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Biomolecules, Vol. 12, Pages 1795: Acyl-Lipid Δ6-Desaturase May Act as a First FAD in Cyanobacteria
Biomolecules, Vol. 12, Pages 1795: Acyl-Lipid Δ6-Desaturase May Act as a First FAD in Cyanobacteria
Fatty acid desaturases (FADs) play important roles in various metabolic and adaptive pathways in all living organisms. The...
Biomolecules, Vol. 12, Pages 1798: Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold
Biomolecules, Vol. 12, Pages 1798: Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold
RNase Y is a crucial component of genetic translation, acting as the key enzyme initiating mRNA decay in many Gram-positiv...
Biomolecules, Vol. 12, Pages 1805: Alteration of Cellular Energy Metabolism through LPAR2-Axin2 Axis in Gastric Cancer
Biomolecules, Vol. 12, Pages 1805: Alteration of Cellular Energy Metabolism through LPAR2-Axin2 Axis in Gastric Cancer
Lysophosphatidic acid (LPA), a multifunctional endogenous phospholipid, plays a vital role in cellular homeostasis and the...
Biomolecules, Vol. 12, Pages 1804: Role of Pyroptosis in Intervertebral Disc Degeneration and Its Therapeutic Implications
Biomolecules, Vol. 12, Pages 1804: Role of Pyroptosis in Intervertebral Disc Degeneration and Its Therapeutic Implications
Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process, is predominantly associated...
Biomolecules, Vol. 12, Pages 1802: New Insights into lncRNAs in Aβ Cascade Hypothesis of Alzheimer’s Disease
Biomolecules, Vol. 12, Pages 1802: New Insights into lncRNAs in Aβ Cascade Hypothesis of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of dementia, but its pathogenesis is not fully understood, and ...
Biomolecules, Vol. 12, Pages 1779: SNARE Modulators and SNARE Mimetic Peptides
Biomolecules, Vol. 12, Pages 1779: SNARE Modulators and SNARE Mimetic Peptides
The soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptor (SNARE) proteins play a central rol...
Biomolecules, Vol. 12, Pages 1777: Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer
Biomolecules, Vol. 12, Pages 1777: Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer
Previously, we reported that MTH1 inhibitors TH588 and TH1579 selectively induce oxidative damage and kill Ras-expressing ...
Biomolecules, Vol. 12, Pages 1784: Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective
Biomolecules, Vol. 12, Pages 1784: Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective
Benzodiazepines (BZDs) are a class of widely prescribed psychotropic drugs that target GABAA receptors (GABAARs) to tune i...
Biomolecules, Vol. 12, Pages 1785: PDX-1: A Promising Therapeutic Target to Reverse Diabetes
Biomolecules, Vol. 12, Pages 1785: PDX-1: A Promising Therapeutic Target to Reverse Diabetes
The pancreatic duodenum homeobox-1 (PDX-1) is a transcription factor encoded by a Hox-like homeodomain gene that plays a c...
Biomolecules, Vol. 12, Pages 1792: Heparan Sulfate Proteoglycans in Tauopathy
Biomolecules, Vol. 12, Pages 1792: Heparan Sulfate Proteoglycans in Tauopathy
Tauopathies are a class of neurodegenerative diseases, including Alzheimer’s disease, and are characterized by i...
Biomolecules, Vol. 12, Pages 1791: Pseudocholinesterase as a Biomarker for Untreated Wilson’s Disease
Biomolecules, Vol. 12, Pages 1791: Pseudocholinesterase as a Biomarker for Untreated Wilson’s Disease
The aim of this study was to demonstrate that pseudocholinesterase (CHE) serum level is a useful diagnostic biomarker for ...
Biomolecules, Vol. 12, Pages 1789: A Large-Scale High-Throughput Screen for Modulators of SERCA Activity
Biomolecules, Vol. 12, Pages 1789: A Large-Scale High-Throughput Screen for Modulators of SERCA Activity
The sarco/endoplasmic reticulum Ca-ATPase (SERCA) is a P-type ion pump that transports Ca2+ from the cytosol into the endo...
Biomolecules, Vol. 12, Pages 1771: Sequence-Based Prediction of Protein Phase Separation: The Role of Beta-Pairing Propensity
Biomolecules, Vol. 12, Pages 1771: Sequence-Based Prediction of Protein Phase Separation: The Role of Beta-Pairing Propensity
The formation of droplets of bio-molecular condensates through liquid-liquid phase separation (LLPS) of their component pr...
Biomolecules, Vol. 12, Pages 1770: The Pathophysiological Significance of “Mitochondrial Ejection” from Cells
Biomolecules, Vol. 12, Pages 1770: The Pathophysiological Significance of “Mitochondrial Ejection” from Cells
Mitochondria have beneficial effects on cells by producing ATP and contributing to various biosynthetic procedures. On the...
Biomolecules, Vol. 12, Pages 1775: Ribose Intake as Food Integrator: Is It a Really Convenient Practice?
Biomolecules, Vol. 12, Pages 1775: Ribose Intake as Food Integrator: Is It a Really Convenient Practice?
Reports concerning the beneficial effects of D-ribose administration in cardiovascular and muscle stressful conditions has...
Biomolecules, Vol. 12, Pages 1762: Structural Studies of Piperine Inclusion Complexes in Native and Derivative β-Cyclodextrins
Biomolecules, Vol. 12, Pages 1762: Structural Studies of Piperine Inclusion Complexes in Native and Derivative β-Cyclodextrins
Piperine (PN), the primary pungent alkaloid in black pepper shows several biological activities such as antioxidant, antim...
Biomolecules, Vol. 12, Pages 1756: EIF4G1 Is a Potential Prognostic Biomarker of Breast Cancer
Biomolecules, Vol. 12, Pages 1756: EIF4G1 Is a Potential Prognostic Biomarker of Breast Cancer
Background: Breast cancer (BRCA) is one of the most common cancers in women worldwide and a leading cause of death from ma...
Biomolecules, Vol. 12, Pages 1755: Protein Targeting to Glycogen (PTG): A Promising Player in Glucose and Lipid Metabolism
Biomolecules, Vol. 12, Pages 1755: Protein Targeting to Glycogen (PTG): A Promising Player in Glucose and Lipid Metabolism
Protein phosphorylation and dephosphorylation are widely considered to be the key regulatory factors of cell function, and...