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Emerging nanoplatforms towards microenvironment-responsive glioma therapy
Emerging nanoplatforms towards microenvironment-responsive glioma therapy
Gliomas are aggressive intracranial tumors of the central nervous system with a poor prognosis, high risk of recurrence, a...
Targeting the Hippo and Rap1 signaling pathways: the anti-proliferative effects of curcumin in colorectal cancer cell lines
Targeting the Hippo and Rap1 signaling pathways: the anti-proliferative effects of curcumin in colorectal cancer cell lines
CRC has the third-highest cancer incidence and death. Many human cancers, including colorectal cancer, are connected to ab...
Study of the effect of zinc oxide, selenium, and silver nanoparticles on the expression level of oxidative stress-associated genes in ovarian cancer
Study of the effect of zinc oxide, selenium, and silver nanoparticles on the expression level of oxidative stress-associated genes in ovarian cancer
Reactive oxygen species (ROS) generated by oxidative stress have emerged as critical factors in the pathophysiology of mal...
Investigation of potential anti-metastatic effect of metformin and caffeic acid combination therapy in breast cancer cell line in in-vitro culture model
Investigation of potential anti-metastatic effect of metformin and caffeic acid combination therapy in breast cancer cell line in in-vitro culture model
The invasion and metastasis of cancer cells transform localized cancers into systemic and life-threatening diseases, posin...
Unraveling non-coding RNAs in breast cancer: mechanistic insights and therapeutic potential
Unraveling non-coding RNAs in breast cancer: mechanistic insights and therapeutic potential
Breast cancer remains a leading global health challenge requiring innovative, therapeutic strategies to improve patient ou...
Baicalein, a natural flavonoid in gastrointestinal cancers treatment: recent trends and future perspectives
Baicalein, a natural flavonoid in gastrointestinal cancers treatment: recent trends and future perspectives
Gastrointestinal cancer is a malignant condition of the gastrointestinal tract (GI) which affect multi-organs of digestive...
Nanobodies as innovative immune checkpoint modulators: advancing cancer immunotherapy
Nanobodies as innovative immune checkpoint modulators: advancing cancer immunotherapy
The immune system relies on a delicate balance between attacking harmful pathogens and preserving the body’s own tis...
Advancing miRNA cancer research through artificial intelligence: from biomarker discovery to therapeutic targeting
Advancing miRNA cancer research through artificial intelligence: from biomarker discovery to therapeutic targeting
MicroRNAs (miRNAs), a class of small non-coding RNAs, play a vital role in regulating gene expression at the post-transcri...
Sorcin: mechanisms of action in cancer hallmarks, drug resistance and opportunities in therapeutics
Sorcin: mechanisms of action in cancer hallmarks, drug resistance and opportunities in therapeutics
Soluble resistant related calcium binding protein (Sorcin) plays an important role in tumor progression, angiogenesis, met...
Salmonella-based therapeutic strategies: improving tumor microenvironment and bringing new hope for cancer immunotherapy
Salmonella-based therapeutic strategies: improving tumor microenvironment and bringing new hope for cancer immunotherapy
Immunotherapy has revolutionized cancer treatment, yet its effectiveness is limited by immunosuppressive tumor microenviro...
LncRNAs in modulating cancer cell resistance to paclitaxel (PTX) therapy
LncRNAs in modulating cancer cell resistance to paclitaxel (PTX) therapy
Paclitaxel (PTX) is widely used for treating several cancers, including breast, ovarian, lung, esophageal, gastric, pancre...
Cedrus atlantica extract inhibits melanoma progression by suppressing epithelial-mesenchymal transition and inducing mitochondria-mediated apoptosis
Cedrus atlantica extract inhibits melanoma progression by suppressing epithelial-mesenchymal transition and inducing mitochondria-mediated apoptosis
Melanoma has a low incidence, accounting for less than 5% of skin cancers; however, it is the most lethal cancer, primaril...
The physician payments Sunshine Act and medical oncology: a seven-year financial analysis
The physician payments Sunshine Act and medical oncology: a seven-year financial analysis
The integration of pharmaceutical and medical device companies with clinical practice is under scrutiny due to financial i...
Associations between the life’s essential 8, genetic risk and breast cancer incidence in premenopausal and postmenopausal women: a prospective study in UK Biobank
Associations between the life’s essential 8, genetic risk and breast cancer incidence in premenopausal and postmenopausal women: a prospective study in UK Biobank
The combined effect of cardiovascular risk factors on breast cancer in women is unknown. The relationship between genetic ...
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma
AXL has ubiquitous expression in multiple cancers, and is strongly linked to both tumor progression, metastasis, and poor ...
Exosomes in esophageal cancer: function and therapeutic prospects
Exosomes in esophageal cancer: function and therapeutic prospects
Esophageal cancer (EC) is one of the most common malignant tumors worldwide. Exosomes are a type of extracellular vesicles...
An overview on the interaction between non-coding RNAs and CTLA-4 gene in human diseases
An overview on the interaction between non-coding RNAs and CTLA-4 gene in human diseases
Cytotoxic T lymphocyte antigen 4 (CTLA-4), in conjunction with PD-1 and CD28, plays a pivotal role in the modulation of T-...
Exploring the role of antigen-presenting cancer-associated fibroblasts and CD74 on the pancreatic ductal adenocarcinoma tumor microenvironment
Exploring the role of antigen-presenting cancer-associated fibroblasts and CD74 on the pancreatic ductal adenocarcinoma tumor microenvironment
Pancreatic ductal adenocarcinoma (PDAC) has proven to be a formidable cancer primarily due to its tumor microenvironment (...
Telomerase inhibition in breast cancer and breast cancer stem cells: a brief review
Telomerase inhibition in breast cancer and breast cancer stem cells: a brief review
Breast cancer is a major health problem, accounting for one third of all cancers in women. There is no definitive treatmen...
N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights
N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights
N6-methyladenosine (m6A) plays a pivotal role in regulating epitranscriptomic mechanisms and is closely linked to the norm...
Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis
Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis
The 5-fluorouracil (5-FU)-based chemotherapy regimen is a primary strategy for treating pancreatic cancer (PC). However, c...
Dual roles of extracellular vesicles in acute lymphoblastic leukemia: implications for disease progression and theranostic strategies
Dual roles of extracellular vesicles in acute lymphoblastic leukemia: implications for disease progression and theranostic strategies
Acute Lymphoblastic Leukemia (ALL) is a heterogeneous blood cancer characterized by the uncontrolled growth of immature ly...
PRIM2 promotes proliferation and metastasis of pancreatic ductal adenocarcinoma through interactions with FAM111B
PRIM2 promotes proliferation and metastasis of pancreatic ductal adenocarcinoma through interactions with FAM111B
Pancreatic ductal adenocarcinomas (PDAC) are huge threat to human for the extreme malignancy. PRIM2 was reported as tumor ...
Red wavelength-induced photobiomodulation enhances indocyanine green-based anticancer photodynamic therapy
Red wavelength-induced photobiomodulation enhances indocyanine green-based anticancer photodynamic therapy
Cancer is a global concern worldwide. Prostate cancer has high prevalence and mortality rates among men. Photodynamic ther...
Thapsigargin and its prodrug derivatives: exploring novel approaches for targeted cancer therapy through calcium signaling disruption
Thapsigargin and its prodrug derivatives: exploring novel approaches for targeted cancer therapy through calcium signaling disruption
Thapsigargin, a sesquiterpene lactone derived from Thapsia garganica L., has demonstrated mixed potential as an anticancer...
Recent advancements at ASCO 2024 in PD-L1 and PD-1 bispecific antibodies
Recent advancements at ASCO 2024 in PD-L1 and PD-1 bispecific antibodies
Recent advancements in cancer immunotherapy have spotlighted the PD-1/PD-L1 pathway, crucial for its role in immune checkp...
Clinicopathologic feature and treatment progress of high-grade ovarian neuroendocrine tumors
Clinicopathologic feature and treatment progress of high-grade ovarian neuroendocrine tumors
High-grade Ovarian neuroendocrine tumors represent a rare subset of ovarian neoplasms characterized by aggressive behavior...
lncRNAs’p potential roles in the pathogenesis of cancer via interacting with signaling pathways; special focus on lncRNA-mediated signaling dysregulation in lung cancer
lncRNAs’p potential roles in the pathogenesis of cancer via interacting with signaling pathways; special focus on lncRNA-mediated signaling dysregulation in lung cancer
Lung cancer ranks among the most lethal types of cancer globally, with a high occurrence and fatality rate. The spread of ...
CAP superfamily proteins in human: a new target for cancer therapy
CAP superfamily proteins in human: a new target for cancer therapy
The CAP (Cysteine-rich secretory protein, Antigen 5, and Pathogenesis-related protein 1) superfamily proteins (CAP protein...
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma
Radiotherapy is important in treating esophageal squamous cell carcinoma (ESCC) comprehensively. Resistance to radiotherap...
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