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Carbon recycling with synthetic CO2 fixation pathways
Carbon recycling with synthetic CO2 fixation pathways
Carbon fixation lies in the heart of sustainability for alleviating global climate change and supporting lives on Earth. T...
Advances in enzymatic and organismal technologies for the recycling and upcycling of petroleum-derived plastic waste
Advances in enzymatic and organismal technologies for the recycling and upcycling of petroleum-derived plastic waste
The word ‘plastics’ is an umbrella term used for hundreds of unique materials. Colloquially, plastics often refer to a sma...
Advances in promoting chimeric antigen receptor T cell trafficking and infiltration of solid tumors
Advances in promoting chimeric antigen receptor T cell trafficking and infiltration of solid tumors
Chimeric antigen receptors (CARs) are synthetic receptors that can translate extracellular binding of tumor-associated ant...
Autophagy as a critical driver of metabolic adaptation, therapeutic resistance, and immune evasion of cancer
Autophagy as a critical driver of metabolic adaptation, therapeutic resistance, and immune evasion of cancer
Macroautophagy (hereafter autophagy) is a well-conserved catabolic process where intracellular components are targeted for...
Advances in generative modeling methods and datasets to design novel enzymes for renewable chemicals and fuels
Advances in generative modeling methods and datasets to design novel enzymes for renewable chemicals and fuels
Biotechnology has played a vital role in the development of alternative, sustainable energy sources over the past decade. ...
Emerging nonmodel eukaryotes for biofuel production
Emerging nonmodel eukaryotes for biofuel production
Global energy and environmental concerns have driven immense interest in developing biofuels as sustainable alternatives t...
Improving microbial bioproduction under low-oxygen conditions
Improving microbial bioproduction under low-oxygen conditions
Reducing the oxygen demand of a microbial bioconversion process would have a profound impact on lowering costs during scal...
Matching diverse feedstocks to conversion processes for the future bioeconomy
Matching diverse feedstocks to conversion processes for the future bioeconomy
A wide variety of wasted or underutilized organic feedstocks can be leveraged to build a sustainable bioeconomy, ranging f...
Design, construction, and application of noncanonical redox cofactor infrastructures
Design, construction, and application of noncanonical redox cofactor infrastructures
Controlling the flow of carbon and reducing power in biological systems is a central theme in metabolic engineering. Often...
Cell–nano interactions of polydopamine nanoparticles
Cell–nano interactions of polydopamine nanoparticles
Polydopamine (PDA) is an adhesive synthetic polymer coating derived from the oxidative polymerization of monomeric dopamin...
Proline metabolism shapes the tumor microenvironment: from collagen deposition to immune evasion
Proline metabolism shapes the tumor microenvironment: from collagen deposition to immune evasion
Proline is a nonessential amino acid, and its metabolism has been implicated in numerous malignancies. Together with a dir...
Modulation of immune cells with mRNA nanoformulations for cancer immunotherapy
Modulation of immune cells with mRNA nanoformulations for cancer immunotherapy
The rapid global development of safe and effective COVID-19 mRNA vaccines, greatly aided by nanotechnology, has sparked a ...
O-GlcNAcylation at the center of antitumor immunity
O-GlcNAcylation at the center of antitumor immunity
The post-translational modification known as O-GlcNAcylation is a highly dysregulated process in tumors, and a key contrib...
Nucleotide metabolism in the regulation of tumor microenvironment and immune cell function
Nucleotide metabolism in the regulation of tumor microenvironment and immune cell function
Nucleotide metabolism plays a crucial role in the regulation of the tumor microenvironment (TME) and immune cell function....
Interactions between nanoparticle corona proteins and the immune system
Interactions between nanoparticle corona proteins and the immune system
Nanomedicine has emerged as a versatile and important approach for drug delivery, imaging, and diagnosis. The unique physi...
Balancing safety and efficacy: tuning the biodistribution and pharmacokinetics of cytokine immunotherapies
Balancing safety and efficacy: tuning the biodistribution and pharmacokinetics of cytokine immunotherapies
The immune system plays a crucial role in the development and progression of many diseases, and immunotherapy provides an ...
The yin and yang of itaconate metabolism and its impact on the tumor microenvironment
The yin and yang of itaconate metabolism and its impact on the tumor microenvironment
The tumor microenvironment (TME) consists of diverse cell types and small molecules impacting tumorigenesis. The close int...
Editorial overview: Energy biotechnology as an integral solution to global challenges
Editorial overview: Energy biotechnology as an integral solution to global challenges
David Nielsen is a professor of chemical engineering at Arizona State University where, since 2015, he has also served as ...
Advances in genome-scale metabolic models of industrially important fungi
Advances in genome-scale metabolic models of industrially important fungi
Fungi possess exceptional metabolic versatility, robustness, and secretory capacity, which offer the potential to sustaina...
The aging tumor metabolic microenvironment
The aging tumor metabolic microenvironment
Approximately 70% of deaths from cancer occur in patients over 65 years old [1], and the rate of diagnosis is associated w...
Recent advances in systems metabolic engineering
Recent advances in systems metabolic engineering
The increasing concerns surrounding climate change and the reliance on petroleum-based industries have heightened the need...
Mining natural products for advanced biofuels and sustainable bioproducts
Mining natural products for advanced biofuels and sustainable bioproducts
The global production of fuels, chemicals, and plastics relies heavily on refined petroleum feedstocks. It is crucial to r...
Tumor lipid metabolism: a mechanistic link between diet and cancer progression
Tumor lipid metabolism: a mechanistic link between diet and cancer progression
The possibility of using ‘anti-cancer’ dietary interventions to prevent cancer onset or improve cancer prognosis is enthus...
Coupling chemistry and biology for the synthesis of advanced bioproducts
Coupling chemistry and biology for the synthesis of advanced bioproducts
Chemical and biological synthesis strategies have complementary strengths for exploiting new feedstocks and providing effi...
Capacitance sensors in cell-based bioprocesses: online monitoring of biomass and more
Capacitance sensors in cell-based bioprocesses: online monitoring of biomass and more
Biocapacitance measurement has emerged as a widely used technique for monitoring bioprocesses that involve living cells. O...
Strategies for uncovering stable isotope tracing patterns between cell populations
Strategies for uncovering stable isotope tracing patterns between cell populations
While metabolomics enables the relative quantification of a wide range of metabolites, one limitation is the capacity to g...
Editorial overview: Tissue, cell, and pathway engineering: Recent innovations in biomedical technologies
Editorial overview: Tissue, cell, and pathway engineering: Recent innovations in biomedical technologies
Dr. Jennifer Maynard is the ZD Bonner professor of chemical engineering. Her research focuses on the development of protei...
Sustainable metabolic engineering requires a perfect trifecta
Sustainable metabolic engineering requires a perfect trifecta
Over the past two centuries, humanity has relied primarily on fossil resources for power generation and chemical productio...
Editorial overview: 21st Century solutions for crop improvement
Editorial overview: 21st Century solutions for crop improvement
Alisdair Fernie is a group leader at the Max-Planck Institute or Molecular Plant Physiology as well as being a honorary pr...
Prospects of single-cell nuclear magnetic resonance spectroscopy with quantum sensors
Prospects of single-cell nuclear magnetic resonance spectroscopy with quantum sensors
Single-cell analysis can unravel functional heterogeneity within cell populations otherwise obscured by ensemble measureme...
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