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Characterization of the volatile profile and its estrogenic activity in Kadsura coccinea fruit
Kadsura coccinea (Lem.) A. C. Smith is a perennial evergreen vine of the family Schisandraceae. It is cultivated mainly in...
Traditional Chinese Medicine Danzhi qing'e decoction inhibits inflammation-associated prostatic hyperplasia via inactivation of ERK1/2 signal pathway
Benign prostatic hyperplasia (BPH) is a progressive disease in elderly men characterized by the enlargement of prostate pe...
The potential antidiabetic properties of green and purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins
Ethnopharmacological relevanceTea (Camellia sinensis) has been consumed for centuries as traditional medicine for various ...
Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats
Intracerebral hemorrhage (ICH) is a non-traumatic intraparenchymal hemorrhage causing high mortality and poor outcomes. Th...
Efficacy and safety of Chinese herbal medicine children's Zibei Xuanfei syrup in treating acute trachea-bronchitis with wind-heat invading lung syndrome: A randomized, double-blind, multicentre, controlled trial
Acute trachea-bronchitis (ATB) is an acute inflammation of the trachea bronchial mucosa caused by infection, physical or c...
Ethyl palmitate, an anti-chikungunya virus principle from Sauropus androgynus, a medicinal plant used to alleviate fever in ethnomedicine
Chikungunya virus (CHIKV) has had a major impact on human health since its resurgence in 2005 (Staples et al., 2009). It i...
Iridoids from Morinda lucida, (Benth.) Rubiaceae, produced analgesic and anti-inflammatory activities via agonism at the kappa and delta opioid receptors, inhibition of COX-2 besides elevation of CAT and SOD activities
Pain, the commonest symptom which patients complain about, is a sensory and perceptual occurrence which causes suffering a...
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis
Autoimmune hepatitis (AIH) is a complex immune-mediated inflammatory liver disease of unknown cause that can affect people...
Estrogenic and anti-amnesic potential of Millettia griffoniana Baill. (Fabaceae) ethanolic extract on scopolamine-induced memory impairment in ovariectomized Wistar rats
Estrogens are female sex hormones produced by various tissues in the body, the main endogenous source being the ovaries (A...
Sanwei DouKou Decoction ameliorate Alzheimer disease by increasing endogenous neural stem cells proliferation through the Wnt/β-catenin signalling pathway
Alzheimer's Disease (AD) is a chronic neurodegenerative disease characterized by cognitive and motor impairment, and the a...
In silico molecular modeling, neuro-behavioral profile, and toxicity assessment of the essential oil of Ferula gummosa Boiss. as an anti-seizure agent
Epilepsy is a chronic disease with numerous physical, psychological, cognitive, social, and economic implications, charact...
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway
Acute kidney disease (AKI) is a syndrome with high mortality, characterized by abrupt loss of kidney function within hours...
Evaluation of the gastroprotective and ulcer healing properties by Fridericia chica (Bonpl.) L.G. Lohmann hydroethanolic extract of leaves
Peptic ulcer disease (PUD) is one of the major gastrointestinal illnesses with rising incidence and prevalence globally. I...
Glycolipid-enriched fraction of Osmanthus fragrans inhibits LPS-induced expression of inflammatory genes, COX-2, E-selectin, and Interleukin-8
Ethnopharmacological relevanceOsmanthus fragrans Lour. is a small ornamental tree native to the Southeastern parts of Chin...
ErZhiFormula prevents UV-induced skin photoaging by Nrf2/HO-1/NQO1 signaling: An in vitro and in vivo studies
Skin aging is generally divided into two categories: endogenous and exogenous (Dreno et al., 2016; Mousavi et al., 2021). ...
UPLC-QTOF-MS/MS-based metabolomic approach and gastroprotective effect of two chemotypes of Egletes viscosa (L.) less. against ethanol-induced gastric ulcer in mice
Peptic ulcer is an acid-induced lesion of the digestive tract located mainly in the stomach or duodenum, resulting in muco...
The aqueous extracts of Ageratum conyzoides inhibit inflammation by suppressing NLRP3 inflammasome activation
Inflammasomes are cytosolic multiprotein complexes characterized by sensor proteins such as AIM2, IFI16, and various NOD-l...
Involvement of p38 MAPK/cPLA2 and arachidonic acid metabolic pathway in Shengmai injection-induced pseudo-allergic reactions
Shengmai injection (SMI) is a well-known Chinese tonifying medicine. Intravenous SMI was prepared using purified ginseng, ...
TMT quantitative proteomics and network pharmacology reveal the mechanism by which asiaticoside regulates the JAK2/STAT3 signaling pathway to inhibit peritoneal fibrosis
Peritoneal dialysis (PD) is one of the main measures of alternative therapy for end-stage renal disease (ESRD). In recent ...
Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation
Systemic lupus erythematosus (SLE) is a typical autoimmune illness marked by abnormalities in the innate and adaptive immu...
Anti-inflammatory effects of Peucedanum japonicum Thunberg leaves extract in Lipopolysaccharide-stimulated RAW264.7 cells
Inflammatory reactions play an important role in maintaining health as the body's defense mechanism that recognizes and el...
Weierning, a Chinese patent medicine, improves chronic atrophic gastritis with intestinal metaplasia
Chronic atrophic gastritis (CAG) is a gastric disease with pathological characteristics of abnormal glands of the gastric ...
Anti-inflammatory, anti-nociceptive and anti-pyretic activities of Cenchrus ciliaris L.
Inflammation is a protective response of a body, associated with the activation of immune system in a response to the vari...
A homogeneous Lonicera japonica polysaccharide alleviates atopic dermatitis by promoting Nrf2 activation and NLRP3 inflammasome degradation via p62
Atopic dermatitis (AD) is one of the most common chronic inflammatory diseases, affecting over 20% of children and 10% of ...
Cordyceps proteins alleviate lupus nephritis through modulation of the STAT3/mTOR/NF-кB signaling pathway
Systemic lupus erythematosus (SLE) is a representative systemic autoimmune disease, leading to multiple organs damage (Alm...
Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression
Depression is a major psychiatric disease in the 21st century (Rehm and Shield, 2019). Depression is caused by a combinati...
Ganoderma lucidum polysaccharides improve lipid metabolism against high-fat diet-induced dyslipidemia
In the modern society, the unhealthy lifestyle, such as excess calorie intake and lessened physical exercise contribute to...
Sparganii Rhizoma alleviates pulmonary fibrosis by inhibiting fibroblasts differentiation and epithelial-mesenchymal transition mediated by TGF-β1/ Smad2/3 pathway
Pulmonary fibrosis (PF) is a fatal and irreversible disease of the respiratory system. It is an end-stage pathological cha...
Protective effect of Nardostachys jatamansi extract against lithium-pilocarpine-induced spontaneous recurrent seizures and associated cardiac irregularities in a rat model
Epilepsy is a chronic neurological condition presented by seizures due to abnormal neuronal firing. It dramatically affect...
Qingdai Decoction suppresses prostate cancer growth in lethal-stage prostate cancer models
Yi-Shen-Hua-Shi (YSHS) granule is an effective prescription widely used in traditional Chinese medicine to treat diabetic ...
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