×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Pharmacology & Pharmacy
30973
Global Medical University
4529
Allergy
1700
Anatomy & Morphology
1452
Andrology
414
Anesthesia & Intensive Care
1078
Anesthesiology
4975
Audiology & Speech-Language Pathology
311
Behavioral Sciences
100
Biochemical Research Methods
6146
Biochemistry & Molecular Biology
27233
Biodiversity Conservation
255
Biology
7464
Biophysics
7327
Biotechnology & Applied Microbiology
7463
Cardiac & Cardiovascular Systems
28686
Cardiovascular & Respiratory Systems
1293
Cell & Tissue Engineering
596
Cell Biology
10174
Chemistry, Analytical
3943
Chemistry, Applied
10436
Chemistry, Medicinal
8025
Chemistry, Multidisciplinary
17582
Clinical Immunology & Infectious Disease
397
Clinical Medicine
8391
Clinical Neurology
15073
Clinical Psychology & Psychiatry
1151
Critical Care Medicine
2840
Dentistry, Oral Surgery & Medicine
11841
Dermatology
7376
Developmental Biology
6540
Ecology
627
Education, Scientific Disciplines
1706
Emergency Medicine
3602
Endocrinology, Metabolism & Nutrition
21651
Engineering, Biomedical
3288
Entomology
392
Environmental Medicine & Public Health
4288
Evolutionary Biology
232
Gastroenterology & Hepatology
10831
General & Internal Medicine
6430
Genetics & Heredity
13597
Geriatrics & Gerontology
4637
Gerontology
314
Health Care Sciences & Services
14285
Health Policy & Services
542
Hematology
5108
Immunology
22980
Infectious Diseases
12671
Integrative & Complementary Medicine
2478
Medical Ethics
1028
Medical Informatics
1876
Medical Laboratory Technology
433
Medicine, General & Internal
41814
Medicine, Legal
426
Medicine, Research & Experimental
16140
Microbiology
21150
Mycology
0
Nanoscience & Nanotechnology
4607
Neuroimaging
1133
Neurology
4001
Neurosciences
35885
Nursing
8510
Nutrition & Dietetics
7462
Obstetrics & Gynecology
7478
Oncology
48343
Ophthalmology
8688
Optics
3623
Orthopedics
10330
Orthopedics, Rehabilitation & Sports Medicine
1576
Otolaryngology
1406
Otorhinolaryngology
4485
Parasitology
945
Pathology
4473
Pediatrics
19586
Peripheral Vascular Disease
4216
Pharmacology/Toxicology
11320
Physiology
8460
Polymer Science
496
Primary Health Care
737
Psychiatry
17335
Psychology
4644
Psychology, Applied
74
Psychology, Biological
295
Psychology, Clinical
710
Psychology, Developmental
204
Psychology, Educational
116
Psychology, Experimental
103
Psychology, Mathematical
0
Psychology, Multidisciplinary
1469
Psychology, Psychoanalysis
41
Psychology, Social
101
Public Health & Health Care Science
2073
Public, Environmental & Occupational Health
25429
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
11015
Radiology, Nuclear Medicine & Medical Imaging
7248
Rehabilitation
2795
Remote Sensing
0
Reproductive Biology
2513
Reproductive Medicine
1058
Research/Laboratory Medicine & Medical Technology
3584
Respiratory System
6468
Rheumatology
5243
Social Sciences, Biomedical
1109
Substance Abuse
2489
Surgery
30619
Toxicology
3979
Transplantation
878
Tropical Medicine
314
Urology & Nephrology
11732
Veterinary Sciences
35
Virology
2233
Zoology
0
渠道
CHEMICO-BIOLOGICAL INTERACTIONS
795
Medrxiv - Pharmacology and Therapeutics
159
AAPS JOURNAL
241
ACTA PHARMACOLOGICA SINICA
457
ADVANCED DRUG DELIVERY REVIEWS
0
ANTIVIRAL RESEARCH
0
CANCER CHEMOTHERAPY AND PHARMACOLOGY
309
CHEMMEDCHEM
274
CLINICAL PHARMACOKINETICS
287
CLINICAL PHARMACOLOGY & THERAPEUTICS
258
CNS DRUGS
168
CNS NEUROSCIENCE & THERAPEUTICS
116
DRUG DISCOVERY TODAY
185
DRUG METABOLISM AND DISPOSITION
324
DRUG RESISTANCE UPDATES
115
DRUG SAFETY
260
DRUGS
394
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
586
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
525
EUROPEAN JOURNAL OF PHARMACOLOGY
1277
INTERNATIONAL IMMUNOPHARMACOLOGY
2451
INTERNATIONAL JOURNAL OF PHARMACEUTICS
1752
JOURNAL OF CONTROLLED RELEASE
1152
JOURNAL OF ETHNOPHARMACOLOGY
2032
JOURNAL OF FOOD AND DRUG ANALYSIS
127
JOURNAL OF PHARMACEUTICAL ANALYSIS
319
NATURE REVIEWS DRUG DISCOVERY
534
NEUROPHARMACOLOGY
0
NEUROPSYCHOPHARMACOLOGY
645
NEUROTOXICOLOGY
0
PHARMACOGENOMICS
28
PHARMACOLOGY & THERAPEUTICS
303
PHARMACOTHERAPY
65
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
87
TOXICOLOGY AND APPLIED PHARMACOLOGY
1
TOXICOLOGY IN VITRO
366
VALUE IN HEALTH
20
VASCULAR PHARMACOLOGY
0
ANNALS OF PHARMACOTHERAPY
130
ANTIBIOTICS-BASEL
1984
BIOMEDICAL CHROMATOGRAPHY
243
BIOPHARMACEUTICS & DRUG DISPOSITION
20
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
0
CHEMOTHERAPY
81
CHINESE MEDICINE
365
CHIRALITY
73
CLINICAL NEUROPHARMACOLOGY
46
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT
129
CLINICAL THERAPEUTICS
52
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
55
DOSE-RESPONSE
78
DRUG DEVELOPMENT RESEARCH
121
EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE
230
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
617
HUMAN & EXPERIMENTAL TOXICOLOGY
105
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
0
INTERNATIONAL JOURNAL OF TOXICOLOGY
36
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
172
JOURNAL OF ANTIBIOTICS
220
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
349
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
30
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
170
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
1655
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
505
JOURNAL OF ONCOLOGY PHARMACY PRACTICE
176
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
0
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
0
JOURNAL OF PHARMACOLOGICAL SCIENCES
0
JOURNAL OF PHARMACY AND PHARMACOLOGY
18
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
464
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
121
PHARMACOGENOMICS & PERSONALIZED MEDICINE
249
PHARMACOLOGY
125
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
0
SKIN PHARMACOLOGY AND PHYSIOLOGY
70
THERAPEUTIC ADVANCES IN DRUG SAFETY
22
THERAPEUTIC DRUG MONITORING
172
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
10
INDIAN JOURNAL OF PHARMACOLOGY
16
JOURNAL OF APPLIED BIOMEDICINE
44
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
47
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
276
THERAPIE
289
SCIENTIA PHARMACEUTICA
108
ADMET AND DMPK
58
ADVANCED THERAPEUTICS
95
ADVANCES IN PHARMACOLOGY AND PHARMACY
76
ADVANCES IN TRADITIONAL MEDICINE
12
ASIAN JOURNAL OF PHARMACEUTICAL RESEARCH AND HEALTH CARE
26
ASIAN JOURNAL OF PHARMACEUTICS
160
CANADIAN JOURNAL OF HOSPITAL PHARMACY
143
CURRENT DRUG THERAPY
28
EGYPTIAN PHARMACEUTICAL JOURNAL
42
FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES
242
GABI JOURNAL-GENERICS AND BIOSIMILARS INITIATIVE JOURNAL
53
INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION
202
JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH
164
JOURNAL OF ANAESTHESIOLOGY CLINICAL PHARMACOLOGY
29
JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES
97
JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE
247
JOURNAL OF PHARMACOLOGY & PHARMACOTHERAPEUTICS
44
JOURNAL OF PHARMACY AND BIOALLIED SCIENCES
39
JOURNAL OF PHARMACY PRACTICE
98
JOURNAL OF RESEARCH IN PHARMACY PRACTICE
40
RESEARCH JOURNAL OF PHARMACOGNOSY
75
PHARMACEUTICAL MEDICINE
48
PHARMACIA
134
PHARMACOECONOMICS-OPEN
194
PHARMACY
176
PHARMACY PRACTICE-GRANADA
31
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
80
DRUGS & AGING
202
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
425
INVESTIGATIONAL NEW DRUGS
267
JOURNAL OF PHARMACEUTICAL INNOVATION
293
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
122
NEUROTHERAPEUTICS
335
PEDIATRIC DRUGS
148
THERAPEUTIC INNOVATION & REGULATORY SCIENCE
263
SCI时时刷
search
全部
推荐
+
Structural basis for inhibition of a GH116 β-glucosidase and its missense mutants by GBA2 inhibitors: Crystallographic and quantum chemical study
Human glucosylceramidase 2 (GBA2) is a nonlysosomal glucosylceramidase (E.C. 3.2.1.45), also known as bile acid β-glucosid...
Chemico-biological Interactions
comment
0
thumb_up
0
Ferroptosis contributes to cyclophosphamide-induced hemorrhagic cystitis
Cystitis is a common condition characterized by urinary bladder inflammation, which can significantly impact the quality o...
Chemico-biological Interactions
comment
0
thumb_up
0
Multi-omics profiling reveals cellular pathways and functions regulated by ALDH1B1 in colon cancer cells
By 2030, it is expected that the global burden of colon cancer will increase by 60%, with 2.2 million new cases and 1.1 mi...
Chemico-biological Interactions
comment
0
thumb_up
0
Rottlerin impairs early and late steps of Toxoplasma gondii infection in human trophoblast cells and villous explants
Toxoplasmosis, a serious food-borne illness mainly for congenitally-infected children and immunocompromised individuals, i...
Chemico-biological Interactions
comment
0
thumb_up
0
Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis
Matrine (MT) is an alkaloid found in the leguminous plant Sophora flavescens and has a long history of use in China and mo...
Chemico-biological Interactions
comment
0
thumb_up
0
A novel self-assembled nanoplatform based on retrofitting poloxamer 188 for triple-negative breast cancer targeting treatment
Breast cancer is a major global health concern and is the second leading cause of cancer related deaths among women worldw...
Chemico-biological Interactions
comment
0
thumb_up
0
Cu(II)-acylhydrazone complex, a potent and selective antitumor agent against human osteosarcoma: Mechanism of action studies over in vitro and in vivo models
Cancer is one of the main causes of death worldwide [1]. Particularly, osteosarcoma (OS) is a high-grade bone malignancy t...
Chemico-biological Interactions
comment
0
thumb_up
0
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes
As the physiological barrier of the body, intestinal homeostasis plays an important role in animal and human health [1]. E...
Chemico-biological Interactions
comment
0
thumb_up
0
Cardioprotective effect of the quercetin on cardiovascular remodeling and atherosclerosis in rodents fed a high-fat diet: A systematic review
According to the World Health Organization (WHO), chronic noncommunicable diseases currently represent 17.9 million of pre...
Chemico-biological Interactions
comment
0
thumb_up
0
Rosavin regulates bone homeostasis through HDAC1-induced epigenetic regulation of EEF2
Fractures resulting from osteoporosis (OP) become gradually prevalent in women aged over 55 years and men aged over 65 yea...
Chemico-biological Interactions
comment
0
thumb_up
0
Molecular targets and mechanisms of anti-cancer effects of withanolides
Cancer involves abnormal growth of cells with the potential to invade and metastasize to other parts of the body [1]. Nowa...
Chemico-biological Interactions
comment
0
thumb_up
0
Risk assessment of parabens in a transcriptomics-based in vitro test
Parahydroxybenzoates, often named ‘parabens’, are esters of 4-hydroxybenzoic acid and are effective antimicrobials and ant...
Chemico-biological Interactions
comment
0
thumb_up
0
Laxiflorin B covalently binds the tubulin colchicine-binding site to inhibit triple negative breast cancer proliferation and induce apoptosis
The global number of new breast cancer cases reported in 2020 reached ∼2.26 million, making it the most prevalent cancer i...
Chemico-biological Interactions
comment
0
thumb_up
0
Low levels of endogenous cholinesterases support the choice of cows, sheep and goats for the transgenic expression of human butyrylcholinesterase in milk
Human serum butyrylcholinesterase (Hu BChE) is a promising candidate enzyme for development as a prophylaxis for the prote...
Chemico-biological Interactions
comment
0
thumb_up
0
Particle-induced osteolysis is mediated by endoplasmic reticulum stress-associated osteoblast apoptosis
Aseptic loosening of artificial joints is a common complication of joint replacement, which is also the main reason for th...
Chemico-biological Interactions
comment
0
thumb_up
0
Metabolic characteristics of voriconazole – Induced liver injury in rats
Voriconazole (VOR) is a broad – spectrum antifungal agent, which is commonly used to treat invasive fungal infections caus...
Chemico-biological Interactions
comment
0
thumb_up
0
ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca2+ release sequentially triggering two different mechanisms of ROS formation
A 6 h exposure of U937 cells to 2.5 μM arsenite stimulates low Ca2+ release from the inositol 1, 4, 5-triphosphate recepto...
Chemico-biological Interactions
comment
0
thumb_up
0
Insights into the mechanisms of telbivudine-induced myopathy associated with mitochondrial dysfunction
Hepatitis B is a viral infection caused by the hepatitis B virus (HBV). It is a major public health concern, with an estim...
Chemico-biological Interactions
comment
0
thumb_up
0
Assessment of cellular damage with cytome assay among environmental/occupational triazole
In recent years, Brazil has become one of the main consumers of pesticides in the world, particularly in the agricultural ...
Chemico-biological Interactions
comment
0
thumb_up
0
Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers
Cancer is the leading cause of morbidity and mortality worldwide [1,2]. The hallmark characteristic of malignancies is the...
Chemico-biological Interactions
comment
0
thumb_up
0
Protective effects of phosphocreatine on human vascular endothelial cells against hydrogen peroxide-induced apoptosis and in the hyperlipidemic rat model
Atherosclerosis disease takes a significant toll on society and is induced by several factors, including inflammation, oxi...
Chemico-biological Interactions
comment
0
thumb_up
0
How do different bile acid derivatives affect rat macrophage function – Friends or foes?
Bile acids (BAs) are amphiphilic steroid molecules formed as end products of cholesterol metabolism. They are essential in...
Chemico-biological Interactions
comment
0
thumb_up
0
Astaxanthin ameliorates oxidative stress in lens epithelial cells by regulating GPX4 and ferroptosis
Age-related cataract (ARC) is a growing global public health problem that can lead to reduced vision and impaired visual f...
Chemico-biological Interactions
comment
0
thumb_up
0
Butyrylcholinesterase and lipid metabolism: Possible dual role in metabolic disorders
This study aims to compare three body mass index (BMI)-based classification systems of childhood obesity: the French, the ...
Chemico-biological Interactions
comment
0
thumb_up
0
Sequences, phylogeny and evolution of mitochondrial delta-1-pyrroline-5-carboxylate dehydrogenases (ALDH4A1). Evidence for a second locus (ALDH4A2) in Drosophila
Proline catabolism in the body involves two sequential enzyme reactions.Step 1: l-proline dehydrogenase [PRODH; EC 1.5.5.2...
Chemico-biological Interactions
comment
0
thumb_up
0
TUG1 protects against ferroptosis of hepatic stellate cells by upregulating PDK4-mediated glycolysis
Liver fibrosis, an ongoing wound-healing process, results in the aberrant accumulation of extracellular matrix proteins an...
Chemico-biological Interactions
comment
0
thumb_up
0
Gypenosides suppress hepatocellular carcinoma cells by blocking cholesterol biosynthesis through inhibition of MVA pathway enzyme HMGCS1
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and represents a major global healthcare challe...
Chemico-biological Interactions
comment
0
thumb_up
0
Discovery of acylated isoquercitrin derivatives as potent anti-neuroinflammatory agents in vitro and in vivo
Neuroinflammation refers to an inflammatory response within the central nervous system (CNS) that is induced by activated ...
Chemico-biological Interactions
comment
0
thumb_up
0
The ESTHER database on alpha/beta hydrolase fold proteins - An overview of recent developments
Neuroinflammation is considered as an important pathological mechanism in neurodegenerative diseases. The natural isoquerc...
Chemico-biological Interactions
comment
0
thumb_up
0
Solvents and detergents compatible with enzyme kinetic studies of cholinesterases
Cholinesterases are serine hydrolase enzymes that are integral to a variety of physiological functions [1]. Acetylcholines...
Chemico-biological Interactions
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin