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Quantitative assessment of skin disorders induced by panitumumab: a prospective observational study
Quantitative assessment of skin disorders induced by panitumumab: a prospective observational study
Acneiform rash is frequently observed in patients undergoing cancer treatment with anti-epidermal growth factor receptor (...
Pharmacokinetic drug–drug interaction between olaparib and apixaban: a case report
Pharmacokinetic drug–drug interaction between olaparib and apixaban: a case report
Farge D, Frere C, Connors JM, Khorana A, Kakkar A, Ay C et al (2022) 2022 international clinical practice guidelines for t...
Effect of vitamin E on doxorubicin and paclitaxel-induced memory impairments in male rats
Effect of vitamin E on doxorubicin and paclitaxel-induced memory impairments in male rats
In addition to peripheral neuronal dysfunction, conventional chemotherapy can be associated with other neurological treatm...
Platinum-based chemotherapy in metastatic prostate cancer: what possibilities?
Platinum-based chemotherapy in metastatic prostate cancer: what possibilities?
Metastatic prostate cancer is a major health burden worldwide, necessitating the continuous development of effective treat...
CUDC-907 exhibits potent antitumor effects against ovarian cancer through multiple in vivo and in vitro mechanisms
CUDC-907 exhibits potent antitumor effects against ovarian cancer through multiple in vivo and in vitro mechanisms
CUDC-907 is a promising dual-target inhibitor of the HDAC and PI3K signaling pathways, with demonstrated therapeutic effec...
Relative bioavailability of fedratinib through various alternative oral administration methods in healthy adults
Relative bioavailability of fedratinib through various alternative oral administration methods in healthy adults
Fedratinib is an oral Janus kinase 2-selective inhibitor for the treatment of adult patients with intermediate-2 or high-r...
Life-threatening toxicities upon Pembrolizumab intake: could pharmacokinetics be the bad guy?
Life-threatening toxicities upon Pembrolizumab intake: could pharmacokinetics be the bad guy?
We report the case of an adult patient diagnosed with Hodgkin’s lymphoma who was scheduled for Pembrolizumab after f...
Azithromycin in cancer treatment: envisioning the probable link of mitochondrial dysfunction and necroptosis
Azithromycin in cancer treatment: envisioning the probable link of mitochondrial dysfunction and necroptosis
Zhang X, Xu H (2023) Azithromycin inhibits glioblastoma angiogenesis in mice via inducing mitochondrial dysfunction and ox...
Bidirectional pharmacokinetic drug interactions between olaparib and metformin
Bidirectional pharmacokinetic drug interactions between olaparib and metformin
Olaparib is a PARP (poly-ADP-ribose polymerase) inhibitor used for maintenance therapy in BRCA-mutated cancers. Metformin ...
Long non-coding RNAs: controversial roles in drug resistance of solid tumors mediated by autophagy
Long non-coding RNAs: controversial roles in drug resistance of solid tumors mediated by autophagy
Current genome-wide studies have indicated that a great number of long non-coding RNAs (lncRNAs) are transcribed from the ...
Polatuzumab vedotin pharmacokinetics in a hemodialysis patient with diffuse large B-cell lymphoma
Polatuzumab vedotin pharmacokinetics in a hemodialysis patient with diffuse large B-cell lymphoma
Chemotherapy for the hemodialysis (HD) patient is a challenging situation because it requires special considerations inclu...
TMEM120A-mediated regulation of chemotherapy sensitivity in colorectal cancer cells
TMEM120A-mediated regulation of chemotherapy sensitivity in colorectal cancer cells
Enhancing chemotherapy sensitivity in colorectal cancer (CRC) is critical for improving treatment outcomes. TMEM120A has b...
Pharmacokinetics and pharmacodynamics of Rh2 and aPPD ginsenosides in prostate cancer: a drug interaction perspective
Pharmacokinetics and pharmacodynamics of Rh2 and aPPD ginsenosides in prostate cancer: a drug interaction perspective
Ginsenoside Rh2 and its aglycon (aPPD) are one of the major metabolites from Panax ginseng. Preclinical studies suggest th...
Cytidine deaminase enzyme activity is a predictive biomarker in gemcitabine-treated cancer patients
Cytidine deaminase enzyme activity is a predictive biomarker in gemcitabine-treated cancer patients
Gemcitabine is a chemotherapeutic agent, widely used for the treatment of many types of cancer. Cytidine deaminas...
A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer
A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer
Capecitabine is a prodrug that converts to 5-fluorouracil (5-FU) in three steps. A previous study showed that ABCA2 rs2271...