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Congenital diaphragmatic hernia: phosphodiesterase-5 and Arginase inhibitors prevent pulmonary vascular hypoplasia in rat lungs
Congenital diaphragmatic hernia: phosphodiesterase-5 and Arginase inhibitors prevent pulmonary vascular hypoplasia in rat lungs
Severe pulmonary hypoplasia related to congenital diaphragmatic hernia (CDH) continues to be a potentially fatal condition...
The association between BMI trajectories and bronchopulmonary dysplasia among very preterm infants
The association between BMI trajectories and bronchopulmonary dysplasia among very preterm infants
To investigate the association between change in body mass index (BMI) from birth to 36 weeks gestation (ΔBMI) and br...
Parental concern for clinically vulnerable child during first 18 months of the COVID pandemic
Parental concern for clinically vulnerable child during first 18 months of the COVID pandemic
The uncertainties surrounding the COVID-19 pandemic have been associated with increased parental concern. The aim of this ...
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets
Postnatal lean mass accretion is commonly reduced in preterm infants. This study investigated mechanisms involved in the b...
Artificial intelligence in bronchopulmonary dysplasia- current research and unexplored frontiers
Geetha, O. et al. New Bpd-prevalence and risk factors for bronchopulmonary dysplasia/mortality in extremely low gestationa...
Autonomic markers of extubation readiness in premature infants
Autonomic markers of extubation readiness in premature infants
In premature infants, extubation failure is common and difficult to predict. Heart rate variability (HRV) is a marker of a...
Changes in depressive and anxiety symptoms during COVID-19 in children from the PROGRESS cohort
We assessed associations between maternal stress, social support, and child resiliency during the COVID-19 pandemic in rel...
Humoral and cellular response to the COVID-19 vaccine in immunocompromised children
Humoral and cellular response to the COVID-19 vaccine in immunocompromised children
A suboptimal response to the 2-dose COVID-19 vaccine series in the immunocompromised population prompted recommendations f...
The use of machine learning and artificial intelligence within pediatric critical care
The use of machine learning and artificial intelligence within pediatric critical care
The field of pediatric critical care has been hampered in the era of precision medicine by our inability to accurately def...
Bedside tracking of functional autonomic age in preterm infants
Bedside tracking of functional autonomic age in preterm infants
Preterm birth predisposes infants to adverse outcomes that, without early intervention, impacts their long-term health. To...
Early skin-to-skin contact and risk of late-onset-sepsis in very and extremely preterm infants
Early skin-to-skin contact and risk of late-onset-sepsis in very and extremely preterm infants
To evaluate the association between exposure to early skin-to-skin contact (SSC) and incidence of late-onset sepsis (LOS) ...
Multisystemic Inflammatory Syndrome in Children: a step towards a better understanding of this entity
As pediatricians, we all have to deal with new childhood inflammatory disorder due to COVID 19: the Multisystem Inflammato...
Left ventricular function before and after percutaneous patent ductus arteriosus closure in preterm infants
Left ventricular function before and after percutaneous patent ductus arteriosus closure in preterm infants
Definitive closure of the patent ductus arteriosus (PDA) is associated with significant changes in the loading conditions ...
Cardiovascular outcomes in children with Kawasaki disease: a population-based cohort study
Cardiovascular outcomes in children with Kawasaki disease: a population-based cohort study
The risk of cardiovascular events after Kawasaki disease (KD) remains uncertain. Our objective was to determine the risk o...
Placental microRNAs relate to early childhood growth trajectories
Placental microRNAs relate to early childhood growth trajectories
Poor placental function is a common cause of intrauterine growth restriction, which in turn is associated with increased r...
Evolving antibiotic resistance in Group B Streptococci causing invasive infant disease: 1970–2021
Evolving antibiotic resistance in Group B Streptococci causing invasive infant disease: 1970–2021
We sought to define the frequency of antibiotic resistance over time in a collection of invasive GBS isolates derived from...
Effects of human milk on body composition and growth in very low birthweight infants
Effects of human milk on body composition and growth in very low birthweight infants
To compare body composition and growth in very low birthweight infants according to their source of human milk: maternal e...
Association between PTPN1 polymorphisms and obesity-related phenotypes in European adolescents: influence of physical activity
To study the associations of Protein Tyrosine Phosphatase-N1 (PTPN1) polymorphisms with obesity-related phenotypes in Euro...
Incidence of anxiety and depression in children and young people with life-limiting conditions
Incidence of anxiety and depression in children and young people with life-limiting conditions
The aim of this study was to investigate the incidence of anxiety and depression in children and young people with life-li...
Global pediatric research investigator: Professor Khaled Saad
Biography: Dr. Khaled Saad is a Professor of Pediatrics at Assiut University in Asyut, Egypt. He obtained his undergraduat...
Oxygenation in the NICU: there is more to it than meets the eye
Saito, Y. et al. The progression of retinopathy of prematurity and fluctuation in blood gas tension. Graefes Arch. Clin. E...
Higher blood pressure in adolescent boys after very preterm birth and fetal growth restriction
Higher blood pressure in adolescent boys after very preterm birth and fetal growth restriction
Although preterm birth predisposes for cardiovascular disease, recent studies in children indicate normal blood pressure a...
Indigenous participation in pediatric Indigenous health research in Canada: a systematic review
Indigenous participation in pediatric Indigenous health research in Canada: a systematic review
For health inequities to be successfully addressed through health research, it is necessary for researchers to strive for ...
Dr Audrey E. Evans (1925–2022): academic trailblazer par excellence
Dr Audrey E. Evans (1925–2022): academic trailblazer par excellence
Dr Audrey Elizabeth Evans, emeritus Professor of Pediatrics at the University of Pennsylvania, died peacefully at home on ...
Impaired in vivo feto-placental development is associated with neonatal neurobehavioral outcomes
Impaired in vivo feto-placental development is associated with neonatal neurobehavioral outcomes
Fetal growth restriction (FGR) is a risk factor for neurodevelopmental problems, yet remains poorly understood. We sought ...
Bronchopulmonary dysplasia is not related to neurofilament light for neuroaxonal damage in preterm infants
Bronchopulmonary dysplasia is not related to neurofilament light for neuroaxonal damage in preterm infants
Neurofilament light (NfL) has been identified as a biomarker for neuroaxonal damage in preterm infants, but its relation w...
Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling
Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling
This study aimed to explore the functions of ubiquitin-specific protease 5 (USP5) in the endothelial inflammation of Kawas...
Novel approaches to capturing and using continuous cardiorespiratory physiological data in hospitalized children
Novel approaches to capturing and using continuous cardiorespiratory physiological data in hospitalized children
Continuous cardiorespiratory physiological monitoring is a cornerstone of care in hospitalized children. The data generate...
Large-scale brain network dynamics in very preterm children and relationship with socio-emotional outcomes: an exploratory study
Large-scale brain network dynamics in very preterm children and relationship with socio-emotional outcomes: an exploratory study
Children born very preterm (VPT; <32 weeks’ gestation) are at high risk of neurodevelopmental and behavioural...
PDA, a ringside view
The harsh light shines on the luminaries in the ring Fighting, arguing about you ...