SCI时时刷

search
+
Can beta-lactamase resistance genes in anaerobic Gram-negative gut bacteria transfer to gut aerobes?
Can beta-lactamase resistance genes in anaerobic Gram-negative gut bacteria transfer to gut aerobes?
The study was conceived with the hypothesis that human aerobic gut flora could act as a reservoir of ß-lactamases and...
Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells
Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells
Allantopyrone A is an α-pyrone metabolite that was originally isolated from the endophytic fungus Allantophomopsis ly...
Comprehensive analysis of biosynthetic gene clusters in bacteria and discovery of Tumebacillus as a potential producer of natural products
Comprehensive analysis of biosynthetic gene clusters in bacteria and discovery of Tumebacillus as a potential producer of natural products
Limited microbial genera such as Streptomyces have served as sources of natural products (NPs), whereas most others have b...
An efflux pump deletion mutant enabling the discovery of a macrolide as an overlooked anti-P. aeruginosa active compound
An efflux pump deletion mutant enabling the discovery of a macrolide as an overlooked anti-P. aeruginosa active compound
Antimicrobial resistance is a serious, worldwide problem. Pseudomonas aeruginosa (P. aeruginosa) is the pathogen that pose...
Design, synthesis and antibacterial activity of novel colistin derivatives with thioether bond-mediated cyclic scaffold
Design, synthesis and antibacterial activity of novel colistin derivatives with thioether bond-mediated cyclic scaffold
The escalating crisis of multidrug resistance is raising the fear of untreatable Gram-negative infections and killing a su...
Fluorothiazinon inhibits the virulence factors of uropathogenic Escherichia coli involved in the development of urinary tract infection
Fluorothiazinon inhibits the virulence factors of uropathogenic Escherichia coli involved in the development of urinary tract infection
Uropathogenic Escherichia coli (UPEC) is the most common pathogenic bacterium associated with urinary tract infection. Due...
Species-specific secondary metabolism by actinomycetes of the genus Phytohabitans and discovery of new pyranonaphthoquinones and isatin derivatives
Species-specific secondary metabolism by actinomycetes of the genus Phytohabitans and discovery of new pyranonaphthoquinones and isatin derivatives
To further exploit secondary metabolic potential of a minor actinomycete genus Phytohabitans within the family Micromonosp...
In vitro and in vivo synergistic wound healing and anti-methicillin-resistant Staphylococcus aureus (MRSA) evaluation of liquorice-decorated silver nanoparticles
In vitro and in vivo synergistic wound healing and anti-methicillin-resistant Staphylococcus aureus (MRSA) evaluation of liquorice-decorated silver nanoparticles
The multi-drug resistant Staph. aureus strain, Methicillin-resistant Staphylococcus aureus (MRSA), is an emerging pathogen...
Persistence of resistance: a panel data analysis of the effect of antibiotic usage on the prevalence of resistance
Persistence of resistance: a panel data analysis of the effect of antibiotic usage on the prevalence of resistance
The use of antibiotics promotes the emergence of resistant bacteria in the patient and the environment. The extent of this...
A novel biologically active xylaphenoside from the endophytic fungus Xylaria CGMCC No.5410
A novel biologically active xylaphenoside from the endophytic fungus Xylaria CGMCC No.5410
A novel 3,4-dihydroisocoumarin glycoside (1) was obtained from the culture of endophytic fungal Xylaria CGMCC No.5410 from...
In vitro antibacterial effects of combination of ciprofloxacin with compounds isolated from Streptomyces luteireticuli NIIST-D75
In vitro antibacterial effects of combination of ciprofloxacin with compounds isolated from Streptomyces luteireticuli NIIST-D75
Three phenazines, 1-methoxyphenazine (1), methyl-6-methoxyphenazine-1-carboxylate (2), 1,6-dimethoxyphenazine (4), and a 2...
Molecular docking simulation, drug-likeness assessment, and pharmacokinetic study of some cephalosporin analogues against a penicillin-binding protein of Salmonella typhimurium
Molecular docking simulation, drug-likeness assessment, and pharmacokinetic study of some cephalosporin analogues against a penicillin-binding protein of Salmonella typhimurium
In pursuit of novel antibiotics that could curb the growing trend of multidrug resistance by Salmonella typhimurium, a dat...
Nocardiopsis changdeensis sp. nov., an endophytic actinomycete isolated from the roots of Eucommia ulmoides Oliv
Nocardiopsis changdeensis sp. nov., an endophytic actinomycete isolated from the roots of Eucommia ulmoides Oliv
Strain Mg02T was isolated from roots of Eucommia ulmoides Oliv. collected from Changde City, Hunan Province, China. Strain...
Phaeolschidin F, a new symmetrical bis(styrylpyrone) derivative with redox-catalyzing activity from the mushroom Gymnopilus aeruginosus (order Agaricales)
Phaeolschidin F, a new symmetrical bis(styrylpyrone) derivative with redox-catalyzing activity from the mushroom Gymnopilus aeruginosus (order Agaricales)
Phaeolschidin F (1) was isolated from fruiting bodies of the bitter and toxic mushroom Gymnopilus aeruginosus. Structure a...
Impact of short chain fatty acids (SCFAs) on antimicrobial activity of new β-lactam/β-lactamase inhibitor combinations and on virulence of Escherichia coli isolates
Impact of short chain fatty acids (SCFAs) on antimicrobial activity of new β-lactam/β-lactamase inhibitor combinations and on virulence of Escherichia coli isolates
In a healthy gut microbiota, short chain fatty acids (SCFAs) are produced. The antibacterial action of SCFAs against intes...
Genome mining and chemical characterization of a new cyclic lipopeptide associated with MDN-0066 from Pseudomonas moraviensis HN2 cultured in a valine-rich medium
Genome mining and chemical characterization of a new cyclic lipopeptide associated with MDN-0066 from Pseudomonas moraviensis HN2 cultured in a valine-rich medium
A new cyclic lipopeptide (CLP) MDN-0066-β (1) and MDN-0066 (2) were isolated and characterized from the bacterial cul...
Substance Index for Volume75
Actinopolymorphol E, F 619Allobetulin, 3β-amino-28-oxo 258Anthraquinone, 1,4,6-trihydroxy-8-(2′R-hydro-xy...
Author Index for Volume 75
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Drug repurposing strategy II: from approved drugs to agri-fungicide leads
Drug repurposing strategy II: from approved drugs to agri-fungicide leads
Epidemic diseases of crops caused by fungi deeply affected the course of human history and processed a major restriction o...
Impact of surfactants and other body fluids on in vitro activity of a novel β-lactamase inhibitor enmetazobactam in combination with cefepime against clinical isolates of Klebsiella pneumoniae
Impact of surfactants and other body fluids on in vitro activity of a novel β-lactamase inhibitor enmetazobactam in combination with cefepime against clinical isolates of Klebsiella pneumoniae
Surfactants might impact treatment of lower respiratory tract infections. Moreover, other body fluids, such as urine or se...
Sulfoxanthicillin from the deep-sea derived Penicillium sp. SCSIO sof101: an antimicrobial compound against Gram-positive and -negative pathogens
Sulfoxanthicillin from the deep-sea derived Penicillium sp. SCSIO sof101: an antimicrobial compound against Gram-positive and -negative pathogens
Natural products along with their analogs have been intensively explored for their antimicrobial potential against ‘...
Alkyl aromatic derivatives from the endophytic fungus Cytospora rhizophorae
Alkyl aromatic derivatives from the endophytic fungus Cytospora rhizophorae
Two new alkylresorcinols named herein 5’-methoxy-integracins A-B (1-2), two new monomeric alkyl aromatic derivatives...
Correction: The occurrence of antibiotic resistance genes in the microbiota of yak, beef and dairy cattle characterized by a metagenomic approach
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Streptomyces pacificus sp. nov., a novel spongiicolazolicin-producing actinomycete isolated from a coastal sediment
Streptomyces pacificus sp. nov., a novel spongiicolazolicin-producing actinomycete isolated from a coastal sediment
A polyphasic approach was used to determine the taxonomic position of a marine actinomycete, designated isolate CWH03T, wh...
Four new chromone derivatives from the Arctic fungus Phoma muscivora CPCC 401424 and their antiviral activities
Four new chromone derivatives from the Arctic fungus Phoma muscivora CPCC 401424 and their antiviral activities
The crude extract of the Arctic fungus Phoma muscivora CPCC 401424 displayed anti-influenza A virus activities which led u...
New meroterpenoids from a soil-derived fungus Penicillium sp. SSW03M2 GY and their anti-virulence activity
New meroterpenoids from a soil-derived fungus Penicillium sp. SSW03M2 GY and their anti-virulence activity
Two new berkeley meroterpenoids (1 and 2), along with seven known compounds (3‒9) were isolated from a fungus, Penic...
Isolation, structural determination, and antiviral activities of metabolites from vanitaracin A-producing Talaromyces sp.
Isolation, structural determination, and antiviral activities of metabolites from vanitaracin A-producing Talaromyces sp.
Vanitaracin A, an anti-hepatitis B virus polyketide, has been previously isolated from Talaromyces sp. In the present stud...
Winners of the 2021 JA Ōmura Awards for excellence
Winners of the 2021 JA Ōmura Awards for excellence
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional ...
New piericidin rhamnosides as potentiators of amphotericin B activity against Candida albicans produced by actinomycete strain TMPU-A0287
New piericidin rhamnosides as potentiators of amphotericin B activity against Candida albicans produced by actinomycete strain TMPU-A0287
Four new piericidin rhamnosides (2, 4–6) together with three known piericidins (1, 3, 7) were isolated from the cult...
1-(6-Methylsalicyloyl)glycerol from stony coral-derived Micromonospora sp.
1-(6-Methylsalicyloyl)glycerol from stony coral-derived Micromonospora sp.
A new natural product, 1-(6-methylsalicyloyl)glycerol (1) was isolated from the culture extract of the stony coral-derived...
阅读更多
format_indent_increase