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Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities
Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities
Patients with intellectual disabilities are shown to have a limited capacity for cooperation, communication,and other biol...
Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro
Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro
Inflammation plays a crucial role in the progression of Subacute Ruminal Acidosis (SARA). The experiment was designed to i...
D-galactose-induced mitochondrial oxidative damage and apoptosis in the cochlear stria vascularis of mice
D-galactose-induced mitochondrial oxidative damage and apoptosis in the cochlear stria vascularis of mice
Age-related hearing loss, known as presbycusis, is the result of auditory system degeneration. Numerous studies have sugge...
Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer
Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) regulates pre-mRNA processing and long non-coding RNA localization in t...
BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway
BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway
Bone morphogenetic protein 9 (BMP9) has been shown to regulate processes such as angiogenesis, endothelial dysfunction, an...
A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78
A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78
Cells can die through a process called apoptosis in both pathological and healthy conditions. Cancer development and progr...
Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance
Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance
Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action...
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress
Renal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI). Dysfunction of E74-like ETS transcr...
Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells
Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells
Janus kinase 3 (JAK3) is a member of the JAK family of tyrosine kinase proteins involved in cytokine receptor-mediated int...
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2
DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated dyslexia candidate genes in genetic studies. They both have demon...
Myogenic differentiation of human myoblasts and Mesenchymal stromal cells under GDF11 on Poly-ɛ-caprolactone-collagen I-Polyethylene-nanofibers
Myogenic differentiation of human myoblasts and Mesenchymal stromal cells under GDF11 on Poly-ɛ-caprolactone-collagen I-Polyethylene-nanofibers
For the purpose of skeletal muscle engineering, primary myoblasts (Mb) and adipogenic mesenchymal stem cells (ADSC) can be...
SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation
SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation
The platelet-derived growth factor (PDGF) family of ligands exerts their cellular effects by binding to α- and β...
Myogenic differentiation of human myoblasts and Mesenchymal stromal cells under GDF11 on NPoly-ɛ-caprolactone-collagen I-Polyethylene-nanofibers
Myogenic differentiation of human myoblasts and Mesenchymal stromal cells under GDF11 on NPoly-ɛ-caprolactone-collagen I-Polyethylene-nanofibers
For the purpose of skeletal muscle engineering, primary myoblasts (Mb) and adipogenic mesenchymal stem cells (ADSC) can be...
Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact
Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact
Cytochrome P450 4F2 (CYP4F2) enzyme is a member of the CYP4 family responsible for the metabolism of fatty acids, therapeu...
Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
Hypoxic culture conditions have been used to study the impact of oxygen deprivation has on gene expression in a number of ...
SCAT8/miR-125b-5p axis triggers malignant progression of nasopharyngeal carcinoma through SCARB1
SCAT8/miR-125b-5p axis triggers malignant progression of nasopharyngeal carcinoma through SCARB1
Nasopharyngeal carcinoma is a tumor with high malignancy and poor prognosis, which severely affects the health of the pati...
ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis
ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis
Recent studies have reported that the circadian transcription factor aryl hydrocarbon receptor nuclear translocator like 2...
Pre-treatment with IL-6 potentiates β-cell death induced by pro-inflammatory cytokines
Pre-treatment with IL-6 potentiates β-cell death induced by pro-inflammatory cytokines
Type I Diabetes mellitus (T1D) is characterized by a specific destruction of β-cells by the immune system. During thi...
Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions
Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions
Human accelerated regions (HARs) are short conserved genomic sequences that have acquired significantly more nucleotide su...
The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway
The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway
Endometriosis cause decreases in life quality and pelvic pain in reproductive-age women. Methylation abnormalities played ...
Role of the human solute carrier family 14 member 1 gene in hypoxia-induced renal cell carcinoma occurrence and its enlightenment to cancer nursing
Role of the human solute carrier family 14 member 1 gene in hypoxia-induced renal cell carcinoma occurrence and its enlightenment to cancer nursing
Hypoxia is considered a critical contributor to renal cell carcinoma progression, including invasion and metastasis. Howev...
Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3
Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3
Mechanical therapies, such as distraction osteogenesis, are widely used in dental clinics. During this process, the mechan...
Urine-derived mesenchymal stem cells-derived exosomes enhances survival and proliferation of aging retinal ganglion cells
Urine-derived mesenchymal stem cells-derived exosomes enhances survival and proliferation of aging retinal ganglion cells
This study was designed to investigate to test the effect of exosomes from urine-derived mesenchymal stem cells (USCs) on ...
Sperm capacitation and transcripts levels are altered by in vitro THC exposure
Sperm capacitation and transcripts levels are altered by in vitro THC exposure
Delta-9-tetrahydrocannabinol (THC) is the primary phytocannabinoid responsible for the psychoactive properties of cannabis...
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy
Abnormal biogenesis and ribosome free function of ribosomal proteins (RPs) is important for tumorgenesis and development. ...
The dual role of Nrf2 in melanoma: a systematic review
The dual role of Nrf2 in melanoma: a systematic review
Melanoma is the most lethal type of skin cancer that originates from the malignant transformation of melanocytes. Although...
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung
Bronchopulmonary dysplasia is a serious and lifelong pulmonary disease in premature neonates that influences around one-qu...
Circ-ATL1 silencing reverses the activation effects of SIRT5 on smooth muscle cellular proliferation, migration and contractility in intracranial aneurysm by adsorbing miR-455
Circ-ATL1 silencing reverses the activation effects of SIRT5 on smooth muscle cellular proliferation, migration and contractility in intracranial aneurysm by adsorbing miR-455
Alterations in vascular smooth muscle cells (VSMCs) contribute to the pathogenesis of intracranial aneurysms (IAs). Howeve...
HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis
HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis
Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying ...
N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling
N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling
Tendon injury is associated with oxidative stress, leading to reactive oxygen species (ROS) production and inflammation. N...
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