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Overall haemostatic potential assay for prediction of outcomes in venous and arterial thrombosis and thrombo-inflammatory diseases
Overall haemostatic potential assay for prediction of outcomes in venous and arterial thrombosis and thrombo-inflammatory diseases
Thromboembolic diseases including arterial and venous thrombosis are common causes of morbidity and mortality globally. Th...
Layered plaque is associated with high levels of vascular inflammation and vulnerability in patients with stable angina pectoris
Layered plaque is associated with high levels of vascular inflammation and vulnerability in patients with stable angina pectoris
Layered plaque, a signature of previous plaque destabilization and healing, is a known predictor for rapid plaque progress...
Haemostatic gene variations in cervical cancer-associated venous thrombosis: considerations for clinical strategies
Haemostatic gene variations in cervical cancer-associated venous thrombosis: considerations for clinical strategies
Venous thromboembolism (VTE) is a life-threatening haemostatic disease frequently diagnosed among the cancer population. T...
Primary thromboprophylaxis in cancer outpatients – real-world evidence
Primary thromboprophylaxis in cancer outpatients – real-world evidence
Cancer-associated thrombosis (CAT) is a significant concern among patients with malignant diseases, leading to increased m...
Equivalent thrombotic risk with Warfarin, Dabigatran, or Enoxaparin after failure of initial direct oral anticoagulation (DOAC) therapy
Equivalent thrombotic risk with Warfarin, Dabigatran, or Enoxaparin after failure of initial direct oral anticoagulation (DOAC) therapy
The direct oral anticoagulants (DOACs) are now commonly regarded as first line anticoagulants in most cases of venous thro...
Impaired fibrinolysis in patients with atrial fibrillation and elevated circulating lipopolysaccharide
Impaired fibrinolysis in patients with atrial fibrillation and elevated circulating lipopolysaccharide
It is unknown whether elevated gut-derived serum lipopolysaccharide (LPS) can affect thrombin generation, fibrinolysis, an...
Comparison of the PADUA and IMPROVE scores in assessing venous thromboembolism risk in 42,257 medical inpatients in China
Comparison of the PADUA and IMPROVE scores in assessing venous thromboembolism risk in 42,257 medical inpatients in China
Venous thromboembolism (VTE) is a major contributor to hospital mortality and disability-adjusted life-year (DALY) loss. M...
Factor XI: structure, function and therapeutic inhibition
Factor XI: structure, function and therapeutic inhibition
Arterial and venous thromboembolism is a major medical concern that requires therapeutic anticoagulation in various medica...
Intravenous antiplatelet therapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
Intravenous antiplatelet therapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
The use of intravenous antiplatelet therapy during primary percutaneous coronary intervention (PPCI) is not fully standard...
Evaluation of modified fixed dose four-factor prothrombin complex concentrate for warfarin reversal
Evaluation of modified fixed dose four-factor prothrombin complex concentrate for warfarin reversal
Non-activated four-factor prothrombin complex concentrate (4 F-PCC) has emerged as the preferred reversal strateg...
Low-dose prasugrel versus standard-dose ticagrelor in east Asian patients with acute coronary syndrome
Low-dose prasugrel versus standard-dose ticagrelor in east Asian patients with acute coronary syndrome
Low-dose prasugrel demonstrated a similar effectiveness profile to clopidogrel in East Asian ACS patients, but its compari...
Impact of rise and fall phases of shear on platelet activation and aggregation using microfluidics
Impact of rise and fall phases of shear on platelet activation and aggregation using microfluidics
Blood flow disorders are often the result of the non-physiological narrowing of blood arteries caused by atherosclerosis a...
One-year morbidity and mortality in patients treated with standard-dose and low-dose apixaban after acute large vessel occlusion stroke
One-year morbidity and mortality in patients treated with standard-dose and low-dose apixaban after acute large vessel occlusion stroke
Although low-dose direct oral anticoagulants (DOACs) are recommended for patients at high risk of bleeding complications, ...
Management of direct oral anticoagulant drug interactions in hospitalized patients
Management of direct oral anticoagulant drug interactions in hospitalized patients
Moderate-strong CYP3A4 or Pgp inhibitors and inducers alter direct oral anticoagulant (DOAC) pharmacokinetics. Whether the...
Persistent hypofibrinolysis in severe COVID-19 associated with elevated fibrinolysis inhibitors activity
Persistent hypofibrinolysis in severe COVID-19 associated with elevated fibrinolysis inhibitors activity
Hypercoagulability and reduced fibrinolysis are well-established complications associated with COVID-19. However, the time...
COVID-19 vaccination affects short-term anti-coagulation levels in warfarin treatment
COVID-19 vaccination affects short-term anti-coagulation levels in warfarin treatment
Vaccines against SARS-CoV-2 have been recommended across the world, yet no study has investigated whether COVID-19 vaccina...
Benefit and risk of oral anticoagulant initiation strategies in patients with atrial fibrillation and cancer: a target trial emulation using the SEER-Medicare database
Benefit and risk of oral anticoagulant initiation strategies in patients with atrial fibrillation and cancer: a target trial emulation using the SEER-Medicare database
Oral anticoagulants (OACs) are recommended for patients with atrial fibrillation (AFib) having CHA2DS2-VASc score &#...
Prediction of mortality in acute pulmonary embolism in cancer-associated thrombosis (MAUPE-C): derivation and validation of a multivariable model
Prediction of mortality in acute pulmonary embolism in cancer-associated thrombosis (MAUPE-C): derivation and validation of a multivariable model
Optimal risk stratification of patients with cancer and pulmonary embolism (PE) remains unclear. We constructed a clinical...
Antithrombotic strategies for preventing graft failure in coronary artery bypass graft
Antithrombotic strategies for preventing graft failure in coronary artery bypass graft
Coronary artery bypass graft (CABG) procedures face challenges related to graft failure, driven by factors such as acute t...
Superficial vein thrombosis and its relationship with malignancies: a prospective observational study
Superficial vein thrombosis and its relationship with malignancies: a prospective observational study
The interrelation of cancer with venous thromboembolism is established, yet the specific impact on the incidence and progr...
Development of a routine bedside CYP2C19 genotype assessment program for antiplatelet therapy guidance in a community hospital catheterization laboratory
Development of a routine bedside CYP2C19 genotype assessment program for antiplatelet therapy guidance in a community hospital catheterization laboratory
Genotype based personalized antiplatelet therapy in the setting of percutaneous coronary intervention (PCI) has been studi...
Anticoagulation control among patients on vitamin K antagonists in nine countries in Sub-Saharan Africa
Anticoagulation control among patients on vitamin K antagonists in nine countries in Sub-Saharan Africa
Vitamin K antagonists (VKA) is the primary anticoagulant in most settings of Sub-Saharan Africa. Understanding the quality...
Discrimination of the acute pulmonary embolism subtypes based on the novel MAPH score
Discrimination of the acute pulmonary embolism subtypes based on the novel MAPH score
Acute pulmonary embolism (APE) is a thromboembolism situation that can be central or peripheral. APE risk analysis and cla...
Is a minimum duration of 5 days of unfractionated heparin infusion necessary before transition to oral anticoagulation in cerebral venous thrombosis? a retrospective chart review
Is a minimum duration of 5 days of unfractionated heparin infusion necessary before transition to oral anticoagulation in cerebral venous thrombosis? a retrospective chart review
In managing cerebral venous sinus thrombosis (CVT), the standard approach has been administering parenteral anticoagulatio...
The incidence of major bleeding in adult patients with urogenital and gynecological cancer being treated with direct oral anticoagulants (DOACs): a systematic review
The incidence of major bleeding in adult patients with urogenital and gynecological cancer being treated with direct oral anticoagulants (DOACs): a systematic review
Direct oral anticoagulants (DOACs) are the mainstay of treatment for venous thromboembolism (VTE) and non-valvular atrial ...
Retrospective, multicenter analysis of the safety and effectiveness of direct oral anticoagulants for the treatment of venous thromboembolism in obesity
Retrospective, multicenter analysis of the safety and effectiveness of direct oral anticoagulants for the treatment of venous thromboembolism in obesity
Direct oral anticoagulants (DOACs) are the preferred treatment for venous thromboembolism (VTE). However, DOAC use in pati...
Effect of continuous 2 MHz transcranial ultrasound as an adjunct to tenecteplase thrombolysis in acute anterior circulation ischemic stroke patients: an open labeled non-randomized clinical trial
Effect of continuous 2 MHz transcranial ultrasound as an adjunct to tenecteplase thrombolysis in acute anterior circulation ischemic stroke patients: an open labeled non-randomized clinical trial
The treatment of acute ischemic stroke has improved in last few decades. While meta-analyses of several trials have establ...
A systematic review of therapeutic enoxaparin dosing in obesity
A systematic review of therapeutic enoxaparin dosing in obesity
Enoxaparin is a hydrophilic drug with obesity having little effect on its apparent volume of distribution, therefore patie...
A ten-year comparison of treatment and outcomes of cancer-associated thrombosis to non-cancer venous thromboembolism: from traditional anticoagulants to direct oral anticoagulants
A ten-year comparison of treatment and outcomes of cancer-associated thrombosis to non-cancer venous thromboembolism: from traditional anticoagulants to direct oral anticoagulants
DOACs have emerged as first-line treatment in most cancer-associated thrombosis (CAT), representing a paradigm shift in it...
Impact of hemodialysis on efficacies of the antiplatelet agents in coronary artery disease patients complicated with end-stage renal disease
Impact of hemodialysis on efficacies of the antiplatelet agents in coronary artery disease patients complicated with end-stage renal disease
It is controversial whether hemodialysis affects the efficacy of the antiplatelet agents. We aimed to investigate the impa...
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