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Recently Described and Molecularly Defined Head and Neck Tumors
Recently Described and Molecularly Defined Head and Neck Tumors
*Department of Pathology, Charles University, Faculty of Medicine in Plzen †Bioptic Laboratory Ltd., Plzen, C...
Microsecretory Adenocarcinoma of Salivary Glands
Microsecretory Adenocarcinoma of Salivary Glands
Salivary gland classification has benefitted immensely from the growing field of molecular diagnosti
Melanoma and Glioblastoma—Not a Serendipitous Association
Melanoma and Glioblastoma—Not a Serendipitous Association
Recently, we came across a patient with malignant melanoma and primary glioblastoma. Given this, we
SWI/SNF-deficient Malignancies: Optimal Candidates for Immune-oncological Therapy?
SWI/SNF-deficient Malignancies: Optimal Candidates for Immune-oncological Therapy?
Inactivation of different subunits of the SWItch/sucrose nonfermentable (SWI/SNF) chromatin remodeli
SWI/SNF-deficient Sinonasal Carcinomas
SWI/SNF-deficient Sinonasal Carcinomas
The classification of poorly differentiated sinonasal carcinomas and their nonepithelial mimics has
Approach to FNA of Thyroid Gland Cysts
Approach to FNA of Thyroid Gland Cysts
Fine needle aspiration is a well-known procedure for the diagnosis and management of thyroid lesions
Histopathologic Features of Adrenal Cortical Carcinoma
Histopathologic Features of Adrenal Cortical Carcinoma
Adrenal cortical carcinoma (ACC) is a rare and aggressive malignancy that poses challenging issues r
The Classic, the Trendy, and the Refashioned: A Primer for Pathologists on What Is New in Familial Endocrine Tumor Syndromes
The Classic, the Trendy, and the Refashioned: A Primer for Pathologists on What Is New in Familial Endocrine Tumor Syndromes
Familial endocrine tumor syndromes are continuously expanding owing to the growing role of genetic t
Peritoneal Mesothelioma—An Update
Peritoneal Mesothelioma—An Update
A remarkable amount of new information has been generated on peritoneal mesothelioma (PeM), ranging
IDH2-Mutated Sinonasal Tumors: A Review
IDH2-Mutated Sinonasal Tumors: A Review
Introduction: Genetic profiling has caused an explosion in the subclassification of sinonasal mal
Special Issue on Neuroendocrine Tumors: Updates on Classification Systems, Streamlining Diagnosis, and Emphasis on Molecular Signatures in Neuroendocrine Neoplasms
Special Issue on Neuroendocrine Tumors: Updates on Classification Systems, Streamlining Diagnosis, and Emphasis on Molecular Signatures in Neuroendocrine Neoplasms
Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA ...
Cancer Immunology: Immune Escape of Tumors—Expression and Regulation of HLA Class I Molecules and Its Role in Immunotherapies
Cancer Immunology: Immune Escape of Tumors—Expression and Regulation of HLA Class I Molecules and Its Role in Immunotherapies
The addition of “avoiding immune destruction” to the hallmarks of cancer demonstrated the importance
Advances in Adrenal and Extra-adrenal Paraganglioma: Practical Synopsis for Pathologists
Advances in Adrenal and Extra-adrenal Paraganglioma: Practical Synopsis for Pathologists
Adrenal paraganglioma (or “pheochromocytoma”) and extra-adrenal paraganglioma, collectively abbrevia
Approach to FNA of Pancreatic Cysts
Approach to FNA of Pancreatic Cysts
Pancreatic cysts are increasingly detected on imaging studies. Accurate determination of the type of
DEK::AFF2 Fusion Carcinomas of Head and Neck
DEK::AFF2 Fusion Carcinomas of Head and Neck
A novel DEK::AFF2 fusion carcinoma was recently described in 29 patients who originally presented wi
Imaging of Malignant Pleural, Pericardial, and Peritoneal Mesothelioma
Imaging of Malignant Pleural, Pericardial, and Peritoneal Mesothelioma
Malignant mesothelioma is a rare tumor arising from the mesothelial cells that line the pleura, peri
Immunotherapy in Genitourinary Cancers: Role of Surgical Pathologist for Detection of Immunooncologic Predictive Factors
Immunotherapy in Genitourinary Cancers: Role of Surgical Pathologist for Detection of Immunooncologic Predictive Factors
Genitourinary malignancies include a broad spectrum of distinct tumor entities occurring in the kidn
Visceral Pleural Invasion in Lung Cancer: Recognizing Histologic Parameters That Impact Staging and Prognosis
Visceral Pleural Invasion in Lung Cancer: Recognizing Histologic Parameters That Impact Staging and Prognosis
Abstract: Visceral pleural involvement (VPI) is a critical component in the staging of non-small
Blue Nevi and Related Lesions: A Review Highlighting Atypical and Newly Described Variants, Distinguishing Features and Diagnostic Pitfalls
Blue Nevi and Related Lesions: A Review Highlighting Atypical and Newly Described Variants, Distinguishing Features and Diagnostic Pitfalls
Blue nevi and related entities are a heterogenous group of congenital and acquired melanocytic tumor
Advances in Thyroid Pathology: High Grade Follicular cell-derived Thyroid Carcinoma and Anaplastic Thyroid Carcinoma
Advances in Thyroid Pathology: High Grade Follicular cell-derived Thyroid Carcinoma and Anaplastic Thyroid Carcinoma
In the upcoming World Health Organization fifth edition classification of endocrine tumors, there we
The Pathology of Endometriosis: A Survey of the Many Faces of a Common Disease Emphasizing Diagnostic Pitfalls and Unusual and Newly Appreciated Aspects
The Pathology of Endometriosis: A Survey of the Many Faces of a Common Disease Emphasizing Diagnostic Pitfalls and Unusual and Newly Appreciated Aspects
Although the histologic diagnosis of endometriosis is usually straightforward, many diagnostic probl
Advances and Updates in Parathyroid Pathology
Advances and Updates in Parathyroid Pathology
Hyperparathyroidism is a common endocrine disorder characterized by elevated levels of parathyroid h
Neuroendocrine Neoplasms of the Pancreas: Diagnostic Challenges and Practical Approach
Neuroendocrine Neoplasms of the Pancreas: Diagnostic Challenges and Practical Approach
Most pancreatic neuroendocrine neoplasms are slow-growing, and the patients may survive for many yea
Follicular Neoplasm of Thyroid Revisited: Current Differential Diagnosis and the Impact of Molecular Testing
Follicular Neoplasm of Thyroid Revisited: Current Differential Diagnosis and the Impact of Molecular Testing
The diagnosis of “follicular neoplasm” (FN) in thyroid cytopathology has a long history that origina
An Overview of Pituitary Neuroendocrine Tumors (PitNET) and Algorithmic Approach to Diagnosis
An Overview of Pituitary Neuroendocrine Tumors (PitNET) and Algorithmic Approach to Diagnosis
The diagnostic algorithm and nomenclature of pituitary neuroendocrine tumors have evolved over the p
From Malignant Thyroid Teratoma to Thyroblastoma: Evolution of a Newly-recognized DICER1-associated Malignancy
From Malignant Thyroid Teratoma to Thyroblastoma: Evolution of a Newly-recognized DICER1-associated Malignancy
Thyroblastoma is a novel thyroid malignancy included in the 5th Edition WHO Classification of Endocr
Small Biopsy and Cytology of Pulmonary Neuroendocrine Neoplasms: Brief Overview of Classification, Immunohistochemistry, Molecular Profiles, and World Health Organization Updates
Small Biopsy and Cytology of Pulmonary Neuroendocrine Neoplasms: Brief Overview of Classification, Immunohistochemistry, Molecular Profiles, and World Health Organization Updates
Pulmonary neuroendocrine neoplasms comprise ~20% of all lung tumors. Typical carcinoid, atypical car
Salivary Gland Intraductal Carcinoma: How Do 183 Reported Cases Fit Into a Developing Classification
Salivary Gland Intraductal Carcinoma: How Do 183 Reported Cases Fit Into a Developing Classification
Salivary gland intraductal carcinoma (IDC) is a very uncommon group of neoplasms. Many names, variat
Updates and Proposed Diagnostic Approach to Psoriasiform Dermatoses
Updates and Proposed Diagnostic Approach to Psoriasiform Dermatoses
Psoriasiform dermatoses represent a wide array of skin diseases commonly encountered by clinicians a
Mucinous Proliferations of the Uterine Corpus: Comprehensive Appraisal of an Evolving Spectrum of Neoplasms
Mucinous Proliferations of the Uterine Corpus: Comprehensive Appraisal of an Evolving Spectrum of Neoplasms
A variety of endometrial lesions may contain mucinous cells. Herein, the author reviews the literatu
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