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Analysis of single-cell RNA sequencing in human oocytes with diminished ovarian reserve uncovers mitochondrial dysregulation and translation deficiency
Analysis of single-cell RNA sequencing in human oocytes with diminished ovarian reserve uncovers mitochondrial dysregulation and translation deficiency
Diminished ovarian reserve (DOR) is clinically characterized by a decrease in the number of available ovarian follicles an...
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
The female reproductive system can face serious disorders and show reproductive abnormalities under the influence of envir...
Identification of novel variants and candidate genes in women with 46,XX complete gonadal dysgenesis
Identification of novel variants and candidate genes in women with 46,XX complete gonadal dysgenesis
46,XX complete gonadal dysgenesis (46,XX-CGD) is a rare disorder of sexual development (DSD) characterized by primary amen...
Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro
Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro
Sperm capacitation is a prerequisite for natural or in vitro fertilization. After capacitation, sperm become hyperactivate...
Correlation between cardiometabolic index and female infertility: a cross-sectional analysis
Correlation between cardiometabolic index and female infertility: a cross-sectional analysis
Obesity and adverse lipid profile leads to female infertility. The cardiometabolic index (CMI) is a promising indicator fo...
Age-related testosterone decline: mechanisms and intervention strategies
Age-related testosterone decline: mechanisms and intervention strategies
Contemporary societies exhibit delayed reproductive age and increased life expectancy. While the male reproductive system ...
Melatonin supplementation attenuates cuproptosis and ferroptosis in aging cumulus and granulosa cells: potential for improving IVF outcomes in advanced maternal age
Melatonin supplementation attenuates cuproptosis and ferroptosis in aging cumulus and granulosa cells: potential for improving IVF outcomes in advanced maternal age
Advanced maternal age is associated with decreased oocyte quantity and quality and in vitro fertilization (IVF) success ra...
Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system
Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system
Mesenchymal stem cells (MSCs) have shown potential in repairing chemotherapy-induced premature ovarian failure (POF). Howe...
17α-Ethynylestradiol alters testicular epigenetic profiles and histone-to-protamine exchange in mice
17α-Ethynylestradiol alters testicular epigenetic profiles and histone-to-protamine exchange in mice
Spermatogenesis starts with the onset of puberty within the seminiferous epithelium of the testes. It is a complex process...
Non-invasively predicting euploidy in human blastocysts via quantitative 3D morphology measurement: a retrospective cohort study
Non-invasively predicting euploidy in human blastocysts via quantitative 3D morphology measurement: a retrospective cohort study
Blastocyst morphology has been demonstrated to be associated with ploidy status. Existing artificial intelligence models u...
MTHFR C677T、MTHFR A1298C、MTRR A66G and MTR A2756G polymorphisms and male infertility risk: a systematic review and meta-analysis
MTHFR C677T、MTHFR A1298C、MTRR A66G and MTR A2756G polymorphisms and male infertility risk: a systematic review and meta-analysis
Epidemiological studies have reported that polymorphisms of folate-metabolizing genes have a significant impact on male in...
Identify high-risk DOR women ≤ 35 years old following assisted reproduction technology through cutoffs of anti-mullerian hormone and antral follicle counts
Identify high-risk DOR women ≤ 35 years old following assisted reproduction technology through cutoffs of anti-mullerian hormone and antral follicle counts
Females with diminished ovarian reserve (DOR) have significantly lower cumulative live birth rates (CLBRs) than females wi...
Awareness and acceptability of assisted reproductive technology among non-medical tertiary students in a low-resource setting
Awareness and acceptability of assisted reproductive technology among non-medical tertiary students in a low-resource setting
Assisted Reproductive Techniques (ART) have significantly advanced infertility treatment worldwide. However their availabi...
A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT
A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT
At present, embryologists are attempting to use conventional in vitro fertilization (cIVF) as an alternative to intracytop...
Melatonin levels and embryo quality in IVF patients with diminished ovarian reserve: a comparative study
Melatonin levels and embryo quality in IVF patients with diminished ovarian reserve: a comparative study
Melatonin, a hormone found in various bodily fluids and cells, is known for its potent antioxidative, anti-apoptotic, and ...
Intraovarian injection of 3D-MSC-EVs-ECM gel significantly improved rat ovarian function after chemotherapy
Intraovarian injection of 3D-MSC-EVs-ECM gel significantly improved rat ovarian function after chemotherapy
Restoring the function of the ovary is important for chemotherapy-induced ovarian failure (COF) patients. Stem cell and ex...
The PPOS protocol mitigates the detrimental effects of high BMI on embryo and clinical pregnancy outcomes
The PPOS protocol mitigates the detrimental effects of high BMI on embryo and clinical pregnancy outcomes
The impact of high body mass index (BMI) on embryo and pregnancy outcomes in women using the PPOS (progestin-primed ovaria...
Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space
Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space
As interest in deep space travel grows exponentially, understanding human adaptation in becoming an interplanetary species...
GnRH agonist pretreatment for frozen embryo transfer among women with polycystic ovary syndrome: a narrow systematic review and meta-analysis of randomized controlled trials
GnRH agonist pretreatment for frozen embryo transfer among women with polycystic ovary syndrome: a narrow systematic review and meta-analysis of randomized controlled trials
Frozen embryo transfer (FET) is usually recommended for women with polycystic ovary syndrome (PCOS) undergoing In vitro fe...
Patients with low prognosis in ART: a Delphi consensus to identify potential clinical implications and measure the impact of POSEIDON criteria
Patients with low prognosis in ART: a Delphi consensus to identify potential clinical implications and measure the impact of POSEIDON criteria
Currently, there is no consensus on the optimal management of women with low prognosis in ART. In this Delphi consensus, a...
Identifying key predictive features for live birth rate in advanced maternal age patients undergoing single vitrified-warmed blastocyst transfer
Identifying key predictive features for live birth rate in advanced maternal age patients undergoing single vitrified-warmed blastocyst transfer
Infertility affects one in six couples worldwide, with advanced maternal age (AMA) posing unique challenges due to diminis...
Discussion on the evaluation of the therapeutic efficacy of uterine artery blood flow parameters and serum PLGF and sFlt-1 in patients with recurrent spontaneous abortion
Discussion on the evaluation of the therapeutic efficacy of uterine artery blood flow parameters and serum PLGF and sFlt-1 in patients with recurrent spontaneous abortion
To investigate the effects of different drug treatments on uterine artery blood flow parameters, serum placental growth fa...
Enhancing predictive models for egg donation: time to blastocyst hatching and machine learning insights
Enhancing predictive models for egg donation: time to blastocyst hatching and machine learning insights
Data sciences and artificial intelligence are becoming encouraging tools in assisted reproduction, favored by time-lapse t...
Effect of estradiol supplementation on luteal support following a significant reduction in serum estradiol levels after hCG triggering: a prospective randomized controlled trial
Effect of estradiol supplementation on luteal support following a significant reduction in serum estradiol levels after hCG triggering: a prospective randomized controlled trial
This study aimed to evaluate the impact of adding 4 mg estradiol valerate to progesterone for luteal support on p...
Asiaticoside ameliorates uterine injury induced by zearalenone in mice by reversing endometrial barrier disruption, oxidative stress and apoptosis
Asiaticoside ameliorates uterine injury induced by zearalenone in mice by reversing endometrial barrier disruption, oxidative stress and apoptosis
Zearalenone (ZEA) is a mycotoxin produced by Fusarium fungi that has been shown to have adverse effects on human and anima...
Correction: The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis
Correction: The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Vaginal and endometrial microbiome dysbiosis associated with adverse embryo transfer outcomes
Vaginal and endometrial microbiome dysbiosis associated with adverse embryo transfer outcomes
Assisted reproductive technology (ART) is the most effective method to treat infertility and the pathogenesis of implantat...
The role of ubiquitin-conjugating enzyme in the process of spermatogenesis
The role of ubiquitin-conjugating enzyme in the process of spermatogenesis
The ubiquitination is crucial for controlling cellular homeostasis and protein modification, in which ubiquitin-conjugatin...
Fance deficiency impaired DNA damage repair of prospermatogonia and altered the repair dynamics of spermatocytes
Fance deficiency impaired DNA damage repair of prospermatogonia and altered the repair dynamics of spermatocytes
Non-obstructive azoospermia (NOA) is the most severe form of male infertility and affects approximately 1% of men worldwid...
The prediction of semen quality based on lifestyle behaviours by the machine learning based models
The prediction of semen quality based on lifestyle behaviours by the machine learning based models
To find the machine learning (ML) method that has the highest accuracy in predicting the semen quality of men based on bas...
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