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Haneummycin, a new 22-membered macrolide lactam antibiotic, produced by marine-derived Streptomyces sp. KM77-8
Haneummycin, a new 22-membered macrolide lactam antibiotic, produced by marine-derived Streptomyces sp. KM77-8
A new antibiotic named haneummycin (1) was isolated from a culture broth of marine-derived Streptomyces sp. KM77-8 by solv...
Botryorhodines K and L, two new cytotoxic depsidones from a fungus of the genus Arcopilus
Botryorhodines K and L, two new cytotoxic depsidones from a fungus of the genus Arcopilus
Botryorhodines K (1) and L (2), two new depsidone derivatives, along with one known metabolite, 4-O-demethylbarbatic acid ...
Aspects for development of novel antibacterial medicines using a vitamin D3 decomposition product in Helicobacter pylori infection
Aspects for development of novel antibacterial medicines using a vitamin D3 decomposition product in Helicobacter pylori infection
A previous study by our group demonstrated that a vitamin D3 decomposition product (VDP1) acts as the selective bactericid...
Antibiotic stewardship programs should include disinfectants and biocides
Rising antimicrobial resistance (AMR) is considered a public health emergency since the practice of moder...
In vitro activity of cefiderocol in combination with new β-lactam/β-lactamase inhibitor combinations (βL-βLICs) against multidrug resistant KPC-producing Klebsiella pneumoniae
In vitro activity of cefiderocol in combination with new β-lactam/β-lactamase inhibitor combinations (βL-βLICs) against multidrug resistant KPC-producing Klebsiella pneumoniae
Gaibani P, Giani T, Bovo F, Lonbardo D, Amadesi S, Lazzarotto T, et al. Resistance to ceftazidime/avibactam, meropenem/vab...
(±) Pestalactone D and pestapyrone F, two new isocoumarins from an endolichenic Pestalotiopsis rhododendri
(±) Pestalactone D and pestapyrone F, two new isocoumarins from an endolichenic Pestalotiopsis rhododendri
Three isocoumarins, including two new compounds, (±) pestalactone D (1) and pestapyrone F (2), as well as one known c...
Mechanisms of emerging resistance associated with non-antibiotic antimicrobial agents: a state-of-the-art review
Mechanisms of emerging resistance associated with non-antibiotic antimicrobial agents: a state-of-the-art review
Although the development of resistance by microorganisms to antimicrobial drugs has been recognized as a global public hea...
Saccharopolyspora oryzae sp. nov., isolated from rhizosphere soil of the wild rice species Oryza rufipogon
Saccharopolyspora oryzae sp. nov., isolated from rhizosphere soil of the wild rice species Oryza rufipogon
A novel actinobacterium, designated as strain WRP15-2T, was isolated from rhizosphere soil of rice plant (Oryza rufipogon)...
New potentiators of amphotericin B activity, shodoamides A to C produced by Pseudophialophora sp. BF-0158
New potentiators of amphotericin B activity, shodoamides A to C produced by Pseudophialophora sp. BF-0158
During our screening program for new potentiators of amphotericin B activity against Candida albicans, shodoamides A to C ...
Emblestatin: a new peptide antibiotic from Embleya scabrispora K20-0267
Emblestatin: a new peptide antibiotic from Embleya scabrispora K20-0267
A new peptide, emblestatin (1), was discovered from a culture broth of Embleya scabrispora K20-0267. This strain was isola...
Iseoic acids and bisiseoate: three new naphthohydroquinone/naphthoquinone-class metabolites from a coral-derived Streptomyces
Iseoic acids and bisiseoate: three new naphthohydroquinone/naphthoquinone-class metabolites from a coral-derived Streptomyces
Two new naphthohydroquinone derivatives designated iseoic acids A (1) and B (2) and a new symmetrical glycerol bisester of...
Rubiflavin G, photorubiflavin G, and photorubiflavin E: Novel pluramycin derivatives from Streptomyces sp. W2061 and their anticancer activity against breast cancer cells
Rubiflavin G, photorubiflavin G, and photorubiflavin E: Novel pluramycin derivatives from Streptomyces sp. W2061 and their anticancer activity against breast cancer cells
The pluramycin family of antibiotics comprises angucycline compounds derived from actinomycetes that possess anticancer an...
Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972
Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972
There are six new phthalide derivatives Verbalide A ~ F (1–6) together with another known derivative (7)...
Rapid detection of fluoroquinolone resistance in Mycobacterium tuberculosis using a novel multienzyme isothermal rapid assay
Rapid detection of fluoroquinolone resistance in Mycobacterium tuberculosis using a novel multienzyme isothermal rapid assay
Simple, rapid, and accurate detection of Fluoroquinolone (FQ) resistance is essential for early initiation of appropriate ...
Amamine, an isoquinoline alkaloid from the Kitasatospora sp. HGTA304
Amamine, an isoquinoline alkaloid from the Kitasatospora sp. HGTA304
Amamine (1), a new isoquinoline alkaloid, was isolated from the culture extract of an actinomycete Kitasatospora sp. HGTA3...
Antibacterial and antibiofilm activities of ZIF-67
Antibacterial and antibiofilm activities of ZIF-67
Currently, antibiotic-resistant bacteria represent a serious threat to public health worldwide. Biofilm formation potentia...
Isolation of two new stereochemical variants of streptophenazine by cocultivation of Streptomyces NIIST-D31, Streptomyces NIIST-D47, and Streptomyces NIIST-D63 strains in 3C2 combinations
Isolation of two new stereochemical variants of streptophenazine by cocultivation of Streptomyces NIIST-D31, Streptomyces NIIST-D47, and Streptomyces NIIST-D63 strains in 3C2 combinations
Cocultivation of combinations of Streptomyces species isolated from the same soil was explored to isolate novel secondary ...
Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-l-lysine production in Streptomyces albulus
Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-l-lysine production in Streptomyces albulus
Streptomyces albulus NBRC14147 produces a homopoly(amino acid), ε-poly-l-lysine (ε-PL). Due to its antibiotic ac...
Impact of soil supplemented with pig manure on the abundance of antibiotic resistant bacteria and their associated genes
Impact of soil supplemented with pig manure on the abundance of antibiotic resistant bacteria and their associated genes
This study was conducted to evaluate the abundance of antibiotic resistant bacteria and their resistance genes from agricu...
Antibiotics in the clinical pipeline as of December 2022
Antibiotics in the clinical pipeline as of December 2022
The need for new antibacterial drugs to treat the increasing global prevalence of drug-resistant bacterial infections has ...
Avidumicin, a novel cyclic bacteriocin, produced by Cutibacterium avidum shows anti-Cutibacterium acnes activity
Avidumicin, a novel cyclic bacteriocin, produced by Cutibacterium avidum shows anti-Cutibacterium acnes activity
The prevalence of antimicrobial-resistant Cutibacterium acnes in acne patients has increased owing to inappropriate antimi...
Rubensteroid A, a new steroid with antibacterial activity from Penicillium rubens AS-130
Rubensteroid A, a new steroid with antibacterial activity from Penicillium rubens AS-130
A new steroid with strong antibacterial activity, rubensteroid A (1), along with its decarboxylic analogue, solitumergoste...
Correction: p-Terphenyl glucosides from the culture broth of Phlebiopsis castanea
Correction: p-Terphenyl glucosides from the culture broth of Phlebiopsis castanea
Authors and AffiliationsDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environ...
In vitro activity of ceftazidime/avibactam, imipenem/relebactam and meropenem/vaborbactam alone or in combination with polymyxin B against carbapenem resistant Acinetobacter baumannii
Nosocomial infection caused by Carbapenem-Resistant Acinetobacter baumannii (CR-A. baumannii) has become a challenge in cl...
A combination strategy of a semisynthetic macrolide, 5-O-mycaminosyltylonolide with polymyxin B nonapeptide for multi-drug resistance P. aeruginosa
A combination strategy of a semisynthetic macrolide, 5-O-mycaminosyltylonolide with polymyxin B nonapeptide for multi-drug resistance P. aeruginosa
The emergence and spread of antimicrobial resistant pathogens continue to threaten our ability to combat several infection...
Protaetiibacter mangrovi sp. nov., isolated from mangrove soil
Protaetiibacter mangrovi sp. nov., isolated from mangrove soil
A novel Gram-stain-positive, aerobic, non-flagellated and rod-shaped actinobacterium, designated 10F1B-8-1T, was isolated ...
Dactylides A−C, three new bioactive 22-membered macrolides produced by Dactylosporangium aurantiacum
Dactylides A−C, three new bioactive 22-membered macrolides produced by Dactylosporangium aurantiacum
Three new 22-membered polyol macrolides, dactylides A−C (1−3), were isolated from Dactylosporangium aurantiacu...
New secondary metabolites produced by Paraphoma radicina FB55 as potential antifungal agents
New secondary metabolites produced by Paraphoma radicina FB55 as potential antifungal agents
Microorganisms in specific environments are rich sources of bioactive natural products as they produce compounds that can ...
Development of a drug discovery approach from microbes with a special focus on isolation sources and taxonomy
Development of a drug discovery approach from microbes with a special focus on isolation sources and taxonomy
After the successful discoveries of numerous antibiotics from microorganisms, frequent reisolation of known compounds beco...
The potential target of bithionol against Staphylococcus aureus: design, synthesis and application of biotinylated probes Bio-A2
The potential target of bithionol against Staphylococcus aureus: design, synthesis and application of biotinylated probes Bio-A2
This study aims to explore the potential targets of bithionol in Staphylococcus aureus.The four bithionol biotinylated pro...
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