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Rapid Assessment of the Need for Evidence: Applying the Principles of Value of Information to Research Prioritisation
Rapid Assessment of the Need for Evidence: Applying the Principles of Value of Information to Research Prioritisation
We propose a short-cut heuristic approach to rapidly estimate value of information (VOI) using information commonly report...
Evaluating the Cost-Utility of Continuous Glucose Monitoring in Individuals with Type 1 Diabetes: A Systematic Review of the Methods and Quality of Studies Using Decision Models or Empirical Data
Evaluating the Cost-Utility of Continuous Glucose Monitoring in Individuals with Type 1 Diabetes: A Systematic Review of the Methods and Quality of Studies Using Decision Models or Empirical Data
This review presents a critical appraisal of differences in the methodologies and quality of model-based and empirical dat...
A Systematic Review of Methods for Estimating Productivity Losses due to Illness or Caregiving in Low- and Middle-Income Countries
A Systematic Review of Methods for Estimating Productivity Losses due to Illness or Caregiving in Low- and Middle-Income Countries
Productivity losses are often included in costing studies and economic evaluations to provide a comprehensive understandin...
A Systematic Review of Methods and Practice for Integrating Maternal, Fetal, and Child Health Outcomes, and Family Spillover Effects into Cost-Utility Analyses
A Systematic Review of Methods and Practice for Integrating Maternal, Fetal, and Child Health Outcomes, and Family Spillover Effects into Cost-Utility Analyses
Maternal-perinatal interventions delivered during pregnancy or childbirth have unique characteristics that impact the heal...
A Model-Based Economic Evaluation of Hypothetical Treatments for Amyotrophic Lateral Sclerosis in the UK: Implications for Pricing of New and Emerging Health Technologies
A Model-Based Economic Evaluation of Hypothetical Treatments for Amyotrophic Lateral Sclerosis in the UK: Implications for Pricing of New and Emerging Health Technologies
Amyotrophic lateral sclerosis (ALS) is a devastating disease which leads to loss of muscle function and paralysis. Histori...
Comparing Generic Paediatric Health-Related Quality-of-Life Instruments: A Dimensionality Assessment Using Factor Analysis
Comparing Generic Paediatric Health-Related Quality-of-Life Instruments: A Dimensionality Assessment Using Factor Analysis
Widely used generic instruments to measure paediatric health-related quality of life (HRQoL) include the EQ-5D-Y-5L, Child...
Examining the Effect of Depicting a Patient Affected by a Negative Reimbursement Decision in Healthcare on Public Disagreement with the Decision
Examining the Effect of Depicting a Patient Affected by a Negative Reimbursement Decision in Healthcare on Public Disagreement with the Decision
The availability of increasingly advanced and expensive new health technologies puts considerable pressure on publicly fin...
Cost Effectiveness of Fremanezumab in Episodic and Chronic Migraine Patients from a Japanese Healthcare Perspective
Cost Effectiveness of Fremanezumab in Episodic and Chronic Migraine Patients from a Japanese Healthcare Perspective
Fremanezumab is an effective treatment for episodic (EM) and chronic migraine (CM) patients in Japan, but its cost effecti...
Bayesian Meta-Analysis of Health State Utility Values: A Tutorial with a Practical Application in Heart Failure
Bayesian Meta-Analysis of Health State Utility Values: A Tutorial with a Practical Application in Heart Failure
Researchers incorporate health state utility values as inputs to inform economic models. However, for a particular health ...
A Prototype Software Framework for Transferable Computational Health Economic Models and Its Early Application in Youth Mental Health
A Prototype Software Framework for Transferable Computational Health Economic Models and Its Early Application in Youth Mental Health
Summary: We are developing an economic model to explore multiple topics in Australian youth mental health policy. To help ...
Cost-of-Illness of Skin Cancer: A Systematic Review
Cost-of-Illness of Skin Cancer: A Systematic Review
Skin cancer’s rising incidence demands understanding of its economic impact. The current understanding is fragmented...
Estimating and Rewarding the Value of Healthcare Interventions Beyond the Healthcare Sector: A Conceptual Framework
Estimating and Rewarding the Value of Healthcare Interventions Beyond the Healthcare Sector: A Conceptual Framework
Evaluating healthcare interventions for their impacts beyond health outcomes may result in recognition of changes in human...
A Comparison of the Psychometric Properties of the EQ-5D-Y-3L and EQ-5D-Y-5L Using Paediatric Multi-Instrument Comparison (P-MIC) Study Data
A Comparison of the Psychometric Properties of the EQ-5D-Y-3L and EQ-5D-Y-5L Using Paediatric Multi-Instrument Comparison (P-MIC) Study Data
The EQ-5D-Y is a generic health-related quality of life (HRQoL) measure suitable for children and adolescents. There are t...
Lessons Learned from Model-based Economic Evaluations of COVID-19 Drug Treatments Under Pandemic Circumstances: Results from a Systematic Review
Lessons Learned from Model-based Economic Evaluations of COVID-19 Drug Treatments Under Pandemic Circumstances: Results from a Systematic Review
Following clinical research of potential coronavirus disease 2019 (COVID-19) treatments, numerous decision–analytic ...
Cost-Effectiveness of Lovotibeglogene Autotemcel (Lovo-Cel) Gene Therapy for Patients with Sickle Cell Disease and Recurrent Vaso-Occlusive Events in the United States
Cost-Effectiveness of Lovotibeglogene Autotemcel (Lovo-Cel) Gene Therapy for Patients with Sickle Cell Disease and Recurrent Vaso-Occlusive Events in the United States
Gene therapies for sickle cell disease (SCD) may offer meaningful benefits for patients and society. This study evaluated ...
Advances in Addressing Patient Heterogeneity in Economic Evaluation: A Review of the Methods Literature
Advances in Addressing Patient Heterogeneity in Economic Evaluation: A Review of the Methods Literature
Cost-effectiveness analyses commonly use population or sample averages, which can mask key differences across subgroups an...
A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations
A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations
The current use of health economic decision models in HTA is mostly confined to single use cases, which may be inefficient...
Issues, Challenges and Opportunities for Economic Evaluations of Orphan Drugs in Rare Diseases: An Umbrella Review
Issues, Challenges and Opportunities for Economic Evaluations of Orphan Drugs in Rare Diseases: An Umbrella Review
There are significant challenges when obtaining clinical and economic evidence for health technology assessments of rare d...
Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Decision models for health technology assessment (HTA) are largely submitted to HTA agencies using commercial software, wh...
Value of Information for Clinical Trial Design: The Importance of Considering All Relevant Comparators
Value of Information for Clinical Trial Design: The Importance of Considering All Relevant Comparators
Value of Information (VOI) analyses calculate the economic value that could be generated by obtaining further information ...
Is Risk-Stratifying Patients with Colorectal Cancer Using a Deep Learning-Based Prognostic Biomarker Cost-Effective?
Is Risk-Stratifying Patients with Colorectal Cancer Using a Deep Learning-Based Prognostic Biomarker Cost-Effective?
Accurate risk stratification of patients with stage II and III colorectal cancer (CRC) prior to treatment selecti...
Childhood Transitions Between Weight Status Categories: Evidence from the UK Millennium Cohort Study
Childhood Transitions Between Weight Status Categories: Evidence from the UK Millennium Cohort Study
Assessing the cost-effectiveness of interventions targeting childhood excess weight requires estimates of the hazards of t...
Challenges and Opportunities in Interdisciplinary Research and Real-World Data for Treatment Sequences in Health Technology Assessments
Challenges and Opportunities in Interdisciplinary Research and Real-World Data for Treatment Sequences in Health Technology Assessments
With an ever-increasing number of treatment options, the assessment of treatment sequences has become crucial in health te...
Developing a Program Costs Checklist of Digital Health Interventions: A Scoping Review and Empirical Case Study
Developing a Program Costs Checklist of Digital Health Interventions: A Scoping Review and Empirical Case Study
The rate of development and complexity of digital health interventions (DHIs) in recent years has to some extent outpaced ...
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations
The increasing number of studies that generate health state utility values (HSUVs) and the impact of HSUVs on cost-utility...
Critical Examination of Modeling Approaches Used in Economic Evaluations of First-Line Treatments for Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: A Systematic Literature Review
Critical Examination of Modeling Approaches Used in Economic Evaluations of First-Line Treatments for Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: A Systematic Literature Review
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with up to 32% of patients with NSCLC harboring...
Understanding Clinician Preferences for Treatment Attributes in Oncology: A Discrete Choice Experiment of Oncologists’ and Urologists’ Preferences for First-Line Treatment of Locally Advanced/Unresectable Metastatic Urothelial Carcinoma in Five European Countries
Understanding Clinician Preferences for Treatment Attributes in Oncology: A Discrete Choice Experiment of Oncologists’ and Urologists’ Preferences for First-Line Treatment of Locally Advanced/Unresectable Metastatic Urothelial Carcinoma in Five European Countries
Prior discrete choice experiments (DCE) in oncology found that, on average, clinicians rank survival as the most important...
Economic Evaluations of Treatments for Duchenne Muscular Dystrophy: The Caregiver QALY Trap
Economic Evaluations of Treatments for Duchenne Muscular Dystrophy: The Caregiver QALY Trap
Adelman RD, Tmanova LL, Delgado D, Dion S, Lachs MS. Caregiver burden: a clinical review. JAMA. 2014;311:1052–60.Article  ...
Population Norms for the EQ-5D-5L, PROPr and SF-6D in Hungary
Population Norms for the EQ-5D-5L, PROPr and SF-6D in Hungary
This study aimed to develop population norms for three preference-accompanied measures [EQ-5D-5L, Patient-Reported Outcome...
Exploring the Use of Pictorial Approaches in the Development of Paediatric Patient-Reported Outcome Instruments: A Systematic Review
Exploring the Use of Pictorial Approaches in the Development of Paediatric Patient-Reported Outcome Instruments: A Systematic Review
Children may find self-reporting health-related quality of life (HRQoL) using patient-reported outcome measures (PROMs) pr...
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