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Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in several studies with conflicting res...
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular testing in breast cancer gained increasing attention and importance as specific molecular results can tailor not...
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Human epidermal growth factor receptor 2 (HER)-positive breast cancer (BC) is characterized by an aggressive clinical cour...
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
Cancer of unknown primary (CUP) presents a complex diagnostic challenge, characterized by metastatic tumors of unknown tis...
Genomic alterations and diagnosis of renal cancer
Genomic alterations and diagnosis of renal cancer
The application of molecular profiling has made substantial impact on the classification of urogenital tumors. Therefore, ...
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
A liver biopsy is essential for the diagnostic workup of persistent neonatal cholestasis (NC). The differential diagnosis ...
Molecular pathology as basis for timely cancer diagnosis and therapy
Molecular pathology as basis for timely cancer diagnosis and therapy
Precision and personalized therapeutics have witnessed significant advancements in technology, revolutionizing the capabil...
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Medical oncology is rapidly evolving with the implementation of personalized, targeted therapies. Advances in molecular di...
Correction to: Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Correction to: Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Pathology Unit, Department of Molecular and Translational Medicine-DMMT, University of Brescia, Brescia, ItalyLuisa Lorenz...
The HER2-low revolution in gynecological oncology: could it be a realistic emerging challenge?
The HER2-low revolution in gynecological oncology: could it be a realistic emerging challenge?
Ovarian clear cell carcinoma (OCCC) is a high-grade adenocarcinoma, often endometriosis related, generally diagnosed in yo...
Correction to: Voices from the past: results of the ESP history of pathology working group survey on pathology museums
Correction to: Voices from the past: results of the ESP history of pathology working group survey on pathology museums
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons
STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons
Granulomatous disease is a serious complication of common variable immunodeficiency (CVID-GD) that occurs in 8–22% o...
Cutting-edge technology and automation in the pathology laboratory
Cutting-edge technology and automation in the pathology laboratory
One of the goals of pathology is to standardize laboratory practices to increase the precision and effectiveness of diagno...
TelePi: an affordable telepathology microscope camera system anyone can build and use
TelePi: an affordable telepathology microscope camera system anyone can build and use
Telepathology facilitates histological diagnoses through sharing expertise between pathologists. However, the associated c...
The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms
The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms
Mesenchymal neoplasms with GLI1 alterations have recently been reported in several anatomic locations. Their morphology an...
Pseudoendocrine sarcoma: clinicopathologic, molecular, and epigenetic features of one case
Pseudoendocrine sarcoma: clinicopathologic, molecular, and epigenetic features of one case
Pseudoendocrine sarcoma (PES) is a recently described neoplasm typically arising in paravertebral soft tissues. Histologic...
Solitary fibrous tumours involving the genitourinary tract: a case series in rare locations, highlighting the role of STAT6 immunohistochemistry
Solitary fibrous tumours involving the genitourinary tract: a case series in rare locations, highlighting the role of STAT6 immunohistochemistry
Solitary fibrous tumour (SFT) is a mesenchymal neoplasm with variable behaviour, very rarely involving the genitourinary (...
Large B-cell lymphoma with IRF4 rearrangement: a multi-centric study with focus on potential misleading phenotypes
Large B-cell lymphoma with IRF4 rearrangement: a multi-centric study with focus on potential misleading phenotypes
Large B-cell lymphoma with IRF4 rearrangement (LBCL-IRF4) is a rare lymphoid neoplasm, usually occurring in the pediatric/...
Branchioma: immunohistochemical and molecular genetic study of 23 cases highlighting frequent loss of retinoblastoma 1 immunoexpression
Branchioma: immunohistochemical and molecular genetic study of 23 cases highlighting frequent loss of retinoblastoma 1 immunoexpression
Branchioma is an uncommon benign neoplasm with an adult male predominance, typically occurring in the lower neck region. D...
Validation of Modaplex POLE mutation assay in endometrial carcinoma
Validation of Modaplex POLE mutation assay in endometrial carcinoma
The TCGA-based molecular classification of endometrial cancer has emerged as an important tool to stratify patients accord...
Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Evaluation of B-cell clonality can be challenging in the interpretation of lymphoid infiltrates on tissue sections. Clonal...