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Assessment of anticoagulant safety and coagulation analysis in mice using the VETSCAN® VSpro analyzer
Assessment of anticoagulant safety and coagulation analysis in mice using the VETSCAN® VSpro analyzer
Animal models of thrombosis play a critical role in research, helping us understand the mechanisms of hemostasis and throm...
Thrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery
Thrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery
Thrombin generation (TG) is reduced after cardiac surgery using cardiopulmonary bypass (CPB), contributing to coagulopathy...
Evaluation of unfractionated heparin therapy for venous thromboembolism using adjusted body weight in elderly or higher weight patients
Evaluation of unfractionated heparin therapy for venous thromboembolism using adjusted body weight in elderly or higher weight patients
The use of weight-based unfractionated heparin (UFH) infusions is the standard of care in hospital management of venous th...
Incidence and risk factors for venous thromboembolism in gynecological cancer: the GOTIC-VTE trial
Incidence and risk factors for venous thromboembolism in gynecological cancer: the GOTIC-VTE trial
Real-world data on venous thromboembolism (VTE) in Japanese patients with gynecological cancer are lacking. The GOTIC-VTE ...
Impact of antiplatelets, anticoagulants and cyclic nucleotide stimulators on neutrophil extracellular traps (NETs) and inflammatory markers during COVID-19
Impact of antiplatelets, anticoagulants and cyclic nucleotide stimulators on neutrophil extracellular traps (NETs) and inflammatory markers during COVID-19
While the association between coronavirus disease-19 (COVID-19) and neutrophils extracellular traps (NETs) is recognized, ...
The factor XI/XIa antibody abelacimab combined with enoxaparin inhibits filter clotting in hemodialysis circuits ex vivo
The factor XI/XIa antibody abelacimab combined with enoxaparin inhibits filter clotting in hemodialysis circuits ex vivo
Drugs targeting factor XI may offer an alternative to heparin for preventing blood clotting in extracorporeal circulation....
Real-world data on direct oral anticoagulants in BCR::ABL1-negative myeloproliferative neoplasms (MPNs): a multicenter retrospective study on behalf of scientific subcommittee on MPNs for Turkish society of hematology
Real-world data on direct oral anticoagulants in BCR::ABL1-negative myeloproliferative neoplasms (MPNs): a multicenter retrospective study on behalf of scientific subcommittee on MPNs for Turkish society of hematology
BCR::ABL1-negative myeloproliferative neoplasms (MPNs) pose a substantial risk of thrombosis, leading to significant morbi...
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Factor XIIa (FXIIa) is a plasma serine protease within the contact activation pathway. Inhibiting FXIIa could offer a viab...
3-Factor prothrombin complex concentrate versus 4-factor prothrombin complex concentrate for the reversal of oral factor Xa inhibitors
3-Factor prothrombin complex concentrate versus 4-factor prothrombin complex concentrate for the reversal of oral factor Xa inhibitors
Multiple agents exist for the reversal of oral Factor Xa inhibitor (FXa) associated bleeding, including Coagulation FXa Re...
Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study
Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study
Accurate risk stratification in acute intermediate-risk pulmonary embolism (PE) is essential. Current prediction scores la...
The protective effects of annexin A1 against oxidized-LDL-induced monocytes adhesion to endothelial cells: implication in atherosclerosis
The protective effects of annexin A1 against oxidized-LDL-induced monocytes adhesion to endothelial cells: implication in atherosclerosis
Oxidized low-density lipoprotein (ox-LDL)-associated endothelial dysfunction is a critical factor in the initiation and pr...
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity
• Hospitalized patients may exhibit discordance in aPTT and anti-Xa activities while on UFH. • In this study, ...
ASTRAL scale for predicting prognosis following intravenous thrombolysis with anterior versus posterior circulation acute ischemic stroke
ASTRAL scale for predicting prognosis following intravenous thrombolysis with anterior versus posterior circulation acute ischemic stroke
In this study, we compared whether there was any difference between the ASTRAL(Acute Stroke Registry and Analysis of Lausa...
Risk of venous thromboembolism after discontinuing prophylactic or therapeutic anticoagulation in patients with haematologic malignancies because of thrombocytopenia
Risk of venous thromboembolism after discontinuing prophylactic or therapeutic anticoagulation in patients with haematologic malignancies because of thrombocytopenia
Although the rates of thrombocytopenia in patients with hematologic malignancies are well known, clinical reports of patie...
Construction and validation of a nomogram prediction model for the catheter-related thrombosis risk of central venous access devices in patients with cancer: a prospective machine learning study
Construction and validation of a nomogram prediction model for the catheter-related thrombosis risk of central venous access devices in patients with cancer: a prospective machine learning study
Central venous access devices (CVADs) are integral to cancer treatment. However, catheter-related thrombosis (CRT) poses a...
Prediction of short-term adverse clinical outcomes of acute pulmonary embolism using conventional machine learning and deep Learning based on CTPA images
Prediction of short-term adverse clinical outcomes of acute pulmonary embolism using conventional machine learning and deep Learning based on CTPA images
To explore the predictive value of traditional machine learning (ML) and deep learning (DL) algorithms based on computed t...
Eosinopenia in patients with acute myocardial infarction- longitudinal imaging insights from the CAPRI study
Eosinopenia in patients with acute myocardial infarction- longitudinal imaging insights from the CAPRI study
Eosinophils are recruited to the heart during acute myocardial infarction (MI) and are considered part of the inflammatory...
A nomogram predicting venous thromboembolism risk in primary liver cancer patients
A nomogram predicting venous thromboembolism risk in primary liver cancer patients
Cancer frequently causes venous thromboembolism (VTE), a leading cause of cancer-related mortality. Primary liver cancer (...
Prognostic outcome of intravenous thrombolysis in elderly patients aged ≥ 60 years with acute ischemic stroke by ASTRAL and THRIVE scales
Prognostic outcome of intravenous thrombolysis in elderly patients aged ≥ 60 years with acute ischemic stroke by ASTRAL and THRIVE scales
This study aimed to validate the predictive performance of ASTRAL and THRIVE scales when used for patients aged 60 years a...
Risk of incident venous thromboembolism in patients with atopic dermatitis: systematic analysis of the literature and meta-analysis
Risk of incident venous thromboembolism in patients with atopic dermatitis: systematic analysis of the literature and meta-analysis
Previous studies have showed conflicting results regarding the association between atopic dermatitis (AD) and venous throm...
Interindividual variability in platelet reactivity among individuals with or without antiplatelet therapy: results from a large tertiary care hospital
Interindividual variability in platelet reactivity among individuals with or without antiplatelet therapy: results from a large tertiary care hospital
Antiplatelet therapy is crucial for reducing thrombotic events in patients with atherosclerotic disease, but the response ...
Heparin-like effect of a dual antiplatelet and anticoagulant (APAC) agent on red blood cell deformability and aggregation in an experimental model
Heparin-like effect of a dual antiplatelet and anticoagulant (APAC) agent on red blood cell deformability and aggregation in an experimental model
Treatments with different antithrombotic agents can affect micro-rheological variables, such as red blood cell (RBC) defor...
RNAi targeting LMAN1-MCFD2 complex promotes anticoagulation in mice
RNAi targeting LMAN1-MCFD2 complex promotes anticoagulation in mice
Combined deficiency of coagulation factor V (FV) and factor VIII (FVIII) is a rare bleeding disease caused by variants in ...
E-Cigarettes induce expression of procoagulant tissue factor in cultivated human endothelial cells
E-Cigarettes induce expression of procoagulant tissue factor in cultivated human endothelial cells
Background: E-cigarettes (ECIG) are proposed as an alternative for regular tobacco users with less dangerous effects for h...
Ghrelin may protect against vascular endothelial injury in Acute traumatic coagulopathy by mediating the RhoA/ROCK/MLC2 pathway
Ghrelin may protect against vascular endothelial injury in Acute traumatic coagulopathy by mediating the RhoA/ROCK/MLC2 pathway
Ghrelin exerts widespread effects in several diseases, but its role and mechanism in Acute Traumatic Coagulopathy (ATC) ar...
Mortality rate and factors associated with in-hospital mortality in patients hospitalized with pulmonary embolism in Germany
Mortality rate and factors associated with in-hospital mortality in patients hospitalized with pulmonary embolism in Germany
Pulmonary embolism (PE) is a life-threatening condition, the prognosis of which is determined in particular by acute decom...
Intravenous thrombolysis versus dual antiplatelet therapy in minor ischemic stroke within the thrombolytic window (TAMIS): a multicenter cohort study
Intravenous thrombolysis versus dual antiplatelet therapy in minor ischemic stroke within the thrombolytic window (TAMIS): a multicenter cohort study
Intravenous thrombolysis (IVT) and dual antiplatelet therapy (DAPT) have been widely used in minor ischemic stroke (MIS) t...
Finding individualised treatment in obese needing enoxaparin (FIT ONE): a multicentre study of therapeutic enoxaparin and the role of anti-factor Xa monitoring
Finding individualised treatment in obese needing enoxaparin (FIT ONE): a multicentre study of therapeutic enoxaparin and the role of anti-factor Xa monitoring
Enoxaparin is dosed according to actual body weight in treatment of arterial and venous thrombosis. Due to its hydrophilic...
The COVID-19 thrombus: distinguishing pathological, mechanistic, and phenotypic features and management
The COVID-19 thrombus: distinguishing pathological, mechanistic, and phenotypic features and management
A heightened risk for thrombosis is a hallmark of COVID-19. Expansive clinical experience and medical literature have char...
Effectiveness and safety of non-vitamin K antagonist oral anticoagulants in low-weight patients with atrial fibrillation
Effectiveness and safety of non-vitamin K antagonist oral anticoagulants in low-weight patients with atrial fibrillation
It remains unclear whether non-vitamin K antagonist oral anticoagulants (NOACs) are more effective and safer than warfarin...
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