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BRAF-mutant microsatellite-stable rectal cancer with acquired KRAS mutation leading to drug resistance in liver metastasis
BRAF-mutant microsatellite-stable rectal cancer with acquired KRAS mutation leading to drug resistance in liver metastasis
BRAF-mutant microsatellite-stable colorectal cancer (CRC), metastasized to distant sites, is associated with a poor progno...
Aggressive variant prostate cancer with multiple subcutaneous metastases: a case report
Aggressive variant prostate cancer with multiple subcutaneous metastases: a case report
A 71-year-old man with bone metastasis of hormone-sensitive prostate cancer was treated with androgen deprivation therapy ...
Multiple endocrine neoplasia type 1 with MEN1 variant of unknown significance, in a patient after the diagnosed of pancreatic neuroendocrine neoplasia
Multiple endocrine neoplasia type 1 with MEN1 variant of unknown significance, in a patient after the diagnosed of pancreatic neuroendocrine neoplasia
Duodenopancreatic neuroendocrine neoplasia (DP-NEN) is in approximately 10% of cases of multiple endocrine neoplasia type ...
Significant improvement in paraneoplastic neurological syndromes without identifiable anti-neural antibodies in patients with breast cancer after breast surgery
Significant improvement in paraneoplastic neurological syndromes without identifiable anti-neural antibodies in patients with breast cancer after breast surgery
Paraneoplastic neurological syndromes (PNS) are neurological disorders that occur in close association with tumors without...
Successful treatment of pediatric patients with high-grade gliomas featuring leptomeningeal metastases by targeting BRAF V600E mutations with dabrafenib plus trametinib: two illustrative cases
Successful treatment of pediatric patients with high-grade gliomas featuring leptomeningeal metastases by targeting BRAF V600E mutations with dabrafenib plus trametinib: two illustrative cases
A combination of BRAF and MEK inhibitors is reported to be effective for gliomas with the BRAF V600E mutation; however, it...
A challenging case of an adamantinoma of fibula with soft tissue mass harboring distinct histopathology
A challenging case of an adamantinoma of fibula with soft tissue mass harboring distinct histopathology
We present a case of adamantinoma that originated from the fibula and had a large soft tissue component measuring approxim...
Disseminated AIDS-associated Kaposi sarcoma without cutaneous involvement: a case report and review of literature
Disseminated AIDS-associated Kaposi sarcoma without cutaneous involvement: a case report and review of literature
Disseminated AIDS-associated Kaposi sarcoma (KS) without cutaneous lesions is rare and can present in varying ways. Diagno...
Definitive chemoradiotherapy for a patient with anal cancer after renal transplantation
Definitive chemoradiotherapy for a patient with anal cancer after renal transplantation
Patients after renal transplantation are susceptible to secondary malignancies, including anal squamous cell carcinoma. Ch...
A case of treatment-resistant advanced gastric cancer with FGFR2 gene alteration successfully treated with pemigatinib
A case of treatment-resistant advanced gastric cancer with FGFR2 gene alteration successfully treated with pemigatinib
Comprehensive genome profiling (CGP) is expected to widen the scope of cancer drug options by identifying the genes involv...
Remarkable response to capmatinib in a patient with intrahepatic cholangiocarcinoma harboring TFG-MET fusion
Remarkable response to capmatinib in a patient with intrahepatic cholangiocarcinoma harboring TFG-MET fusion
Dysregulation of mesenchymal-epithelial transition factor (MET) gene due to amplification, mutation, and fusion has been r...
EGFR-mutated lung adenocarcinoma with choroidal oligometastasis during treatment with gefitinib: a case report
EGFR-mutated lung adenocarcinoma with choroidal oligometastasis during treatment with gefitinib: a case report
The patient was a 74-year-old woman who was diagnosed with lung adenocarcinoma, clinical Stage IIIA. Induction chemoradiat...
Successful pre-surgical treatment with carboplatin and gemcitabine chemotherapy for a patient with muscle-invasive bladder cancer and severe renal dysfunction
Successful pre-surgical treatment with carboplatin and gemcitabine chemotherapy for a patient with muscle-invasive bladder cancer and severe renal dysfunction
Radical cystectomy is the standard treatment for muscle-invasive bladder cancer, and pre-surgical treatment can improve su...
Suction thrombectomy of a uterine carcinosarcoma tumor thrombus extending into the IVC and right atrium
Suction thrombectomy of a uterine carcinosarcoma tumor thrombus extending into the IVC and right atrium
Uterine carcinosarcoma is a rare, aggressive tumor with several cases in the literature reporting cardiac tumor thrombus i...
Spot scanning proton therapy for unresectable bulky retroperitoneal dedifferentiated liposarcoma: a case report
Spot scanning proton therapy for unresectable bulky retroperitoneal dedifferentiated liposarcoma: a case report
The development of effective treatment strategies for unresectable retroperitoneal sarcoma is desirable. Herein, we sugges...
Capecitabine and oxaliplatin induced Steven–Johnson syndrome following nivolumab in a patient of metastatic esophageal carcinoma
Capecitabine and oxaliplatin induced Steven–Johnson syndrome following nivolumab in a patient of metastatic esophageal carcinoma
Stevens–Johnson syndrome presents as mucocutaneous blistering and sloughing, which may follow a devastating clinical...
Complete reduction surgery of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy
Complete reduction surgery of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy
Adult granulosa cell tumors are rare, accounting for only 3–5% of all ovarian tumors. Adult granulosa cell tumors ha...
A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab
A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab
Pancreatic injury is a rare, but noted complication of nephrectomy. We report a case involving a 56-year-old man who prese...
Anthracycline-based hepatic arterial infusion chemotherapy achieved 17 months of disease regression in a patient with breast cancer liver metastases resistant to multiple systemic chemotherapies
Anthracycline-based hepatic arterial infusion chemotherapy achieved 17 months of disease regression in a patient with breast cancer liver metastases resistant to multiple systemic chemotherapies
Hepatic arterial infusion chemotherapy (HAIC) for liver metastases (LMs) from breast cancer is not a standard of care, but...
A case of hereditary breast and ovarian cancer syndrome of initially presented as cancer of unknown primary with lymph node metastases unveiled by genetic analysis
A case of hereditary breast and ovarian cancer syndrome of initially presented as cancer of unknown primary with lymph node metastases unveiled by genetic analysis
Cancer of unknown primary (CUP) is a heterogeneous disease concept involving various malignant tumors. Understanding its p...
Utility of articulating instruments as an alternative to robotic devices in laparoscopic right hemicolectomy
Utility of articulating instruments as an alternative to robotic devices in laparoscopic right hemicolectomy
Laparoscopic complete mesocolic excision with central vessel ligation has been widely accepted for its oncological benefit...
Primary signet-ring cell carcinoma of the bladder treated with laparoscopic radical cystectomy: a case report
Primary signet-ring cell carcinoma of the bladder treated with laparoscopic radical cystectomy: a case report
Primary bladder adenocarcinomas comprise 0.5–2% of all epithelial bladder neoplasms. Of these, primary signet-ring c...
Giant retroperitoneal myolipoma mimicking liposarcoma: report of a resected case and review of the literature
Giant retroperitoneal myolipoma mimicking liposarcoma: report of a resected case and review of the literature
Myolipomas are rare tumors that are often difficult to differentiate from liposarcoma. Herein, we report a case of resecte...
Intratumoral metastasis of sigmoid colon cancer to chromophobe renal cell carcinoma: a case report
Intratumoral metastasis of sigmoid colon cancer to chromophobe renal cell carcinoma: a case report
We herein report an extremely rare case of intratumoral metastasis of colon cancer to chromophobe renal cell carcinoma. A ...
Rapid tumor progression complicated with liver abscess in a patient with gastric cancer receiving nivolumab therapy
Rapid tumor progression complicated with liver abscess in a patient with gastric cancer receiving nivolumab therapy
Immune checkpoint inhibitors have been approved for treating various cancer types. However, several studies reported rapid...
Multidisciplinary treatment for small cell carcinoma of the bladder: a case report
Multidisciplinary treatment for small cell carcinoma of the bladder: a case report
Small cell carcinoma (SCC) of the urinary bladder is a rare and highly aggressive subtype of bladder cancer. Most cases ar...
Coexistence of ovarian cancer and peritoneal tuberculosis: a case report
Coexistence of ovarian cancer and peritoneal tuberculosis: a case report
Peritoneal tuberculosis (TB) is known to mimic advanced ovarian cancer. In this case report, we describe a unique case of ...
Remarkable remission of symptomatic dermatomyositis after curative breast cancer surgery
Remarkable remission of symptomatic dermatomyositis after curative breast cancer surgery
Dermatomyositis (DM) is an autoimmune disease that causes proximal muscle weakness in the extremities leading to severe im...
Challenges in the management of Turner syndrome with Y chromosome material: a case report of prophylactic gonadectomy revealing dysgerminoma
Challenges in the management of Turner syndrome with Y chromosome material: a case report of prophylactic gonadectomy revealing dysgerminoma
Turner syndrome (TS) patients with Y chromosome material face an increased risk of gonadal germ cell tumors (GCTs). This c...
Response to capmatinib in a patient with neuroendocrine carcinoma of the gallbladder origin harboring MET amplification
Response to capmatinib in a patient with neuroendocrine carcinoma of the gallbladder origin harboring MET amplification
Neuroendocrine carcinoma (NEC) of the gallbladder origin is particularly rare, accounting for only 0.38% of primary malign...
Significant reduction in burden of metastatic disease by intermittent docetaxel therapy in a patient with castration-resistant prostate cancer
Significant reduction in burden of metastatic disease by intermittent docetaxel therapy in a patient with castration-resistant prostate cancer
Intermittent docetaxel therapy (IDT) is rarely used nowadays as a treatment option for men with metastatic castration-resi...
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