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Investigating the effect of using a home safety training application by caregivers on accident risk management in the elderly
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Association of the interaction between daily step counts and frailty with disability in older adults
Association of the interaction between daily step counts and frailty with disability in older adults
The differences in the association of objectively measured physical activity with disability between frail and non-frail o...
Linking metabolic syndrome, cerebral small vessel disease, and cognitive health: insights from a subclinical population study using TriNetX
Linking metabolic syndrome, cerebral small vessel disease, and cognitive health: insights from a subclinical population study using TriNetX
Metabolic syndrome (MetS) has been linked to accelerated cognitive decline and Alzheimer’s disease and related demen...
A unique inflammaging profile generated by T cells from people with obesity is metformin resistant
A unique inflammaging profile generated by T cells from people with obesity is metformin resistant
The alarmingly high prevalence of obesity in older adults coupled with the negative health effects of chronic inflammation...
Plasma extracellular vesicles carry immune system-related peptides that predict human longevity
Plasma extracellular vesicles carry immune system-related peptides that predict human longevity
Extracellular vesicles (EVs) play crucial roles in aging. In this National Institutes on Aging-funded study, we sought to ...
Biomarkers of cellular senescence and major health outcomes in older adults
Biomarkers of cellular senescence and major health outcomes in older adults
The geroscience hypothesis proposes that underlying biological processes, such as the accumulation of senescent cells, hav...
Dietary phytochemicals alleviate the premature skin aging: A comprehensive review
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Spermidine alleviates thymopoiesis defects and aging of the peripheral T-cell population in mice after radiation exposure
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Association of handgrip strength asymmetry and weakness with intrinsic capacity impairment among older adults in China
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A complex systems approach to mosaic loss of the Y chromosome
A complex systems approach to mosaic loss of the Y chromosome
Mosaic loss of Y chromosome (mLOY) is an acquired condition wherein a sizeable proportion of an organ’s cells have l...
Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice
Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice
Ovarian aging is characterized by declines in follicular reserve and the emergence of mitochondrial dysfunction, reactive ...
Functional Ability and Survival of the Care Homes Residents Aged 85+: Ten-year Follow-up Study
Functional Ability and Survival of the Care Homes Residents Aged 85+: Ten-year Follow-up Study
Maintaining functional ability is an essential prerequisite for healthy ageing and might be of critical importance for rea...
Modeling functional loss in Alzheimer’s Disease through cognitive reserve and cognitive state: a panel data longitudinal study
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A novel 14mer peptide, T14, is associated with age-dependent behaviour in female mice
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A descriptive analysis of sarcopenia markers in young adults with down syndrome
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Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions
Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions
Many aspects of inflammation increase with aging in mice and humans. Transcriptomic analysis revealed that many murine ant...
Instruments and Measurement Scales for Cognitive Frailty in Midlife: A Systematic Literature Review from 2013 to 2023
Instruments and Measurement Scales for Cognitive Frailty in Midlife: A Systematic Literature Review from 2013 to 2023
This study is a systematic review addressing cognitive frailty, measurement instruments, and their impact on comprehensive...