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Loss of insulin-expressing extra-islet cells in type 1 diabetes is accompanied with increased number of glucagon-expressing extra-islet cells
Loss of insulin-expressing extra-islet cells in type 1 diabetes is accompanied with increased number of glucagon-expressing extra-islet cells
The presence of remaining insulin-positive cells in type 1 diabetes (T1D) is well-known. These cells are part of islets or...
TRPS1 expression in breast angiosarcoma
TRPS1 expression in breast angiosarcoma
Angiosarcoma (AS) of the breast, a rare mesenchymal neoplasm, exhibits distinct forms based on etiological and genetic fea...
An extensive immunohistochemical analysis of 290 ovarian adult granulosa cell tumors with 29 markers
An extensive immunohistochemical analysis of 290 ovarian adult granulosa cell tumors with 29 markers
The current knowledge about the immunohistochemical features of adult granulosa cell tumor (AGCT) is mostly limited to the...
PIT-EASY survey: validation of the European Pituitary Pathology Group proposal for reporting pituitary neuroendocrine tumors
PIT-EASY survey: validation of the European Pituitary Pathology Group proposal for reporting pituitary neuroendocrine tumors
The aim of this multicenter prospective survey called PIT-EASY was to assess the relevance of the European Pituitary Patho...
Endometrial endometrioid adenocarcinoma with a malignant squamous component: is the unusual metastatic pattern unique of these tumors?
Endometrial endometrioid adenocarcinoma with a malignant squamous component: is the unusual metastatic pattern unique of these tumors?
The FIGO scheme is currently applied for tumor grading of endometrioid adenocarcinoma. The current report presents a serie...
Expression of the tumor antigens NY-ESO-1, tyrosinase, MAGE-A3, and TPTE in pediatric and adult melanoma: a retrospective case control study
Expression of the tumor antigens NY-ESO-1, tyrosinase, MAGE-A3, and TPTE in pediatric and adult melanoma: a retrospective case control study
Tumor-associated antigens (TAAs) are potential targets for T cell-based immunotherapy approaches in cutaneous melanoma. BN...
Sclerosing epithelioid fibrosarcoma: a new mesenchymal non-meningothelial tumor involving the central nervous system?
Sclerosing epithelioid fibrosarcoma: a new mesenchymal non-meningothelial tumor involving the central nervous system?
Authors and AffiliationsDepartment of Pathology, Strasbourg University Hospital, 67098, Strasbourg Cedex, FranceThibaut Wo...
Obliteration of liver sinusoids through platelet aggregates associated to extramedullary haematopoiesis in myeloid neoplasms
Obliteration of liver sinusoids through platelet aggregates associated to extramedullary haematopoiesis in myeloid neoplasms
Herein is reported a series of five patients with myeloid neoplasms presenting hepatic complications in whose liver biopsy...
A deep-learning-based model for assessment of autoimmune hepatitis from histology: AI(H)
A deep-learning-based model for assessment of autoimmune hepatitis from histology: AI(H)
Histological assessment of autoimmune hepatitis (AIH) is challenging. As one of the possible results of these challenges, ...
Clear cell adult rhabdomyoma—a rare variant of an unusual tumour
Clear cell adult rhabdomyoma—a rare variant of an unusual tumour
Jiang Z, Zhang M, Huang J et al (2023) Adult-type rhabdomyoma of the thyroid: A case report. Front Oncol 13:1108133Article...
Papillary renal neoplasm with reverse polarity has low frequency of alterations in chromosomes 7, 17, and Y
Papillary renal neoplasm with reverse polarity has low frequency of alterations in chromosomes 7, 17, and Y
In papillary renal neoplasm with reverse polarity (PRNRP), the status of chromosomal copy number alterations, especially c...
Small blue round cell tumor with focal epithelial differentiation harboring a novel YAP1::LEUTX fusion with poor prognosis
Small blue round cell tumor with focal epithelial differentiation harboring a novel YAP1::LEUTX fusion with poor prognosis
Wang X, Liu LL, Li Q et al (2023) Loss of YAP1 C-terminus expression as an ancillary marker for metaplastic thymoma: a pot...
“Aberrant” expression of skeletal muscle markers in neuroendocrine carcinomas: a significant diagnostic pitfall
“Aberrant” expression of skeletal muscle markers in neuroendocrine carcinomas: a significant diagnostic pitfall
In this study, we investigate the expression of muscle markers, including the specific skeletal muscle markers myogenin an...
Multimodal integration of clinic, pathology, and genomics for a rare diagnosis of EBV-positive primary mediastinal large B-cell lymphoma
Multimodal integration of clinic, pathology, and genomics for a rare diagnosis of EBV-positive primary mediastinal large B-cell lymphoma
Alaggio R, Amador C, Anagnostopoulos I et al (2022) The 5th edition of the World Health Organization classification of hae...
Paediatric pancreatic acinar cell carcinoma with a novel SEC31A-BRAF fusion gene
Paediatric pancreatic acinar cell carcinoma with a novel SEC31A-BRAF fusion gene
Paediatric pancreatic acinar cell carcinoma (PACC) presents a diagnostic challenge, often confused with pancreatoblastoma ...
Non-small cell lung carcinoma with clear cell features: a clinicopathologic, immunohistochemical, and molecular study of 31 cases
Non-small cell lung carcinoma with clear cell features: a clinicopathologic, immunohistochemical, and molecular study of 31 cases
Non-small cell lung carcinoma with predominantly clear cell features is a rare histologic presentation of lung carcinoma. ...
Morphology and multiparameter flow cytometry combined for integrated lymphoma diagnosis on small volume samples: possibilities and limitations
Morphology and multiparameter flow cytometry combined for integrated lymphoma diagnosis on small volume samples: possibilities and limitations
The diagnosis of lymphoma relies mainly on clinical examination and laboratory explorations. Among the latter, morphologic...
Neonatal spindle-cell CD34-positive plaque-like tumour: a new entity characterised by NTRK gene fusion
Neonatal spindle-cell CD34-positive plaque-like tumour: a new entity characterised by NTRK gene fusion
Antonescu CR, Dickson BC, Swanson D, Zhang L, Sung YS, Kao YC, Chang WC, Ran L, Pappo A, Bahrami A, Chi P, Fletcher CD (20...
Shared chromosome 21q loss in a mixed subtype renal cell carcinoma: composite or collision tumor?
Shared chromosome 21q loss in a mixed subtype renal cell carcinoma: composite or collision tumor?
Clear cell renal cell carcinoma (CCRCC) and papillary renal cell carcinoma (PRCC) are the two most frequently enc...
Impact of immunohistochemistry staining conditions on the incidence of human epidermal growth factor receptor 2 (HER2)-low breast cancer
Impact of immunohistochemistry staining conditions on the incidence of human epidermal growth factor receptor 2 (HER2)-low breast cancer
We investigated frequencies of HER2-low breast cancer (BC) (immunohistochemistry [IHC] 1+ or 2+ without gene amplification...
Beyond histology: A tissue algorithm predictive of post-surgical recurrence in hepatocellular carcinomas, including TERT promoter mutation
Beyond histology: A tissue algorithm predictive of post-surgical recurrence in hepatocellular carcinomas, including TERT promoter mutation
Surgical resection for hepatocellular carcinoma (HCC) is burdened with a high recurrence rate and a lack of reliable progn...