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Editorial: Control of biofilms to control caries
Editorial: Control of biofilms to control caries
Dental caries, a disease caused by bacterial biofilms, is one of the most prevalent chronic diseases in humans worldwide. ...
The interplay between copper metabolism and microbes: in perspective of host copper-dependent ATPases ATP7A/B
The interplay between copper metabolism and microbes: in perspective of host copper-dependent ATPases ATP7A/B
Copper, a vital element in various physiological processes, is transported from the gastrointestinal tract to tissues and ...
Endobronchial optical coherence tomography helps to estimate the cartilage damage of the central airway in TBTB patients
Endobronchial optical coherence tomography helps to estimate the cartilage damage of the central airway in TBTB patients
PurposeAt present, there are few examination methods used to evaluate tracheobronchial cartilage damage. In our study, we ...
Factors affecting the early establishment of neonatal intestinal flora and its intervention measures
Factors affecting the early establishment of neonatal intestinal flora and its intervention measures
In recent years, it has become evident that early-life intestinal flora plays a pivotal role in determining human health. ...
Carbapenemase genes distribution in clonal lineages of Acinetobacter baumannii: a comprehensive study on plasmids and chromosomes
Carbapenemase genes distribution in clonal lineages of Acinetobacter baumannii: a comprehensive study on plasmids and chromosomes
BackgroundThe global spread of plasmids carrying carbapenemase genes within carbapenem resistant Acinetobacter baumannii (...
Molecular epidemiology and antimicrobial resistance patterns of carbapenem-resistant Acinetobacter baumannii isolates from patients admitted at ICUs of a teaching hospital in Zunyi, China
Molecular epidemiology and antimicrobial resistance patterns of carbapenem-resistant Acinetobacter baumannii isolates from patients admitted at ICUs of a teaching hospital in Zunyi, China
BackgroundCarbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a predominant strain of healthcare-associated...
Clinical characteristics and high risk factors of patients with Omicron variant strain infection in Hebei, China
Clinical characteristics and high risk factors of patients with Omicron variant strain infection in Hebei, China
ObjectiveThe Omicron variant has a weaker pathogenicity compared to the Delta variant but is highly transmissible and elde...
Corrigendum: Two small-molecule inhibitors of Toxoplasma gondii proliferation in vitro
Corrigendum: Two small-molecule inhibitors of Toxoplasma gondii proliferation in vitro
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Association between gut microbiota and NAFLD/NASH: a bidirectional two-sample Mendelian randomization study
Association between gut microbiota and NAFLD/NASH: a bidirectional two-sample Mendelian randomization study
BackgroundRecent studies have suggested a relationship between gut microbiota and non-alcoholic fatty liver disease (NAFLD...
ddPCR provides a sensitive test compared with GeneXpert MTB/RIF and mNGS for suspected Mycobacterium tuberculosis infection
ddPCR provides a sensitive test compared with GeneXpert MTB/RIF and mNGS for suspected Mycobacterium tuberculosis infection
IntroductionThe Metagenomics next-generation sequencing (mNGS) and GeneXpert MTB/RIF assay (Xpert) exhibited a sensitivity...
Mendelian randomization suggests a causal relationship between gut dysbiosis and thyroid cancer
Mendelian randomization suggests a causal relationship between gut dysbiosis and thyroid cancer
BackgroundAlterations in gut microbiota composition and function have been linked to the development and progression of th...
Performance of next-generation sequencing for diagnosis of blood infections by Klebsiella pneumoniae
Performance of next-generation sequencing for diagnosis of blood infections by Klebsiella pneumoniae
ObjectiveKlebsiella pneumoniae (Kp) bloodstream infections (BSI) can be a life-threatening opportunistic infection. We aim...
Virulence-related genotypic differences among Bacillus cereus ocular and gastrointestinal isolates and the relationship to endophthalmitis pathogenesis
Virulence-related genotypic differences among Bacillus cereus ocular and gastrointestinal isolates and the relationship to endophthalmitis pathogenesis
BackgroundBacillus cereus (Bc) can cause self-limiting gastrointestinal infections, but when infecting the eye, can cause ...
The pathogenic and clinical characteristics of severe fever with thrombocytopenia syndrome patients with co-infections
The pathogenic and clinical characteristics of severe fever with thrombocytopenia syndrome patients with co-infections
ObjectiveThe study aimed to comprehensively describe and evaluate the pathogenic and clinical characteristics of severe fe...
Exploring the antibacterial and dermatitis-mitigating properties of chicken egg white-synthesized zinc oxide nano whiskers
Exploring the antibacterial and dermatitis-mitigating properties of chicken egg white-synthesized zinc oxide nano whiskers
IntroductionZinc oxide nanoparticles (ZnO-NPs) have garnered considerable interest in biomedical research primarily owing ...
Editorial: Respiratory microbiome in health and disease
Editorial: Respiratory microbiome in health and disease
Respiratory diseases, such as COVID-19, pneumonia, asthma, chronic obstructive pulmonary disease, and lung cancer etc., ar...
Editorial: Roles of microbes in esophageal disease
Editorial: Roles of microbes in esophageal disease
The human body is home to a vast ecosystem of microorganisms, collectively known as the microbiome, which plays a pivotal ...
Clinical screening of Nocardia in sputum smears based on neural networks
Clinical screening of Nocardia in sputum smears based on neural networks
ObjectiveNocardia is clinically rare but highly pathogenic in clinical practice. Due to the lack of Nocardia screening met...
One-plasmid double-expression system for preparation of MS2 virus-like particles packaging SARS-CoV-2 RNA
One-plasmid double-expression system for preparation of MS2 virus-like particles packaging SARS-CoV-2 RNA
COVID-19 is a disease caused by a virus named SARS-CoV-2. SARS-CoV-2 is a single-stranded positive-sense RNA virus. Revers...
Clinical application of amplification-based versus amplification-free metagenomic next-generation sequencing test in infectious diseases
Clinical application of amplification-based versus amplification-free metagenomic next-generation sequencing test in infectious diseases
BackgroundRecently, metagenomic next-generation sequencing (mNGS) has been used in the diagnosis of infectious diseases (I...
Calprotectin blockade inhibits long-term vascular pathology following peritoneal dialysis-associated bacterial infection
Calprotectin blockade inhibits long-term vascular pathology following peritoneal dialysis-associated bacterial infection
Bacterial infections and the concurrent inflammation have been associated with increased long-term cardiovascular (CV) ris...
Carbon source–dependent capsule thickness regulation in Streptococcus pneumoniae
Carbon source–dependent capsule thickness regulation in Streptococcus pneumoniae
BackgroundThe polysaccharide capsule of Streptococcus pneumoniae plays a major role in virulence, adherence to epithelial ...
Antiviral options and therapeutics against influenza: history, latest developments and future prospects
Antiviral options and therapeutics against influenza: history, latest developments and future prospects
Drugs and chemotherapeutics have helped to manage devastating impacts of infectious diseases since the concept of ‘magic b...
Editorial: The interaction between viruses and the host immune system in persistent infection from a metabolic perspective
Editorial: The interaction between viruses and the host immune system in persistent infection from a metabolic perspective
In recent years, our understanding of viral infections and their intricate dance with the host immune system has evolved s...
Non-pathogenic Neisseria species of the oropharynx as a reservoir of antimicrobial resistance: a cross-sectional study
Non-pathogenic Neisseria species of the oropharynx as a reservoir of antimicrobial resistance: a cross-sectional study
Commensal Neisseria species of the oropharynx represent a significant reservoir of antimicrobial resistance determinants t...
Rapid detection of antimicrobial resistance in methicillin-resistant Staphylococcus aureus using MALDI-TOF mass spectrometry
Rapid detection of antimicrobial resistance in methicillin-resistant Staphylococcus aureus using MALDI-TOF mass spectrometry
Antimicrobial resistance is a growing problem in modern healthcare. Most antimicrobial susceptibility tests (AST) require ...
Multi-omics approaches reveal the molecular mechanisms underlying the interaction between Clonorchis sinensis and mouse liver
Multi-omics approaches reveal the molecular mechanisms underlying the interaction between Clonorchis sinensis and mouse liver
IntroductionClonorchiasis remains a serious global public health problem, causing various hepatobiliary diseases. However,...
Impact of actin polymerization and filopodia formation on herpes simplex virus entry in epithelial, neuronal, and T lymphocyte cells
Impact of actin polymerization and filopodia formation on herpes simplex virus entry in epithelial, neuronal, and T lymphocyte cells
Herpes simplex virus type 1 (HSV-1) has been known as a common viral pathogen that can infect several parts of the body, l...
Flying under the radar – impact and factors influencing asymptomatic DENV infections
Flying under the radar – impact and factors influencing asymptomatic DENV infections
The clinical outcome of DENV and other Flaviviruses infections represents a spectrum of severity that ranges from mild man...
A new double-antigen sandwich test based on the light-initiated chemiluminescent assay for detecting anti-hepatitis C virus antibodies with high sensitivity and specificity
A new double-antigen sandwich test based on the light-initiated chemiluminescent assay for detecting anti-hepatitis C virus antibodies with high sensitivity and specificity
ObjectivesThe aim of this study was to evaluate the performance of a new double-antigen sandwich test that is based on the...
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