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Incidence of lymphedema related to various cancers
Incidence of lymphedema related to various cancers
Cancer-related lymphedema (CRL) lacks internationally accepted definition and diagnostic criteria. The accurate incidence ...
Turning the tide: pembrolizumab’s triumph in adjuvant RCC therapy
Turning the tide: pembrolizumab’s triumph in adjuvant RCC therapy
In recent years, kidney cancer has shown an increased worldwide incidence of more than 400 000 novel cases annually. Altho...
Current diagnostic and quantitative techniques in the field of lymphedema management: a critical review
Current diagnostic and quantitative techniques in the field of lymphedema management: a critical review
Lymphedema evaluation entails multifaceted considerations for which options continue to evolve and emerge. This paper prov...
Lipid metabolism reprogramming in renal cell carcinomas
Lipid metabolism reprogramming in renal cell carcinomas
This study investigates the intricate mechanisms underlying the correlation between elevated consumption of harmful fats a...
Advances in immunotoxin engineering: precision therapeutic strategies in modern oncology
Advances in immunotoxin engineering: precision therapeutic strategies in modern oncology
Immunotoxins (ITs) are specialized therapeutic agents designed for targeted treatment, particularly in cancer therapy. The...
The role of IL-22 in cancer
The role of IL-22 in cancer
Interleukin-22, discovered in the year of 2000, is a pleiotropic Th17 cytokine from the IL-10 family of cytokines. IL-22 s...
How mitochondrial dynamics imbalance affects the progression of breast cancer:a mini review
How mitochondrial dynamics imbalance affects the progression of breast cancer:a mini review
Despite the high incidence of breast cancer in women worldwide, there are still great challenges in the treatment process....
The treatment landscape of triple-negative breast cancer
The treatment landscape of triple-negative breast cancer
Triple-negative breast cancer (TNBC) tumors are biologically aggressive breast cancer. On the molecular level, TNBC is a h...
2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α
2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α
The clinical studies for breast cancer (BC) are now assessing the efficacy of 2-Methoxyestradiol (2-ME), a naturally occur...
The potential of lenvatinib in breast cancer therapy
The potential of lenvatinib in breast cancer therapy
Breast cancer, as a highly prevalent cancer among women, is one of the main causes of female mortality due to cancer. Ther...
A new therapeutic strategy for luminal A-breast cancer treatment: vulpinic acid as an anti-neoplastic agent induces ferroptosis and apoptosis mechanisms
A new therapeutic strategy for luminal A-breast cancer treatment: vulpinic acid as an anti-neoplastic agent induces ferroptosis and apoptosis mechanisms
Breast cancer is a common invasive tumor in women, and the most common subtype of breast cancer is luminal A. Hormonal the...
Immunomodulation aspects of gut microbiome-related interventional strategies in colorectal cancer
Immunomodulation aspects of gut microbiome-related interventional strategies in colorectal cancer
Colorectal cancer (CRC), the third most common cancer worldwide, develops mainly due to the accumulation of genetic and ep...
Cancer/testis antigen expression and co-expression patterns in gastroesophageal adenocarcinoma
Cancer/testis antigen expression and co-expression patterns in gastroesophageal adenocarcinoma
Gastroesophageal adenocarcinoma (GEAC) poses a significant challenge due to its poor prognosis and limited treatment optio...
Therapeutic response and safety of radioligand therapy with 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer patients
Therapeutic response and safety of radioligand therapy with 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer patients
Prostate cancer is one of the most common cancers and leading cause of death due to cancer across the globe. This persuade...
Unveiling the potency of FDA-approved oxidopamine HBr for cervical cancer regulation and replication proteins
Unveiling the potency of FDA-approved oxidopamine HBr for cervical cancer regulation and replication proteins
Cervical Cancer remains a women’s health concern worldwide and ranks among the most prevalent cancers, particularly ...
Impact of microRNA variants on PI3K/AKT signaling in triple-negative breast cancer: comprehensive review
Impact of microRNA variants on PI3K/AKT signaling in triple-negative breast cancer: comprehensive review
Breast cancer (BC) is a significant cause of cancer-related mortality, and triple-negative breast cancer (TNBC) is a parti...
Diverse roles of aldolase enzymes in cancer development, drug resistance and therapeutic approaches as moonlighting enzymes
Diverse roles of aldolase enzymes in cancer development, drug resistance and therapeutic approaches as moonlighting enzymes
Aldolase enzymes, particularly ALDOA, ALDOB, and ALDOC, play a crucial role in the development and progression of cancer. ...
Tetrahydroisoquinoline reduces angiogenesis by interacting myeloma cells with HUVECs mediated by extracellular vesicles
Tetrahydroisoquinoline reduces angiogenesis by interacting myeloma cells with HUVECs mediated by extracellular vesicles
Multiple myeloma (MM) is a neoplastic condition resulting from the uncontrolled expansion of B-cell-derived plasma cells. ...
Emerging roles of the chromatin remodeler MORC2 in cancer metabolism
Emerging roles of the chromatin remodeler MORC2 in cancer metabolism
Cancer is characterized by metabolic reprogramming in cancer cells, which is crucial for tumorigenesis. The highly deregul...
Doxorubicin downregulates cell cycle regulatory hub genes in breast cancer cells
Doxorubicin downregulates cell cycle regulatory hub genes in breast cancer cells
Breast cancer (BC) is the leading commonly diagnosed cancer in the world, with complex mechanisms underlying its developme...
Marine sponge-derived alkaloid inhibits the PI3K/AKT/mTOR signaling pathway against diffuse large B-cell lymphoma
Marine sponge-derived alkaloid inhibits the PI3K/AKT/mTOR signaling pathway against diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous non-Hodgkin lymphoma that is extremely aggressive and...
Unraveling the influence of LncRNA in gastric cancer pathogenesis: a comprehensive review focus on signaling pathways interplay
Unraveling the influence of LncRNA in gastric cancer pathogenesis: a comprehensive review focus on signaling pathways interplay
Gastric cancers (GCs) are among the most common and fatal malignancies in the world. Despite our increasing understanding ...
Cabazitaxel as a promising therapy for cisplatin-resistant bladder cancer: a preliminary study
Cabazitaxel as a promising therapy for cisplatin-resistant bladder cancer: a preliminary study
Bladder cancer is a common malignancy worldwide, posing a substantial healthcare challenge. Current standard treatment reg...
Gd-GQDs as nanotheranostic platform for the treatment of HPV-positive oropharyngeal cancer
Gd-GQDs as nanotheranostic platform for the treatment of HPV-positive oropharyngeal cancer
In this study, we developed new gadolinium-graphene quantum dot nanoparticles (Gd-GQDs) as a theranostic platform for magn...
Anticancer effects of Artemisia campestris extract on acute myeloid leukemia cells: an ex vivo study
Anticancer effects of Artemisia campestris extract on acute myeloid leukemia cells: an ex vivo study
Cure rates for acute myeloid leukemia (AML) remain suboptimal; thus, new treatment strategies are needed for this deadly d...
PARK2 suppresses the proliferation of high-grade serous ovarian carcinoma via inducing the proteasomal degradation of ZNF703
PARK2 suppresses the proliferation of high-grade serous ovarian carcinoma via inducing the proteasomal degradation of ZNF703
High-grade serous ovarian cancer (HGSC) is an aggressive disease with poor prognosis. The oncoprotein ZNF703 is implicated...
Exploring the potential of tocopherols: mechanisms of action and perspectives in the prevention and treatment of breast cancer
Exploring the potential of tocopherols: mechanisms of action and perspectives in the prevention and treatment of breast cancer
Currently, breast cancer is the most common cause of mortality caused by neoplasia in women worldwide. The unmet ...
Current advances in cancer energy metabolism under dietary restriction: a mini review
Current advances in cancer energy metabolism under dietary restriction: a mini review
The manipulation of the energy or source of food for cancer cells has attracted significant attention in oncology research...
Targeted gene therapy for cancer: the impact of microRNA multipotentiality
Targeted gene therapy for cancer: the impact of microRNA multipotentiality
Cancer is a life-threatening disease and its management is difficult due to its complex nature. Cancer is characterized by...
Allicin: a promising modulator of apoptosis and survival signaling in cancer
Allicin: a promising modulator of apoptosis and survival signaling in cancer
According to the World Health Organization, cancer is the foremost cause of mortality globally. Various phytochemicals fro...
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