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A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations
A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations
The current use of health economic decision models in HTA is mostly confined to single use cases, which may be inefficient...
Issues, Challenges and Opportunities for Economic Evaluations of Orphan Drugs in Rare Diseases: An Umbrella Review
Issues, Challenges and Opportunities for Economic Evaluations of Orphan Drugs in Rare Diseases: An Umbrella Review
There are significant challenges when obtaining clinical and economic evidence for health technology assessments of rare d...
Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Decision models for health technology assessment (HTA) are largely submitted to HTA agencies using commercial software, wh...
Value of Information for Clinical Trial Design: The Importance of Considering All Relevant Comparators
Value of Information for Clinical Trial Design: The Importance of Considering All Relevant Comparators
Value of Information (VOI) analyses calculate the economic value that could be generated by obtaining further information ...
Is Risk-Stratifying Patients with Colorectal Cancer Using a Deep Learning-Based Prognostic Biomarker Cost-Effective?
Is Risk-Stratifying Patients with Colorectal Cancer Using a Deep Learning-Based Prognostic Biomarker Cost-Effective?
Accurate risk stratification of patients with stage II and III colorectal cancer (CRC) prior to treatment selecti...
Childhood Transitions Between Weight Status Categories: Evidence from the UK Millennium Cohort Study
Childhood Transitions Between Weight Status Categories: Evidence from the UK Millennium Cohort Study
Assessing the cost-effectiveness of interventions targeting childhood excess weight requires estimates of the hazards of t...
Challenges and Opportunities in Interdisciplinary Research and Real-World Data for Treatment Sequences in Health Technology Assessments
Challenges and Opportunities in Interdisciplinary Research and Real-World Data for Treatment Sequences in Health Technology Assessments
With an ever-increasing number of treatment options, the assessment of treatment sequences has become crucial in health te...
Developing a Program Costs Checklist of Digital Health Interventions: A Scoping Review and Empirical Case Study
Developing a Program Costs Checklist of Digital Health Interventions: A Scoping Review and Empirical Case Study
The rate of development and complexity of digital health interventions (DHIs) in recent years has to some extent outpaced ...
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations
The increasing number of studies that generate health state utility values (HSUVs) and the impact of HSUVs on cost-utility...
Critical Examination of Modeling Approaches Used in Economic Evaluations of First-Line Treatments for Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: A Systematic Literature Review
Critical Examination of Modeling Approaches Used in Economic Evaluations of First-Line Treatments for Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: A Systematic Literature Review
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with up to 32% of patients with NSCLC harboring...
Understanding Clinician Preferences for Treatment Attributes in Oncology: A Discrete Choice Experiment of Oncologists’ and Urologists’ Preferences for First-Line Treatment of Locally Advanced/Unresectable Metastatic Urothelial Carcinoma in Five European Countries
Understanding Clinician Preferences for Treatment Attributes in Oncology: A Discrete Choice Experiment of Oncologists’ and Urologists’ Preferences for First-Line Treatment of Locally Advanced/Unresectable Metastatic Urothelial Carcinoma in Five European Countries
Prior discrete choice experiments (DCE) in oncology found that, on average, clinicians rank survival as the most important...
Economic Evaluations of Treatments for Duchenne Muscular Dystrophy: The Caregiver QALY Trap
Economic Evaluations of Treatments for Duchenne Muscular Dystrophy: The Caregiver QALY Trap
Adelman RD, Tmanova LL, Delgado D, Dion S, Lachs MS. Caregiver burden: a clinical review. JAMA. 2014;311:1052–60.Article  ...
Population Norms for the EQ-5D-5L, PROPr and SF-6D in Hungary
Population Norms for the EQ-5D-5L, PROPr and SF-6D in Hungary
This study aimed to develop population norms for three preference-accompanied measures [EQ-5D-5L, Patient-Reported Outcome...
Exploring the Use of Pictorial Approaches in the Development of Paediatric Patient-Reported Outcome Instruments: A Systematic Review
Exploring the Use of Pictorial Approaches in the Development of Paediatric Patient-Reported Outcome Instruments: A Systematic Review
Children may find self-reporting health-related quality of life (HRQoL) using patient-reported outcome measures (PROMs) pr...
Content Comparison of Quality-of-Life Instruments Used in Economic Evaluations of Sleep Disorder Interventions: A Systematic Review
Content Comparison of Quality-of-Life Instruments Used in Economic Evaluations of Sleep Disorder Interventions: A Systematic Review
Assessment of quality of life (QoL) in people living with sleep disorders using questionnaires is necessary to compare int...
Incorporating Real Option Value in Valuing Innovation: A Way Forward
Incorporating Real Option Value in Valuing Innovation: A Way Forward
Considerable progress has been made in defining and measuring the real option value (ROV) of medical technologies. However...
Budget Impact of Introducing Fixed-Duration Mosunetuzumab for the Treatment of Relapsed or Refractory Follicular Lymphoma After Two or More Lines of Systemic Therapy in the USA
Budget Impact of Introducing Fixed-Duration Mosunetuzumab for the Treatment of Relapsed or Refractory Follicular Lymphoma After Two or More Lines of Systemic Therapy in the USA
This study aimed to assess the budget impact of introducing fixed-duration mosunetuzumab as a treatment option for adult p...
Psychometric Properties of Child Health Utility 9D (CHU9D) Proxy Version Administered to Parents and Caregivers of Children Aged 2–4 Years Compared with Pediatric Quality of Life Inventory™ (PedsQL)
Psychometric Properties of Child Health Utility 9D (CHU9D) Proxy Version Administered to Parents and Caregivers of Children Aged 2–4 Years Compared with Pediatric Quality of Life Inventory™ (PedsQL)
This study examines the psychometric properties of the Child Health Utility 9D (CHU9D) proxy version administered to paren...
An Investigation of Inter-Rater and Intra-Proxy Agreement in Measuring Quality of Life of Children in the Community Using the EQ-5D-Y-3L
An Investigation of Inter-Rater and Intra-Proxy Agreement in Measuring Quality of Life of Children in the Community Using the EQ-5D-Y-3L
Self-reporting of health-related quality of life (HRQoL) in children is not always feasible. To date, proxy perspectives (...
Transporting Comparative Effectiveness Evidence Between Countries: Considerations for Health Technology Assessments
Transporting Comparative Effectiveness Evidence Between Countries: Considerations for Health Technology Assessments
Internal validity is often the primary concern for health technology assessment agencies when assessing comparative effect...
Cost-Effectiveness Analysis of Vaccines for COVID-19 According to Sex, Comorbidity and Socioeconomic Status: A Population Study
Cost-Effectiveness Analysis of Vaccines for COVID-19 According to Sex, Comorbidity and Socioeconomic Status: A Population Study
Coronavirus disease 2019 (COVID-19) vaccines are extremely effective in preventing severe disease, but their real-world co...
The Burden of Type 2 Diabetes on the Productivity and Economy in Sub-Saharan Africa: A Life Table Modelling Analysis from a South African Perspective
The Burden of Type 2 Diabetes on the Productivity and Economy in Sub-Saharan Africa: A Life Table Modelling Analysis from a South African Perspective
The prevalence of type 2 diabetes (T2D) is rapidly increasing in Sub-Saharan Africa (SSA). T2D increases the risk of prema...
Cost-effectiveness of Cabotegravir Long-Acting for HIV Pre-exposure Prophylaxis in the United States
Cost-effectiveness of Cabotegravir Long-Acting for HIV Pre-exposure Prophylaxis in the United States
Cabotegravir long-acting (CAB–LA) administered every 2 months was approved in the USA as pre-exposure prophylaxis (P...
Cost-Effectiveness of Screening Strategies for Familial Hypercholesterolaemia: An Updated Systematic Review
Cost-Effectiveness of Screening Strategies for Familial Hypercholesterolaemia: An Updated Systematic Review
This study aimed to systematically synthesise the cost-effectiveness of screening strategies to detect heterozygous famili...
Making Decision Models Fit for Purpose: The Importance of Ensuring Stakeholder Involvement
Making Decision Models Fit for Purpose: The Importance of Ensuring Stakeholder Involvement
Canada’s Drug and Health Technology Agency. Guidelines for the Economic Evaluation of Health Technologies: Canada—4th Edit...
Psychometric Performance Comparison of the Adapted versus Original Versions of the EQ-5D-Y-3L and -Y-5L in Proxy Respondents for 2- to 4-Year-Olds
Psychometric Performance Comparison of the Adapted versus Original Versions of the EQ-5D-Y-3L and -Y-5L in Proxy Respondents for 2- to 4-Year-Olds
Few preference-weighted instruments are available to measure health-related quality of life in young children (2–4&a...
The Validity of the EuroQol Health and Wellbeing Short Version (EQ-HWB-S) Instrument in Parents of Children With and Without Health Conditions
The Validity of the EuroQol Health and Wellbeing Short Version (EQ-HWB-S) Instrument in Parents of Children With and Without Health Conditions
 The EuroQol Health and Wellbeing Short Version (EQ-HWB-S) instrument has been developed to measure the health an...
The RETRIEVE Checklist for Studies Reporting the Elicitation of Stated Preferences for Child Health-Related Quality of Life
The RETRIEVE Checklist for Studies Reporting the Elicitation of Stated Preferences for Child Health-Related Quality of Life
Recent systematic reviews show varying methods for eliciting, modelling, and reporting preference-based values for child h...
Exploring the Cost Effectiveness of a Whole-Genome Sequencing-Based Biomarker for Treatment Selection in Patients with Advanced Lung Cancer Ineligible for Targeted Therapy
Exploring the Cost Effectiveness of a Whole-Genome Sequencing-Based Biomarker for Treatment Selection in Patients with Advanced Lung Cancer Ineligible for Targeted Therapy
We aimed to perform an early cost-effectiveness analysis of using a whole-genome sequencing-based tumor mutation burden (W...
Cost Effectiveness of Zanubrutinib Versus Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
Cost Effectiveness of Zanubrutinib Versus Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
While the efficacy and safety of zanubrutinib have been established in relapsed or refractory chronic lymphocytic leukemia...
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