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Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Osimertinib has emerged as the standard first-line treatment for advanced non-small cell lung cancer (NSCLC) with EGFR mut...
Foreign body granuloma caused by gauze fibers: a rare cause of chronic postoperative ileus following cytoreductive surgery for pseudomyxoma peritonei
Foreign body granuloma caused by gauze fibers: a rare cause of chronic postoperative ileus following cytoreductive surgery for pseudomyxoma peritonei
Foreign body granuloma (FBG) is an inflammatory reaction to an exogenous agent. This entity is well known on the cutaneous...
Mini-open periacetabular cementoplasty for periacetabular bone metastasis: a report of two cases
Mini-open periacetabular cementoplasty for periacetabular bone metastasis: a report of two cases
Bone metastasis in the periacetabular region usually causes severe pain and functional disability. Some surgical procedure...
Ovarian carcinosarcoma of heterologous type occurring in an endometriotic cyst with 3-year recurrence-free survival: a case report and literature review
Ovarian carcinosarcoma of heterologous type occurring in an endometriotic cyst with 3-year recurrence-free survival: a case report and literature review
A 41-year-old premenopausal woman presented to our hospital with lower abdominal distention and epigastralgia. An ovarian ...
Prostate ductal adenocarcinoma with MLH1 copy number loss, microsatellite instability high and BRCA2 mutation
Prostate ductal adenocarcinoma with MLH1 copy number loss, microsatellite instability high and BRCA2 mutation
Mismatch repair deficiency (MMRd) or microsatellite instability high (MSI-H) is rare in prostate cancer and more frequentl...
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
First-bite syndrome (FBS) is manifested as acute and severe pain in the parotid region occurring at the first bite of a me...
SMARCA4-deficient epithelioid sarcoma revealed by comprehensive genomic profiling, leading to a notable response by nivolumab treatment
SMARCA4-deficient epithelioid sarcoma revealed by comprehensive genomic profiling, leading to a notable response by nivolumab treatment
A 50-year-old man presented with a bulky mass in the left thigh and was referred to our department. He showed an impaired ...
A case of selpercatinib treatment for anaplastic thyroid carcinoma resulting in abscess formation
A case of selpercatinib treatment for anaplastic thyroid carcinoma resulting in abscess formation
Rearranged during transfection (RET) gene abnormality is a driver gene mutation that causes thyroid cancer, and selpercati...
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disorder characterized by refractory recurrent epistaxis and...
Radiotherapy for cytokeratin-positive interstitial reticulum cell (CIRC) tumor on epicardium: a case report
Radiotherapy for cytokeratin-positive interstitial reticulum cell (CIRC) tumor on epicardium: a case report
Cytokeratin-positive interstitial reticulum cell (CIRC) tumor is an extremely rare malignant neoplasm and a subtype of fib...
Ponatinib and prednisolone induce sustained remission in a relapsed case of mixed-phenotype acute leukemia with BCR::ABL1 fusion intolerant to dasatinib
Ponatinib and prednisolone induce sustained remission in a relapsed case of mixed-phenotype acute leukemia with BCR::ABL1 fusion intolerant to dasatinib
Mixed-phenotype acute leukemia (MPAL) with BCR::ABL1 fusion is a rare leukemia subtype exhibiting both myeloid and lymphoi...
A case of gastritis caused by immune checkpoint inhibitor treated with infliximab
A case of gastritis caused by immune checkpoint inhibitor treated with infliximab
Immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs) in various organs. Herein, we present ...
Intraventricular ganglioneuroblastoma: an uncommon location for a rare tumour in a young adult with review of literature
Intraventricular ganglioneuroblastoma: an uncommon location for a rare tumour in a young adult with review of literature
Ganglioneuroblastoma (GNB) is a rare tumour of neuroectodermal origin consisting of a varying proportion of neuroblasts an...
SMARCA4-deficient uterine tumors in young women: response to immune checkpoint inhibitors
SMARCA4-deficient uterine tumors in young women: response to immune checkpoint inhibitors
SMARCA4-deficient tumors have been reported in various organs and are associated with a poor prognosis. SMARCA4-deficient ...
A case of grade1 follicular lymphoma diagnosed by laparoscopic lymph node resection: differentiating from late lymph node recurrence of endometrial cancer
A case of grade1 follicular lymphoma diagnosed by laparoscopic lymph node resection: differentiating from late lymph node recurrence of endometrial cancer
Follicular lymphoma is a common hematologic malignancy; however, it is less common among all malignant diseases and is dif...
A case report of mucinous borderline ovarian tumor with recurrence as invasive carcinoma with high copy number alterations
A case report of mucinous borderline ovarian tumor with recurrence as invasive carcinoma with high copy number alterations
Mucinous borderline ovarian tumors (MBOTs) have a very low recurrence rate and a good prognosis, especially in the early s...
Effectiveness of trastuzumab deruxtecan rechallenge in a patient with HER2-positive metastatic breast cancer: a case report
Effectiveness of trastuzumab deruxtecan rechallenge in a patient with HER2-positive metastatic breast cancer: a case report
Trastuzumab deruxtecan (T-DXd), a high-payload antibody drug conjugate, has been reported to exert potent antitumor effect...
Secondary spontaneous pneumothorax during chemotherapy with bevacizumab for cervical cancer: a case report and literature review
Secondary spontaneous pneumothorax during chemotherapy with bevacizumab for cervical cancer: a case report and literature review
Secondary spontaneous pneumothorax (SSP) due to bevacizumab has been reported in other malignancies but not in cervical ca...
Immune checkpoint inhibitor-associated sick sinus syndrome and cardiogenic shock
Immune checkpoint inhibitor-associated sick sinus syndrome and cardiogenic shock
Immune checkpoint inhibitors (ICI) represent a major advance in the treatment of cancer. Most studies of ICI have underest...
Limb salvage using radical combined hyperthermia and radiotherapy for myxofibrosarcoma of the lower leg in an elderly patient
Limb salvage using radical combined hyperthermia and radiotherapy for myxofibrosarcoma of the lower leg in an elderly patient
Soft tissue sarcomas account for only 1.5% of malignant tumors in adults and are therefore challenging to treat. We presen...
A case of pagetoid spread of urothelial carcinoma with notable reduction achieved through enfortumab vedotin, resulting in complete surgical resection
A case of pagetoid spread of urothelial carcinoma with notable reduction achieved through enfortumab vedotin, resulting in complete surgical resection
Secondary extramammary Paget’s disease is a rare condition associated with the contiguous extension of tumor cells f...
Carcinoma esophagus with small bowel metastasis: a case report with review of literature
Carcinoma esophagus with small bowel metastasis: a case report with review of literature
Small intestinal metastasis is extremely rare and only 13 cases have been reported till date and almost all such patients ...
Complete response using the EZH2 inhibitor tazemetostat against multiple relapsed follicular lymphoma in the leukemic phase
Complete response using the EZH2 inhibitor tazemetostat against multiple relapsed follicular lymphoma in the leukemic phase
Though multiple relapses and serial shortening of remission is one of the characteristics of follicular lymphoma (FL), sta...
Radiation hepatitis after postmastectomy radiation therapy for early breast cancer: difficult to differentiate from drug-induced liver injury caused by abemaciclib
Radiation hepatitis after postmastectomy radiation therapy for early breast cancer: difficult to differentiate from drug-induced liver injury caused by abemaciclib
Abemaciclib (ABM) is recommended for adjuvant endocrine therapy in hormone receptor-positive, human epidermal growth facto...
Fertility preservation in men with hypogonadotropic hypogonadism secondary to germinoma: two cases of gonadotropin replacement therapy before induction of anticancer chemotherapy
Fertility preservation in men with hypogonadotropic hypogonadism secondary to germinoma: two cases of gonadotropin replacement therapy before induction of anticancer chemotherapy
Hypogonadotropic hypogonadism can be caused by brain tumors. For a malignancy such as a germ cell tumor, chemotherapy comb...
High likelihood of BRCA2 reversion mutation in pancreatic cancer post-platinum-based chemotherapy: a case study
High likelihood of BRCA2 reversion mutation in pancreatic cancer post-platinum-based chemotherapy: a case study
A 54-year-old man with resectable pancreatic cancer and abnormally high levels of carbohydrate antigen 19–9 (CA19-9)...
First report of retroperitoneal rhabdomyosarcoma treated with space-making particle therapy for preservation of renal function
First report of retroperitoneal rhabdomyosarcoma treated with space-making particle therapy for preservation of renal function
Space-making particle therapy, which consists of surgical placement of a spacer followed by particle therapy, has become a...
Breast mucoepidermoid carcinoma with a rare CRTC3–MAML2 fusion
Breast mucoepidermoid carcinoma with a rare CRTC3–MAML2 fusion
Mucoepidermoid carcinoma is the most prevalent malignancy in the salivary gland and is sporadic in the breast. Here, we re...
Primary mediastinal choriocarcinoma in a woman treated with VIP therapy instead of BEP therapy for the prevention of postoperative acute respiratory distress syndrome
Primary mediastinal choriocarcinoma in a woman treated with VIP therapy instead of BEP therapy for the prevention of postoperative acute respiratory distress syndrome
Primary mediastinal germ cell tumor (PMGCT) is an extragonadal germ cell tumor (GCT) that is classified as a poor-prognosi...
Cerebral arterial air embolism after esophageal stenting for recurrence of gastroesophageal junction cancer: a case report
Cerebral arterial air embolism after esophageal stenting for recurrence of gastroesophageal junction cancer: a case report
Cerebral arterial air embolism (CAE) is a rare complication after esophageal stenting, but it can be life-threatening. It ...
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