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Serum lactate dehydrogenase as a prognostic marker for treatment response in IDH wild-type glioblastoma patients undergoing stupp protocol
Serum lactate dehydrogenase as a prognostic marker for treatment response in IDH wild-type glioblastoma patients undergoing stupp protocol
Elevated lactate dehydrogenase (LDH), a marker of tumor aggressiveness and metabolic alterations, may predict treatment re...
The 5-factor modified frailty index as a prognostic factor for stereotactic radiosurgery in meningioma management
The 5-factor modified frailty index as a prognostic factor for stereotactic radiosurgery in meningioma management
Meningiomas are the most frequent primary intracranial malignancy. While surgical resection can confer long term tumor con...
Innovations in intraoperative therapies in neurosurgical oncology: a narrative review
Innovations in intraoperative therapies in neurosurgical oncology: a narrative review
High-grade gliomas (HGG) represent the most aggressive primary brain tumors in adults, characterized by high recurrence ra...
Association between tumor location and toxicity outcomes after stereotactic radiosurgery for brain metastases
Association between tumor location and toxicity outcomes after stereotactic radiosurgery for brain metastases
Toxicities associated with stereotactic radiosurgery (SRS) are important when considering treatment and supportive managem...
The clinical impact of EGFR alterations in elderly glioblastoma patients: results from a real-life cohort
The clinical impact of EGFR alterations in elderly glioblastoma patients: results from a real-life cohort
The incidence of glioblastoma in the elderly population is increasing as the worldwide population ages. The differential a...
Glioblastoma cells alter brain endothelial cell homeostasis and tight junction protein expression in vitro
Glioblastoma cells alter brain endothelial cell homeostasis and tight junction protein expression in vitro
Glioblastoma (GBM) is an aggressive therapy-resistant brain tumour that may impacts the integrity of the blood–brain...
Outcomes of adjuvant radiation treatment following subtotal resection of world health organization grade II meningiomas
Outcomes of adjuvant radiation treatment following subtotal resection of world health organization grade II meningiomas
Existing literature on adjuvant radiation after subtotal resection (STR) of WHO II meningiomas is limited by heterogenous ...
CAR-engineered NK cells versus CAR T cells in treatment of glioblastoma; strength and flaws
CAR-engineered NK cells versus CAR T cells in treatment of glioblastoma; strength and flaws
Glioblastoma (GBM) is a highly aggressive primary brain tumor that carries a grim prognosis. Because of the dearth of trea...
Implications of molecular classifications in glioma surgery
Implications of molecular classifications in glioma surgery
The incorporation of molecular markers into neuro-oncology has transformed our understanding of adult diffuse gliomas. Whi...
Magnetic resonance imaging techniques for monitoring glioma response to chemoradiotherapy
Magnetic resonance imaging techniques for monitoring glioma response to chemoradiotherapy
Treatment response assessment for gliomas currently uses changes in tumour size as measured with T1- and T2-weighted MRI. ...
A case series and review of stereotactic body radiation therapy for contiguous multilevel spine metastases
A case series and review of stereotactic body radiation therapy for contiguous multilevel spine metastases
A majority of published series report on stereotactic body radiation therapy (SBRT) for 1–2 contiguous vertebral lev...
Epidemiology of glioblastoma in Pakistan: a secondary analysis of the Pakistan Brain Tumor Epidemiology Study (PBTES)
Epidemiology of glioblastoma in Pakistan: a secondary analysis of the Pakistan Brain Tumor Epidemiology Study (PBTES)
The incidence and outcomes of glioblastoma (GBM) patients in Pakistan remain unassessed owing to a lack of cancer registri...
The impact of adjuvant radiotherapy on overall survival in spinal low-grade gliomas: a propensity score-matched analysis
The impact of adjuvant radiotherapy on overall survival in spinal low-grade gliomas: a propensity score-matched analysis
Spinal low-grade gliomas (sLGGs) are a group of tumors that arise from glial cells in the spinal cord. Current evidence su...
Pulsed focused ultrasound alters the proteomic profile of the tumor microenvironment in a syngeneic mouse model of glioblastoma
Pulsed focused ultrasound alters the proteomic profile of the tumor microenvironment in a syngeneic mouse model of glioblastoma
Glioblastoma (GBM), a lethal primary adult malignancy, is difficult to treat because of the restrictive nature of the bloo...
Amino acid metabolism in glioma: in vivo MR-spectroscopic detection of alanine as a potential biomarker of poor survival in glioma patients
Amino acid metabolism in glioma: in vivo MR-spectroscopic detection of alanine as a potential biomarker of poor survival in glioma patients
Reprogramming of amino acid metabolism is relevant for initiating and fueling tumor formation and growth. Therefore, there...
Glioblastoma in the real-world setting: patterns of care and outcome in the Austrian population
Glioblastoma in the real-world setting: patterns of care and outcome in the Austrian population
We present results of a retrospective population-based investigation of patterns of care and outcome of glioblastoma patie...
Biological effective dose as a predictor of local tumor control in stereotactic radiosurgery treated parasellar meningioma patients
Biological effective dose as a predictor of local tumor control in stereotactic radiosurgery treated parasellar meningioma patients
The radio-surgical literature increasingly uses biological effective dose (BED) as a replacement for absorbed dose to anal...
Study of prediction model for high-grade meningioma using fractal geometry combined with radiological features
Study of prediction model for high-grade meningioma using fractal geometry combined with radiological features
To establish a prediction model combining fractal geometry and radiological features, which consider the complexity of tum...
The role of intervention timing and treatment modality in visual recovery following pituitary apoplexy: a systematic review and meta-analysis
The role of intervention timing and treatment modality in visual recovery following pituitary apoplexy: a systematic review and meta-analysis
Pituitary apoplexy has historically been considered an emergent condition that necessitates surgical intervention when the...
Molecular characterization of gliosarcoma reveals prognostic biomarkers and clinical parallels with glioblastoma
Molecular characterization of gliosarcoma reveals prognostic biomarkers and clinical parallels with glioblastoma
Gliosarcoma is a rare histopathological variant of glioblastoma, but it is unclear whether distinct clinical or molecular ...
Long-term trends of publications in journal of neuro-oncology: a bibliographic study of a core journal in the field of neuro-oncology
Long-term trends of publications in journal of neuro-oncology: a bibliographic study of a core journal in the field of neuro-oncology
The Journal of Neuro-Oncology (JNO), established in 1983, plays a key role in publishing research on brain and spinal cord...
Targeting the RAS/MAPK pathway in children with glioma
Targeting the RAS/MAPK pathway in children with glioma
Pediatric gliomas are the most common brain tumor in children, encompassing both low-grade glioma (pLGG) and high-grade gl...
Expression features of targets for anti-glioma CAR-T cell immunotherapy
Expression features of targets for anti-glioma CAR-T cell immunotherapy
To investigate the expression features of common anti-glioma CAR-T targets (B7H3, CSPG4, EGFRv III, HER2 and IL-13Ra2) in ...
Short-term sensorimotor training incorporating cognitive tasks for pediatric survivors of posterior fossa tumors: a pilot study
Short-term sensorimotor training incorporating cognitive tasks for pediatric survivors of posterior fossa tumors: a pilot study
Posterior fossa tumors account for half of all childhood brain tumors, prompting the search for effective and affordable i...
Pituitary neuroendocrine tumors treated with stereotactic radiosurgery
Pituitary neuroendocrine tumors treated with stereotactic radiosurgery
Pituitary neuroendocrine tumors (pitNETs) are benign tumors that may recur after surgical resection or persist following m...
Quality of life after stereotactic radiosurgery for brain metastasis: an assessment from a prospective national registry
Quality of life after stereotactic radiosurgery for brain metastasis: an assessment from a prospective national registry
Stereotactic radiosurgery (SRS) is frequently used in the management of brain metastasis patients. However, there is an ur...
Comparative analysis of hypofractionated short-course versus standard radiation therapy in elderly patients with glioblastoma: analysis of nationwide database
Comparative analysis of hypofractionated short-course versus standard radiation therapy in elderly patients with glioblastoma: analysis of nationwide database
Hypofractionated short-course radiation therapy (SCRT) is an alternative treatment option for elderly or frail patients wi...
A multi-center, clinical analysis of IDH-mutant gliomas, WHO Grade 4: implications for prognosis and clinical trial design
A multi-center, clinical analysis of IDH-mutant gliomas, WHO Grade 4: implications for prognosis and clinical trial design
Mutations in the Isocitrate Dehydrogenase (IDH) genes, IDH1 or IDH2, define a group of adult diffuse gliomas associated wi...
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2–3 gliomas
Brain volume loss after cranial irradiation: a controlled comparison study between photon vs proton radiotherapy for WHO grade 2–3 gliomas
Radiation therapy (RT) is an integral treatment component in patients with glioma but associated with neurotoxicity. Proto...
Therapeutic strategies for mobile spine chordoma: en bloc Versus intralesional surgery with adjuvant charged-particle therapy
Therapeutic strategies for mobile spine chordoma: en bloc Versus intralesional surgery with adjuvant charged-particle therapy
The aim of this retrospective study is to analyze the impact of en bloc resection with negative margins versus intralesion...
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