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Advances and challenges in the treatment of myasthenia gravis
Advances and challenges in the treatment of myasthenia gravis
Myasthenia gravis (MG) is a chronic autoimmune disease with fluctuating muscle weakness and fatigability. Standard immunom...
Adverse events of rituximab in neuromyelitis optica spectrum disorder: a systematic review and meta-analysis
Adverse events of rituximab in neuromyelitis optica spectrum disorder: a systematic review and meta-analysis
Background:The adverse events (AEs) of rituximab (RTX) for neuromyelitis optica spectrum disorder (NMOSD) are incompletely...
Anti-GFAP-antibody positive postinfectious acute cerebellar ataxia and myoclonus after COVID-19: a case report
Anti-GFAP-antibody positive postinfectious acute cerebellar ataxia and myoclonus after COVID-19: a case report
We present a case of acute cerebellar ataxia and myoclonus with detected anti-GFAP-antibodies in a patient recently recove...
Subcutaneous cladribine to treat multiple sclerosis: experience in 208 patients
Subcutaneous cladribine to treat multiple sclerosis: experience in 208 patients
Objective:To report on safety and effectiveness of subcutaneous cladribine (Litak®) in multiple sclerosis (MS) patients.Me...
Radiomics-based prediction of hemorrhage expansion among patients with thrombolysis/thrombectomy related-hemorrhagic transformation using machine learning
Radiomics-based prediction of hemorrhage expansion among patients with thrombolysis/thrombectomy related-hemorrhagic transformation using machine learning
Introduction:Patients with hemorrhagic transformation (HT) were reported to have hemorrhage expansion. However, identifica...
Validation of a shortened FAST-ED algorithm for smartphone app guided stroke triage
Validation of a shortened FAST-ED algorithm for smartphone app guided stroke triage
Background and Purpose:Large vessel occlusion (LVO) recognition scales were developed to identify patients with LVO-relate...
Advances in dementia with Lewy bodies
Advances in dementia with Lewy bodies
Dementia with Lewy bodies (DLB) is a clinical diagnosis representing a specific presentation of a pathological α-synuclein...
The German Multiple Sclerosis and Pregnancy Registry: rationale, objective, design, and first results
The German Multiple Sclerosis and Pregnancy Registry: rationale, objective, design, and first results
Objectives:Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) predominantly affect women of repro...
Comment on: Clinico-radiologic features and therapeutic strategies in tumefactive demyelination: a retrospective analysis of 50 consecutive cases
Comment on: Clinico-radiologic features and therapeutic strategies in tumefactive demyelination: a retrospective analysis of 50 consecutive cases
1. Vakrakou, AG, Tzanetakos, D, Evangelopoulos, ME, et al. Clinico-radiologic features and therapeutic strategies in tumef...
FAST-ED scale smartphone app-based prediction of large vessel occlusion in suspected stroke by emergency medical service
FAST-ED scale smartphone app-based prediction of large vessel occlusion in suspected stroke by emergency medical service
Background and Purpose:Considering the highly time-dependent therapeutic effect of endovascular treatment in patients with...
A systematic review of relapse rates during pregnancy and postpartum in patients with relapsing multiple sclerosis
A systematic review of relapse rates during pregnancy and postpartum in patients with relapsing multiple sclerosis
Introduction:Pregnancy is widely accepted as a period when relapses of multiple sclerosis (MS) are decreased, with an incr...
Efficacy and safety of immunosuppressive therapy in myelin oligodendrocyte glycoprotein antibody–associated disease: a systematic review and meta-analysis
Efficacy and safety of immunosuppressive therapy in myelin oligodendrocyte glycoprotein antibody–associated disease: a systematic review and meta-analysis
Background:A considerable number of patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) ...
Surgical outcome and prognostic factors in spinal cord ependymoma: a single-center, long-term follow-up study
Surgical outcome and prognostic factors in spinal cord ependymoma: a single-center, long-term follow-up study
Objective:Spinal cord ependymomas account for 3–6% of all central nervous system tumors and around 60% of all intramedulla...
Longitudinal treatment responsiveness on plasma neurofilament light chain and glial fibrillary acidic protein levels in neuromyelitis optica spectrum disorder
Longitudinal treatment responsiveness on plasma neurofilament light chain and glial fibrillary acidic protein levels in neuromyelitis optica spectrum disorder
Background:Neurofilament light chain (NfL) and glial fibrilliary acidic protein (GFAP) have been suggested to be biomarker...
Corrigendum to “Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: interim analysis of post-marketing surveillance”
Corrigendum to “Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: interim analysis of post-marketing surveillance”
Access to society journal content varies across our titles. If you have access to a journal via a society or association ...
Association of serum neurofilament light chain levels and neuropsychiatric manifestations in systemic lupus erythematosus
Association of serum neurofilament light chain levels and neuropsychiatric manifestations in systemic lupus erythematosus
Background:The aim was to evaluate the diagnostic potential of serum neurofilament light chain (sNfL) measurements in pati...
Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage
Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage
Intracerebral hemorrhage (ICH) can be divided into a primary and secondary phase. In the primary phase, hematoma volume is...
Response to antiseizure medications in epileptic patients with malformation of cortical development
Response to antiseizure medications in epileptic patients with malformation of cortical development
Background:Malformation of cortical development (MCD) is one of the most common causes of pharmacoresistant epilepsy. Impr...
Cyclophosphamide in highly aggressive Marburg-like multiple sclerosis
Cyclophosphamide in highly aggressive Marburg-like multiple sclerosis
1. Vakrakou, AG, Tzanetakos, D, Evangelopoulos, ME, et al. Clinico-radiologic features and therapeutic strategies in tumef...
Treatment patterns in pediatric patients with multiple sclerosis in Germany—a nationwide claim-based analysis
Treatment patterns in pediatric patients with multiple sclerosis in Germany—a nationwide claim-based analysis
Background:The manifestation of multiple sclerosis (MS) in childhood and adolescence occurs in 3%−5% of all MS cases. Howe...
Predictors of adherence and persistence to disease-modifying therapies in Multiple Sclerosis
Predictors of adherence and persistence to disease-modifying therapies in Multiple Sclerosis
Background and Aims:In multiple sclerosis (MS), non-adherence/non-persistence is related to suboptimal response to treatme...
No evidence for loss of natalizumab effectiveness with every-6-week dosing: a propensity score–matched comparison with every-4-week dosing in patients enrolled in the Tysabri Observational Program (TOP)
No evidence for loss of natalizumab effectiveness with every-6-week dosing: a propensity score–matched comparison with every-4-week dosing in patients enrolled in the Tysabri Observational Program (TOP)
Background:Extended interval dosing of natalizumab is associated with significantly lower progressive multifocal leukoence...
Efficacy and tolerability of antiseizure drugs
Efficacy and tolerability of antiseizure drugs
Drug-resistant epilepsy occurs in 25–30% of patients. Furthermore, treatment with a first-generation antiseizure drug (ASD...
Glycemic variability of acute stroke patients and clinical outcomes: a continuous glucose monitoring study
Glycemic variability of acute stroke patients and clinical outcomes: a continuous glucose monitoring study
Introduction:Glycemic variability (GV) has been associated with worse prognosis in critically ill patients. We sought to e...
Erratum to “A propensity-matched comparison of long-term disability worsening in patients with multiple sclerosis treated with dimethyl fumarate or fingolimod”
Erratum to “A propensity-matched comparison of long-term disability worsening in patients with multiple sclerosis treated with dimethyl fumarate or fingolimod”
Access to society journal content varies across our titles. If you have access to a journal via a society or association ...
MRI as a first-line imaging modality in acute ischemic stroke: a sustainable concept
MRI as a first-line imaging modality in acute ischemic stroke: a sustainable concept
Background:Computed tomography (CT) scans are the first-line imaging technique in acute stroke patients based on the argum...
Non-invasive markers of liver fibrosis and outcome in large vessel occlusion stroke
Non-invasive markers of liver fibrosis and outcome in large vessel occlusion stroke
Background:Liver fibrosis has been identified as an outcome predictor in cardiovascular disease and has been associated wi...
Do somatosensory deficits predict efficacy of neurorehabilitation using neuromuscular electrical stimulation for moderate to severe motor paralysis of the upper limb in chronic stroke?
Do somatosensory deficits predict efficacy of neurorehabilitation using neuromuscular electrical stimulation for moderate to severe motor paralysis of the upper limb in chronic stroke?
Background:Various neurorehabilitation programs have been developed to promote recovery from motor impairment of upper ext...
Treatment approaches to patients with multiple sclerosis and coexisting autoimmune disorders
Treatment approaches to patients with multiple sclerosis and coexisting autoimmune disorders
The past decades have yielded major therapeutic advances in many autoimmune conditions – such as multiple sclerosis (MS) –...
A novel score for evaluating cerebral aneurysms treated with flow diversion: 4F-flow diversion predictive score
A novel score for evaluating cerebral aneurysms treated with flow diversion: 4F-flow diversion predictive score
Background and purpose:Although grading scales for angiography outcomes following cerebral aneurysm treatment with flow di...
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