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The Role of Sleep in Cardiovascular Disease
The Role of Sleep in Cardiovascular Disease
Sleep is an important component of cardiovascular (CV) health. This review summarizes the complex relationship between sle...
Artificial Intelligence in Cardiovascular Disease Prevention: Is it Ready for Prime Time?
Artificial Intelligence in Cardiovascular Disease Prevention: Is it Ready for Prime Time?
This review evaluates how Artificial Intelligence (AI) enhances atherosclerotic cardiovascular disease (ASCVD) risk assess...
Comparative Analysis of Atherogenic Lipoproteins L5 and Lp(a) in Atherosclerotic Cardiovascular Disease
Comparative Analysis of Atherogenic Lipoproteins L5 and Lp(a) in Atherosclerotic Cardiovascular Disease
Low-density lipoprotein (LDL) poses a risk for atherosclerotic cardiovascular disease (ASCVD). As LDL comprises various su...
Noninvasive Atherosclerotic Phenotyping: The Next Frontier into Understanding the Pathobiology of Coronary Artery Disease
Noninvasive Atherosclerotic Phenotyping: The Next Frontier into Understanding the Pathobiology of Coronary Artery Disease
Despite recent advances, coronary artery disease remains one of the leading causes of mortality worldwide. Noninvasive ima...
The Effects of FABP4 on Cardiovascular Disease in the Aging Population
The Effects of FABP4 on Cardiovascular Disease in the Aging Population
Fatty acid-binding protein 4 (FABP4) plays a role in lipid metabolism and cardiovascular health. In this paper, we cover F...
Roles and Mechanisms of miRNAs in Abdominal Aortic Aneurysm: Signaling Pathways and Clinical Insights
Roles and Mechanisms of miRNAs in Abdominal Aortic Aneurysm: Signaling Pathways and Clinical Insights
Abdominal aortic aneurysm refers to a serious medical condition that can cause the irreversible expansion of the abdominal...
Pharmacotherapy for Coronary Artery Disease and Acute Coronary Syndrome in the Aging Population
Pharmacotherapy for Coronary Artery Disease and Acute Coronary Syndrome in the Aging Population
To provide a comprehensive summary of relevant studies and evidence concerning the utilization of different pharmacotherap...
Subclinical Atherosclerosis to Guide Treatment in Dyslipidemia and Diabetes Mellitus
Subclinical Atherosclerosis to Guide Treatment in Dyslipidemia and Diabetes Mellitus
Dyslipidemia and type 2 diabetes mellitus are two common conditions that are associated with an increased risk of atherosc...
Cardiovascular Health and Disease in the Pakistani American Population
Cardiovascular Health and Disease in the Pakistani American Population
This narrative review seeks to elucidate clinical and social factors influencing cardiovascular health, explore the challe...
What Causes Premature Coronary Artery Disease?
What Causes Premature Coronary Artery Disease?
This review provides an overview of genetic and non-genetic causes of premature coronary artery disease (pCAD). pCAD refer...
Gene Editing for the Treatment of Hypercholesterolemia
Gene Editing for the Treatment of Hypercholesterolemia
Here, we summarize the key findings from preclinical studies that tested the concept that editing of hepatic genes can low...
The Role of Genetics in Advancing Cardiometabolic Drug Development
The Role of Genetics in Advancing Cardiometabolic Drug Development
The objective of this review is to explore the role of genetics in cardiometabolic drug development. The declining costs o...
European Lipid Guidelines and Cardiovascular Risk Estimation: Current Status and Future Challenges
European Lipid Guidelines and Cardiovascular Risk Estimation: Current Status and Future Challenges
Genetic, experimental, epidemiologic, and clinical data support the causal role of elevated levels of low-density lipoprot...
Implications of Bias in Artificial Intelligence: Considerations for Cardiovascular Imaging
Implications of Bias in Artificial Intelligence: Considerations for Cardiovascular Imaging
Bias in artificial intelligence (AI) models can result in unintended consequences. In cardiovascular imaging, biased AI mo...
Novel Therapies for Lipoprotein(a): Update in Cardiovascular Risk Estimation and Treatment
Novel Therapies for Lipoprotein(a): Update in Cardiovascular Risk Estimation and Treatment
Lipoprotein(a) is an important causal risk factor for cardiovascular disease but currently no available medication effecti...
How Will Our Practice Change After the CLEAR Outcomes Trial?
How Will Our Practice Change After the CLEAR Outcomes Trial?
Bempedoic acid is a novel therapeutic agent that is designed to reduce levels of low-density lipoprotein cholesterol (LDL-...
Increased Cardiovascular Risk in Young Patients with CKD and the Role of Lipid-Lowering Therapy
Increased Cardiovascular Risk in Young Patients with CKD and the Role of Lipid-Lowering Therapy
Chronic kidney disease (CKD) is associated with a significantly increased risk of cardiovascular disease (CVD). This revie...
Lipoprotein(a): from Causality to Treatment
Lipoprotein(a): from Causality to Treatment
This paper reviews the evidence why lipoprotein(a) (Lp(a)) is a causal risk factor for cardiovascular disease and how high...
Targeting the Gut Microbiome to Treat Cardiometabolic Disease
Targeting the Gut Microbiome to Treat Cardiometabolic Disease
Cardiometabolic diseases, which include obesity, type 2 diabetes, and cardiovascular diseases, constitute a worldwide heal...
Whether and Why Do We Need a Vaccine Against Atherosclerosis? Can We Expect It Anytime Soon?
Whether and Why Do We Need a Vaccine Against Atherosclerosis? Can We Expect It Anytime Soon?
Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of premature death. Lipid disorders, particularly elevat...
Risk Stratification and Treatment of Obesity for Primary and Secondary Prevention of Cardiovascular Disease
Risk Stratification and Treatment of Obesity for Primary and Secondary Prevention of Cardiovascular Disease
In this review, we discuss contemporary and emerging approaches for risk stratification and management of excess adiposity...
Body Fat Depletion: the Yin Paradigm for Treating Type 2 Diabetes
Body Fat Depletion: the Yin Paradigm for Treating Type 2 Diabetes
To highlight that body fat depletion (the Yin paradigm) with glucose-lowering treatments (the Yang paradigm) are associate...
Obicetrapib: Reversing the Tide of CETP Inhibitor Disappointments
Obicetrapib: Reversing the Tide of CETP Inhibitor Disappointments
To discuss the history of cardiovascular outcomes trials of cholesteryl ester transfer protein (CETP) inhibitors and to de...
How to Handle Elevated Triglycerides: Life after PROMINENT
How to Handle Elevated Triglycerides: Life after PROMINENT
Hypertriglyceridaemia (HTG) is a common condition characterised by elevated levels of plasma triglycerides (TG), which are...
Eliminating Health Disparities in Atrial Fibrillation, Heart Failure, and Dyslipidemia: A Path Toward Achieving Pharmacoequity
Eliminating Health Disparities in Atrial Fibrillation, Heart Failure, and Dyslipidemia: A Path Toward Achieving Pharmacoequity
Pharmacoequity refers to the goal of ensuring that all patients have access to high-quality medications, regardless of the...
Machine Learning in Invasive and Noninvasive Coronary Angiography
Machine Learning in Invasive and Noninvasive Coronary Angiography
The objective of this review is to shed light on the transformative potential of machine learning (ML) in coronary angiogr...