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Lncap-AI prostate cancer cell line establishment by Flutamide and androgen-free environment to promote cell adherent
Lncap-AI prostate cancer cell line establishment by Flutamide and androgen-free environment to promote cell adherent
To establish castration-resistant prostate cancer (CRPC) - Lncap androgen-independent (AI) cell line from Lncap androgen-d...
The role of the TGF-β/LIF signaling pathway mediated by SMADs during the cyst formation of Echinococcus in young children
The role of the TGF-β/LIF signaling pathway mediated by SMADs during the cyst formation of Echinococcus in young children
The present study aims to explore the correlation of the transforming growth factor β (TGF-β), drosophila mother...
CARD9 contributes to ovarian cancer cell proliferation, cycle arrest, and cisplatin sensitivity
CARD9 contributes to ovarian cancer cell proliferation, cycle arrest, and cisplatin sensitivity
Ovarian cancer recurrence and chemotherapy resistance are still urgent issues, and exploring the mechanisms of metastasis ...
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway
Abnormal expression of ribosomal proteins has an important regulatory effect on the progression of cancer. RPL5 is involve...
Downregulation of miR-451 in cholangiocarcinoma help the diagnsosi and promotes tumor progression
Downregulation of miR-451 in cholangiocarcinoma help the diagnsosi and promotes tumor progression
Cholangiocarcinoma is a kind of invasive malignant tumor followed by hepatocellular carcinoma. miR-451 was suggested to fu...
Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1β-treated chondrocyte cells
Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1β-treated chondrocyte cells
Acetaminophen is commonly recommended for the early analgesia of osteoarthritis. However, the molecular mechanism by which...
The role of proteoglycan form of DMP1 in cranial repair
The role of proteoglycan form of DMP1 in cranial repair
The cranial region is a complex set of blood vessels, cartilage, nerves and soft tissues. The reconstruction of cranial de...
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells
COVID-19 is a disease caused by SARS-CoV-2, which can cause mild to serious infections in humans. We aimed to explore the ...
Optimization of differentiation protocols of dental tissues stem cells to pancreatic β-cells
Optimization of differentiation protocols of dental tissues stem cells to pancreatic β-cells
Despite the recent progress in the differentiation strategies of stem cells into pancreatic beta cell lineage, current pro...
Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line
Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line
Aquaporins are channel proteins, form pores in the membrane of biological cells to facilitate the transcellular and transe...
In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor
In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor
The AAA + ATPase p97 is an essential unfoldase/segragase involved in a multitude of cellular processes. It fun...
Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics
Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics
Glioblastoma (GBM) represents nearly one-half of primary brain tumors, and the median survival of patients with GBM is onl...
Effects of an inhibitor of the SHH signaling pathway on endometrial cells of patients with endometriosis
Effects of an inhibitor of the SHH signaling pathway on endometrial cells of patients with endometriosis
Endometriosis is one of the most common gynecological diseases, and seriously reduces the quality of life of patients. How...
Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells
Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells
The non-catalytic region of tyrosine kinase (Nck) is an adaptor protein, which is ubiquitously expressed in many types of ...
Chromatin structure in cancer
Chromatin structure in cancer
In the past decade, we have seen the emergence of sequence-based methods to understand chromosome organization. With the c...
IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures
IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures
Intrinsically disordered proteins (IDPs) lack a stable three-dimensional structure under physiological conditions but play...
Systematic study of single-cell isolation from musculoskeletal tissues for single-sell sequencing
Systematic study of single-cell isolation from musculoskeletal tissues for single-sell sequencing
The single-cell platform provided revolutionary way to study cellular biology. Technologically, a sophistic protocol of is...
Induction of iPSC-derived Prg4-positive cells with characteristics of superficial zone chondrocytes and fibroblast-like synovial cells
Induction of iPSC-derived Prg4-positive cells with characteristics of superficial zone chondrocytes and fibroblast-like synovial cells
Lubricin, a proteoglycan encoded by the PRG4 gene, is synthesised by superficial zone (SFZ) chondrocytes and synovial cell...
MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma
MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma
In several human cancers, Krüppel-like factor 5 (KLF5), a zinc finger transcription factor, can contribute to both tu...
High D-glucose levels induce ACE2 expression via GLUT1 in human airway epithelial cell line Calu-3
High D-glucose levels induce ACE2 expression via GLUT1 in human airway epithelial cell line Calu-3
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the host cell by binding to angiotensin-converting enz...
Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress
Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress
Synechocystis histidine kinase, Sll0474: Hik28, a signal protein in a two-component signal transduction system, plays a cr...
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells
Poor decidualization and abnormal autophagy conditions in the endometria of adenomyosis patients have been reported previo...
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor
Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that promotes cell prolife...
OSGIN2 regulates osteogenesis of jawbone BMSCs in osteoporotic rats
OSGIN2 regulates osteogenesis of jawbone BMSCs in osteoporotic rats
Augmentation of oxidative stress after estrogen deficiency leading to functional deficiency of jawbone bone marrow mesench...