×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Pharmacology/Toxicology
10421
Global Medical University
3949
Allergy
1593
Anatomy & Morphology
1363
Andrology
414
Anesthesia & Intensive Care
1002
Anesthesiology
4445
Audiology & Speech-Language Pathology
307
Behavioral Sciences
83
Biochemical Research Methods
5486
Biochemistry & Molecular Biology
24950
Biodiversity Conservation
229
Biology
6698
Biophysics
6221
Biotechnology & Applied Microbiology
6757
Cardiac & Cardiovascular Systems
26215
Cardiovascular & Respiratory Systems
1208
Cell & Tissue Engineering
538
Cell Biology
9542
Chemistry, Analytical
3726
Chemistry, Applied
9575
Chemistry, Medicinal
7469
Chemistry, Multidisciplinary
16492
Clinical Immunology & Infectious Disease
373
Clinical Medicine
7963
Clinical Neurology
13620
Clinical Psychology & Psychiatry
932
Critical Care Medicine
2527
Dentistry, Oral Surgery & Medicine
10656
Dermatology
7083
Developmental Biology
6206
Ecology
617
Education, Scientific Disciplines
1520
Emergency Medicine
3209
Endocrinology, Metabolism & Nutrition
19598
Engineering, Biomedical
3072
Entomology
341
Environmental Medicine & Public Health
3841
Evolutionary Biology
211
Gastroenterology & Hepatology
9894
General & Internal Medicine
5787
Genetics & Heredity
12353
Geriatrics & Gerontology
4277
Gerontology
274
Health Care Sciences & Services
12879
Health Policy & Services
504
Hematology
4791
Immunology
20966
Infectious Diseases
11483
Integrative & Complementary Medicine
2089
Medical Ethics
901
Medical Informatics
1656
Medical Laboratory Technology
433
Medicine, General & Internal
38493
Medicine, Legal
362
Medicine, Research & Experimental
14428
Microbiology
19108
Mycology
0
Nanoscience & Nanotechnology
4179
Neuroimaging
1012
Neurology
3574
Neurosciences
32421
Nursing
7802
Nutrition & Dietetics
7102
Obstetrics & Gynecology
6767
Oncology
44160
Ophthalmology
7883
Optics
3197
Orthopedics
9293
Orthopedics, Rehabilitation & Sports Medicine
1395
Otolaryngology
1311
Otorhinolaryngology
4215
Parasitology
819
Pathology
4101
Pediatrics
17713
Peripheral Vascular Disease
3839
Pharmacology & Pharmacy
27599
Physiology
7867
Polymer Science
452
Primary Health Care
666
Psychiatry
15419
Psychology
4305
Psychology, Applied
68
Psychology, Biological
259
Psychology, Clinical
647
Psychology, Developmental
188
Psychology, Educational
107
Psychology, Experimental
93
Psychology, Mathematical
0
Psychology, Multidisciplinary
1357
Psychology, Psychoanalysis
41
Psychology, Social
86
Public Health & Health Care Science
1963
Public, Environmental & Occupational Health
23351
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
9979
Radiology, Nuclear Medicine & Medical Imaging
6722
Rehabilitation
2611
Remote Sensing
0
Reproductive Biology
2177
Reproductive Medicine
937
Research/Laboratory Medicine & Medical Technology
3158
Respiratory System
5899
Rheumatology
4677
Social Sciences, Biomedical
1068
Substance Abuse
2296
Surgery
27585
Toxicology
3696
Transplantation
804
Tropical Medicine
304
Urology & Nephrology
10639
Veterinary Sciences
35
Virology
1978
Zoology
0
渠道
FUNDAMENTAL & CLINICAL PHARMACOLOGY
100
ACTA PHARMACEUTICA SINICA B
605
ADVANCES IN THERAPY
663
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
276
BIOCHEMICAL PHARMACOLOGY
0
CURRENT OPINION IN PHARMACOLOGY
242
FRONTIERS IN PHARMACOLOGY
6246
JOURNAL OF CLINICAL LIPIDOLOGY
209
JOURNAL OF NEUROIMMUNE PHARMACOLOGY
86
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
291
AMERICAN JOURNAL OF THERAPEUTICS
64
ANTI-CANCER DRUGS
83
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
188
TOXICS
879
JOURNAL OF CLINICAL PHARMACOLOGY
150
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
339
SCI时时刷
search
全部
推荐
+
(‐)‐Epicatechin improves body composition of male rats descendant of obese mothers postnatally fed with a high‐fat diet
Abstract Background A combination of maternal obesity and high-fat diet (HFD) in offspring postnatal life has deleterious ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Optimization of application schedule of camphecene, a novel anti‐influenza compound, based on its pharmacokinetic characteristics
Abstract Background Due to high variability and rapid life cycle, influenza virus is able to develop drug resistance again...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
The synthesis and antineoplastic activities of thiaziridine, sulfidomethylphosphonium, dithiaphosphitane‐sulphide against the Ehrlich ascites carcinoma
Abstract Phosphonium compounds offer an attractive branch of research that chemists and biologists apply for producing man...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Clinical pharmacology: Current innovations and future challenges
Abstract Clinical pharmacology is the study of drugs in humans, from first-in-human studies to randomized controlled trial...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
High glucose upregulates PAR‐1 in SH‐SY5Y cells via deficiency of miR‐20a and miR‐190a
Abstract Thrombin activity enhancement and its receptor protease-activated receptor 1 (PAR-1) activation play vital roles ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Transforming growth factor‐β1 inhibits interleukin‐1β‐induced expression of inflammatory genes and Cathepsin S activity in human vascular smooth muscle cells
Abstract Objective and design This study investigated the opposite mechanisms by which IL-1β and TGF-β1 modula...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Hepatoprotective and therapeutic effects of resveratrol: A focus on anti‐inflammatory and anti‐ oxidative activities
Abstract Being the most essential organ in the body, the liver performs critical functions. Hepatic disorders, such as alc...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Safety concerns on the abuse potential of esketamine: multidimensional analysis of a new anti‐depressive drug on the market
Abstract Background Prominent features of esketamine (e.g., similar mechanism of action as ketamine and target population)...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Characterization of benzodiazepine misuse and comorbidities in patients with alcohol use disorder
Abstract Background Due to the frequent presence of anxious symptoms and sleep disorders, benzodiazepines (BZD) are often ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Characteristics, treatment patterns and residual cardiovascular risk of patients with a first acute myocardial infarction: A nationwide population‐based cohort study in Norway
Abstract Background There are few nationwide descriptive studies of longitudinal drug use and residual cardiovascular risk...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
High glucose up‐regulates PAR‐1 in SH‐SY5Y cells via deficiency of miR‐20a and miR‐190a
Abstract Thrombin activity enhancement and its receptor protease-activated receptor 1 (PAR-1) activation play vital roles ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Activation of spinal ephrin‐B3/EphBs signaling induces hyperalgesia through a PLP‐mediated mechanism
Abstract Ephrin B/EphB signaling pathway is involved in the regulation of pain caused by spinal cord injury. However, the ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Everolimus: A potential therapeutic agent targeting PI3K/Akt pathway in brain insulin system dysfunction and associated neurobehavioral deficits
Abstract Background It is well accepted that PI3k/Akt signaling pathway is a potential therapeutic window which regulates ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Chronic use of renin‐angiotensin‐aldosterone system blockers and mortality in COVID‐19: A multicenter prospective cohort and literature review
Abstract Aims The role of renin-angiotensin-aldosterone system (RAAS) blockers on the course of coronavirus disease 2019 (...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Short‐chain fatty acids increase intracellular calcium levels and enhance gut hormone release from STC‐1 cells via transient receptor potential Ankyrin1
Abstract Short-chain fatty acids (SCFAs), metabolites of colonic bacterial fermentation of complex carbohydrates, are clos...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Improvement of cognitive function, glucose and lipid homeostasis and serum osteocalcin levels by liraglutide in diabetic rats
Abstract Background Glucose and lipid abnormalities, oxidative stress (OXS) and reduced brain-derived neurotrophic factor ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Trends in the use of antihistamines with reference to drivers between 2015 and 2019: A population‐based registry analysis
Abstract Background First-generation antihistamines are considered driving-impairing medicines (DIM), while second- and th...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
What changes in prescription patterns of antiemetic medications in pregnant women in France?
Abstract Background In France, few data are available on the prescription patterns of antiemetic medications in pregnant w...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Effect of dapagliflozin and/or L‐arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor‐beta 1, autophagy, and apoptosis
Abstract Background Nitric oxide was reported to play an essential role in various physiological and pathological processe...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Kappa‐opioid receptor‐mediated thermal analgesia evoked by the intrathecal administration of the chemokine CCL1 in mice
Abstract Background The chemokine CC motif ligand 1 (CCL1) participates in immune cell recruitment and, as other chemokine...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Combination of human papillomaviruses L1 and L2 multiepitope constructs protects mice against tumor cells
Abstract Different types of cancer including cervical (>90%), anal (~88%), vaginal (~40%), and penile (~40%) cancers ar...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
The numerical probability of carcinogenicity to humans of some pharmaceutical drugs: Alkylating agents, topoisomerase inhibitors or poisons, and DNA intercalators
Abstract The nonclinical branch of regulatory pharmacology has traditionally relied on the sensitivity and specificity of ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Towards therapeutic drug monitoring of mycophenolic acid in mucous membrane pemphigoid: A retrospective single‐centre study
Abstract Background Mycophenolate mofetil (MMF) is theoretically a treatment of choice for mucous membrane pemphigoid (MMP...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Induction of microtubule hyper stabilization and robust G2/M arrest by N‐4‐CN in human breast carcinoma MDA‐MB‐231 cells
Abstract Aim Elucidation of the antiproliferative efficacy and mechanism of action of a design-optimized noscapine analog,...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Variability of rituximab and tocilizumab trough concentrations in patients with rheumatoid arthritis
Abstract Patients with rheumatoid arthritis (RA) are eligible for treatment with therapeutic monoclonal antibodies (mAbs) ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Diarrhea and angiotensin II receptor blockers: Is there any difference between the different drugs?
Abstract Diarrhea is an adverse drug reaction (ADR) widely reported with olmesartan, an angiotensin II receptor blocker (A...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Recognition of potential therapeutic role of 2‐hydroxy‐3‐methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis
Abstract Background Gallbladder carcinoma (GBC), with early metastasis and high recurrence rates, is a enormous threat to ...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Antidepressants abuse in subjects with opioid use disorders: a 10‐year study in the French OPPIDUM program
Abstract Background Accumulating evidence shows that some antidepressants are abused for their psychostimulant effects, bu...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Relative Bioavailability and Pharmacokinetic Comparison of a Fixed‐Dose Combination Tablet of Mosapride, Pancreatin and Simethicone Relative to Single‐component Mosapride Tablets in Healthy Mexican Subjects
Abstract Abbott Laboratories de México S.A. de C.V. developed a new fixed dose combination of mosapride 5 mg, pancrea...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
Vortioxetine as an analgesic in preclinical inflammatory pain models: mechanism of action
Abstract Background Vortioxetine is a novel atypical antidepressant with multimodal activity that has recently demonstrate...
Fundamental & Clinical Pharmacology
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin