SCI时时刷

search
Risk of agranulocytosis with metamizole in comparison with alternative medications based on health records in Spain
Risk of agranulocytosis with metamizole in comparison with alternative medications based on health records in Spain
We aimed to estimate the absolute (incidence) and relative (hazard ratio; HR) risk of agranulocytosis associated with meta...
Synergizing pharmacometrics and pharmacovigilance for medication error management: the case of secukinumab
Synergizing pharmacometrics and pharmacovigilance for medication error management: the case of secukinumab
To demonstrate the effective integration of pharmacometrics and pharmacovigilance in managing medication errors, highlight...
Apixaban plasma concentrations in patients with obesity
Apixaban plasma concentrations in patients with obesity
Routine therapeutic drug monitoring of apixaban is currently not recommended but may however be warranted in some situatio...
Population pharmacokinetics and dosage optimization of linezolid in Chinese older patients
Population pharmacokinetics and dosage optimization of linezolid in Chinese older patients
To assess the pharmacokinetics and pharmacodynamics of linezolid in a retrospective cohort of hospitalized Chinese older p...
External validation of population pharmacokinetic models of tacrolimus in Thai adult liver transplant recipients
External validation of population pharmacokinetic models of tacrolimus in Thai adult liver transplant recipients
Several population pharmacokinetic models of tacrolimus in liver transplant patients were built, and their predictability ...
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers
Currently, body weight-based dosing of rifampicin is recommended. But lately, fat-free mass (FFM) was reported to be super...
Does the use of bisphosphonates during pregnancy affect fetal outcomes? A systematic review
Does the use of bisphosphonates during pregnancy affect fetal outcomes? A systematic review
This systematic review aimed to determine the effects of maternal exposure to bisphosphonates (BPs) during pregnancy on ne...
Effect of propranolol on pharmacokinetics of clozapine in schizophrenic patients: a meta-analysis
Effect of propranolol on pharmacokinetics of clozapine in schizophrenic patients: a meta-analysis
Clozapine is the effective therapy for treatment-refractory schizophrenia. However, the use of clozapine is limited by its...
Albumin: a comprehensive review and practical guideline for clinical use
Albumin: a comprehensive review and practical guideline for clinical use
Nowadays, it is largely accepted that albumin should not be used in hypoalbuminemia or for nutritional purpose. The most d...
Poor performance of ChatGPT in clinical rule-guided dose interventions in hospitalized patients with renal dysfunction
Poor performance of ChatGPT in clinical rule-guided dose interventions in hospitalized patients with renal dysfunction
Clinical decision support systems (CDSS) are used to identify drugs with potential need for dose modification in patients ...
“Always look at the outliers”: in memoriam Leif Bertilsson
“Always look at the outliers”: in memoriam Leif Bertilsson
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
High refill-adherence to adalimumab is associated with low disease activity in patients with inflammatory bowel disease
High refill-adherence to adalimumab is associated with low disease activity in patients with inflammatory bowel disease
Adalimumab has evolved to one of the more affordable first-line biologics for the treatment of inflammatory bowel disease ...