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Specific cell subclusters of dental pulp stem cells respond to distinct pathogens through the ROS pathway
1 IntroductionMicrobial infections often cause organ dysfunctions and immune disorders threatening human health. Infectiou...
Effects of four potent entomopathogenic fungal isolates on the survival and performance of Telenomus remus, an egg parasitoid of fall armyworm
1 IntroductionFall armyworm (FAW), Spodoptera frugiperda J.E. Smith (Lepidoptera: Noctuidae) is a highly polyphagous pest ...
Comparing NGS-Based identification of bloodstream infections to traditional culture methods for enhanced ICU care: a comprehensive study
IntroductionBloodstream infections (BSIs) are a significant concern in intensive care unit (ICU) settings, contributing to...
Mechanism of emodin in treating hepatitis B virus-associated hepatocellular carcinoma: network pharmacology and cell experiments
1 IntroductionHepatocellular carcinoma (HCC) is a common malignant tumor with widespread global impact, particularly in de...
A causal association between esophageal cancer and the oral microbiome: a Mendelian randomization study based on an Asian population
IntroductionAccording to the global cancer statistics in 2020 conducted by Sung et al, esophageal cancer (EC) ranked 7th i...
First report of a blaNDM-producing extensively drug resistant Klebsiella pneumoniae ST437 in Italy
1 IntroductionCarbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) have spread rapidly around the world (Guo et ...
Effects of probiotic treatment on patients and animals with chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized control trials
1 IntroductionThe characteristics of chronic obstructive pulmonary disease (COPD) include persistent respiratory symptoms ...
Insights into the role of legionella effectors on host metabolic perturbations
IntroductionLegionella, a bacterium that commonly colonizes aquatic environments, has emerged as a significant public heal...
Editorial: Global excellence in fungal pathogenesis: Central and South America
Central and South America are regions with a high prevalence of significant fungal diseases such as paracoccidioidomycosis...
Genetic landscape of ESBL producing international clone ST410 of Escherichia coli from pediatric infections in Shenzhen, China
IntroductionThe emergence and widespread dissemination of extended-spectrum β-lactamases (ESBLs) in Escherichia coli (E. c...
Head-to-head comparison of two human papillomavirus vaccines for efficacy against cervical intraepithelial neoplasia grade 3 and adenocarcinoma in situ—population-based follow-up of two cluster-randomized trials
Human papillomavirus (HPV) vaccines protect against HPV-associated cancers. We report head-tohead comparison of the bivale...
Vaginal microbiota of pregnant women with Ureaplasma urealyticum and Mycoplasma hominis infections
1 IntroductionPreterm birth, defined as delivery before 37 weeks of gestation, poses a significant global public health is...
Recombinase-aided amplification assay for rapid detection of imipenem-resistant Pseudomonas aeruginosa and rifampin-resistant Pseudomonas aeruginosa
1 IntroductionPseudomonas aeruginosa, a prevalent opportunistic pathogen within the family Pseudomonadaceae, stands as a s...
Expression of goat poxvirus P32 protein and monoclonal antibody preparation
IntroductionGoat pox virus (GTPV) is a highly virulent infectious disease causing malignant pox (goat pox) in sheep and go...
Fine mapping-based multi-omics analysis interprets the gut-lung axis function of SGLT2 inhibitors
1 IntroductionPulmonary diseases are intricately linked to human life and lead to significant public health challenges on ...
Diagnostic performance of metagenomic sequencing in patients with suspected infection: a large-scale retrospective study
1 IntroductionWith over 8 million deaths worldwide, infectious diseases (IDs) remain the leading cause of morbidity and mo...
Combining network pharmacology, machine learning, molecular docking and molecular dynamic to explore the mechanism of Chufeng Qingpi decoction in treating schistosomiasis
1 IntroductionSchistosomiasis, a prevalent tropical parasitic infection, is predominantly attributed to the blood-dwelling...
Complement C3 deposition restricts the proliferation of internalized Staphylococcus aureus by promoting autophagy
1 IntroductionThe complement system is an indispensable component of the immune system. It contributes to the recognition ...
Autophagy: the misty lands of Chlamydia trachomatis infection
1 IntroductionChlamydia are Gram-negative, obligate intracellular bacterial pathogens and symbionts that inhabit a wide ra...
Human breast milk isolated lactic acid bacteria: antimicrobial and immunomodulatory activity on the Galleria mellonella burn wound model
Graphical Abstract. 1 IntroductionBurn wounds represent a critical challenge in healthcare due to their potential to co...
Streptococcus agalactiae isolated from clinical mastitis cases on large dairy farms in north China: phenotype, genotype of antimicrobial resistance and virulence genes
IntroductionBovine mastitis is one of the costliest diseases in the dairy industry due to the discarding of milk, costs of...
Global research trends on the links between gut microbiota and radiotherapy: a bibliometric analysis (2004-2023)
1 IntroductionIn recent decades, gut microbiota, a key regulator of host metabolism and immunity, has gained attention for...
Intervention in gut microbiota increases intestinal γ-aminobutyric acid and alleviates anxiety behavior: a possible mechanism via the action on intestinal epithelial cells
1 IntroductionNumerous commensal bacteria inhabit the intestinal lumen, forming the gut microbiota, and exert various phys...
Proteomics of severe SARS-COV-2 infection and paraquat poisoning in human lung tissue samples: comparison of microbial infected and toxic pulmonary fibrosis
Graphical Abstract. This study illuminates distinct protein-level differences by investigating pulmonary fibrosis pathw...
Targeting lon protease to inhibit persister cell formation in Salmonella Typhimurium: a drug repositioning approach
IntroductionBacterial pathogens have developed mechanisms to evade antibiotic treatment, resulting in treatment failures a...
Changes in the epidemiological patterns of respiratory syncytial virus and human metapneumovirus infection among pediatric patients and their correlation with severe cases: a long-term retrospective study
IntroductionPneumoviridae comprises large enveloped negative-sense RNA viruses, which was formerly a subfamily within the ...
The influence of Helicobacter pylori infection on acute coronary syndrome and lipid metabolism in the Chinese ethnicity
1 IntroductionHelicobacter pylori (H. pylori) has a wide range of adaptation mechanisms that enable its survival in the ac...
Distinctive features and prognostic utility of neutrophil in severe patients with Klebsiella pneumoniae infection
1 IntroductionKlebsiella pneumoniae is a prevalent Gram-negative bacterium known for its ability to cause various infectio...
Optimization of bacteriophage therapy for difficult-to-treat musculoskeletal infections: a bench-to-bedside perspective
1 IntroductionThe history of treating musculoskeletal infections (MSIs) with bacteriophages stretches back over 100 years....
Integrative study of chicken lung transcriptome to understand the host immune response during Newcastle disease virus challenge
IntroductionNewcastle disease is one of the significant issues in the poultry industry, having catastrophic effects worldw...
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