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Cerebrospinal fluid biomarkers and cognitive trajectories in patients with Alzheimer’s disease and a history of traumatic brain injury
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The relationship between cortical thickness and white matter hyperintensities in mid to late life
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Hypothalamic MRI-derived microstructure is associated with neurocognitive aging in humans
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Corticomuscular and intermuscular coherence as a function of age and walking balance difficulty
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Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer’s disease
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Cognitive reserve proxies are associated with age-related cognitive decline – not age-related gait speed decline
Cognitive reserve proxies are associated with age-related cognitive decline – not age-related gait speed decline
Cognitive reserve (CR) is a construct that can be used to account for individual differences in the relationship between b...
Hippocampal subfield volume in older adults with and without mild cognitive impairment: effects of worry and cognitive reappraisal
Hippocampal subfield volume in older adults with and without mild cognitive impairment: effects of worry and cognitive reappraisal
Anxiety disorders have the highest lifetime prevalence of any psychiatric disorder (Kessler et al., 2005), even in late-li...
Modulation of dorsal premotor cortex differentially influences visuomotor adaptation in young and older adults
Modulation of dorsal premotor cortex differentially influences visuomotor adaptation in young and older adults
The human neuromotor system is remarkably versatile and can quickly adapt complex visuomotor behaviour in response to the ...
Astrocytic-derived vascular remodeling factors are independently associated with blood brain barrier permeability in Alzheimer’s disease
Astrocytic-derived vascular remodeling factors are independently associated with blood brain barrier permeability in Alzheimer’s disease
Astrocytes in Alzheimer’s disease (AD) exert a pivotal role in the maintenance of blood-brain barrier (BBB) integrity esse...
Brain Reserve in Midlife is Associated with Executive Function Changes Across 12 Years
Brain Reserve in Midlife is Associated with Executive Function Changes Across 12 Years
Brain-predicted age difference scores (Brain-PADs) leverage machine learning to estimate the degree to which an individual...
Interstitial fluid flow decreases with age, especially after 50 years
Interstitial fluid flow decreases with age, especially after 50 years
Physiological age-related alterations in the interstitial flow in the brain, which plays an important role in waste produc...
Corrigendum to: “Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits” [Neurobiol. Aging 35 (2014) 1275–1285]
Corrigendum to: “Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits” [Neurobiol. Aging 35 (2014) 1275–1285]
Available online 22 May 2024Author links open overlay panelRui Liu a, Jin-ze Li a, Jun-ke Song a, Dan Zhou a, Chao Huang a...
Testing the Structural Disconnection Hypothesis: Myelin Content Correlates with Memory in Healthy Aging
Testing the Structural Disconnection Hypothesis: Myelin Content Correlates with Memory in Healthy Aging
Available online 23 May 2024Author links open overlay panel, , , , , , , , , , Highlights•Myelin in Prefrontal Areas Predi...
The associations among glycemic control, heart variability, and autonomic brain function in healthy individuals: Age- and sex-related differences
The associations among glycemic control, heart variability, and autonomic brain function in healthy individuals: Age- and sex-related differences
Glycemic control refers to the maintenance of blood glucose levels (Perlmuter et al., 2008) and is closely associated with...
Relationship between cortical brain atrophy, delirium, and long-term cognitive decline in older surgical patients
Relationship between cortical brain atrophy, delirium, and long-term cognitive decline in older surgical patients
Postoperative delirium is an acute confusional state that occurs in up to half of surgical patients aged 65 years or older...
Long-term calorie restriction reduces oxidative DNA damage to oligodendroglia and promotes homeostatic microglia in the aging monkey brain
Long-term calorie restriction reduces oxidative DNA damage to oligodendroglia and promotes homeostatic microglia in the aging monkey brain
Progressive cognitive decline is a hallmark of normal and degenerative brain aging and is characterized by deficits in lea...
Multiscale brain age prediction reveals region-specific accelerated brain aging in Parkinson's disease
Multiscale brain age prediction reveals region-specific accelerated brain aging in Parkinson's disease
Parkinson disease (PD) is the second most common neurodegenerative disease, with diverse etiological risk factors, includi...
Region-specific and age-related differences in astrocytes in the human brain
Region-specific and age-related differences in astrocytes in the human brain
KeywordsAstrocyte heterogeneityMass spectrometry-based proteomicsAgingHuman brainData availabilityThe proteomic dataset su...
Isoform-specific effects of neuronal inhibition of AMPK catalytic subunit on LTD impairments in a mouse model of Alzheimer’s disease
Isoform-specific effects of neuronal inhibition of AMPK catalytic subunit on LTD impairments in a mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is the most common cause of dementia syndrome in the elderly and a devastating neurodegenerative ...
Degree of multilingual engagement modulates resting state oscillatory activity across the lifespan
Degree of multilingual engagement modulates resting state oscillatory activity across the lifespan
Multilingualism has been demonstrated to lead to a more favorable trajectory of neurocognitive aging, yet our understandin...
Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium
Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium
AbbreviationsRPEretinal pigmented epitheliumAMDage-related macular degenerationTRAPTranslating Ribosome Affinity Purificat...
Slow wave activity disruptions and memory impairments in a mouse model of aging
Slow wave activity disruptions and memory impairments in a mouse model of aging
Volume 140, August 2024, Pages 12-21Author links open overlay panel, , , , , , , Highlights•Slow wave activity disruptions...
Reserve, resilience and maintenance of episodic memory and other cognitive functions in aging
Reserve, resilience and maintenance of episodic memory and other cognitive functions in aging
AbbreviationsAFQTArmed Forces Qualification TestAPOE-ɛ4apolipoprotein ɛ4CVLT-IICalifornia Verbal Learning Test–Second Edit...
High-fat diet and aging-associated memory impairments persist in the absence of microglia in female rats
High-fat diet and aging-associated memory impairments persist in the absence of microglia in female rats
Available online 1 May 2024Author links open overlay panel, , , , , , , , Highlights•Aging is associated with microglial p...
Age-related differences in functional connectivity associated with pain modulation
Age-related differences in functional connectivity associated with pain modulation
Growing evidence suggests that aging is associated with impaired endogenous pain modulation, and that this likely underlie...
Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer’s disease predicts cognitive decline
Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer’s disease predicts cognitive decline
Platelet activation of protease-activated receptor 4 (PAR4) and thrombin are at the top of a chain of events leading to fi...
The hippocampus as a structural and functional network epicentre for distant cortical thinning in neurocognitive aging
The hippocampus as a structural and functional network epicentre for distant cortical thinning in neurocognitive aging
Age-related neurocognitive disorders such as Alzheimer’s disease (AD) and mild cognitive impairment (MCI) involve widespre...
Free water-corrected fractional anisotropy of the fornix and parahippocampal cingulum predicts longitudinal memory change in cognitively healthy older adults
Free water-corrected fractional anisotropy of the fornix and parahippocampal cingulum predicts longitudinal memory change in cognitively healthy older adults
Compared to young adults, older adults consistently demonstrate reduced episodic memory performance, that is, poorer memor...
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with abnormalities in white matter structural integrity and connectivity: An ex-vivo diffusion MRI and pathology investigation
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with abnormalities in white matter structural integrity and connectivity: An ex-vivo diffusion MRI and pathology investigation
Mahir Tazwar: Writing – review & editing, Writing – original draft, Visualization, Validation, Software, Methodology, ...
Association of APOE genotype with blood-brain barrier permeability in neurodegenerative disorders
Association of APOE genotype with blood-brain barrier permeability in neurodegenerative disorders
The blood-brain barrier (BBB), a highly dynamic interface between the central nervous system and the peripheral circulatio...
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