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Recent advancements at ASCO 2024 in PD-L1 and PD-1 bispecific antibodies
Recent advancements at ASCO 2024 in PD-L1 and PD-1 bispecific antibodies
Recent advancements in cancer immunotherapy have spotlighted the PD-1/PD-L1 pathway, crucial for its role in immune checkp...
Clinicopathologic feature and treatment progress of high-grade ovarian neuroendocrine tumors
Clinicopathologic feature and treatment progress of high-grade ovarian neuroendocrine tumors
High-grade Ovarian neuroendocrine tumors represent a rare subset of ovarian neoplasms characterized by aggressive behavior...
lncRNAs’p potential roles in the pathogenesis of cancer via interacting with signaling pathways; special focus on lncRNA-mediated signaling dysregulation in lung cancer
lncRNAs’p potential roles in the pathogenesis of cancer via interacting with signaling pathways; special focus on lncRNA-mediated signaling dysregulation in lung cancer
Lung cancer ranks among the most lethal types of cancer globally, with a high occurrence and fatality rate. The spread of ...
CAP superfamily proteins in human: a new target for cancer therapy
CAP superfamily proteins in human: a new target for cancer therapy
The CAP (Cysteine-rich secretory protein, Antigen 5, and Pathogenesis-related protein 1) superfamily proteins (CAP protein...
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma
Radiotherapy is important in treating esophageal squamous cell carcinoma (ESCC) comprehensively. Resistance to radiotherap...
Letter to the editor on “Targeted gene therapy for cancer: the impact of microRNA multipotentiality”
Letter to the editor on “Targeted gene therapy for cancer: the impact of microRNA multipotentiality”
Cite this articleAmeya, K.P., Sekar, D. Letter to the editor on “Targeted gene therapy for cancer: the impact of microRNA ...
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer
As the first anti-HER2 targeted agent approved by FDA in 1998, Trastuzumab has significantly improved the outcome of patie...
Understanding the chemistry & pharmacology of antibody–drug conjugates in triple-negative breast cancer with special reference to exatecan derivatives
Understanding the chemistry & pharmacology of antibody–drug conjugates in triple-negative breast cancer with special reference to exatecan derivatives
In the spectrum of breast malignancies, triple-negative breast cancer is the most widely spreading subtype of breast cance...
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a leading liver cancer that significantly impacts global life expectancy and remains cha...
Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery
Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery
Glioblastoma (GBM) is a highly prevalent and aggressive brain tumor in adults with limited treatment response, leading to ...
Post-operative care for patients following surgical treatment of lymphedema
Post-operative care for patients following surgical treatment of lymphedema
Surgical treatments are promising for the treatment of lymphedema. It is important for patients, healthcare providers, and...
Effectiveness of complete decongestive therapy for upper extremity breast cancer-related lymphedema: a review of systematic reviews
Effectiveness of complete decongestive therapy for upper extremity breast cancer-related lymphedema: a review of systematic reviews
Breast cancer-related lymphedema (BCRL) remains a challenging condition impacting function and quality of life. Complete d...
Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel
Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel
Several recent studies have investigated the validity of precautionary practices for lymphedema risk reduction after breas...
Advancements in long non-coding RNA-based therapies for cancer: targeting, delivery, and clinical implications
Advancements in long non-coding RNA-based therapies for cancer: targeting, delivery, and clinical implications
Long non-coding RNAs (lncRNAs) have been in the spotlight for the past two decades due to their extensive role in regulati...
Introducing the ELPIS scale: a novel tool for measuring emotional empathy toward cancer patients
Introducing the ELPIS scale: a novel tool for measuring emotional empathy toward cancer patients
Empathy, defined as the ability to understand and share another person’s feelings, is crucial in the healthcare sett...
Incidence of lymphedema related to various cancers
Incidence of lymphedema related to various cancers
Cancer-related lymphedema (CRL) lacks internationally accepted definition and diagnostic criteria. The accurate incidence ...
Turning the tide: pembrolizumab’s triumph in adjuvant RCC therapy
Turning the tide: pembrolizumab’s triumph in adjuvant RCC therapy
In recent years, kidney cancer has shown an increased worldwide incidence of more than 400 000 novel cases annually. Altho...
Current diagnostic and quantitative techniques in the field of lymphedema management: a critical review
Current diagnostic and quantitative techniques in the field of lymphedema management: a critical review
Lymphedema evaluation entails multifaceted considerations for which options continue to evolve and emerge. This paper prov...
Lipid metabolism reprogramming in renal cell carcinomas
Lipid metabolism reprogramming in renal cell carcinomas
This study investigates the intricate mechanisms underlying the correlation between elevated consumption of harmful fats a...
Advances in immunotoxin engineering: precision therapeutic strategies in modern oncology
Advances in immunotoxin engineering: precision therapeutic strategies in modern oncology
Immunotoxins (ITs) are specialized therapeutic agents designed for targeted treatment, particularly in cancer therapy. The...
The role of IL-22 in cancer
The role of IL-22 in cancer
Interleukin-22, discovered in the year of 2000, is a pleiotropic Th17 cytokine from the IL-10 family of cytokines. IL-22 s...
How mitochondrial dynamics imbalance affects the progression of breast cancer:a mini review
How mitochondrial dynamics imbalance affects the progression of breast cancer:a mini review
Despite the high incidence of breast cancer in women worldwide, there are still great challenges in the treatment process....
The treatment landscape of triple-negative breast cancer
The treatment landscape of triple-negative breast cancer
Triple-negative breast cancer (TNBC) tumors are biologically aggressive breast cancer. On the molecular level, TNBC is a h...
2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α
2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α
The clinical studies for breast cancer (BC) are now assessing the efficacy of 2-Methoxyestradiol (2-ME), a naturally occur...
The potential of lenvatinib in breast cancer therapy
The potential of lenvatinib in breast cancer therapy
Breast cancer, as a highly prevalent cancer among women, is one of the main causes of female mortality due to cancer. Ther...
A new therapeutic strategy for luminal A-breast cancer treatment: vulpinic acid as an anti-neoplastic agent induces ferroptosis and apoptosis mechanisms
A new therapeutic strategy for luminal A-breast cancer treatment: vulpinic acid as an anti-neoplastic agent induces ferroptosis and apoptosis mechanisms
Breast cancer is a common invasive tumor in women, and the most common subtype of breast cancer is luminal A. Hormonal the...
Immunomodulation aspects of gut microbiome-related interventional strategies in colorectal cancer
Immunomodulation aspects of gut microbiome-related interventional strategies in colorectal cancer
Colorectal cancer (CRC), the third most common cancer worldwide, develops mainly due to the accumulation of genetic and ep...
Cancer/testis antigen expression and co-expression patterns in gastroesophageal adenocarcinoma
Cancer/testis antigen expression and co-expression patterns in gastroesophageal adenocarcinoma
Gastroesophageal adenocarcinoma (GEAC) poses a significant challenge due to its poor prognosis and limited treatment optio...
Therapeutic response and safety of radioligand therapy with 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer patients
Therapeutic response and safety of radioligand therapy with 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer patients
Prostate cancer is one of the most common cancers and leading cause of death due to cancer across the globe. This persuade...
Unveiling the potency of FDA-approved oxidopamine HBr for cervical cancer regulation and replication proteins
Unveiling the potency of FDA-approved oxidopamine HBr for cervical cancer regulation and replication proteins
Cervical Cancer remains a women’s health concern worldwide and ranks among the most prevalent cancers, particularly ...
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