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Long-term glucocorticoid infusion impairs epididymal adipocyte metabolism and maturation and affects miR-150-5p actions.
Long-term glucocorticoid infusion impairs epididymal adipocyte metabolism and maturation and affects miR-150-5p actions.
Available online 23 April 2024, 112250Author links open overlay panel, , , , , , , , , ABSTRACTThe most common form of hyp...
CENPK Orchestrates Ovarian Cancer Progression via GOLPH3-Mediated Activation of mTOR Signaling
CENPK Orchestrates Ovarian Cancer Progression via GOLPH3-Mediated Activation of mTOR Signaling
Ovarian cancer, characterized by its often-insidious nature and the paucity of specific symptoms or effective screening me...
FGF2 promotes the proliferation of injured granulosa cells in premature ovarian failure via Hippo-YAP signaling pathway
FGF2 promotes the proliferation of injured granulosa cells in premature ovarian failure via Hippo-YAP signaling pathway
Premature ovarian failure (POF) is characterized by diminished ovarian function, resulting in amenorrhea, low estrogen lev...
Inhibition of miR-146b-5p alleviates isoprenaline-induced cardiac hypertrophy via regulating DFCP1
Inhibition of miR-146b-5p alleviates isoprenaline-induced cardiac hypertrophy via regulating DFCP1
Pathological cardiac hypertrophy, which is characterized by cardiomyocyte enlargement and ventricular wall thickening, ini...
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis
Luteinizing hormone (LH) is essential for reproduction, controlling ovulation and steroidogenesis. Its receptor (LHR) recr...
Nuclear localization signal in nuclear receptor VDR facilitates the mitotic genome bookmarking by involving distinct amino acid residues
Nuclear localization signal in nuclear receptor VDR facilitates the mitotic genome bookmarking by involving distinct amino acid residues
Nuclear receptors (NRs) are defined as ligand-inducible transcriptional regulators for thousands of their target genes tha...
The gonadotropin-releasing hormone (GnRH) superfamily across Pancrustacea/Tetraconata: A role in metabolism?
The gonadotropin-releasing hormone (GnRH) superfamily across Pancrustacea/Tetraconata: A role in metabolism?
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Sexual Dimorphism's Impact on Adipogenesis: A Three-dimensional In Vitro Model Treated with 17β-estradiol and Testosterone
Sexual Dimorphism's Impact on Adipogenesis: A Three-dimensional In Vitro Model Treated with 17β-estradiol and Testosterone
Obesity is characterized by abnormal or excessive fat accumulation and is a serious public health concern worldwide. In th...
Cardiac dysfunction in sucrose-fed rats is associated with alterations of phospholamban phosphorylation and TNF-α levels
Cardiac dysfunction in sucrose-fed rats is associated with alterations of phospholamban phosphorylation and TNF-α levels
Changes in food consumption patterns towards diets rich in fat and sugar have contributed to a rapid increase in overweigh...
Multiple metabolic signals in the CeA regulate feeding: The role of AMPK
Multiple metabolic signals in the CeA regulate feeding: The role of AMPK
Obesity has increased significantly in the last five decades, reaching regular numbers of a pandemic (Blüher, 2019). Toget...
Prevalence of pathogenic variants and digenic disease in patients diagnosed with normosmic hypogonadotropic hypogonadism/Kallmann Syndrome
Prevalence of pathogenic variants and digenic disease in patients diagnosed with normosmic hypogonadotropic hypogonadism/Kallmann Syndrome
A normal functioning reproductive axis is dependent upon the pulsatile release of gonadotropin releasing hormone (GnRH) fr...
Heterozygous ZNHIT3 variants within the 17q12 recurrent deletion region are associated with Mayer-Rokitansky-Kuster Hauser (MRKH) syndrome
Heterozygous ZNHIT3 variants within the 17q12 recurrent deletion region are associated with Mayer-Rokitansky-Kuster Hauser (MRKH) syndrome
Development of the Mullerian system, which forms the fallopian tubes, uterus and upper vagina, occurs intertwined with dev...
Developmental programming: Testosterone excess masculinizes female pancreatic transcriptome and function in sheep
Developmental programming: Testosterone excess masculinizes female pancreatic transcriptome and function in sheep
Hyperandrogenic disorders such as polycystic ovary syndrome (PCOS) are often accompanied by metabolic dysfunction (Manzano...
Liraglutide promotes UCP1 expression and lipolysis of adipocytes by promoting the secretion of irisin from skeletal muscle cells
Liraglutide promotes UCP1 expression and lipolysis of adipocytes by promoting the secretion of irisin from skeletal muscle cells
Type 2 diabetes mellitus (T2DM) has become a new global pandemic due to the prevalence of Westernized diets and unhealthy ...
Exosomes from adipose-derived mesenchymal stem cell improve diabetic wound healing and inhibit fibrosis via miR-128-1-5p/TGF-β1/Smad axis
Exosomes from adipose-derived mesenchymal stem cell improve diabetic wound healing and inhibit fibrosis via miR-128-1-5p/TGF-β1/Smad axis
Diabetes is an increasingly prevalent chronic metabolic disorder that affects approximately 537 million adults worldwide b...
Maternal malnutrition associated with postnatal sugar consumption increases inflammatory response and prostate disorders in rat offspring
Maternal malnutrition associated with postnatal sugar consumption increases inflammatory response and prostate disorders in rat offspring
Over the past several decades, the Developmental Origins of the Health and Disease (DOHaD) concept (Schulz, 2010) has emer...
Photoperiod, but not progesterone, has a strong impact upon the transcriptome of the medio-basal hypothalamus in female goats and ewes
Photoperiod, but not progesterone, has a strong impact upon the transcriptome of the medio-basal hypothalamus in female goats and ewes
Photoperiod is the main environmental driver of seasonal responses in organisms living at temperate and polar latitudes. O...
Developmental programming: An exploratory analysis of pancreatic islet compromise in female sheep resulting from gestational BPA exposure
Developmental programming: An exploratory analysis of pancreatic islet compromise in female sheep resulting from gestational BPA exposure
Exposure to adverse environmental factors early in development can lead to poor birth outcomes and higher risk for the dev...
Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes
Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes
Diabetes is a chronic disease characterized by a partial or absolute lack of insulin synthesis, secretion, and insulin res...
Elevated chorionic gonadotropic hormone in transgenic mice induces parthenogenetic activation and ovarian teratomas
Elevated chorionic gonadotropic hormone in transgenic mice induces parthenogenetic activation and ovarian teratomas
Along with luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH), human chor...
Neuroendocrine functions of monoamines in invertebrates: Focus on bivalve molluscs
Neuroendocrine functions of monoamines in invertebrates: Focus on bivalve molluscs
Monoamines (MA) are neurotransmitters or endocrine modulators that contain an amino group connected to an aromatic ring by...
Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis
Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis
Available online 22 March 2024, 112212Author links open overlay panel, , , , , , , , , , , , , , , , Highlights•Discovery ...
16α-OHE1 alleviates hypoxia-induced inflammation and myocardial damage via the activation of β2-Adrenergic receptor
16α-OHE1 alleviates hypoxia-induced inflammation and myocardial damage via the activation of β2-Adrenergic receptor
Hypoxia is a form of physiological stress characterized by insufficient oxygen supply to bodily tissues, which has emerged...
Endocrine factors modulating vitellogenesis and oogenesis in insects: An update
Endocrine factors modulating vitellogenesis and oogenesis in insects: An update
The large populations and great variety of insects, with over a million species known, are related to their high rates of ...
Intestinal alterations and mild glucose homeostasis impairments in the offspring born to overweight rats
Intestinal alterations and mild glucose homeostasis impairments in the offspring born to overweight rats
Obesity has become a threat to global metabolic health. Obesity rates have risen to 511 million people with a body mass in...
Single microcystin exposure impairs the hypothalamic-pituitary-gonadal axis at different levels in female rats
Single microcystin exposure impairs the hypothalamic-pituitary-gonadal axis at different levels in female rats
Industrial progress has resulted in the improper disposal of wastewater containing pollutants into rivers and lakes ( S. L...
Uterine histopathology and steroid metabolism in a polycystic ovary syndrome rat model
Uterine histopathology and steroid metabolism in a polycystic ovary syndrome rat model
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders, affecting 7–12 % of women of reproductive ...
Association between nitric oxide synthase (NOS3) gene polymorphisms and diabetic nephropathy: An updated meta-analysis
Association between nitric oxide synthase (NOS3) gene polymorphisms and diabetic nephropathy: An updated meta-analysis
Alarming statistics shows a constant increase in the number of people with type 2 diabetes mellitus (T2DM) – by 49% over a...
Autophagy inhibition suppresses hormone production and cell growth in pituitary tumor cells: A potential approach to pituitary tumors
Autophagy inhibition suppresses hormone production and cell growth in pituitary tumor cells: A potential approach to pituitary tumors
Pituitary tumors (PTs): PTs are common, occurring in almost 17% of the population over the lifetime (Daly et al., 2006; Fe...
Excess homocysteine inhibits pancreatic β-cell secretory function by repressing Zbtb20 expression
Excess homocysteine inhibits pancreatic β-cell secretory function by repressing Zbtb20 expression
Homocysteine (Hcy) is a sulfur-containing nonprotein amino acid derived from the metabolism of methionine. Elevated levels...
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