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Steroidal saponin SSPH I induces ferroptosis in HepG2 cells via regulating iron metabolism
Steroidal saponin SSPH I induces ferroptosis in HepG2 cells via regulating iron metabolism
Hepatocellular carcinoma (HCC) is a common type of solid liver carcinoma. Regulating ferroptosis is important for the trea...
Gold cluster encapsulated liposomes: theranostic agent with stimulus triggered release capability
Gold cluster encapsulated liposomes: theranostic agent with stimulus triggered release capability
Cancer is a major cause of death worldwide. Cancer-resistant to chemo or radiotherapy treatment is a challenge that could ...
Anticancer activity of lycopene in HT-29 colon cancer cell line
Anticancer activity of lycopene in HT-29 colon cancer cell line
An inverse association between serum lycopene levels and the risk of cancers has been pointed out by many prospective and ...
The impact of hypoxia on extracellular vesicle secretome profile of cancer
The impact of hypoxia on extracellular vesicle secretome profile of cancer
Extracellular vesicles (EVs) are emerging as key mediators of cell-to-cell communications and signal transporters between ...
2,4-Dipropylphloroglucinol inhibits the growth of human lung and colorectal cancer cells through induction of apoptosis
2,4-Dipropylphloroglucinol inhibits the growth of human lung and colorectal cancer cells through induction of apoptosis
Scientists are finding the most effective chemotherapeutic agents for the treatment of cancer. In the present study, we ev...
Phospho PTEN mediated dephosphorylation of mitotic kinase PLK1 and Aurora Kinase A prevents aneuploidy and preserves genomic stability
Phospho PTEN mediated dephosphorylation of mitotic kinase PLK1 and Aurora Kinase A prevents aneuploidy and preserves genomic stability
PTEN, dual phosphatase tumor suppressor protein, is found to be frequently mutated in various cancers. Post-translational ...
Electrochemical therapy (EChT) of cancer tumor with an external anode, a way to achieve pathological complete response
Electrochemical therapy (EChT) of cancer tumor with an external anode, a way to achieve pathological complete response
There is a critical need for re-evaluation of electrochemical therapy (EChT) approaches of solid tumors to address the cha...
ACADL suppresses PD-L1 expression to prevent cancer immune evasion by targeting Hippo/YAP signaling in lung adenocarcinoma
ACADL suppresses PD-L1 expression to prevent cancer immune evasion by targeting Hippo/YAP signaling in lung adenocarcinoma
Lung cancer is the leading cause of cancer-related death. Cancer immune evasion is a key barrier in the treatment of lung ...
Nutrition care is an integral part of patient-centred medical care: a European consensus
Nutrition care is an integral part of patient-centred medical care: a European consensus
While healthcare is becoming more patient-centred, evidence-based nutrition interventions are still not accessibl...
Insights into ovarian cancer: chemo-diversity, dose depended toxicities and survival responses
Insights into ovarian cancer: chemo-diversity, dose depended toxicities and survival responses
Ovarian cancer has been one of the serious concerns for female health and medicinal practitioner all over the world. The w...
Modeling cancer’s ecological and evolutionary dynamics
Modeling cancer’s ecological and evolutionary dynamics
In this didactic paper, we present a theoretical modeling framework, called the G-function, that integrates both the ecolo...
PD-1/PD-L1 blockade inhibits epithelial-mesenchymal transition and improves chemotherapeutic response in breast cancer
PD-1/PD-L1 blockade inhibits epithelial-mesenchymal transition and improves chemotherapeutic response in breast cancer
Therapies targeting the PD-1/PD-L1 axis have recently been implemented for triple negative breast cancer (TNBC) management...
Immune checkpoint inhibitor using in cases with gestational trophoblastic diseases
Immune checkpoint inhibitor using in cases with gestational trophoblastic diseases
Gestational trophoblastic neoplasias (GTNs) are chemosensitive disorders with very high cure rates. However, individuals w...
Design of a potential Sema4A-based multi-epitope vaccine to combat triple-negative breast cancer: an immunoinformatic approach
Design of a potential Sema4A-based multi-epitope vaccine to combat triple-negative breast cancer: an immunoinformatic approach
Immunotherapy is revamping the therapeutic strategies for TNBC owing to its higher mutational burden and tumour-associated...
Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma
Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma
Glioblastoma (GBM) is the most frequent brain cancer and more lethal than other cancers. Characteristics of this cancer ar...
Adjuvant treatment of surgically treated bone metastasis patients: association with hospital characteristics and trends over time
Adjuvant treatment of surgically treated bone metastasis patients: association with hospital characteristics and trends over time
Patients with metastatic disease of the bone (MDB) often require surgical stabilization; however, there is not widespread ...
Relationship between glioblastoma multiforme (GBM) and Alzheimer’s disease (AD): is there any reporting bias?
Relationship between glioblastoma multiforme (GBM) and Alzheimer’s disease (AD): is there any reporting bias?
Seddighi S, Houck AL, Rowe JB, Pharoah PDP. Evidence of a causal association between cancer and Alzheimer’s disease: a men...
Identification of potential tumor antigens and immune subtypes for lung adenocarcinoma
Identification of potential tumor antigens and immune subtypes for lung adenocarcinoma
In lung adenocarcinoma (LUAD), tumor antigens and immune phenotypes are important for cancer immunotherapy. This study aim...
MORC2 and MAX contributes to the expression of glycolytic enzymes, breast cancer cell proliferation and migration
MORC2 and MAX contributes to the expression of glycolytic enzymes, breast cancer cell proliferation and migration
Cancer cell proliferation is a high energy demanding process, where the cancer cells acquire energy by high rates of glyco...
The in vitro treatment of mesenchymal stem cells for colorectal cancer cells
The in vitro treatment of mesenchymal stem cells for colorectal cancer cells
Colorectal cancer is the most common tumor of the gastrointestinal system. The conventional treatment options for colorect...
Propionate-producing Veillonella parvula regulates the malignant properties of tumor cells of OSCC
Propionate-producing Veillonella parvula regulates the malignant properties of tumor cells of OSCC
Oral squamous cell carcinoma (OSCC), main head and neck squamous cell carcinomas (HNSCCs), remains a global health concern...
The past, present, and future of immunotherapy for colorectal cancer
The past, present, and future of immunotherapy for colorectal cancer
Colorectal cancer is prevalent worldwide, with various factors influencing the survival rate of late-stage metastatic case...
Upregulation of TUBG1 expression promotes hepatocellular carcinoma development
Upregulation of TUBG1 expression promotes hepatocellular carcinoma development
Tubulin γ-1 (TUBG1) is a highly conserved component of the centrosome and its deregulation is involved in the develop...
Function of TRPC1 in modulating hepatocellular carcinoma progression
Function of TRPC1 in modulating hepatocellular carcinoma progression
The liver is the main organ of metabolism in the human body, and it is easy to suffer from hepatitis, cirrhosis, liver can...
NLRP3 inflammasome activation By 17β-estradiol is a potential therapeutic target in hepatocellular carcinoma treatment
NLRP3 inflammasome activation By 17β-estradiol is a potential therapeutic target in hepatocellular carcinoma treatment
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it mostly arises as a consequence of persi...
Clinical application of liquid biopsy in endometrial carcinoma
Clinical application of liquid biopsy in endometrial carcinoma
Endometrial cancer is the most common gynecological malignant tumor in women, and its morbidity and mortality have been ri...
Epidemiological trends and risk factors of gynecological cancers: an update
Epidemiological trends and risk factors of gynecological cancers: an update
Gynecological cancers, the most common cancer among women worldwide, disrupt the function of women’s reproductive sy...
Photodynamic therapy in oral cancer: a review of clinical studies
Photodynamic therapy in oral cancer: a review of clinical studies
A significant mortality rate is associated with oral cancer, particularly in cases of late-stage diagnosis. Since the last...