodes a multidoma...
Functional Cooperation of {alpha}-Synuclein and Tau Is Essential for Proper Corticogenesis
Functional Cooperation of {alpha}-Synuclein and Tau Is Essential for Proper Corticogenesis
Alpha-synuclein (αSyn) and tau are abundant multifunctional neuronal proteins, and their intracellular deposits have been ...
Dynamics and Mechanisms of Contrast-Dependent Modulation of Spatial-Frequency Tuning in the Early Visual Cortex
Dynamics and Mechanisms of Contrast-Dependent Modulation of Spatial-Frequency Tuning in the Early Visual Cortex
The spatial-frequency (SF) tuning of neurons in the early visual cortex is adjusted for stimulus contrast. As the contrast...
Crossed Corticostriatal Projections in the Macaque Brain
Crossed Corticostriatal Projections in the Macaque Brain
In nonhuman primates, major input to the striatum originates from ipsilateral cortex and thalamus. The striatum is a targe...