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Pain-Insomnia-Depression Syndrome: Triangular Relationships, Pathobiological Correlations, Current Treatment Modalities, and Future Direction
Pain-Insomnia-Depression Syndrome: Triangular Relationships, Pathobiological Correlations, Current Treatment Modalities, and Future Direction
Pain-insomnia-depression syndrome (PIDS) is a complex triad of chronic pain, insomnia, and depression that has profound ef...
Correlations of The Central Sensitization Inventory, conditioned pain modulation, cognitions and psychological factors in individuals with chronic neck pain: A cross-sectional study
Correlations of The Central Sensitization Inventory, conditioned pain modulation, cognitions and psychological factors in individuals with chronic neck pain: A cross-sectional study
Chronic neck pain (CNP) is a global public health problem, with high prevalence and absenteeism rates. Central sensitizati...
Efficacy and Adverse Effects of IV Morphine for Burn Pain Management in the Emergency Department: An Observational Study
Efficacy and Adverse Effects of IV Morphine for Burn Pain Management in the Emergency Department: An Observational Study
The management of pain following a burn is extremely complex because of the multifactorial nature of burn pain (nociceptiv...
Postoperative Dexmedetomidine Infusion and Chronic Postsurgical Pain in Thoracoscopic Pulmonary Nodule Surgery: A Retrospective Study with Propensity-Score-Matched Analysis
Postoperative Dexmedetomidine Infusion and Chronic Postsurgical Pain in Thoracoscopic Pulmonary Nodule Surgery: A Retrospective Study with Propensity-Score-Matched Analysis
Patients frequently suffer from debilitating chronic postsurgical pain (CPSP) subsequent to thoracoscopic surgery. The imp...
Durability of Evoked Compound Action Potential (ECAP)-Controlled, Closed-Loop Spinal Cord Stimulation (SCS) in a Real-World European Chronic Pain Population
Durability of Evoked Compound Action Potential (ECAP)-Controlled, Closed-Loop Spinal Cord Stimulation (SCS) in a Real-World European Chronic Pain Population
Closed-loop spinal cord stimulation (CL-SCS) is a recently introduced system that records evoked compound action potential...
A Novel Combination Strategy of Ultrasound-Guided Percutaneous Radiofrequency Ablation and Corticosteroid Injection for Treating Recalcitrant Plantar Fasciitis: A Retrospective Comparison Study
A Novel Combination Strategy of Ultrasound-Guided Percutaneous Radiofrequency Ablation and Corticosteroid Injection for Treating Recalcitrant Plantar Fasciitis: A Retrospective Comparison Study
The best treatment yielding clinical benefits was still equivocal and controversial for the treatment of recalcitrant plan...
Usefulness of Mirogabalin in Central Neuropathic Pain After Stroke: Post Hoc Analysis of a Phase 3 Study by Stroke Type and Location
Usefulness of Mirogabalin in Central Neuropathic Pain After Stroke: Post Hoc Analysis of a Phase 3 Study by Stroke Type and Location
Central post-stroke pain (CPSP) is a common type of central neuropathic pain (CNeP) that can occur following the onset of ...
Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy
Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy
Drawbacks of fixed-output spinal cord stimulation (SCS) screening trials may lead to compromised trial outcomes and poor p...
Potential Cost Savings with 60-day Peripheral Nerve Stimulation Treatment in Chronic Axial Low Back Pain
Potential Cost Savings with 60-day Peripheral Nerve Stimulation Treatment in Chronic Axial Low Back Pain
Chronic axial low back pain (CLBP) that is not responsive to medication management or physical therapy often requires sign...
Clinical Application of Different Doses of Hydromorphone Slow-Release Analgesia in Lumbar Fusion in Elderly Patients
Clinical Application of Different Doses of Hydromorphone Slow-Release Analgesia in Lumbar Fusion in Elderly Patients
The aim of this study is to examine the analgesic efficacy of varying doses of hydromorphone hydrochloride in conjunction ...
Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study
Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study
Up to 50% of diabetic patients with neuropathy suffer from chronic pain, namely painful diabetic neuropathy (PDN), an unme...
Dexketoprofen Trometamol and Tramadol Hydrochloride Fixed-Dose Combination in Moderate to Severe Acute Low Back Pain: A Phase IV, Randomized, Parallel Group, Placebo, Active-Controlled Study (DANTE)
Dexketoprofen Trometamol and Tramadol Hydrochloride Fixed-Dose Combination in Moderate to Severe Acute Low Back Pain: A Phase IV, Randomized, Parallel Group, Placebo, Active-Controlled Study (DANTE)
Dexketoprofen/tramadol 25/75 mg (DKP/TRAM) is a fixed-dose combination of a cyclooxygenase inhibitor and opioid receptor a...
Effect of Intravenous Sodium Pentobarbital on Pain and Sensory Abnormalities in Patients with Chronic Non-Cancer Pain: Narrative Literature Review, Research Study, and Illustrative Case Reports
Effect of Intravenous Sodium Pentobarbital on Pain and Sensory Abnormalities in Patients with Chronic Non-Cancer Pain: Narrative Literature Review, Research Study, and Illustrative Case Reports
Sodium pentobarbital (SP), a short- to intermediate-acting barbiturate, has limited information in the existing literature...
Innovative Applications of Telemedicine and Other Digital Health Solutions in Pain Management: A Literature Review
Innovative Applications of Telemedicine and Other Digital Health Solutions in Pain Management: A Literature Review
Since the COVID-19 pandemic, healthcare systems are facing extraordinary challenges. Our approaches to medicine have chang...
Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks
Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks
Around 91% of migraine patients use over-the-counter medicines to treat attacks, often without further treatment or medica...
Analgesic Effectiveness of Truncal Plane Blocks in Patients Undergoing the Nuss Procedure: A Randomized Controlled Trial
Analgesic Effectiveness of Truncal Plane Blocks in Patients Undergoing the Nuss Procedure: A Randomized Controlled Trial
Most patients undergoing the Nuss procedure reported moderate to severe pain after surgery. This study aimed to investigat...
Transcutaneous Electrical Acupoint Stimulation Combined with Moderate Sedation of Remimazolam Tosilate in Gastrointestinal Endoscopy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Transcutaneous Electrical Acupoint Stimulation Combined with Moderate Sedation of Remimazolam Tosilate in Gastrointestinal Endoscopy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Further clinical validation is required to determine whether transcutaneous electrical acupoint stimulation (TEAS) can rep...
Cortical Mechanisms Underlying Effects of Repetitive Peripheral Magnetic Stimulation on Dynamic and Static Postural Control in Patients with Chronic Non-Specific Low Back Pain: A Double-Blind Randomized Clinical Trial
Cortical Mechanisms Underlying Effects of Repetitive Peripheral Magnetic Stimulation on Dynamic and Static Postural Control in Patients with Chronic Non-Specific Low Back Pain: A Double-Blind Randomized Clinical Trial
Patients with chronic non-specific low back pain (CNLBP) often experience impaired postural control, contributing to pain ...
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled 14-Week Study of Mirogabalin in Chinese Patients with Diabetic Peripheral Neuropathic Pain
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled 14-Week Study of Mirogabalin in Chinese Patients with Diabetic Peripheral Neuropathic Pain
There is no approved effective drug for diabetic peripheral neuropathic pain (DPNP) in China. Gabapentinoids including mir...
The Use of High-Dose Intravenous l-Ascorbate in Pain Therapy: Current Evidence from the Literature
The Use of High-Dose Intravenous l-Ascorbate in Pain Therapy: Current Evidence from the Literature
Pain is the most common reason for seeking medical treatment. Despite extensive research efforts and effective analgesics ...
Development of a Prediction Model and Corresponding Scoring Table for Postherpetic Neuralgia Using Six Machine Learning Algorithms: A Retrospective Study
Development of a Prediction Model and Corresponding Scoring Table for Postherpetic Neuralgia Using Six Machine Learning Algorithms: A Retrospective Study
Postherpetic neuralgia (PHN), a complication of herpes zoster, significantly impacts the quality of life of affected patie...
Tension-Type Headache Management: A Systematic Review and Network Meta-analysis of Complementary and Alternative Medicine
Tension-Type Headache Management: A Systematic Review and Network Meta-analysis of Complementary and Alternative Medicine
Tension-type headache (TTH) is common but challenging to manage due to limited effectiveness of conventional treatments. T...
Percutaneous Foraminal Neuroplasty Using Reference Spinal Needles: Technical Description
Percutaneous Foraminal Neuroplasty Using Reference Spinal Needles: Technical Description
Lumbar foraminal stenosis is a common cause of chronic lower back pain and radiculopathy often treated by epidural steroid...
The Role of Astrocytes in Migraine with Cortical Spreading Depression: Protagonists or Bystanders? A Narrative Review
The Role of Astrocytes in Migraine with Cortical Spreading Depression: Protagonists or Bystanders? A Narrative Review
Cortical spreading depression (CSD) is a slow wave of cortical depolarization closely associated with migraines with an au...
Risk Factors Associated with Postoperative Cerebrospinal Fluid Leaks After Intrathecal Drug Delivery System and an External Pump Implantation in Cancer Patients: A Retrospective Study
Risk Factors Associated with Postoperative Cerebrospinal Fluid Leaks After Intrathecal Drug Delivery System and an External Pump Implantation in Cancer Patients: A Retrospective Study
To determine risk factors associated with postoperative cerebrospinal fluid leaks (CSFLs) after intrathecal drug delivery ...
Ketamine as Treatment for Cluster Headache: A Systematic Review of Literature and a Case Series
Ketamine as Treatment for Cluster Headache: A Systematic Review of Literature and a Case Series
Cluster headache is a severe and debilitating neurological condition characterized by intense, excruciating pain with a si...
H-Wave® Device Stimulation for Chronic Neck Pain: A Patient-Reported Outcome Measures (PROMs) Study
H-Wave® Device Stimulation for Chronic Neck Pain: A Patient-Reported Outcome Measures (PROMs) Study
Chronic neck pain (cNP) is one of the leading causes of disability worldwide, often being refractory to conventional forms...
A New Clinical Examination Algorithm to Prescribe Conservative Treatment in People with Hip-Related Pain
A New Clinical Examination Algorithm to Prescribe Conservative Treatment in People with Hip-Related Pain
Hip-related pain is a common issue in active adults affecting their quality of life, mobility, and overall function, and i...
Effectiveness of Vortioxetine in Patients with Major Depressive Disorder Associated with Chronic Pain: An Observational Study in a Spanish Population
Effectiveness of Vortioxetine in Patients with Major Depressive Disorder Associated with Chronic Pain: An Observational Study in a Spanish Population
Chronic pain (CP) and depression/anxiety often coexist, worsening each other's symptoms. Treating this comorbidity is ...
A Personalized Mediterranean Diet Improves Pain and Quality of Life in Patients with Fibromyalgia
A Personalized Mediterranean Diet Improves Pain and Quality of Life in Patients with Fibromyalgia
Fibromyalgia is a form of chronic pain that affects a large number of women. It can start at any age and last a lifetime, ...
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