×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Pharmacology & Pharmacy
40953
Global Medical University
6074
Allergy
1886
Anatomy & Morphology
1685
Andrology
414
Anesthesia & Intensive Care
1408
Anesthesiology
6191
Audiology & Speech-Language Pathology
358
Behavioral Sciences
111
Biochemical Research Methods
8121
Biochemistry & Molecular Biology
33909
Biodiversity Conservation
366
Biology
9836
Biophysics
10790
Biotechnology & Applied Microbiology
9649
Cardiac & Cardiovascular Systems
35094
Cardiovascular & Respiratory Systems
1644
Cell & Tissue Engineering
766
Cell Biology
12159
Chemistry, Analytical
4649
Chemistry, Applied
12712
Chemistry, Medicinal
9574
Chemistry, Multidisciplinary
20857
Clinical Immunology & Infectious Disease
483
Clinical Medicine
9629
Clinical Neurology
18330
Clinical Psychology & Psychiatry
1679
Critical Care Medicine
3652
Dentistry, Oral Surgery & Medicine
15295
Dermatology
8009
Developmental Biology
7595
Ecology
655
Education, Scientific Disciplines
2191
Emergency Medicine
4689
Endocrinology, Metabolism & Nutrition
27880
Engineering, Biomedical
4151
Entomology
482
Environmental Medicine & Public Health
5403
Evolutionary Biology
288
Gastroenterology & Hepatology
13627
General & Internal Medicine
7955
Genetics & Heredity
17150
Geriatrics & Gerontology
5617
Gerontology
366
Health Care Sciences & Services
18058
Health Policy & Services
671
Hematology
5984
Immunology
28921
Infectious Diseases
15635
Integrative & Complementary Medicine
3230
Medical Ethics
1286
Medical Informatics
2681
Medical Laboratory Technology
433
Medicine, General & Internal
49689
Medicine, Legal
591
Medicine, Research & Experimental
20731
Microbiology
26879
Mycology
0
Nanoscience & Nanotechnology
5986
Neuroimaging
1495
Neurology
5251
Neurosciences
45690
Nursing
10572
Nutrition & Dietetics
8569
Obstetrics & Gynecology
9294
Oncology
59183
Ophthalmology
11231
Optics
5219
Orthopedics
12940
Orthopedics, Rehabilitation & Sports Medicine
2050
Otolaryngology
1697
Otorhinolaryngology
5409
Parasitology
1156
Pathology
5550
Pediatrics
24158
Peripheral Vascular Disease
5258
Pharmacology/Toxicology
14139
Physiology
9836
Polymer Science
686
Primary Health Care
907
Psychiatry
23074
Psychology
5697
Psychology, Applied
113
Psychology, Biological
393
Psychology, Clinical
896
Psychology, Developmental
235
Psychology, Educational
149
Psychology, Experimental
147
Psychology, Mathematical
0
Psychology, Multidisciplinary
1697
Psychology, Psychoanalysis
41
Psychology, Social
122
Public Health & Health Care Science
2416
Public, Environmental & Occupational Health
30698
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
14064
Radiology, Nuclear Medicine & Medical Imaging
8814
Rehabilitation
3236
Remote Sensing
0
Reproductive Biology
3335
Reproductive Medicine
1340
Research/Laboratory Medicine & Medical Technology
4498
Respiratory System
8227
Rheumatology
6731
Social Sciences, Biomedical
1316
Substance Abuse
2990
Surgery
38474
Toxicology
4729
Transplantation
953
Tropical Medicine
314
Urology & Nephrology
14840
Veterinary Sciences
35
Virology
2655
Zoology
0
渠道
CANCER CHEMOTHERAPY AND PHARMACOLOGY
410
Medrxiv - Pharmacology and Therapeutics
234
AAPS JOURNAL
330
ACTA PHARMACOLOGICA SINICA
637
ADVANCED DRUG DELIVERY REVIEWS
0
ANTIVIRAL RESEARCH
0
CHEMICO-BIOLOGICAL INTERACTIONS
1112
CHEMMEDCHEM
274
CLINICAL PHARMACOKINETICS
377
CLINICAL PHARMACOLOGY & THERAPEUTICS
258
CNS DRUGS
216
CNS NEUROSCIENCE & THERAPEUTICS
116
DRUG DISCOVERY TODAY
279
DRUG METABOLISM AND DISPOSITION
464
DRUG RESISTANCE UPDATES
197
DRUG SAFETY
344
DRUGS
501
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
828
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
777
EUROPEAN JOURNAL OF PHARMACOLOGY
1811
INTERNATIONAL IMMUNOPHARMACOLOGY
3908
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2435
JOURNAL OF CONTROLLED RELEASE
1666
JOURNAL OF ETHNOPHARMACOLOGY
3020
JOURNAL OF FOOD AND DRUG ANALYSIS
157
JOURNAL OF PHARMACEUTICAL ANALYSIS
480
NATURE REVIEWS DRUG DISCOVERY
729
NEUROPHARMACOLOGY
0
NEUROPSYCHOPHARMACOLOGY
837
NEUROTOXICOLOGY
0
PHARMACOGENOMICS
28
PHARMACOLOGY & THERAPEUTICS
384
PHARMACOTHERAPY
65
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
87
TOXICOLOGY AND APPLIED PHARMACOLOGY
1
TOXICOLOGY IN VITRO
524
VALUE IN HEALTH
20
VASCULAR PHARMACOLOGY
0
ANNALS OF PHARMACOTHERAPY
130
ANTIBIOTICS-BASEL
1984
BIOMEDICAL CHROMATOGRAPHY
243
BIOPHARMACEUTICS & DRUG DISPOSITION
20
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
0
CHEMOTHERAPY
81
CHINESE MEDICINE
495
CHIRALITY
73
CLINICAL NEUROPHARMACOLOGY
64
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT
129
CLINICAL THERAPEUTICS
52
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
55
DOSE-RESPONSE
78
DRUG DEVELOPMENT RESEARCH
121
EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE
325
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
838
HUMAN & EXPERIMENTAL TOXICOLOGY
105
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
0
INTERNATIONAL JOURNAL OF TOXICOLOGY
36
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
172
JOURNAL OF ANTIBIOTICS
324
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
430
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
30
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
170
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
2335
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
505
JOURNAL OF ONCOLOGY PHARMACY PRACTICE
176
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
0
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
0
JOURNAL OF PHARMACOLOGICAL SCIENCES
0
JOURNAL OF PHARMACY AND PHARMACOLOGY
18
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
805
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
121
PHARMACOGENOMICS & PERSONALIZED MEDICINE
300
PHARMACOLOGY
125
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
0
SKIN PHARMACOLOGY AND PHYSIOLOGY
70
THERAPEUTIC ADVANCES IN DRUG SAFETY
22
THERAPEUTIC DRUG MONITORING
181
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
51
INDIAN JOURNAL OF PHARMACOLOGY
16
JOURNAL OF APPLIED BIOMEDICINE
44
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
47
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
381
THERAPIE
368
SCIENTIA PHARMACEUTICA
108
ADMET AND DMPK
96
ADVANCED THERAPEUTICS
95
ADVANCES IN PHARMACOLOGY AND PHARMACY
115
ADVANCES IN TRADITIONAL MEDICINE
19
ASIAN JOURNAL OF PHARMACEUTICAL RESEARCH AND HEALTH CARE
26
ASIAN JOURNAL OF PHARMACEUTICS
190
CANADIAN JOURNAL OF HOSPITAL PHARMACY
223
CURRENT DRUG THERAPY
28
EGYPTIAN PHARMACEUTICAL JOURNAL
42
FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES
361
GABI JOURNAL-GENERICS AND BIOSIMILARS INITIATIVE JOURNAL
67
INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION
212
JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH
164
JOURNAL OF ANAESTHESIOLOGY CLINICAL PHARMACOLOGY
29
JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES
150
JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE
302
JOURNAL OF PHARMACOLOGY & PHARMACOTHERAPEUTICS
44
JOURNAL OF PHARMACY AND BIOALLIED SCIENCES
39
JOURNAL OF PHARMACY PRACTICE
98
JOURNAL OF RESEARCH IN PHARMACY PRACTICE
40
RESEARCH JOURNAL OF PHARMACOGNOSY
111
PHARMACEUTICAL MEDICINE
62
PHARMACIA
154
PHARMACOECONOMICS-OPEN
254
PHARMACY
176
PHARMACY PRACTICE-GRANADA
31
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
126
DRUGS & AGING
256
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
561
INVESTIGATIONAL NEW DRUGS
325
JOURNAL OF PHARMACEUTICAL INNOVATION
359
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
165
NEUROTHERAPEUTICS
355
PEDIATRIC DRUGS
192
THERAPEUTIC INNOVATION & REGULATORY SCIENCE
352
SCI时时刷
search
全部
推荐
+
Ferroptosis – a potential feature underlying neratinib-induced colonic epithelial injury
Neratinib, a small-molecule tyrosine kinase inhibitor (TKI) that irreversibly binds to human epidermal growth factor recep...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
A sub-pharmacological test dose does not predict individual docetaxel exposure in prostate cancer patients
Docetaxel is a cytotoxic drug used for first-line treatment of various malignancies. It has a narrow therapeutic index and...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Aclarubicin: contemporary insights into its mechanism of action, toxicity, pharmacokinetics, and clinical standing
Aclarubicin (aclacinomycin A) is one of the anthracycline antineoplastic antibiotics with a multifaceted mechanism of anti...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Regorafenib plus FOLFIRINOX as first-line treatment for patients with RAS-mutant metastatic colorectal cancer (FOLFIRINOX-R trial): a dose-escalation study
The combination of bevacizumab and FOLFIRINOX is used in patients with RAS-mutant metastatic colorectal cancer (RASm-mCRC)...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure–response relationships: a proof-of-concept study with alectinib
In exposure–response analyses of oral targeted anticancer agents, longitudinal plasma trough concentrations are ofte...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Systematic review: genetic polymorphisms in the pharmacokinetics of high-dose methotrexate in pediatric acute lymphoblastic leukemia patients
Variations in pharmacokinetic responses to high-dose methotrexate are essential for the prognosis and management of toxici...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Role of renin angiotensin system inhibitors and metformin in Glioblastoma Therapy: a review
Glioblastoma multiforme (GBM) is a highly aggressive and incurable disease accounting for about 10,000 deaths in the USA e...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Quantitative characterization of the effects of fulvestrant alone or in combination with taselisib (PI3Kinase inhibitor) on longitudinal tumor growth in patients with estrogen receptor-positive, HER2-negative, PIK3CA-mutant, advanced or metastatic breast cancer
Among cases of breast cancer, estrogen receptor-positive (ER +), PIK3CA-mutant, HER2- advanced breast cancer stands ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Immunoregulatory cyclophilin a improves low-dose chemotherapy with a modulation of the immune tumor microenvironment in experimental models of melanoma B16 and lymphoma EL4 in vivo
Different regimens of low-dose chemotherapy (LDC) are currently being actively developed and introduced into clinical prac...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Alterations in pharmacogenetic genes and their implications for imatinib resistance in Chronic Myeloid Leukemia patients from an admixed population
Imatinib is the tyrosine kinase inhibitor used as the gold standard for the treatment of Chronic Myeloid Leukemia. However...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Development of a novel nomogram for predicting delayed methotrexate excretion following high-dose methotrexate in adult patients with hematologic malignancies
High-dose methotrexate (HDMTX) is integral in treating hematologic malignancies but carries risks of severe toxicities due...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
AKR1C4 regulates the sensitivity of colorectal cancer cells to chemotherapy through ferroptosis modulation
Colorectal cancer (CRC) remains a major global health concern, necessitating innovative therapeutic strategies to enhance ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Evaluation of the effect of modafinil on the pharmacokinetics of encorafenib and binimetinib in patients with BRAF V600-mutant advanced solid tumors
A clinical drug-drug interaction (DDI) study was designed to evaluate the effect of multiple doses of modafinil, a moderat...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Population pharmacokinetics of TLD-1, a novel liposomal doxorubicin, in a phase I trial
TLD-1 is a novel pegylated liposomal doxorubicin (PLD) formulation aiming to optimise the PLD efficacy-toxicity ratio. We ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies
The purpose of this study was to analyze potential differences in antitumor efficacy and pharmacokinetics between intraven...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
ZNF384 transcriptionally activated MGST1 to confer TMZ resistance of glioma cells by negatively regulating ferroptosis
Drug resistance is one of the major reasons of the poor prognosis and recurs frequently in glioma. Ferroptosis is consider...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Pre-treatment amino acids and risk of paclitaxel-induced peripheral neuropathy in SWOG S0221
Chemotherapy-induced peripheral neuropathy (CIPN) is a treatment-limiting and debilitating neurotoxicity of many commonly ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Oral docetaxel plus encequidar – a phase 1 clinical trial
To determine the bioavailability, safety, and tolerability of a single dose of oral docetaxel plus encequidar (oDox ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Physiologically-based pharmacokinetic models versus allometric scaling for prediction of tyrosine-kinase inhibitor exposure from adults to children
Model-based methods can predict pediatric exposure and support initial dose selection. The aim of this study was to evalua...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Overexposure to venetoclax is associated with prolonged-duration of neutropenia during venetoclax and azacitidine therapy in Japanese patients with acute myeloid leukemia
An observational study was conducted to evaluate the pharmacokinetics of venetoclax and its impact on the efficacy and saf...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Using maximum plasma concentration (Cmax) to personalize taxane treatment and reduce toxicity
Taxanes are a widely used class of anticancer agents that play a vital role in the treatment of a variety of cancers. Howe...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice
The Ataxia Telangiectasia and Rad3-related (ATR) protein complex is an apical initiator of DNA damage response pathways. S...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Effect of food on the pharmacokinetics and safety profiles of a new PARP inhibitor fuzuloparib capsules in healthy volunteers
This study assessed effect of food on pharmacokinetics (PK) and safety of fuzuloparib capsules. A randomized, open-label, ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Combined treatment of All-trans retinoic acid with Tamoxifen suppresses ovarian cancer
Ovarian cancer is a malignant tumor of the female reproductive system, and its mortality rate is as high as 70%. Estrogen ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Gene polymorphisms of TACR1 serve as the potential pharmacogenetic predictors of response to the neurokinin-1 receptor antagonist-based antiemetic regimens: a candidate-gene association study in breast cancer patients
The current candidate gene association study aims to investigate tag SNPs from the TACR1 gene as pharmacogenetic predictor...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Preventive effect of free radical scavenger edaravone lotion on cyclophosphamide chemotherapy-induced alopecia
We investigated the inhibitory effect of edaravone (EDR) lotion on chemotherapy-induced alopecia (CIA) to improve the qual...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Pharmacokinetic study of capivasertib and the CYP3A4 substrate midazolam in patients with advanced solid tumors
Capivasertib, a potent, selective inhibitor of all three AKT serine/threonine kinase (AKT) isoforms, is being evaluated in...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
PARP1 promotes EGFR-TKI drug-resistance via PI3K/AKT pathway in non-small-cell lung cancer
Tyrosine kinase inhibitor (TKI) resistance is the main type of drug resistance in lung cancer patients with epidermal grow...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
Prognostic impact of concomitant pH-regulating drugs in patients with non-small cell lung cancer receiving epidermal growth factor receptor tyrosine kinase inhibitors: the Tokushukai REAl-world Data project 01-S1
This study aimed to examine the prognostic impact of concomitant pH-regulating drug use in patients with epidermal growth ...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro
Polo-like kinase 1 (PLK1) is a critical therapeutic target in the treatment of head and neck squamous cell carcinoma (HNSC...
Cancer Chemotherapy And Pharmacology
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin