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Effect of remimazolam toluene sulfonate on the cognitive function of juveniles and its mechanism of action
Effect of remimazolam toluene sulfonate on the cognitive function of juveniles and its mechanism of action
Remimazolam is a new benzodiazepine. Currently, it remains unclear how repeated exposure to remimazolam affects the cognit...
Predicting stroke severity of patients using interpretable machine learning algorithms
Predicting stroke severity of patients using interpretable machine learning algorithms
Stroke is a significant global health concern, ranking as the second leading cause of death and placing a substantial fina...
A predictive and prognostic model for metastasis risk and prognostic factors in gastrointestinal signet ring cell carcinoma
A predictive and prognostic model for metastasis risk and prognostic factors in gastrointestinal signet ring cell carcinoma
This study aimed to predict metastasis risk and identify prognostic factors of gastrointestinal signet ring cell carcinoma...
Acute hyperglycemia exacerbates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy by mediating the ChREBP/HIF-1α pathway
Acute hyperglycemia exacerbates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy by mediating the ChREBP/HIF-1α pathway
Delirium is a prominent symptom of sepsis-associated encephalopathy (SAE) and is highly prevalent in septic patients hospi...
Inflammatory index is a promising biomarker for maintenance hemodialysis patients with cardiovascular disease
Inflammatory index is a promising biomarker for maintenance hemodialysis patients with cardiovascular disease
Maintenance hemodialysis (MHD) patients are at a higher risk of cardiovascular disease (CVD), a common complication and le...
The hemoglobin, albumin, lymphocyte, and platelet (HALP) score is associated with severe renal tubular atrophy/interstitial fibrosis in IgA nephropathy
The hemoglobin, albumin, lymphocyte, and platelet (HALP) score is associated with severe renal tubular atrophy/interstitial fibrosis in IgA nephropathy
This study was performed to investigate the relationship between hemoglobin, albumin, lymphocyte and platelet (HALP) score...
Improving methylmalonic acidemia (MMA) screening and MMA genotype prediction using random forest classifier in two Chinese populations
Improving methylmalonic acidemia (MMA) screening and MMA genotype prediction using random forest classifier in two Chinese populations
Methylmalonic acidemia (MMA) is one of the most common hereditary organic acid metabolism disorders that endangers the liv...
Genes to therapy: a comprehensive literature review of whole-exome sequencing in neurology and neurosurgery
Genes to therapy: a comprehensive literature review of whole-exome sequencing in neurology and neurosurgery
Whole-exome sequencing (WES), a ground-breaking technology, has emerged as a linchpin in neurology and neurosurgery, offer...
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin
A single nucleotide polymorphism (SNP) is a variation in the DNA sequence that results from the alteration of a single nuc...
Homocysteine aggravates intestinal inflammation through promotion of 5-LOX and COX-2 in IBD
Homocysteine aggravates intestinal inflammation through promotion of 5-LOX and COX-2 in IBD
Homocysteine (Hcy) is a pro-inflammatory molecule that has the potential to induce oxidative damage to cells and stimulate...
Correction: Three-dimensional visual technique based on CT lymphography data combined with methylene blue in endoscopic sentinel lymph node biopsy for breast cancer
Correction: Three-dimensional visual technique based on CT lymphography data combined with methylene blue in endoscopic sentinel lymph node biopsy for breast cancer
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Dosimetric comparison of multiple SBRT delivery platforms for pancreatic cancer
Dosimetric comparison of multiple SBRT delivery platforms for pancreatic cancer
Stereotactic body radiation therapy (SBRT) has been widely used for pancreatic cancer. However, there is still a lack of s...
Long-term outcomes of spinal fusion in adolescent idiopathic scoliosis: a literature review
Long-term outcomes of spinal fusion in adolescent idiopathic scoliosis: a literature review
Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity in the younger population. The surgical ...
Poria cocos inhibits the invasion, migration, and epithelial–mesenchymal transition of gastric cancer cells by inducing ferroptosis in cells
Poria cocos inhibits the invasion, migration, and epithelial–mesenchymal transition of gastric cancer cells by inducing ferroptosis in cells
Gastric cancer (GC) is one of the most prevalent malignant tumors of the digestive system. The advanced metastasis of gast...
Non-linear connection between the triglyceride–glucose index and prediabetes risk among Chinese adults: a secondary retrospective cohort study
Non-linear connection between the triglyceride–glucose index and prediabetes risk among Chinese adults: a secondary retrospective cohort study
The triglyceride–glucose (TyG) index has garnered recognition as a surrogate marker for insulin resistance, a pivota...
Expression of NLRP3 in serum and induced sputum of children with asthma and their relationship with disease severity
Expression of NLRP3 in serum and induced sputum of children with asthma and their relationship with disease severity
The aim of this cross-sectional study is to investigate the levels of NLRP3 in the serum and induced sputum of children wi...
Prediction of recurrence-free survival and risk factors of sinonasal inverted papilloma after surgery by machine learning models
Prediction of recurrence-free survival and risk factors of sinonasal inverted papilloma after surgery by machine learning models
Our research aims to construct machine learning prediction models to identify patients proned to recurrence after inverted...
Analyses of gingival papilla blood flow via color doppler flow imaging and micro-flow imaging in patients with advanced periodontitis: a clinical pilot study
Analyses of gingival papilla blood flow via color doppler flow imaging and micro-flow imaging in patients with advanced periodontitis: a clinical pilot study
Research investigating the potential link between gingival microvascular blood flow and inflammatory status is scarce. Thi...
Application of targeted drug delivery by cell membrane-based biomimetic nanoparticles for inflammatory diseases and cancers
Application of targeted drug delivery by cell membrane-based biomimetic nanoparticles for inflammatory diseases and cancers
Drug-carrying nanoparticles can be recognized and captured by macrophages and cleared away by the immune system, resulting...
Comparing the effects of oral sucrose and kangaroo mother care on selected physiological variables and pain resulting from venipuncture in premature newborns admitted to neonatal intensive care units
Comparing the effects of oral sucrose and kangaroo mother care on selected physiological variables and pain resulting from venipuncture in premature newborns admitted to neonatal intensive care units
Premature newborns admitted to neonatal intensive care units (NICUs) undergo numerous painful interventions during care an...
Potential role of predictive models in assessment of liver inflammation in patients with hepatocellular carcinoma: a two-center cohort study
Potential role of predictive models in assessment of liver inflammation in patients with hepatocellular carcinoma: a two-center cohort study
Hepatic inflammation in patients with hepatocellular carcinoma (HCC) remains unclear. This study aimed to construct a clin...
Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression
Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression
Several tetraspanin (TSPAN) proteins have been implicated in tumorigenesis and disease progression. However, the precise f...
Results of bracing adolescent idiopathic scoliosis in the context of clinical practice and the Scoliosis Research Society’s criteria: 5-year observational study from a German orthopaedic university hospital
Results of bracing adolescent idiopathic scoliosis in the context of clinical practice and the Scoliosis Research Society’s criteria: 5-year observational study from a German orthopaedic university hospital
Brace therapy’s influence on adolescent idiopathic scoliosis’s (AIS) natural course is inconclusive. Brace-tre...
Causal effect of gut microbiota on occurrence of herpes zoster and postherpetic neuralgia, and role of Tyzzerella 3
Causal effect of gut microbiota on occurrence of herpes zoster and postherpetic neuralgia, and role of Tyzzerella 3
Previous research has established connections between gut microbiota, immune modulation, and several virus-related disease...
Enhanced recovery after surgery (ERAS) improves outcomes in elderly patients undergoing short-level lumbar fusion surgery: a retrospective study of 333 cases
Enhanced recovery after surgery (ERAS) improves outcomes in elderly patients undergoing short-level lumbar fusion surgery: a retrospective study of 333 cases
Degenerative lumbar disease significantly impairs the quality of life in elderly individuals, with short-segment lumbar de...
Surgical treatment of long-term epilepsy-associated tumors guided by stereoelectroencephalography
Surgical treatment of long-term epilepsy-associated tumors guided by stereoelectroencephalography
Accurate detection and resection of the epileptogenic zone (EZ) in patients with long-term epilepsy-associated tumors (LEA...
High levels of serum hypersensitive C-reactive protein are associated with non-alcoholic fatty liver disease in non-obese people: a cross-sectional study
High levels of serum hypersensitive C-reactive protein are associated with non-alcoholic fatty liver disease in non-obese people: a cross-sectional study
Non-alcoholic fatty liver disease (NAFLD) and obesity have become one of the most common chronic diseases, and the global ...
Metabolic reprogramming of macrophages in the context of type 2 diabetes
Metabolic reprogramming of macrophages in the context of type 2 diabetes
Type 2 diabetes (T2D) is associated with insulin resistance and progressive dysfunction of β-pancreatic cells, leadin...
Identification of cuproptosis-related genes in Alzheimer’s disease based on bioinformatic analysis
Identification of cuproptosis-related genes in Alzheimer’s disease based on bioinformatic analysis
To explore the role of cuproptosis in Alzheimer’s disease (AD). An AD-related microarray dataset was downloaded from...
Predicting 3-month poor functional outcomes of acute ischemic stroke in young patients using machine learning
Predicting 3-month poor functional outcomes of acute ischemic stroke in young patients using machine learning
Prediction of short-term outcomes in young patients with acute ischemic stroke (AIS) may assist in making therapy decision...
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