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The TICE Pathway: Mechanisms and Potential Clinical Applications
The TICE Pathway: Mechanisms and Potential Clinical Applications
Transintestinal cholesterol excretion (TICE) is a non-biliary pathway that excretes excess cholesterol from the body throu...
Fixed Combination for the Treatment of Dyslipidaemia
Fixed Combination for the Treatment of Dyslipidaemia
It is clear from epidemiological studies that patients at high and very-high risk of atherosclerotic cardiovascular diseas...
Precision Nutrition and Cardiovascular Disease Risk Reduction: the Promise of High-Density Lipoproteins
Precision Nutrition and Cardiovascular Disease Risk Reduction: the Promise of High-Density Lipoproteins
Emerging evidence supports the promise of precision nutritional approaches for cardiovascular disease (CVD) prevention. He...
Promoting Cardiovascular Health in the Community: Training the Next Generation of Scientists in the Jackson Heart Study
Promoting Cardiovascular Health in the Community: Training the Next Generation of Scientists in the Jackson Heart Study
The aim of this article is to show the impact of the use of National Institutes of Health (NIH) research supplements in th...
Invasive Coronary Assessment in Myocardial Ischemia with No Obstructive Coronary Arteries
Invasive Coronary Assessment in Myocardial Ischemia with No Obstructive Coronary Arteries
The purpose of this review is threefold: (i) to give an overview of well-established invasive methods for assessing patien...
The Greatly Under-Represented Role of Smooth Muscle Cells in Atherosclerosis
The Greatly Under-Represented Role of Smooth Muscle Cells in Atherosclerosis
This article summarizes previous and recent research on the fundamental role of arterial smooth muscle cells (SMCs) as dri...
Treatment of Lp(a): Is It the Future or Are We Ready Today?
Treatment of Lp(a): Is It the Future or Are We Ready Today?
The goal of this review is to present the pharmacodynamic effectiveness as well as the clinical efficacy and safety of inv...
The Intersection Between COVID-19, Cardiovascular Disease, and Diet: a Review
The Intersection Between COVID-19, Cardiovascular Disease, and Diet: a Review
Cardiovascular disease (CVD) is one of the top comorbidities associated with COVID-19—both pre- and post-infection. ...
Updates in Drug Treatment of Severe Hypertriglyceridemia
Updates in Drug Treatment of Severe Hypertriglyceridemia
To provide an insight into the new pharmacological options for the treatment of severe hypertriglyceridemia (sHTG). sHTG i...
The Pandemic of Coronary Heart Disease in the Middle East and North Africa: What Clinicians Need to Know
The Pandemic of Coronary Heart Disease in the Middle East and North Africa: What Clinicians Need to Know
Coronary heart disease (CHD) is the leading cause of morbidity, mortality, and disability in the Middle East and North Afr...
Mechanosensing and Mechanosignal Transduction in Atherosclerosis
Mechanosensing and Mechanosignal Transduction in Atherosclerosis
This review aims to summarize the latest findings on mechanosensing in atherosclerosis, elucidating the molecular mechanis...
The Pandemic of Coronary Artery Disease in the Sub-Saharan Africa: What Clinicians Need to Know
The Pandemic of Coronary Artery Disease in the Sub-Saharan Africa: What Clinicians Need to Know
Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality globally with an accelerated increase in CVD...
Cholesterol Screening in Children: Is a Universal Approach Working?
Cholesterol Screening in Children: Is a Universal Approach Working?
Purpose of Review: Ample evidence supports that an individual’s lifetime risk of atherosclerotic cardiovascular dise...
Hypertension and Dyslipidemia: the Two Partners in Endothelium-Related Crime
Hypertension and Dyslipidemia: the Two Partners in Endothelium-Related Crime
The goal of this article is to characterize the endothelium’s role in the development of hypertension and dyslipidem...
Sport as Medicine for Dyslipidemia (and Other Risk Factors)
Sport as Medicine for Dyslipidemia (and Other Risk Factors)
Dyslipidemia is a common condition characterized by abnormal lipid levels in the blood, which can increase the risk of car...
Effects of Omega-3 Fatty Acids on Flow-mediated Dilatation and Carotid Intima Media Thickness: A Meta-analysis
Effects of Omega-3 Fatty Acids on Flow-mediated Dilatation and Carotid Intima Media Thickness: A Meta-analysis
To investigate the effects of omega-3 fatty acids on flow-mediated dilatation (FMD) and carotid intima-media thickness (CI...
The COVID-19 Pandemic and Coronary Heart Disease: the Next Surge
The COVID-19 Pandemic and Coronary Heart Disease: the Next Surge
In this narrative review, we highlight different ways in which the COVID-19 pandemic has impacted coronary heart disease (...
Algorithms for Treating Dyslipidemia in Youth
Algorithms for Treating Dyslipidemia in Youth
The goal of this article is to review algorithms for treating dyslipidemia in youth, discuss pitfalls, propose enhanced al...
Protective Effects of Different Classes, Intensity, Cumulative Dose-Dependent of Statins Against Primary Ischemic Stroke in Patients with Type 2 Diabetes Mellitus
Protective Effects of Different Classes, Intensity, Cumulative Dose-Dependent of Statins Against Primary Ischemic Stroke in Patients with Type 2 Diabetes Mellitus
The aim of this study is to investigate the protective effects of different statin classes, intensity, and cumulative dose...
Effects of the COVID-19 Pandemic on Pediatric and Adolescent ASCVD Risk Factors
Effects of the COVID-19 Pandemic on Pediatric and Adolescent ASCVD Risk Factors
In this review, we provide insight into and raise awareness of the impact of the COVID-19 pandemic on the prevalence of ac...
An Update on Nutrition Guidance for Cardiovascular Health
An Update on Nutrition Guidance for Cardiovascular Health
The goal of this article is to summarize recent guidance on diet and cardiovascular health. Cardiovascular diseases are th...
Community-Based Interventions to Address Disparities in Cardiometabolic Diseases Among Minoritized Racial and Ethnic Groups
Community-Based Interventions to Address Disparities in Cardiometabolic Diseases Among Minoritized Racial and Ethnic Groups
Cardiometabolic diseases (CMDs) are leading causes of death and disproportionally impact historically marginalized racial/...
Family Meals and Cardiometabolic Risk Factors in Young Children
Family Meals and Cardiometabolic Risk Factors in Young Children
Family meals represent a novel strategy for improving cardiovascular health in youth. The purpose of this paper is to desc...
Statin Intolerance: an Overview of US and International Guidance
Statin Intolerance: an Overview of US and International Guidance
To review recent international and domestic definitions, considerations, and treatment algorithms for statin intolerance, ...
Membrane Cholesterol Interactions with Proteins in Hypercholesterolemia-Induced Endothelial Dysfunction
Membrane Cholesterol Interactions with Proteins in Hypercholesterolemia-Induced Endothelial Dysfunction
The goal of this review is to highlight work identifying mechanisms driving hypercholesterolemia-mediated endothelial dysf...
Lipoprotein(a): a Case for Universal Screening in Youth
Lipoprotein(a): a Case for Universal Screening in Youth
Lipoprotein(a) has emerged as a strong independent risk factor for cardiovascular disease. Targeted screening recommendati...
T-cell Cholesterol Accumulation, Aging, and Atherosclerosis
T-cell Cholesterol Accumulation, Aging, and Atherosclerosis
The majority of leukocytes in advanced human atherosclerotic plaques are T-cells. T-cell subsets exert pro- or anti-athero...
Decreasing Sedentary Behaviors in Youth to Prevent and Manage Childhood Obesity: Is It Realistic?
Decreasing Sedentary Behaviors in Youth to Prevent and Manage Childhood Obesity: Is It Realistic?
Decreasing sedentary behaviors has been proposed as one approach to reduce the rate of obesity in youth. This review summa...
LDL Transcytosis by the Arterial Endothelium—Atherosclerosis by a Thousand Cuts?
LDL Transcytosis by the Arterial Endothelium—Atherosclerosis by a Thousand Cuts?
The accumulation of LDL in the arterial intima is an initiating event in atherosclerosis. After decades of controversy, it...
Utility of FFRCT in Patients with Chest Pain
Utility of FFRCT in Patients with Chest Pain
The goal of this article is to review the data supporting the use of fractional flow reserve derived from coronary compute...
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