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Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Deciphering the connectome, the ensemble of synaptic connections that underlie brain function, is a central goal of neuros...
Heat acclimation induces hypothalamic temperature sensitivity that promotes heat tolerance
Heat acclimation induces hypothalamic temperature sensitivity that promotes heat tolerance
After long-term heat exposure, a discrete group of hypothalamic neurons in the anterior ventromedial preoptic area become ...
A single-cell mass cytometry-based atlas of the developing mouse brain
A single-cell mass cytometry-based atlas of the developing mouse brain
Development of the mammalian brain requires precise molecular changes across diverse cell lineages. While single-cell RNA ...
Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Helmholtz Pioneer Campus, Helmholtz Zentrum München, Neuherberg, GermanyBoyan BonevPhysiological Genomics, Biomedical Cent...
MeCP2 goes into unmethylated territories
MeCP2 goes into unmethylated territories
Methyl-CpG-binding protein 2 (MeCP2) is a chromatin regulator whose loss of function causes Rett syndrome. It has been unc...
Microglia as hunters or gatherers of brain synapses
Microglia as hunters or gatherers of brain synapses
Over a decade ago, it was discovered that microglia, the brain’s immune cells, engulf synaptic material in a process...
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates
Duplication of methyl-CpG-binding protein 2 (MECP2) gene causes MECP2 duplication syndrome (MDS). To normalize the duplica...
Author Correction: Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain
F.M. Kirby Neurobiology Center, Boston Children’s Hospital, Boston, MA, USASamuel E. Marsh, Alec J. Walker, Lasse Dissing-...
Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation
Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation
Cooperative interactions profoundly shape individual and collective behaviors of social animals. Successful cooperation re...
Amygdala intercalated cells form an evolutionarily conserved system orchestrating brain networks
Amygdala intercalated cells form an evolutionarily conserved system orchestrating brain networks
The amygdala attributes valence and emotional salience to environmental stimuli and regulates how these stimuli affect beh...
Motivating interest in D3 dopamine receptors
Motivating interest in D3 dopamine receptors
Reward signaling via dopamine is most commonly thought of as acting through neurons expressing either D1 or D2 dopamine re...
Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance
Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance
Heat acclimation is an adaptive process that improves physiological performance and supports survival in the face of incre...
Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors
Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors
Dopamine (DA) release in striatal circuits, including the nucleus accumbens medial shell (mNAcSh), tracks separable featur...
Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells
Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells
Brain function relies on the generation of a large variety of morphologically and functionally diverse, but specific, neur...
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Department of Economics, Vrije Universiteit Amsterdam, Amsterdam, the NetherlandsRichard Karlsson Linnér, Ronald de Vlamin...
Focus on single-cell genomics
Single-cell genomics is deepening our understanding of the nervous system and shedding light on the heterogeneity of its c...
Author Correction: Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
These authors contributed equally: Carina Seah, Michael S. Breen, Tom Rusielewicz, Heather N. Bader.Pamela Sklar Division ...
Formation of long-term memory without short-term memory revealed by CaMKII inhibition
Formation of long-term memory without short-term memory revealed by CaMKII inhibition
Long-term memory (LTM) consolidation is thought to require the prior establishment of short-term memory (STM). Here we sho...
Multiple loci for foveolar vision in macaque monkey visual cortex
Multiple loci for foveolar vision in macaque monkey visual cortex
In humans and nonhuman primates, the central 1° of vision is processed by the foveola, a retinal structure that compr...
Meningeal immune cells influence early inhibition
Immune cells that originate in the meninges have an increasingly appreciated role in brain development and homeostasis. Mo...
Enteric neurons and gut immunity
Serotonin is primarily known for its roles in the CNS, but it is also produced by Tph2-expressing enteric neurons. A study...
Aversion crosses over
Amygdalo–striatal neurons have been implicated in the processing of appetitive and aversive valence. Adding to our underst...
Simultaneous representations of the past and future
A successful chess player uses knowledge of past strategies and games to anticipate their opponent’s moves, adapting their...
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Over the past decade, single-cell genomics technologies have allowed scalable profiling of cell-type-specific features, wh...
Membrane mechanics dictate axonal pearls-on-a-string morphology and function
Membrane mechanics dictate axonal pearls-on-a-string morphology and function
Axons are ultrathin membrane cables that are specialized for the conduction of action potentials. Although their diameter ...
Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle
Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle
The noradrenergic locus coeruleus (LC) regulates arousal levels during wakefulness, but its role in sleep remains unclear....
Wiring of a low-dimensional integrator network
Wiring of a low-dimensional integrator network
Vishwanathan and colleagues have reconstructed the wiring diagram of a brainstem circuit that controls gaze in zebrafish. ...
Klaus A. Miczek (1945–2024)
Klaus A. Miczek (1945–2024)
Klaus Miczek was born in Germany and earned his BA degree at the Padagogische Hochschule-Berlin in 19...
Autism spectrum disorder variation as a computational trade-off via dynamic range of neuronal population responses
Autism spectrum disorder variation as a computational trade-off via dynamic range of neuronal population responses
Individuals diagnosed with autism spectrum disorder (ASD) show neural and behavioral characteristics differing from the ne...
Converging cortical axes
Converging cortical axes
The cerebral cortex shows complex organization across diverse biological scales, from regional chemical and cellular speci...
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