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Retraction Note: circ_001504 promotes the development of renal cell carcinoma by sponging microRNA-149 to increase NUCB2
Authors and AffiliationsJilin University, 130000, Changchun, P. R. ChinaRui Xin, Danhua Qu, Huiying Xu & Dawei ChenDep...
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer
WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer
The tumor suppressor gene WWOX is localized in an unstable chromosomal region and its expression is decreased or absent in...
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis
c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis
Elevated expression of c-Myc is associated with a variety of human cancers including clear cell renal cell carcinoma (ccRC...
P38 kinase in gastrointestinal cancers
P38 kinase in gastrointestinal cancers
Gastrointestinal cancers are a leading cause of cancer morbidity and mortality worldwide with 4.2 million new cases and 3....
Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention
Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention
Head and neck squamous cell carcinoma (HNSCC) is a significant public health problem, with a need for novel approaches to ...
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate
Extracellular vesicles released by glioma cells are decorated by Annexin A2 allowing for cellular uptake via heparan sulfate
Extracellular vesicles (EVs) play a crucial role in regulating cell behavior by delivering their cargo to target cells. Ho...
Role of non-coding RNAs in neuroblastoma
Role of non-coding RNAs in neuroblastoma
Neuroblastoma is known as the most prevalent extracranial malignancy in childhood with a neural crest origin. It has been ...
RNA N6-methyladenosine (m6A) modification in HNSCC: molecular mechanism and therapeutic potential
RNA N6-methyladenosine (m6A) modification in HNSCC: molecular mechanism and therapeutic potential
Head and neck squamous cell carcinoma ranks seventh in incidence of malignant tumours in the world. Although there are tre...
TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4
TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4
Ovarian cancer is the most lethal gynecological malignancy and is characterized by peritoneal disseminated metastasis. Alt...
FIT links c-Myc and P53 acetylation by recruiting RBBP7 during colorectal carcinogenesis
FIT links c-Myc and P53 acetylation by recruiting RBBP7 during colorectal carcinogenesis
Colorectal cancer (CRC) poses one of the most serious threats to human health worldwide, and abnormally expressed c-Myc an...
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis
Despite their rarity, PIK3CA mutations in meningiomas have raised interest as potentially targetable, ubiquitous mutations...
Self-replicating messenger RNA based cancer immunotherapy
In 1989, the Nobel Prize in chemistry was awarded to Thomas Cech for his findings that RNA in living cell...
Correction to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP2
METTL3 promotes the malignancy of non-small cell lung cancer by N6-methyladenosine modifying SFRP2
This study aimed to investigate the roles of METTL3, a regulator of m6A, in NSCLC. RT-qPCR was applied to determine mRNA o...
Recent progress in exosome research: isolation, characterization and clinical applications
Recent progress in exosome research: isolation, characterization and clinical applications
Exosomes, a kind of nano-vesicles released by various cell types, carry a variety of “cargos” including protei...
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment
Estrogen receptor status heterogeneity in breast cancer tumor: role in response to endocrine treatment
Tumor heterogeneity affects diagnosis, prognosis and response to therapy. Heterogeneity is found in both normal and neopla...
Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
Lycium barbarum polysaccharide (LBP) is a substance with various biological activities extracted from Lycium barbarum. LbG...
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas
Members of the HDAC family are predictive biomarkers and regulate the tumorigenesis in several cancers. However, the role ...
PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression
PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression
Proteasome 26S subunit, non-ATPase 12 (PSMD12) genes have been implicated in several types of malignancies but the role of...
Ewing sarcoma treatment: a gene therapy approach
Ewing sarcoma (ES) is an aggressive malignant tumor, characterized by non-random chromosomal translocations that produce f...
Retraction Note: CREB3L4 promotes angiogenesis and tumor progression in gastric cancer through regulating VEGFA expression
Authors and AffiliationsDepartment of Digestive Internal Medicine, Gaozhou People’s Hospital, Gaozhou City, Guangdong Prov...
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance
Despite the development of new classes of targeted anti-cancer drugs, the curative treatment of metastatic solid tumors re...
Reductive cell death: the other side of the coin
Reductive cell death: the other side of the coin
The balance between oxidants and antioxidants within cells, known as redox homeostasis, is crucial for proper cellular fun...
Improving poxvirus-mediated antitumor immune responses by deleting viral cGAMP-specific nuclease
Improving poxvirus-mediated antitumor immune responses by deleting viral cGAMP-specific nuclease
cGAMP-specific nucleases (poxins) are a recently described family of proteins dedicated to obstructing cyclic GMP-AMP synt...
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression
Immuno-regulatory malignant B cells contribute to Chronic Lymphocytic Leukemia progression
Chronic Lymphocytic Leukemia (CLL) is a heterogeneous B cell neoplasm ranging from indolent to rapidly progressive disease...
E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA
E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA
Hepatocellular carcinoma (HCC) is a gastrointestinal tumor with high clinical incidence. Long non-coding RNAs (lncRNAs) pl...
CAFrgDB: a database for cancer-associated fibroblasts related genes and their functions in cancer
CAFrgDB: a database for cancer-associated fibroblasts related genes and their functions in cancer
As one of the most essential components of the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) interact...
MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo
MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo
MORC family CW-type zinc finger 4 (MORC4) possessing nuclear matrix binding domains has been observed to be involved in mu...
Loss of EPS8 sensitizes non-small-cell lung carcinoma to chemotherapy-induced DNA damage
Loss of EPS8 sensitizes non-small-cell lung carcinoma to chemotherapy-induced DNA damage
Epidermal growth factor receptor pathway substrate number 8 (EPS8) has been reported to be critical in mediating tumor pro...
Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway
Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway
The tumor-elicited inflammation is closely related to tumor microenvironment during tumor progression. S100A8, an endogeno...
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