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Exosomes and solid cancer therapy: where are we now?
Exosomes and solid cancer therapy: where are we now?
Cancer immunotherapy has revolutionized oncology, offering new hope for patients with previously incurable cancers. Howeve...
Ovarian cancer and its management through advanced drug delivery system
Ovarian cancer and its management through advanced drug delivery system
Ovarian cancer is the deadliest gynecological cancer, often being diagnosed at a late-stage when the disease is already ad...
Recent advancements in nanoparticles for cancer treatment
Recent advancements in nanoparticles for cancer treatment
Nanotechnology is a significant factor that has assisted researchers in overcoming medications’ permeability and ret...
Evaluation of the anticancer effects of hydroxycinnamic acid isomers on breast cancer stem cells
Evaluation of the anticancer effects of hydroxycinnamic acid isomers on breast cancer stem cells
Research on breast cancer stem cells (BCSCs) is crucial for improving our understanding of their roles in tumor resistance...
Ingenol mebutate in cancer therapy: mechanisms, clinical applications and future directions
Ingenol mebutate in cancer therapy: mechanisms, clinical applications and future directions
Ingenol mebutate (IM), a diterpene ester derived from Euphorbia species, has demonstrated promising anticancer properties ...
Chylothorax in thoracic oncology: diagnostic challenges and management strategies
Chylothorax in thoracic oncology: diagnostic challenges and management strategies
Chylothorax is a distinctive form of pleural effusion characterized by the accumulation of chyle within the pleural space....
Pharmacogenomics influence on MDR1-associated cancer resistance and innovative drug delivery approaches: advancing precision oncology
Pharmacogenomics influence on MDR1-associated cancer resistance and innovative drug delivery approaches: advancing precision oncology
Currently, there is a growing concern surrounding the treatment of cancer, a formidable disease. Pharmacogenomics and pers...
Autophagy induced by metabolic processes leads to solid tumor cell metastatic dormancy and recurrence
Autophagy induced by metabolic processes leads to solid tumor cell metastatic dormancy and recurrence
A crucial cellular mechanism that has a complex impact on the biology of cancer, particularly in solid tumors, is autophag...
Natural compounds as modulators of miRNAs: a new frontier in bladder cancer treatment
Natural compounds as modulators of miRNAs: a new frontier in bladder cancer treatment
Bladder cancer (BC) is a major global health issue with a high recurrence rate and limited effective treatments. Over the ...
Research progress on N6-methyladenosine RNA modification in osteosarcoma: functions, mechanisms, and potential clinical applications
Research progress on N6-methyladenosine RNA modification in osteosarcoma: functions, mechanisms, and potential clinical applications
Osteosarcoma (OS) is the most commonly diagnosed primary malignant bone tumor in children and adolescents. Despite signifi...
Ameliorative effect of aqueous leaf extract of Pistacia lentiscus L. against oxaliplatin-induced hepatic injury, oxidative stress, and DNA damage in vitro and in vivo
Ameliorative effect of aqueous leaf extract of Pistacia lentiscus L. against oxaliplatin-induced hepatic injury, oxidative stress, and DNA damage in vitro and in vivo
The current study aimed to assess the preventive effects of aqueous leaf extract of Pistacia lentiscus (ALEPL) against Oxa...
Nanotechnology-based biomedical devices in the cancer diagnostics and therapy
Nanotechnology-based biomedical devices in the cancer diagnostics and therapy
Nanotechnology has significantly transformed the field of cancer diagnostics and therapeutics by introducing advanced biom...
The impact of apoptosis-inducing MAPK and glycolytic pathways modulated by Aloe vera and royal jelly in lung and colorectal cancer
The impact of apoptosis-inducing MAPK and glycolytic pathways modulated by Aloe vera and royal jelly in lung and colorectal cancer
Lung and colon cancer are among the most commonly diagnosed and fatal cancer types in the world. Due to their metastatic p...
Fusion of tumor cells and mesenchymal stem/stroma cells: a source of tumor heterogeneity, evolution and recurrence
Fusion of tumor cells and mesenchymal stem/stroma cells: a source of tumor heterogeneity, evolution and recurrence
The heterogeneity and evolution of tumors remain significant obstacles in cancer treatment, contributing to both therapy r...
Enhanced antitumor efficacy of nanostructured lipid carrier co-loaded with docetaxel and 5-fluorouracil for targeted gastric cancer therapy
Enhanced antitumor efficacy of nanostructured lipid carrier co-loaded with docetaxel and 5-fluorouracil for targeted gastric cancer therapy
This study presents nanostructured lipid carrier (NLC) co-loaded with Docetaxel (DCT) and 5-Fluorouracil (5-FU) as a targe...
Emerging nanoplatforms towards microenvironment-responsive glioma therapy
Emerging nanoplatforms towards microenvironment-responsive glioma therapy
Gliomas are aggressive intracranial tumors of the central nervous system with a poor prognosis, high risk of recurrence, a...
Targeting the Hippo and Rap1 signaling pathways: the anti-proliferative effects of curcumin in colorectal cancer cell lines
Targeting the Hippo and Rap1 signaling pathways: the anti-proliferative effects of curcumin in colorectal cancer cell lines
CRC has the third-highest cancer incidence and death. Many human cancers, including colorectal cancer, are connected to ab...
Study of the effect of zinc oxide, selenium, and silver nanoparticles on the expression level of oxidative stress-associated genes in ovarian cancer
Study of the effect of zinc oxide, selenium, and silver nanoparticles on the expression level of oxidative stress-associated genes in ovarian cancer
Reactive oxygen species (ROS) generated by oxidative stress have emerged as critical factors in the pathophysiology of mal...
Investigation of potential anti-metastatic effect of metformin and caffeic acid combination therapy in breast cancer cell line in in-vitro culture model
Investigation of potential anti-metastatic effect of metformin and caffeic acid combination therapy in breast cancer cell line in in-vitro culture model
The invasion and metastasis of cancer cells transform localized cancers into systemic and life-threatening diseases, posin...
Unraveling non-coding RNAs in breast cancer: mechanistic insights and therapeutic potential
Unraveling non-coding RNAs in breast cancer: mechanistic insights and therapeutic potential
Breast cancer remains a leading global health challenge requiring innovative, therapeutic strategies to improve patient ou...
Baicalein, a natural flavonoid in gastrointestinal cancers treatment: recent trends and future perspectives
Baicalein, a natural flavonoid in gastrointestinal cancers treatment: recent trends and future perspectives
Gastrointestinal cancer is a malignant condition of the gastrointestinal tract (GI) which affect multi-organs of digestive...
Nanobodies as innovative immune checkpoint modulators: advancing cancer immunotherapy
Nanobodies as innovative immune checkpoint modulators: advancing cancer immunotherapy
The immune system relies on a delicate balance between attacking harmful pathogens and preserving the body’s own tis...
Advancing miRNA cancer research through artificial intelligence: from biomarker discovery to therapeutic targeting
Advancing miRNA cancer research through artificial intelligence: from biomarker discovery to therapeutic targeting
MicroRNAs (miRNAs), a class of small non-coding RNAs, play a vital role in regulating gene expression at the post-transcri...
Sorcin: mechanisms of action in cancer hallmarks, drug resistance and opportunities in therapeutics
Sorcin: mechanisms of action in cancer hallmarks, drug resistance and opportunities in therapeutics
Soluble resistant related calcium binding protein (Sorcin) plays an important role in tumor progression, angiogenesis, met...
Salmonella-based therapeutic strategies: improving tumor microenvironment and bringing new hope for cancer immunotherapy
Salmonella-based therapeutic strategies: improving tumor microenvironment and bringing new hope for cancer immunotherapy
Immunotherapy has revolutionized cancer treatment, yet its effectiveness is limited by immunosuppressive tumor microenviro...
LncRNAs in modulating cancer cell resistance to paclitaxel (PTX) therapy
LncRNAs in modulating cancer cell resistance to paclitaxel (PTX) therapy
Paclitaxel (PTX) is widely used for treating several cancers, including breast, ovarian, lung, esophageal, gastric, pancre...
Cedrus atlantica extract inhibits melanoma progression by suppressing epithelial-mesenchymal transition and inducing mitochondria-mediated apoptosis
Cedrus atlantica extract inhibits melanoma progression by suppressing epithelial-mesenchymal transition and inducing mitochondria-mediated apoptosis
Melanoma has a low incidence, accounting for less than 5% of skin cancers; however, it is the most lethal cancer, primaril...
The physician payments Sunshine Act and medical oncology: a seven-year financial analysis
The physician payments Sunshine Act and medical oncology: a seven-year financial analysis
The integration of pharmaceutical and medical device companies with clinical practice is under scrutiny due to financial i...
Associations between the life’s essential 8, genetic risk and breast cancer incidence in premenopausal and postmenopausal women: a prospective study in UK Biobank
Associations between the life’s essential 8, genetic risk and breast cancer incidence in premenopausal and postmenopausal women: a prospective study in UK Biobank
The combined effect of cardiovascular risk factors on breast cancer in women is unknown. The relationship between genetic ...
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma
AXL has ubiquitous expression in multiple cancers, and is strongly linked to both tumor progression, metastasis, and poor ...
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