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The influence of PER3 VNTR genotypes on the age of onset in a group of bipolar I disorder patients: an exploratory study
The influence of PER3 VNTR genotypes on the age of onset in a group of bipolar I disorder patients: an exploratory study
PER3 is a circadian gene that contains a variable number of tandem repeats (VNTR) which codifies for three genotypes: 4/4;...
Integrated proteomic and genomic analysis to identify predictive biomarkers for valproate response in bipolar disorder: a 6-month follow-up study
Integrated proteomic and genomic analysis to identify predictive biomarkers for valproate response in bipolar disorder: a 6-month follow-up study
Several genetic studies have been undertaken to elucidate the intricate interplay between genetics and drug responses in b...
A systematic review of the biomarkers associated with cognition and mood state in bipolar disorder
A systematic review of the biomarkers associated with cognition and mood state in bipolar disorder
Bipolar disorder (BD) is a severe psychiatric disorder characterized by changes in mood that alternate between (hypo) mani...
Combining predominant polarity and affective spectrum concepts in bipolar disorder: towards a novel theoretical and clinical perspective
Combining predominant polarity and affective spectrum concepts in bipolar disorder: towards a novel theoretical and clinical perspective
This is an overview of recent advances on predominant polarity conceptualization in bipolar disorder (BD). Current evidenc...
Cluster analysis exploring the impact of childhood neglect on cognitive function in patients with bipolar disorder
Cluster analysis exploring the impact of childhood neglect on cognitive function in patients with bipolar disorder
Bipolar disorder (BD) is a severe mental disorder related to neurocognitive deficits. Exposure to childhood trauma is asso...
Why is lithium [not] the drug of choice for bipolar disorder? a controversy between science and clinical practice
Why is lithium [not] the drug of choice for bipolar disorder? a controversy between science and clinical practice
During over half a century, science has shown that lithium is the most efficacious treatment for bipolar...
Biomarkers for neurodegeneration impact cognitive function: a longitudinal 1-year case–control study of patients with bipolar disorder and healthy control individuals
Biomarkers for neurodegeneration impact cognitive function: a longitudinal 1-year case–control study of patients with bipolar disorder and healthy control individuals
Abnormalities in cerebrospinal fluid (CSF)-amyloid-beta (Aβ)42, CSF-Aβ40, CSF-Aβ38, CSF-soluble amyloid pre...
High lithium concentration at delivery is a potential risk factor for adverse outcomes in breastfed infants: a retrospective cohort study
High lithium concentration at delivery is a potential risk factor for adverse outcomes in breastfed infants: a retrospective cohort study
Neonatal effects of late intrauterine and early postpartum exposure to lithium through mother’s own milk are scarcel...
Behavioral lateralization in bipolar disorders: a systematic review
Behavioral lateralization in bipolar disorders: a systematic review
Bipolar disorder (BD) is often seen as a bridge between schizophrenia and depression in terms of symptomatology and etiolo...
Key questions on the long term renal effects of lithium: a review of pertinent data
Key questions on the long term renal effects of lithium: a review of pertinent data
For over half a century, it has been widely known that lithium is the most efficacious maintenance treatment for bipolar d...
Controversies regarding lithium-associated weight gain: case–control study of real-world drug safety data
Controversies regarding lithium-associated weight gain: case–control study of real-world drug safety data
The impact of long-term lithium treatment on weight gain has been a controversial topic with conflicting evidence. We aim ...
Supra-second interval timing in bipolar disorder: examining the role of disorder sub-type, mood, and medication status
Supra-second interval timing in bipolar disorder: examining the role of disorder sub-type, mood, and medication status
Widely reported by bipolar disorder (BD) patients, cognitive symptoms, including deficits in executive function, memory, a...
Association between childhood trauma, cognition, and psychosocial function in a large sample of partially or fully remitted patients with bipolar disorder and healthy participants
Association between childhood trauma, cognition, and psychosocial function in a large sample of partially or fully remitted patients with bipolar disorder and healthy participants
Childhood trauma (CT) are frequently reported by patients with bipolar disorder (BD), but it is unclear whether and how CT...
Countering the declining use of lithium therapy: a call to arms
Countering the declining use of lithium therapy: a call to arms
For over half a century, it has been widely known that lithium is the most efficacious treatment for bipolar disorder. Yet...
The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder
The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder
Intrusive mental imagery is associated with anxiety and mood instability within bipolar disorder and therefore represents ...
Mitochondrial genetic variants associated with bipolar disorder and Schizophrenia in a Japanese population
Mitochondrial genetic variants associated with bipolar disorder and Schizophrenia in a Japanese population
Bipolar disorder (BD) and schizophrenia (SZ) are complex psychotic disorders (PSY), with both environmental and genetic fa...
Rates and associations of relapse over 5 years of 2649 people with bipolar disorder: a retrospective UK cohort study
Rates and associations of relapse over 5 years of 2649 people with bipolar disorder: a retrospective UK cohort study
Evidence regarding the rate of relapse in people with bipolar disorder (BD), particularly from the UK, is lacking. This st...
Clinicians’ preferences and attitudes towards the use of lithium in the maintenance treatment of bipolar disorders around the world: a survey from the ISBD Lithium task force
Clinicians’ preferences and attitudes towards the use of lithium in the maintenance treatment of bipolar disorders around the world: a survey from the ISBD Lithium task force
Lithium has long been considered the gold-standard pharmacological treatment for the maintenance treatment of bipolar diso...
Phenotype fingerprinting of bipolar disorder prodrome
Phenotype fingerprinting of bipolar disorder prodrome
Detecting prodromal symptoms of bipolar disorder (BD) has garnered significant attention in recent research, as early inte...
Predictors of adherence to electronic self-monitoring in patients with bipolar disorder: a contactless study using Growth Mixture Models
Predictors of adherence to electronic self-monitoring in patients with bipolar disorder: a contactless study using Growth Mixture Models
Several studies have reported on the feasibility of electronic (e-)monitoring using computers or smartphones in patients w...
Racial differences in the major clinical symptom domains of bipolar disorder
Racial differences in the major clinical symptom domains of bipolar disorder
Across clinical settings, black individuals are disproportionately less likely to be diagnosed with bipolar disorder compa...
A compelling need to empirically validate bipolar depression
A compelling need to empirically validate bipolar depression
Allen J, Balfour R, Bell R, Marmot M. Social determinants of mental health. Int Rev Psychiatry. 2014;26(4):392–407.Article...
Methylomic biomarkers of lithium response in bipolar disorder: a clinical utility study
Methylomic biomarkers of lithium response in bipolar disorder: a clinical utility study
Response to lithium (Li) is highly variable in bipolar disorders (BD). Despite decades of research, no clinical predictor(...
Structured physical exercise for bipolar depression: an open-label, proof-of concept study
Structured physical exercise for bipolar depression: an open-label, proof-of concept study
Physical exercise (PE) is a recommended lifestyle intervention for different mental disorders and has shown specific posit...
Emotion regulation in bipolar disorder type-I: multivariate analysis of fMRI data
Emotion regulation in bipolar disorder type-I: multivariate analysis of fMRI data
Bipolar disorder type-I (BD-I) patients are known to show emotion regulation abnormalities. In a previous fMRI study using...
Stigma in people living with bipolar disorder and their families: a systematic review
Stigma in people living with bipolar disorder and their families: a systematic review
Stigma affects different life aspects in people living with bipolar disorder and their families. This study aimed to exami...
Lithium levels and lifestyle in patients with bipolar disorder: a new tool for self-management
Lithium levels and lifestyle in patients with bipolar disorder: a new tool for self-management
Patients should get actively involved in the management of their illness. The aim of this study was to assess the influenc...
Reduced parenting stress following a prevention program decreases internalizing and externalizing symptoms in the offspring of parents with bipolar disorder
Reduced parenting stress following a prevention program decreases internalizing and externalizing symptoms in the offspring of parents with bipolar disorder
Offspring of parents with bipolar disorder (OBD) are at risk for developing mental disorders, and the literature suggests ...
Lithium use in childhood and adolescence, peripartum, and old age: an umbrella review
Lithium use in childhood and adolescence, peripartum, and old age: an umbrella review
Lithium is one of the most consistently effective treatment for mood disorders. However, patients may show a high level of...
A systematic review on the effectiveness of dialectical behavior therapy for improving mood symptoms in bipolar disorders
A systematic review on the effectiveness of dialectical behavior therapy for improving mood symptoms in bipolar disorders
Evidence-based psychotherapies available to treat patients with bipolar disorders (BD) are limited. Dialectical behavior t...
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