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Shared decision-making and evidence-based medicine series: exploring contemporary challenges and future directions
Shared decision-making and evidence-based medicine series: exploring contemporary challenges and future directions
While there is consensus that shared decision-making should be an integral part of healthcare, there is ongoing debate abo...
Can a replication revolution resolve the duplication crisis in systematic reviews?
Can a replication revolution resolve the duplication crisis in systematic reviews?
The development of knowledge is for the most part a gradual and iterative process by which every new study either confirms...
Differences in shared decision-making: the East-West divide
Differences in shared decision-making: the East-West divide
Shared decision-making (SDM) integrates clinical evidence with patient preferences in established healthcare systems. More...
Meet generative AI... your new shared decision-making assistant
Meet generative AI... your new shared decision-making assistant
IntroductionLarge language models (LLMs), a new family of tools to generate natural language, are likely to radically chan...
Ambiguity in care delivery terminology: implications that affect pragmatic clinical trials using non-pharmacological interventions
Ambiguity in care delivery terminology: implications that affect pragmatic clinical trials using non-pharmacological interventions
Pragmatic clinical trials (PCTs) often study interventions delivered within the context of standard clinical encounters wi...
Feasibility of multiorgan risk prediction with routinely collected diagnostics: a prospective cohort study in the UK Biobank
Feasibility of multiorgan risk prediction with routinely collected diagnostics: a prospective cohort study in the UK Biobank
WHAT IS ALREADY KNOWN ON THIS TOPICPrimary care health checks (like the National Health Service Health Check) present a cr...
Clinician and health service interventions to reduce the greenhouse gas emissions generated by healthcare: a systematic review
Clinician and health service interventions to reduce the greenhouse gas emissions generated by healthcare: a systematic review
IntroductionThe delivery of modern healthcare is inadvertently exacerbating illness and injury to populations through its ...
Clinical trial design and treatment effects: a meta-analysis of randomised controlled and single-arm trials supporting 437 FDA approvals of cancer drugs and indications
Clinical trial design and treatment effects: a meta-analysis of randomised controlled and single-arm trials supporting 437 FDA approvals of cancer drugs and indications
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Vibration of effects resulting from treatment selection in mixed-treatment comparisons: a multiverse analysis on network meta-analyses of antidepressants in major depressive disorder
Vibration of effects resulting from treatment selection in mixed-treatment comparisons: a multiverse analysis on network meta-analyses of antidepressants in major depressive disorder
IntroductionNetwork meta-analyses (NMAs) are influential evidence synthesis tools often considered to dominate the hierarc...
Global considerations for informed consent with shared decision-making in the digital age
Global considerations for informed consent with shared decision-making in the digital age
Shared decision-making (SDM) is increasingly recognised as fundamental to patient-centred care and enabling patients to ma...
Development of the Reporting Infographics and Visual Abstracts of Comparative studies (RIVA-C) checklist and guide
Development of the Reporting Infographics and Visual Abstracts of Comparative studies (RIVA-C) checklist and guide
WHAT IS ALREADY KNOWN ON THIS TOPICMany health professionals, researchers and patients use infographics as a substitute fo...
Bad news: how the media reported on an observational study about cardiovascular outcomes of COVID-19
Bad news: how the media reported on an observational study about cardiovascular outcomes of COVID-19
Medical research gets plenty of media attention. Unfortunately, the attention is often problematic, frequently failing to ...
Call to improve transparent communication in direct-to-consumer test marketing
Call to improve transparent communication in direct-to-consumer test marketing
All tests ‘(…) do harm; some do good as well, and, of these, some do more good than harm at reasonable cost.’ Muir Gray an...
Reducing low value care: opportunities and challenges for Choosing Wisely campaigns
Reducing low value care: opportunities and challenges for Choosing Wisely campaigns
Low value care harms patients (due to adverse events of treatments or secondary unwarranted tests), overburdens healthcare...
Making sustainable healthcare decisions: three turns towards sustainable guidelines
Making sustainable healthcare decisions: three turns towards sustainable guidelines
Over time, an international consensus on ‘best practice’ for developing a range of guidelines has been reached in many are...
Open access journal publication in health and medical research and open science: benefits, challenges and limitations
Open access journal publication in health and medical research and open science: benefits, challenges and limitations
Scientific progress, including in evidence-based medicine, requires all available evidence to be accessed, scrutinised, in...
Adherence to the Guideline for Reporting Evidence-based practice Educational interventions and Teaching (GREET) of studies on evidence-based healthcare e-learning: a cross-sectional study
Adherence to the Guideline for Reporting Evidence-based practice Educational interventions and Teaching (GREET) of studies on evidence-based healthcare e-learning: a cross-sectional study
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies
Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies
WHAT IS ALREADY KNOWN ON THIS TOPICIt is well established that a shorter lifespan or premature death could be ascribed to ...
Trivalent and quadrivalent seasonal influenza vaccine in adults aged 60 and older: a systematic review and network meta-analysis
Trivalent and quadrivalent seasonal influenza vaccine in adults aged 60 and older: a systematic review and network meta-analysis
WHAT IS ALREADY KNOWN ON THIS TOPICSeasonal influenza vaccination of older adults (≥60 years old) is an important societal...
Rapid review methods series: Guidance on the use of supportive software
Rapid review methods series: Guidance on the use of supportive software
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThis paper presents an overview of considerations and recommendatio...
Preventing overdiagnosis and overuse: proposed guidance for guideline panels
Preventing overdiagnosis and overuse: proposed guidance for guideline panels
Moving from evidence to recommendations, guideline panels can influence decisions in everyday clinical practice. Consequen...
Survey of US physicians attitudes and knowledge of AI
Survey of US physicians attitudes and knowledge of AI
IntroductionArtificial intelligence (AI) applications in healthcare have proliferated over the past several years.1 Potent...
Teaching to address overdiagnosis
Teaching to address overdiagnosis
The whole art of medicine is in observation… but to educate the eye to see, the ear to hear and the finger to feel takes t...
Ethical implications of AI-driven bias assessment in medicine
Ethical implications of AI-driven bias assessment in medicine
Barsby et al present a thought-provoking pilot study which discusses the application of large language models (LLMs) for a...
Overly complex methods may impair pragmatic use of core evidence-based medicine principles
Overly complex methods may impair pragmatic use of core evidence-based medicine principles
The aphorism suggesting that we should keep things as simple as possible but not simpler applies well to the world of evid...
How methodological pitfalls have created widespread misunderstanding about long COVID
How methodological pitfalls have created widespread misunderstanding about long COVID
Key messagesThe existing epidemiological research on long COVID has suffered from overly broad case definitions and a stri...
High-value care education can learn from the evidence-based medicine movement: moving beyond competencies and curricula to culture
High-value care education can learn from the evidence-based medicine movement: moving beyond competencies and curricula to culture
High-value care (HVC) is ‘the best care for the patient, with the optimal result for the circumstances, delivered at the r...
Twenty-one years of the International Shared Decision Making Conference: lessons learnt and future priorities
Twenty-one years of the International Shared Decision Making Conference: lessons learnt and future priorities
The first International Shared Decision Making (ISDM) Conference took place in Oxford (UK), 2001. It was attended by 120 m...
Ecological study estimating melanoma overdiagnosis in the USA using the lifetime risk method
Ecological study estimating melanoma overdiagnosis in the USA using the lifetime risk method
WHAT IS ALREADY KNOWN ON THIS TOPICThe incidence of cutaneous melanoma has risen significantly in the USA over the past 40...
De-escalation of dual antiplatelet therapy for patients with acute coronary syndrome after percutaneous coronary intervention: a systematic review and network meta-analysis
De-escalation of dual antiplatelet therapy for patients with acute coronary syndrome after percutaneous coronary intervention: a systematic review and network meta-analysis
AbstractObjectives To compare dual antiplatelet therapy (DAPT) de-escalation with five alternative DAPT strategies in pati...
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