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Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference
Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference
Although ethanol administration produces a range of physiological effects, the rewarding aspect asso
The effect of early and long-term propranolol therapy on learning and memory in mice
The effect of early and long-term propranolol therapy on learning and memory in mice
Propranolol is the treatment of choice for infantile hemangioma. We investigated the effects of long
Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556
Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556
Cannabidiol is a phytocannabinoid that lacks the psychotomimetic properties of Δ9-tetrahydrocannabin
Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice
Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice
Autism spectrum disorder (ASD) describes a heterogeneous group of neurodevelopmental conditions char
Announcement of two Special Issues:‘Behavioural pharmacology of pain’ and ‘Sex differences in behavioural pharmacology’
Announcement of two Special Issues:‘Behavioural pharmacology of pain’ and ‘Sex differences in behavioural pharmacology’
Pain (Spring 2024) Pain is as diverse as it is ubiquitous. It is perhaps the health condition that most people ...
Long-term follow-up of intracerebroventricular injection of streptozotocin-inducing pain sensitization
Long-term follow-up of intracerebroventricular injection of streptozotocin-inducing pain sensitization
Age is known to be the major risk factor for both pain sensation and sporadic Alzheimer’s disease (s
Aldehyde dehydrogenase 2–associated changes in pharmacokinetics, locomotor function and peripheral glutamic acid and gamma-aminobutyric acid levels during acute alcohol intoxication in male mice
Aldehyde dehydrogenase 2–associated changes in pharmacokinetics, locomotor function and peripheral glutamic acid and gamma-aminobutyric acid levels during acute alcohol intoxication in male mice
The insufficiency of human aldehyde dehydrogenase 2 (ALDH2) has been consistently associated with hi
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats
Pain is a major problem that burdens the health and economy of societies worldwide. Nonsteroidal ant
Prenatal exposure to fluoxetine modulates emotionality and aversive memory in male and female rat offspring
Prenatal exposure to fluoxetine modulates emotionality and aversive memory in male and female rat offspring
During pregnancy, women are prone to depression, for which selective serotonin reuptake inhibitors (
Effort-based decision making in response to high-dose androgens: role of dopamine receptors
Effort-based decision making in response to high-dose androgens: role of dopamine receptors
Introduction Anabolic-androgenic steroids (AAS) are performance-enhancing drugs used by both worl
Involvement of GABAA receptors of lateral habenula in the acquisition and expression phases of morphine-induced place preference in male rats
Involvement of GABAA receptors of lateral habenula in the acquisition and expression phases of morphine-induced place preference in male rats
The lateral habenula (LHb) is a critical brain structure involved in the aversive response to drug a
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor
The effect of curcumin (Cur) on cognitive impairment and the possible role of brain tissue oxidative
Relapse to cotinine seeking in rats: differential effects of sex
Relapse to cotinine seeking in rats: differential effects of sex
Relapse is a defining feature of smoking and a significant challenge in cessation management. Elucid
The modulatory role of dopamine receptors within the hippocampal cornu ammonis area 1 in stress-induced analgesia in an animal model of persistent inflammatory pain
The modulatory role of dopamine receptors within the hippocampal cornu ammonis area 1 in stress-induced analgesia in an animal model of persistent inflammatory pain
The intrinsic pain inhibitory mechanisms can be activated by fear, anxiety, and stress. Stressful ex
Astaxanthin ameliorates serum level and spinal expression of macrophage migration inhibitory factor following spinal cord injury
Astaxanthin ameliorates serum level and spinal expression of macrophage migration inhibitory factor following spinal cord injury
Astaxanthin (AST) is a lipid-soluble carotenoid with antioxidant and anti-inflammatory properties. P
OREX-1038: a potential new treatment for pain with low abuse liability and limited adverse effects
OREX-1038: a potential new treatment for pain with low abuse liability and limited adverse effects
Drugs targeting mu opioid receptors are the mainstay of clinical practice for treating moderate-to-s
Preweaning environmental enrichment alters neonatal ultrasonic vocalisations in a rat model for prenatal infections
Preweaning environmental enrichment alters neonatal ultrasonic vocalisations in a rat model for prenatal infections
Objective Maternal infections are a well-known risk factor for neurodevelopmental defects. Such d
Punishment of ethanol choice in rhesus monkeys
Punishment of ethanol choice in rhesus monkeys
A defining characteristic of individuals diagnosed with alcohol use disorder (AUD) is that negative
Oxycodone decreases anxiety-like behavior in the elevated plus-maze test in male and female rats
Oxycodone decreases anxiety-like behavior in the elevated plus-maze test in male and female rats
The prescription opioid oxycodone is widely used for the treatment of pain in humans. Oxycodone misu
The discriminative stimulus effects of baclofen and gamma hydroxybutyrate in C57BL/6J mice
The discriminative stimulus effects of baclofen and gamma hydroxybutyrate in C57BL/6J mice
Baclofen and γ-hydroxybutyrate (GHB) exert γ-aminobutyric acid (GABA)B receptor agonism and have the
Cholinergic models of memory impairment in animals and man: scopolamine vs. biperiden
Cholinergic models of memory impairment in animals and man: scopolamine vs. biperiden
Scopolamine has been used as a pharmacologic model for cognitive impairments in dementia and Alzheim
Male and female rats exhibit comparable gaping behavior but activate brain regions differently during expression of conditioned nausea
Male and female rats exhibit comparable gaping behavior but activate brain regions differently during expression of conditioned nausea
Twenty-five to fifty percent of patients undergoing chemotherapy will develop anticipatory nausea an
Spontaneous alternation and stereotypical behaviour in deer mice: response to escitalopram and levetiracetam
Spontaneous alternation and stereotypical behaviour in deer mice: response to escitalopram and levetiracetam
Obsessive-compulsive disorder is varyingly associated with cognitive impairment, that is, deficits i
Editorial: The Behavioural Pharmacology of Cannabinoids
Editorial: The Behavioural Pharmacology of Cannabinoids
Humans have been using cannabis preparations for thousands of years for a variety of purposes. The scientific study of can...
Altered sleep during spontaneous cannabinoid withdrawal in male mice
Altered sleep during spontaneous cannabinoid withdrawal in male mice
Cessation of cannabinoid use in humans often leads to a withdrawal state that includes sleep disrupt
Blockade of the GABAB receptor suppressed alcohol self-administration in rats: an effect similar to that produced by GABAB receptor activation
Blockade of the GABAB receptor suppressed alcohol self-administration in rats: an effect similar to that produced by GABAB receptor activation
Literature data suggest that activation and blockade of the GABAB receptor may produce similar effec
The effects of subchronic agmatine on passive avoidance memory, anxiety-like behavior and hippocampal Akt/GSK-3β in mice
The effects of subchronic agmatine on passive avoidance memory, anxiety-like behavior and hippocampal Akt/GSK-3β in mice
Agmatine, a polyamine derived from l-arginine, has been suggested to modulate memory. However, the a
Effects of the psychoactive compounds in green tea on risky decision-making
Effects of the psychoactive compounds in green tea on risky decision-making
Epigallocatechin-3-gallate (EGCG) and caffeine are the two primary compounds found in green tea. Whi
Announcement of two special issues: behavioural pharmacology of synaptopathies and psychedelic drugs
Announcement of two special issues: behavioural pharmacology of synaptopathies and psychedelic drugs
Synaptopathies (Fall, 2022) Synaptic neurotransmission lies at the heart of nervous system's functioning. Clear...
Isobolographic analysis of antinociceptive effect of ketorolac, indomethacin, and paracetamol after simultaneous peripheral local and systemic administration
Isobolographic analysis of antinociceptive effect of ketorolac, indomethacin, and paracetamol after simultaneous peripheral local and systemic administration
This study was designed to characterize the type of interaction (subadditive, additive, or synergist
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