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Defining quality in thyroid FNA
Defining quality in thyroid FNA
Combining cytologic and molecular data may provide a useful approach to defining quality in thyroid fine-needle aspiration...
Combining molecular testing and the Bethesda category III:VI ratio for thyroid fine‐needle aspirates: A quality‐assurance metric for evaluating diagnostic performance in a cytopathology laboratory
Combining molecular testing and the Bethesda category III:VI ratio for thyroid fine‐needle aspirates: A quality‐assurance metric for evaluating diagnostic performance in a cytopathology laboratory
Background Molecular testing (MT) of thyroid fine-needle aspiration (FNA)-derived genetic material is commonly used to ass...
Effusion fluid cytology and COVID‐19 infection
Effusion fluid cytology and COVID‐19 infection
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease 2019...
Adequacy evaluation and use of pancreatic adenocarcinoma specimens for next‐generation sequencing acquired by endoscopic ultrasound–guided FNA and FNB
Adequacy evaluation and use of pancreatic adenocarcinoma specimens for next‐generation sequencing acquired by endoscopic ultrasound–guided FNA and FNB
Background Endoscopic ultrasound–guided tissue acquisition (EUS-TA), especially endoscopic ultrasound–guided...
Impact of bacillus Calmette‐Guerin intravesical therapy on the diagnostic efficacy of The Paris System for Reporting Urinary Cytology in patients with high‐grade bladder cancer
Impact of bacillus Calmette‐Guerin intravesical therapy on the diagnostic efficacy of The Paris System for Reporting Urinary Cytology in patients with high‐grade bladder cancer
Background In high-grade urothelial carcinoma (UC) of the bladder, bacillus Calmette-Guerin (BCG) therapy is a therapeutic...
Erratum to “Papillary lesions of the breast: A systematic evaluation of cytologic parameters”
Erratum to “Papillary lesions of the breast: A systematic evaluation of cytologic parameters”
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Risk stratification for cervical neoplasia using extended high‐risk HPV genotyping in women with ASC‐US cytology: A large retrospective study from China
Risk stratification for cervical neoplasia using extended high‐risk HPV genotyping in women with ASC‐US cytology: A large retrospective study from China
Background Extended high-risk human papillomavirus (hrHPV) genotype testing (hrHPVGT) has emerged as a new strategy to hel...
Utility of the Milan System for Reporting Salivary Gland Cytology, with focus on the incidence and histologic correlates of atypia of undetermined significance (AUS) and salivary gland neoplasm of uncertain malignant potential (SUMP): A 3‐year institutional experience
Utility of the Milan System for Reporting Salivary Gland Cytology, with focus on the incidence and histologic correlates of atypia of undetermined significance (AUS) and salivary gland neoplasm of uncertain malignant potential (SUMP): A 3‐year institutional experience
Background Fine-needle aspiration (FNA) is the preferred diagnostic test for salivary gland lesions. The purpose of the Mi...
Diversity, equity, and inclusion in pathology: A profound impact on patient care
Diversity, equity, and inclusion in pathology: A profound impact on patient care
Three years ago, Dina Greene, PhD, clinical associate professor of laboratory medicine and pathology at the University of ...
Thank You to Reviewers 2021
Thank You to Reviewers 2021
Cancer Cytopathology's reputation is determined by the quality of the manuscripts submitted and the expertise, dedication,...
Validation of the Milan System for Reporting Salivary Gland Cytopathology and the diagnostic accuracy of FNA cytology for submandibular gland lesions
Validation of the Milan System for Reporting Salivary Gland Cytopathology and the diagnostic accuracy of FNA cytology for submandibular gland lesions
Background The Milan System for Salivary Gland Cytopathology (MSRSGC) is a categorical system for salivary gland fine-need...
RAS mutation and associated risk of malignancy in the thyroid gland: An FNA study with cytology‐histology correlation
RAS mutation and associated risk of malignancy in the thyroid gland: An FNA study with cytology‐histology correlation
Background Activating point mutations of the RAS gene (NRAS, HRAS, and KRAS) can be seen in benign and malignant thyroid t...
Serial FNA allows direct sampling of malignant and infiltrating immune cells in patients with B‐cell lymphoma receiving immunotherapy
Serial FNA allows direct sampling of malignant and infiltrating immune cells in patients with B‐cell lymphoma receiving immunotherapy
BACKGROUND Fine-needle aspiration (FNA) is used to diagnose malignancies, recurrences, and metastases. The procedure is qu...
The utility of high‐risk human papillomavirus in situ hybridization in cytology cell block material from cystic head and neck lesions
The utility of high‐risk human papillomavirus in situ hybridization in cytology cell block material from cystic head and neck lesions
Background Human papillomavirus–related oropharyngeal squamous cell carcinoma (HPV-OPSCC) presents frequently as me...
Next‐generation sequencing in the evaluation of biliary strictures in patients with primary sclerosing cholangitis
Next‐generation sequencing in the evaluation of biliary strictures in patients with primary sclerosing cholangitis
BACKGROUND Primary sclerosing cholangitis (PSC) is a well-described risk factor for the development of cholangiocarcinoma ...
Diversity, equity, and inclusion in pathology: Some progress, but room for improvement
Diversity, equity, and inclusion in pathology: Some progress, but room for improvement
Volume 129, Issue 11 p. 837-838 CytoSource Amid a troubling backslide in diversifying medicine, pathologists...
A frameshift error affecting multiple cytology cell blocks: Lessons from a near‐miss event
A frameshift error affecting multiple cytology cell blocks: Lessons from a near‐miss event
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Evaluation and diagnostic value of next‐generation sequencing analysis of residual liquid‐based cytology specimens of pancreatic masses
Evaluation and diagnostic value of next‐generation sequencing analysis of residual liquid‐based cytology specimens of pancreatic masses
Background Liquid-based cytology (LBC) is a widely used method for processing specimens obtained by endoscopic biopsy. Thi...
Lymph node FNA cytology: Diagnostic performance and clinical implications of proposed diagnostic categories
Lymph node FNA cytology: Diagnostic performance and clinical implications of proposed diagnostic categories
Background Despite widespread clinical use, lymph node fine-needle aspiration cytology (LN-FNAC) lacks universal acceptanc...
NTRK‐rearranged papillary thyroid carcinoma demonstrates frequent subtle nuclear features and indeterminate cytologic diagnoses
NTRK‐rearranged papillary thyroid carcinoma demonstrates frequent subtle nuclear features and indeterminate cytologic diagnoses
Background The studies on the cytomorphologic features of NTRK-rearranged papillary thyroid carcinoma (PTC) are limited an...
Risk of malignancy associated with diagnostic categories of the proposed World Health Organization International System for reporting pancreatobiliary cytopathology
Risk of malignancy associated with diagnostic categories of the proposed World Health Organization International System for reporting pancreatobiliary cytopathology
In 2014, the Papanicolaou Society of Cytopathology (PSC) published terminology guidelines for reporting pancreatobiliary c...
Risk of malignancy associated with diagnostic categories of the proposed World Health Organization International System for Reporting Pancreaticobiliary Cytopathology
Risk of malignancy associated with diagnostic categories of the proposed World Health Organization International System for Reporting Pancreaticobiliary Cytopathology
Background The World Health Organization (WHO) has proposed an updated international classification system for reporting p...
Mitosis‐Karyorrhexis Index evaluation by digital image visual analysis for application of International Neuroblastoma Pathology Classification in FNA biopsy
Mitosis‐Karyorrhexis Index evaluation by digital image visual analysis for application of International Neuroblastoma Pathology Classification in FNA biopsy
Background The Mitosis-Karyorrhexis Index (MKI) score is important in neuroblastoma evaluation and in the application of t...
The American Thyroid Association (ATA) integrates molecular testing into its framework for managing patients with anaplastic thyroid carcinoma (ATC): Update on the 2021 ATA ATC guidelines
The American Thyroid Association (ATA) integrates molecular testing into its framework for managing patients with anaplastic thyroid carcinoma (ATC): Update on the 2021 ATA ATC guidelines
The recently published 2021 guidelines for the management of patients with anaplastic thyroid cancer from the American Thy...
Giant cell tumor of soft tissue: FNA cytopathology of 4 cases, review of the literature, and comparison with giant cell tumor of bone
Giant cell tumor of soft tissue: FNA cytopathology of 4 cases, review of the literature, and comparison with giant cell tumor of bone
Background The cytopathology of a giant cell tumor of soft tissue (GCT-ST), a fibrohistiocytic neoplasm distinct from othe...
Cytomorphologic features of intraductal salivary gland carcinoma: A multi‐institutional study of 13 FNA cases with histologic, molecular, and clinical correlations
Cytomorphologic features of intraductal salivary gland carcinoma: A multi‐institutional study of 13 FNA cases with histologic, molecular, and clinical correlations
Background Intraductal carcinoma of the salivary gland (IDC) is a rare cancer with potential actionable targets, including...
Tracking the twists and turns of a tumor's evolution
Tracking the twists and turns of a tumor's evolution
Volume 129, Issue 10 p. 757-758 CytoSource Concepts more familiar to evolutionary biologists and ecologists ...
IDK what's next for IDC: The unfolding saga of intraductal carcinoma of salivary glands
IDK what's next for IDC: The unfolding saga of intraductal carcinoma of salivary glands
In this issue of Cancer Cytopathology, Viswanathan et al further unravel the concept of intraductal carcinoma by detailing...
Cytomorphologic fatures of intraductal salivary gland carcinoma: A multi‐institutional study of 13 FNA cases with histologic, molecular, and clinical correlations
Cytomorphologic fatures of intraductal salivary gland carcinoma: A multi‐institutional study of 13 FNA cases with histologic, molecular, and clinical correlations
Background Intraductal carcinoma of the salivary gland (IDC) is a rare cancer with potential actionable targets, including...
Error rates in cytology clinical history are correlated with the number of “clicks“ needed to obtain it
Error rates in cytology clinical history are correlated with the number of “clicks“ needed to obtain it
Demanding more history from our clinical colleagues may be counterproductive because that provided history may be inaccura...
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