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New approaches to secondary metabolite discovery from anaerobic gut microbes
New approaches to secondary metabolite discovery from anaerobic gut microbes
The animal gut microbiome is a complex system of diverse, predominantly anaerobic microbiota with secondary metabolite pot...
A Lambda-evo (λevo) phage platform for Zika virus EDIII protein display
A Lambda-evo (λevo) phage platform for Zika virus EDIII protein display
One of the most significant bacteriophage technologies is phage display, in which heterologous peptides are exhibited on t...
Estimation of PHA concentrations from cell density data in Cupriavidus necator
Estimation of PHA concentrations from cell density data in Cupriavidus necator
The production of biodegradable and biobased polymers is one way to overcome the present plastic pollution while using che...
Effects of gut microbiota and metabolites on the host defense peptide expression
Effects of gut microbiota and metabolites on the host defense peptide expression
The widespread use of antibiotics has led to the emergence of multidrug-resistant bacteria, which pose significant threats...
Microaerobic biodegradation of aromatic hydrocarbon mixtures: strategies for efficient nitrate and oxygen dosage
Microaerobic biodegradation of aromatic hydrocarbon mixtures: strategies for efficient nitrate and oxygen dosage
The biodegradation of organic aromatic compounds in subsurface environments is often hindered by limited dissolved oxygen....
Exploring Tetraselmis chui microbiomes—functional metagenomics for novel catalases and superoxide dismutases
Exploring Tetraselmis chui microbiomes—functional metagenomics for novel catalases and superoxide dismutases
The focus on microalgae for applications in several fields, e.g. resources for biofuel, the food industry, cosmetics, nutr...
Characterization and design of dipeptide media formulation for scalable therapeutic production
Characterization and design of dipeptide media formulation for scalable therapeutic production
Process intensification and simplification in biopharmaceutical manufacturing have driven the exploration of advanced feed...
Evaluation of MALDI-TOF for identification of Vibrio cholerae and Vibrio parahaemolyticus from growth on agar media
Evaluation of MALDI-TOF for identification of Vibrio cholerae and Vibrio parahaemolyticus from growth on agar media
Two methods were compared for their ability to accurately identify Vibrio species of interest: whole genome sequencing as ...
Anxiety of microbially synthesized Fe3O4-SPIONs on embryonic/larval ontogeny in red tilapia (Oreochromis sp.)
Anxiety of microbially synthesized Fe3O4-SPIONs on embryonic/larval ontogeny in red tilapia (Oreochromis sp.)
Iron oxide nanoparticles, recognized for their superparamagnetic properties, are promising for future healthcare therapies...
Identification and monitoring of cell heterogeneity from plasmid recombination during limonene production
Identification and monitoring of cell heterogeneity from plasmid recombination during limonene production
Detecting alterations in plasmid structures is often performed using conventional molecular biology. However, these method...
Precision tumor treatment utilizing bacteria: principles and future perspectives
Precision tumor treatment utilizing bacteria: principles and future perspectives
Bacteria-based tumor therapy, which releases therapeutic payloads or remodels the tumor’s immune-suppressive microen...
Targeted knockdown of ATM, ATR, and PDEδ increases Gag HIV-1 VLP production in HEK293 cells
Targeted knockdown of ATM, ATR, and PDEδ increases Gag HIV-1 VLP production in HEK293 cells
Several strategies have been developed in recent years to improve virus-like particle (VLP)-based vaccine production proce...
Trans-nuclei CRISPR/Cas9: safe approach for genome editing in the edible mushroom excluding foreign DNA sequences
Trans-nuclei CRISPR/Cas9: safe approach for genome editing in the edible mushroom excluding foreign DNA sequences
Clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9)-assisted genome editi...
Maize drought protection by Azospirillum argentinense Az19 requires bacterial trehalose accumulation
Maize drought protection by Azospirillum argentinense Az19 requires bacterial trehalose accumulation
Azospirillum argentinense Az19 is an osmotolerant plant growth-promoting bacterium that protects maize plants from drought...
Holistic monitoring of Campylobacter jejuni biofilms with NanoLuc bioluminescence
Holistic monitoring of Campylobacter jejuni biofilms with NanoLuc bioluminescence
Campylobacter jejuni, a major cause of foodborne zoonotic infections worldwide, shows a paradoxical ability to survive des...
Omics-driven onboarding of the carotenoid producing red yeast Xanthophyllomyces dendrorhous CBS 6938
Omics-driven onboarding of the carotenoid producing red yeast Xanthophyllomyces dendrorhous CBS 6938
Transcriptomics is a powerful approach for functional genomics and systems biology, yet it can also be used for genetic pa...
Substrate expansion of Geotrichum candidum alcohol dehydrogenase towards diaryl ketones by mutation
Substrate expansion of Geotrichum candidum alcohol dehydrogenase towards diaryl ketones by mutation
Chiral diaryl alcohols, such as (4-chlorophenyl)(pyridin-2-yl)methanol, are important intermediates for pharmaceutical syn...
Novel isothermal nucleic acid amplification method for detecting malaria parasites
Novel isothermal nucleic acid amplification method for detecting malaria parasites
Malaria, a parasitic disease caused by Plasmodium spp. and transmitted by Anopheles mosquitoes, remains a major global hea...
Phormidium versicolor PC skin cream evaluation for its stability and biological activities
Phormidium versicolor PC skin cream evaluation for its stability and biological activities
In the present investigation, 13% ± 0.84 of the extracted and purified phycocyanin from Phormidium versic...
Production of virus-like particles of FMDV by 3C protease cleaving precursor polyprotein P1 in vitro
Production of virus-like particles of FMDV by 3C protease cleaving precursor polyprotein P1 in vitro
Nonstructural protein 3C, a master protease of Picornaviridae, plays a critical role in viral replication by directly clea...
Genomic characteristics and genetic manipulation of the marine yeast Scheffersomyces spartinae
Genomic characteristics and genetic manipulation of the marine yeast Scheffersomyces spartinae
The halotolerant yeast Scheffersomyces spartinae, commonly found in marine environments, holds significant potential for v...
Integration of metabolomics and other omics: from microbes to microbiome
Integration of metabolomics and other omics: from microbes to microbiome
Metabolomics is a cutting-edge omics technology that identifies metabolites in organisms and their environments and tracks...
Understanding microbial syngas fermentation rates
Understanding microbial syngas fermentation rates
Syngas fermentation to ethanol has reached industrial production. Further improvement of this process would be aided by qu...
Improved recombinant expression of soluble cathepsin B and L in Escherichia coli
Improved recombinant expression of soluble cathepsin B and L in Escherichia coli
Cysteine cathepsins such as cathepsin B and L play an important role in numerous diseases like acute pancreatitis or SARS-...
Quantitative fluorescent detection of tetracycline in animal-derived foods using quantum dots
Quantitative fluorescent detection of tetracycline in animal-derived foods using quantum dots
Tetracycline (Tc) antibiotics, a class of synthetically produced broad-spectrum antimicrobial drugs, have been widely used...
Metabolic mechanism of lignin-derived aromatics in white-rot fungi
Metabolic mechanism of lignin-derived aromatics in white-rot fungi
White-rot fungi, such as Phanerochaete chrysosporium, play a crucial role in biodegrading lignocellulosic biomass includin...
Oral microbiota in preschoolers with rampant caries: a matched case–control study
Oral microbiota in preschoolers with rampant caries: a matched case–control study
Rampant caries is identified by rapid onset, severe decay affecting multiple surfaces, and early pulp infection. This case...
Coelimycin inside out — negative feedback regulation by its intracellular precursors
Coelimycin inside out — negative feedback regulation by its intracellular precursors
Coelimycin (CPK) producer Streptomyces coelicolor A3(2) is a well-established model for the genetic studies of bacteria fr...
Unforeseen current and future benefits of uncommon yeast: the Metschnikowia genus
Unforeseen current and future benefits of uncommon yeast: the Metschnikowia genus
Metschnikowia, the single-cell yeast form, is a genus of 85 species in the Saccharomycetales order that developed in both ...