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Panax notoginseng saponins inhibits oxidative stress- induced human nucleus pulposus cell apoptosis and delays disc degeneration in vivo and in vitro
Panax notoginseng saponins inhibits oxidative stress- induced human nucleus pulposus cell apoptosis and delays disc degeneration in vivo and in vitro
Ethnopharmacological relevancePanax notoginseng (Burk) F. H. Chen has been a popular traditional Chinese medicine with a l...
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE−/− mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE−/− mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
Atherosclerosis (AS) is the main cause of cardiovascular diseases (CVDs); over 75% of events of acute coronary syndrome ar...
Ruyong formula improves thymus function of CUMS-stimulated breast cancer mice
Ruyong formula improves thymus function of CUMS-stimulated breast cancer mice
Ethnopharmacological relevanceRuyong Formula (RYF) is a famous Chinese herbal formula composed of 10 traditional Chinese h...
An innovative processing driven efficient transformation of rare ginsenosides enhances anti-platelet aggregation potency of notoginseng by integrated analyses of processing-(chemical) profiling-pharmacodynamics
An innovative processing driven efficient transformation of rare ginsenosides enhances anti-platelet aggregation potency of notoginseng by integrated analyses of processing-(chemical) profiling-pharmacodynamics
Processing is a traditional pharmaceutical technology that aimed at enhancing the efficacy and/or reducing the toxicity of...
In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill
In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill
Aloe barbadensis Mill. (Aloe vera) is a homology of medicine and food plant from Liliaceae family, which has been extensiv...
Gleditsiae sinensis fructus Pills combined with Jujubae fructus attenuate chronic bronchitis via regulation of AGE-RAGE signaling pathway
Gleditsiae sinensis fructus Pills combined with Jujubae fructus attenuate chronic bronchitis via regulation of AGE-RAGE signaling pathway
CB is a common respiratory disease characterized by cough and sputum with unclear etiology. The onset lasts over three mon...
Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway
Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway
Depression is a common mood disorder, mostly manifested as low mood, lack of interest, and often self-harm and even suicid...
Shen-Ling-Bai-Zhu-San alleviates the imbalance of intestinal homeostasis in dextran sodium sulfate-induced colitis mice by regulating gut microbiota and inhibiting the NLRP3 inflammasome activation
Shen-Ling-Bai-Zhu-San alleviates the imbalance of intestinal homeostasis in dextran sodium sulfate-induced colitis mice by regulating gut microbiota and inhibiting the NLRP3 inflammasome activation
Inflammatory bowel disease (IBD), which encompasses Crohn's disease and ulcerative colitis, is a chronic and relapsing inf...
Yuanzhi powder facilitated Aβ clearance in APP/PS1 mice: Target to the drainage of glymphatic system and meningeal lymphatic vessels
Yuanzhi powder facilitated Aβ clearance in APP/PS1 mice: Target to the drainage of glymphatic system and meningeal lymphatic vessels
Alzheimer's disease (AD), the most prominent form of dementia, has become a severe global public health concern among the ...
Qishen granule attenuates doxorubicin-induced cardiotoxicity by protecting mitochondrial function and reducing oxidative stress through regulation of Sirtuin3
Qishen granule attenuates doxorubicin-induced cardiotoxicity by protecting mitochondrial function and reducing oxidative stress through regulation of Sirtuin3
During the 1960s, doxorubicin (DOX) was discovered to be one of the most effective medications against cancer (Octavia et ...
Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease
Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease
Parkinson disease (PD) is the second most common neurodegenerative disease with fast-growing morbidity (Bloem et al., 2021...
Phytochemical composition, toxicological profiling and effect on pup birth weight of Corchorus olitorius leaf extract in rats: Implications for fetal macrosomia control
Phytochemical composition, toxicological profiling and effect on pup birth weight of Corchorus olitorius leaf extract in rats: Implications for fetal macrosomia control
Worldwide, significant progress has been made in the fight against maternal and fetal mortality; however, available data s...
Exploring the efficacy of various wheat bran extracts in promoting burn wound healing: A comparative analysis
Exploring the efficacy of various wheat bran extracts in promoting burn wound healing: A comparative analysis
Bran is the partly ground husk of wheat or any other grain. It is mainly formed of fibres that human digestive enzymes can...
Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region
Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region
Volume 319, Part 1, 30 January 2024, 117172Author links open overlay panel, , , , , , , AbstractEthnopharmacological relev...
Acute and 90-day toxicological safety assessment of Shang-Ke-Huang-Shui lotion in New Zealand White rabbits
Acute and 90-day toxicological safety assessment of Shang-Ke-Huang-Shui lotion in New Zealand White rabbits
Shang-Ke-Huang-Shui lotion (SKHS hereafter), an experiential formula based on the theory of traditional Chinese medicine a...
Evaluation of the toxicity of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb. in in vitro and in vivo models
Evaluation of the toxicity of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb. in in vitro and in vivo models
Safety assessment is the first step in developing a new medicine, regardless of its origin (Andrade et al., 2016). The con...
Isolation and characterization of bioactive components from hydroalcoholic extract of Cymbopogon jwarancusa (Jones) Schult. to evaluate its hepatoprotective activity
Isolation and characterization of bioactive components from hydroalcoholic extract of Cymbopogon jwarancusa (Jones) Schult. to evaluate its hepatoprotective activity
The liver is a power house which plays an important role in metabolism and excretion. It performs several functions, inclu...
Efficacy and mechanism study of Baichanting compound, a combination of Acanthopanax senticosus (Rupr. and Maxim.) Harms, Paeonia lactiflora Pall and Uncaria rhynchophylla (Miq.) Miq. ex Havil, on Parkinson's disease based on metagenomics and metabolomics
Efficacy and mechanism study of Baichanting compound, a combination of Acanthopanax senticosus (Rupr. and Maxim.) Harms, Paeonia lactiflora Pall and Uncaria rhynchophylla (Miq.) Miq. ex Havil, on Parkinson's disease based on metagenomics and metabolomics
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease worldwide (Huang et al., 2021), with the m...
Essential oil from Inula japonica Thunb. And its phenolic constituents ameliorate pulmonary injury and fibrosis in bleomycin-treated mice
Essential oil from Inula japonica Thunb. And its phenolic constituents ameliorate pulmonary injury and fibrosis in bleomycin-treated mice
Pulmonary injuries are a common pathological consequence of lung infection, hydrocarbon aspiration, smoke inhalation, or p...
Traditionally used anti-diabetic plants in Kathua district of Union Territory of Jammu and Kashmir, India
Traditionally used anti-diabetic plants in Kathua district of Union Territory of Jammu and Kashmir, India
Diabetes mellitus (DM) is multifactorial metabolic disarray with complex etiologies that have both chronic and acute conse...
Neuroprotective and anti-amnesic effects of Laurus Nobilis essential oil against scopolamine-induced memory deficits in mice brain
Neuroprotective and anti-amnesic effects of Laurus Nobilis essential oil against scopolamine-induced memory deficits in mice brain
Oxidative stress play a major role in the aging process and is considered among the most involved factor in the pathogenes...
Bombyx batryticatus extract activates coagulation factor Ⅻ to promote angiogenesis in rats with cerebral ischemia/reperfusion injury
Bombyx batryticatus extract activates coagulation factor Ⅻ to promote angiogenesis in rats with cerebral ischemia/reperfusion injury
Ischemic stroke (IS) is a highly prevalent and disabling disease, ranking among the top three diseases with the highest mo...
A network pharmacology integrated serum pharmacochemistry strategy for uncovering efficacy of YXC on hepatocellular carcinoma
A network pharmacology integrated serum pharmacochemistry strategy for uncovering efficacy of YXC on hepatocellular carcinoma
Ethnopharmacological relevanceThe YangzhengXiaoji capsule (YXC) has a wide range of applications as effective traditional ...
Distribution profiles of phenolic compounds in a cultivar of wampee (Clausena lansium (Lour.) Skeels) fruits and in vitro anti-inflammatory activity
Distribution profiles of phenolic compounds in a cultivar of wampee (Clausena lansium (Lour.) Skeels) fruits and in vitro anti-inflammatory activity
Wampee (Clausena lansium (Lour.) Skeels), a Rutaceae plant, is extensively farmed in southern China, especially Guangdong,...
Corydalis saxicola Bunting total alkaloids improve NAFLD by suppressing de novo lipogenesis through the AMPK-SREBP1 axis
Corydalis saxicola Bunting total alkaloids improve NAFLD by suppressing de novo lipogenesis through the AMPK-SREBP1 axis
NAFLD is a series of liver diseases mainly characterized by hepatic lipid accumulation and steatosis, including simple hep...
Anti-hypertension effect of Wuwei Jiangya decoction via ACE2/Ang1-7/MAS signaling pathway in SHR based on network degree-distribution analysis
Anti-hypertension effect of Wuwei Jiangya decoction via ACE2/Ang1-7/MAS signaling pathway in SHR based on network degree-distribution analysis
Hypertension, a prominent worldwide health problem, is characterized as an increase in blood pressure (≥140/≥90 mmHg) freq...
Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation
Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation
Post-traumatic stress disorder (PTSD) is an abnormal neuropsychiatric reaction to severe stressors, such as natural disast...
Development and validation of a simple and rapid UPLC-MS/MS method for loganin and its application in pharmacokinetic and tissue distribution studies
Development and validation of a simple and rapid UPLC-MS/MS method for loganin and its application in pharmacokinetic and tissue distribution studies
Cornus officinalis Sieb. et Zucc., also known as “Shanzhuyu”, is a medicinal and edible homolog in traditional Chinese med...
The anticonvulsant effect of saiga horn on febrile seizures by regulating brain serotonin content and inhibiting neuroinflammation
The anticonvulsant effect of saiga horn on febrile seizures by regulating brain serotonin content and inhibiting neuroinflammation
FS is a common convulsive disease in children. FS mainly occurs in children aged 5 months–60 months, and is a common type ...
The dual effects of Congea chinensis Moldenke on inhibiting tumor cell proliferation and delaying aging by activating TERT transcriptional activity
The dual effects of Congea chinensis Moldenke on inhibiting tumor cell proliferation and delaying aging by activating TERT transcriptional activity
KeywordsCongea chinensis MoldenkeCytotoxic antitumor activityApoptosisTERTData availabilityAll data generated or analyzed ...
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