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Prediction of Golgi Polarity in Collectively Migrating Epithelial Cells Using Graph Neural Network
Prediction of Golgi Polarity in Collectively Migrating Epithelial Cells Using Graph Neural Network
In the stationary epithelium, the Golgi apparatus assumes an apical position, above the cell nucleus. However, during woun...
Protocol-dependent morphological changes in human embryonic stem cell aggregates during differentiation towards early pancreatic fate
Protocol-dependent morphological changes in human embryonic stem cell aggregates during differentiation towards early pancreatic fate
Cell therapy is one of the promising approaches used against type1 diabetes. Efficient generation of Human embryonic stem ...
On the variability in cell and nucleus shape
On the variability in cell and nucleus shape
Cell morphology is an important regulator of cell function. Many abnormalities in cellular behavior can be discerned from ...
MicroRNA-133a-3p inhibits lung adenocarcinoma development and cisplatin resistance through targeting GINS4
MicroRNA-133a-3p inhibits lung adenocarcinoma development and cisplatin resistance through targeting GINS4
GINS subunit complex 4 (GINS4) is fundamental to DNA replication and G1/S phase transition of the cell cycle in eukaryotes...
Umbilical cord blood cell clearance post-infusion in immune competent children with cerebral palsy
Umbilical cord blood cell clearance post-infusion in immune competent children with cerebral palsy
Umbilical cord blood cells have therapeutic potential for neurological disorders, through a paracrine mechanism of action....
Organoids in the clinic: a systematic review of outcomes
Organoids in the clinic: a systematic review of outcomes
Research on organoids has undergone significant advances during the last decade. However, outcomes from the use of organoi...
Altered expression of pulmonary epithelial cell markers in fetal and adult mice generated by in vitro embryo culture and embryo transfer
Altered expression of pulmonary epithelial cell markers in fetal and adult mice generated by in vitro embryo culture and embryo transfer
Lung development is impaired in mice generated through transfer of in vitro-derived blastocysts. The main objective of the...
Artificial microvesicles: new perspective on healing tendon wounds
Artificial microvesicles: new perspective on healing tendon wounds
Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presen...
Molecular characterization and differentiation of mesenchymal progenitor cells from human rheumatoid arthritis cartilage
Molecular characterization and differentiation of mesenchymal progenitor cells from human rheumatoid arthritis cartilage
The presence of mesenchymal progenitor cells (MPCs) in rheumatoid arthritis (RA) articular cartilage is sparsely investiga...
A Multistep Tumor Growth Model of High Grade Serous Ovarian Carcinoma Identifies Hypoxia Associated Signatures
A Multistep Tumor Growth Model of High Grade Serous Ovarian Carcinoma Identifies Hypoxia Associated Signatures
High-grade serous ovarian carcinoma (HGSC) is associated with late-stage disease presentation and poor prognosis, with lim...
Effect of Cell Derived Matrices on growth and differentiation of human Wharton’s jelly derived Mesenchymal Stem Cells
Effect of Cell Derived Matrices on growth and differentiation of human Wharton’s jelly derived Mesenchymal Stem Cells
Cell derived matrices (CDMs) are scaffolds constructed by decellularization of cellular matrices from different tissues an...
Aneuploidy rate and Stemness in Low-level Mosaic Human Embryonic Stem Cells in the Presence/Absence of Bortezomib, Paclitaxel and Lapatinib
Aneuploidy rate and Stemness in Low-level Mosaic Human Embryonic Stem Cells in the Presence/Absence of Bortezomib, Paclitaxel and Lapatinib
Human embryonic stem cells (hESCs) are predisposed to aneuploidy through continual passages. Some reports indicate more se...
Strategies and challenges in the treatment of dental enamel
Strategies and challenges in the treatment of dental enamel
Enamel tissue, the hardest body tissue, which covers the outside of the tooth shields the living tissue, but it erodes and...
miR-107 attenuates sepsis-induced myocardial injury by targeting PTEN and activating the PI3K/AKT signaling pathway
miR-107 attenuates sepsis-induced myocardial injury by targeting PTEN and activating the PI3K/AKT signaling pathway
Sepsis is a public health problem worldwide. This study investigated the mechanism of miR-107 on sepsis-induced myocardial...
miR-181a-5p restrains non-small cell lung cancer cell invasion and migration by regulating the GTSE1/p53/NF-κB axis
miR-181a-5p restrains non-small cell lung cancer cell invasion and migration by regulating the GTSE1/p53/NF-κB axis
microRNAs (miRNAs) are relevant to metastasis and invasion of non-small cell lung cancer (NSCLC). This study investigated ...
Influence of wound fluid on the transdifferentiation of human mesenchymal bone marrow stem cells into cancer-associated fibroblasts
Influence of wound fluid on the transdifferentiation of human mesenchymal bone marrow stem cells into cancer-associated fibroblasts
Cancer-associated fibroblasts (CAF) in the tumor microenvironment have a decisive influence on tumor growth and metastatic...
Cadherin-11 and its role in tissue fibrosis
Cadherin-11 and its role in tissue fibrosis
Fibrosis is the excessive deposition of extracellular matrix that results from chronic inflammation and injury, leading th...
Ionic detergent under pressure-vacuum as an innovative strategy to generate canine tracheal scaffold for organ engineering
Ionic detergent under pressure-vacuum as an innovative strategy to generate canine tracheal scaffold for organ engineering
Decellularized scaffolds applied in tissue engineering offer improvements, supplying the elevated necessity for organs and...
Acute Response of Engineered Cardiac Tissue to Pressure and Stretch
Acute Response of Engineered Cardiac Tissue to Pressure and Stretch
The heart is a dynamic organ, and the cardiac tissue experiences changes in pressure and stretch during the cardiac cycle....
Improving fat transplantation survival and vascularization with adenovirus E4+ endothelial cell-assisted lipotransfer
Improving fat transplantation survival and vascularization with adenovirus E4+ endothelial cell-assisted lipotransfer
Autologous fat transplantation is plagued by an unpredictable and often significant degree of graft loss. AdE4+ endothelia...
Insulin-like growth factor-1 promotes human uterine leiomyoma cells proliferation via PI3K/AKT/mTOR pathway
Insulin-like growth factor-1 promotes human uterine leiomyoma cells proliferation via PI3K/AKT/mTOR pathway
The present research aims to evaluate the expression of insulin-like growth factor-1 (IGF-1) in uterine leiomyoma, and exp...
Complex Material Properties of Gel-Amin: A Transparent and Ionically Conductive Hydrogel for Neural Tissue Engineering
Complex Material Properties of Gel-Amin: A Transparent and Ionically Conductive Hydrogel for Neural Tissue Engineering
The field of tissue engineering has benefited greatly from the broad development of natural and synthetic polymers. Extens...
Pentraxin-3 promotes LPS-induced pyroptosis in human periodontal ligament stem cells
Pentraxin-3 promotes LPS-induced pyroptosis in human periodontal ligament stem cells
The aim of this study was to explore the function of Pentraxin-3 (PTX3) in cell viability, pyroptosis, inflammation, osteo...
miR-654-5p suppresses migration and proliferation of vascular smooth muscle cells by targeting ADAMTS-7
miR-654-5p suppresses migration and proliferation of vascular smooth muscle cells by targeting ADAMTS-7
Coronary artery disease (CAD) is the first leading cause of death worldwide. Therefore, novel therapeutic strategies need ...
Development of a high-color flow cytometry panel for immunologic analysis of tissue injury and reconstruction in a rat model
Development of a high-color flow cytometry panel for immunologic analysis of tissue injury and reconstruction in a rat model
The rat model is an important resource in biomedical research due to its similarities to the human immune system and its u...
Static magnetic field promotes proliferation, migration, differentiation, and AKT activation of periodontal ligament stem cells
Static magnetic field promotes proliferation, migration, differentiation, and AKT activation of periodontal ligament stem cells
Periodontal ligament stem cells (PDLSCs) possess self-renewal and multilineage differentiation potential and exhibit great...
Effects of Pulsatility on Arterial Endothelial and Smooth Muscle cells
Effects of Pulsatility on Arterial Endothelial and Smooth Muscle cells
Continuous Flow Ventricular Assist Device (CFVAD) support in advanced heart failure patients causes diminished pulsatility...
Synthetic Small Molecules Induce Insulin Secretion and Pancreatic Beta-Cell-Specific Gene Expression
Synthetic Small Molecules Induce Insulin Secretion and Pancreatic Beta-Cell-Specific Gene Expression
Despite various efficient pharmaceuticals which are already used to manage diabetes, new drugs are needed to preserve and ...