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„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
Dieser Aufsatz zeigt anhand der Hamburger Anthropologie des 20. Jahrhunderts, wie historisch spezifische Aufschre...
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in several studies with conflicting res...
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular testing in breast cancer gained increasing attention and importance as specific molecular results can tailor not...
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Human epidermal growth factor receptor 2 (HER)-positive breast cancer (BC) is characterized by an aggressive clinical cour...
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
Cancer of unknown primary (CUP) presents a complex diagnostic challenge, characterized by metastatic tumors of unknown tis...
Genomic alterations and diagnosis of renal cancer
Genomic alterations and diagnosis of renal cancer
The application of molecular profiling has made substantial impact on the classification of urogenital tumors. Therefore, ...
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
A liver biopsy is essential for the diagnostic workup of persistent neonatal cholestasis (NC). The differential diagnosis ...
Molecular pathology as basis for timely cancer diagnosis and therapy
Molecular pathology as basis for timely cancer diagnosis and therapy
Precision and personalized therapeutics have witnessed significant advancements in technology, revolutionizing the capabil...
T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature
T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature
In the 2022, WHO and ICC classifications, myeloid/lymphoid neoplasms with eosinophilia (M/LN-eo) and tyrosine kinase gene ...
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Medical oncology is rapidly evolving with the implementation of personalized, targeted therapies. Advances in molecular di...
Adenoid cystic carcinoma metastatic to the kidney: a series of 10 patients emphasizing unilateral presentation and long time interval from primary diagnosis
Adenoid cystic carcinoma metastatic to the kidney: a series of 10 patients emphasizing unilateral presentation and long time interval from primary diagnosis
Adenoid cystic carcinoma (AdCC) metastasis to kidney is rare. We identified 10 patients with metastatic AdCC in multi-inst...
Clinicopathological differences in focal segmental glomerulosclerosis depending on the accompanying pathophysiological conditions in renal allografts
Clinicopathological differences in focal segmental glomerulosclerosis depending on the accompanying pathophysiological conditions in renal allografts
Primary focal segmental glomerulosclerosis (FSGS) is thought to be caused by circulating factors leading to podocytopathy,...
Correction to: Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Correction to: Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Pathology Unit, Department of Molecular and Translational Medicine-DMMT, University of Brescia, Brescia, ItalyLuisa Lorenz...
The HER2-low revolution in gynecological oncology: could it be a realistic emerging challenge?
The HER2-low revolution in gynecological oncology: could it be a realistic emerging challenge?
Ovarian clear cell carcinoma (OCCC) is a high-grade adenocarcinoma, often endometriosis related, generally diagnosed in yo...
Correction to: Voices from the past: results of the ESP history of pathology working group survey on pathology museums
Correction to: Voices from the past: results of the ESP history of pathology working group survey on pathology museums
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Bericht der Arbeitsgemeinschaft Geschichte und Ethik der Pathologie der Deutschen Gesellschaft für Pathologie
Bericht der Arbeitsgemeinschaft Geschichte und Ethik der Pathologie der Deutschen Gesellschaft für Pathologie
Interessenkonflikt T. Braunschweig und K. Schierle geben an, dass k...
Erythrophagocytosis is not a reproducible finding in liver biopsies, and is not associated with clinical diagnosis of hemophagocytic lymphohistiocytosis
Erythrophagocytosis is not a reproducible finding in liver biopsies, and is not associated with clinical diagnosis of hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a rare disease with high mortality. Liver involvement is common (based on elev...
STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons
STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons
Granulomatous disease is a serious complication of common variable immunodeficiency (CVID-GD) that occurs in 8–22% o...
Cutting-edge technology and automation in the pathology laboratory
Cutting-edge technology and automation in the pathology laboratory
One of the goals of pathology is to standardize laboratory practices to increase the precision and effectiveness of diagno...
TelePi: an affordable telepathology microscope camera system anyone can build and use
TelePi: an affordable telepathology microscope camera system anyone can build and use
Telepathology facilitates histological diagnoses through sharing expertise between pathologists. However, the associated c...
Prognostic value of HPV-PCR, p16 and p53 immunohistochemical status on local recurrence rate and survival in patients with vulvar squamous cell carcinoma
Prognostic value of HPV-PCR, p16 and p53 immunohistochemical status on local recurrence rate and survival in patients with vulvar squamous cell carcinoma
The primary aim of this study was to assess the association between human papilloma virus (HPV) and p53 expression and loc...
The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms
The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms
Mesenchymal neoplasms with GLI1 alterations have recently been reported in several anatomic locations. Their morphology an...
mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy
mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy
In the spectrum of oncocytic renal neoplasms, a subset of tumors with high-grade-appearing histologic features harboring p...
Pseudoendocrine sarcoma: clinicopathologic, molecular, and epigenetic features of one case
Pseudoendocrine sarcoma: clinicopathologic, molecular, and epigenetic features of one case
Pseudoendocrine sarcoma (PES) is a recently described neoplasm typically arising in paravertebral soft tissues. Histologic...
Expression of CD5 in salivary gland tumors: an ancillary marker for carcinoma showing thymus-like differentiation (CASTLE) of the major salivary gland
Expression of CD5 in salivary gland tumors: an ancillary marker for carcinoma showing thymus-like differentiation (CASTLE) of the major salivary gland
Recently, cases of carcinoma showing thymus-like differentiation (CASTLE) occurring in major salivary glands have been ide...
Solitary fibrous tumours involving the genitourinary tract: a case series in rare locations, highlighting the role of STAT6 immunohistochemistry
Solitary fibrous tumours involving the genitourinary tract: a case series in rare locations, highlighting the role of STAT6 immunohistochemistry
Solitary fibrous tumour (SFT) is a mesenchymal neoplasm with variable behaviour, very rarely involving the genitourinary (...
Large B-cell lymphoma with IRF4 rearrangement: a multi-centric study with focus on potential misleading phenotypes
Large B-cell lymphoma with IRF4 rearrangement: a multi-centric study with focus on potential misleading phenotypes
Large B-cell lymphoma with IRF4 rearrangement (LBCL-IRF4) is a rare lymphoid neoplasm, usually occurring in the pediatric/...
Branchioma: immunohistochemical and molecular genetic study of 23 cases highlighting frequent loss of retinoblastoma 1 immunoexpression
Branchioma: immunohistochemical and molecular genetic study of 23 cases highlighting frequent loss of retinoblastoma 1 immunoexpression
Branchioma is an uncommon benign neoplasm with an adult male predominance, typically occurring in the lower neck region. D...
Validation of Modaplex POLE mutation assay in endometrial carcinoma
Validation of Modaplex POLE mutation assay in endometrial carcinoma
The TCGA-based molecular classification of endometrial cancer has emerged as an important tool to stratify patients accord...
Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Evaluation of B-cell clonality can be challenging in the interpretation of lymphoid infiltrates on tissue sections. Clonal...
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