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Antioxidant effects and protective potential of fruit extracts of Detarium microcarpum against arsenic trioxide-induced human lymphocytes DNA oxidative damages
Objective: The integrity of the DNA is continously menaced by the harmful genotoxic compounds. The endogenous system respo...
Anti-oxidant and anti-apoptotic effects of gamma-oryzanol on male reproductive function in chronic restraint stress in rats
Objective: This study investigates the effects of GO on depressive behaviors and reproductive parameters in rats exposed t...
Evaluating the effect of crocin on contrast-induced nephropathy in rats
Objective: Contrast-induced nephropathy (CIN) raises the risk of renal injury, but crocin, a saffron component, may improv...
Regulation of the microRNA profiles related to Myh7 and Myh6 in myocardial ischemia through proanthocyanidins and different intensity exercise training
Objective: Myocardial ischemia (MI) and circulatory arrest are associated with unfavorable cardiovascular outcomes. This s...
Effect of lupeol on testicular lesions induced by cadmium chloride in rats
Objective: Heavy metals and environmental pollutants, such as cadmium chloride, congenital disorders, and certain diseases...
Anti-cancer effects of frankincense methanolic extract on brain metastatic breast cancer cells
Objective: Brain metastasis in patients with breast cancer is considered a deadly event. The oleogum resins of Boswellia s...
The protective properties of resveratrol against glycerol-induced acute kidney injury in rats
Objective: After rhabdomyolysis, muscle tissue releases substances such as myoglobin, creatine kinase, and electrolytes in...
Apoptotic and anti-migratory activity of Citrus limon rind essential oil encapsulated in niosome against human breast cancer cells
Objective: This study aimed to formulate Citrus limon fruit rind’s essential oil (EO) and to analyze its impact on breast ...
The adjuvant therapy of edible herbal product including colchicum bulb, olive leaf, black cumin seeds, lavender flower, and ginger rhizome on the outcome of patients with severe and critical COVID-19: A double-blind randomized controlled clinical trial
Objective: The present study aimed at evaluating the effect of combination of medicinal plants, including Colchicum autumn...
The protective effects of Allium ampeloprasum Subsp Iranicum on cyclophosphamide-induced immunosuppression in NMRI Mice: A promising natural immunomodulator
Objective: Cyclophosphamide (CTX) is an effective anticancer drug, but toxic effects against normal human tissues are its ...
Fertility-enhancing effects of Prunus amygdalas oil on reproductive functions of male rats: A two-generation study
Objective: Prunus amygdalas (Almond; PA) has extensively been used in traditional medicine and has been the source of robu...
Examining efficacy and safety of ethyl acetate extract from Allium hirtifolium as complementary therapy in COVID-19: A randomized, multicenter, controlled clinical trial
Objective: Given the apparent life-threatening nature of COVID-19, finding an effective treatment is under investigation. ...
Perillyl alcohol, quercetin, and berberine combination therapy ameliorates experimental pulmonary arterial hypertension: Effects on the lung miR-204 expression, remodeling, and inflammatory factors
Objective: Pulmonary artery hypertension (PAH) is a devastating syndrome. Our previous studies showed that perillyl alcoho...
Investigating the effect of zeaxanthin on olanzapine-induced metabolic disorders in rats
Objective: Olanzapine (OLZ) is used by some patients with bipolar disorder and schizophrenia. Some of its side effects inc...
Melissa officinalis extract improved high-fat-diet-induced anxiety-like behaviors, depression, and memory impairment by regulation of serum BDNF levels in rats
Objective: Melissa officinalis (MO) hydroalcoholic extract has shown neuroprotective effects. We assess the possible thera...
Heracleum persicum L. extract protects gentamicin-induced testicular toxicity
Objective: The objective of this study was to assess the protective effects of Heracleum persicum L. leaves extract (HPE) ...
The effect of evening primrose oil on adolescent girl patients with PCOS: A double-blind placebo-controlled randomized study
Objective: Polycystic ovary syndrome (PCOS) is a common disorder among women of reproductive age. The goal of the current ...
Antimicrobial effectiveness of aqueous and alcoholic herbal extracts on Streptococcus mutans: A systematic review and meta-analysis of randomized controlled trials
Objective: Debates about the efficacy of herbal products in oral care have inspired researchers to conduct a large number ...
Preparation and evaluation of hair growth promoting effect of transferosomes containing red clover extract and caffeine alone or in combination
Objective: Trifolium pratense L. (Red clover) belongs to the Leguminosae family. This study was designed to develop transf...
Topical application of medicinal plant oils in pediatric-related disorders: A comparative review article based on traditional Persian medicine
Objective: Researchers have considered medicinal oils to prevent and treat pediatric diseases. In the traditional Persian ...
Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke
Objective: Brain ischemia generally results in irreversible brain damage or death. One of the most important features of a...
The preventive effects of Zataria multiflora and carvacrol and their co-administration with pioglitazolne on systemic inflammation and oxidative stress induced by paraquat inhalation in rats
Objective: The present study aimed to assess the impact of the aqueous-ethanolic extract of Zataria multiflora (ZM), carva...
Virtual screening of natural products as potential inhibitors of SARS-CoV-2 main protease, RNA-dependent RNA polymerase (RdRp) and Spike Protein: Database design, molecular docking and molecular dynamic study
Objective: COVID-19 is caused by the SARS-CoV-2 virus. In this study, around 300 herbal compounds were screened virtually ...
Protective effects of a mixture of multi-strain native Iranian probiotics on lead acetate-induced toxicity in the kidney of male rats: An integrated biochemical, molecular and histopathological study
Objective: In this study, the protective effects of native Iranian probiotics (Lactobacillus rhamnosus, Lactobacillus case...
Evaluation of the effect of Foeniculum vulgare fruit and Echium amoenum flower combination on the severity of physical and psychological symptoms of premenstrual syndrome
Objective: Echium amoenum (EA) and Foeniculum vulgare (FV) might be beneficial for the management of Premenstrual syndrome...
Effect of pretreatment with Devil's Claw on locomotor activity, infarct volume, and neuronal density in focal cerebral ischemia in rats
 Objective: Stroke is a highly prevalent and devastating conditionaffecting millions worldwide. The Devil's Claw (DCW...
Comparison of effects of P-coumaric acid and coumarin on colorectal cancer cell line by inducing apoptosis and autophagy
 Objective: Autophagy, as a cellular pathway involved inremoving damaged proteins and organelles, performs a vitalfunction...
The cardioprotective properties of Persicaria maculosa and Citrus sinensis extracts against doxorubicin-induced cardiotoxicity in mice
 Objective: This study assessed the cardioprotective properties ofPersicaria maculosa (PME) and Citrus sinensis (CME) hydr...
Medicinal plants used in traditional medicine to enhance immunity: A survey in the southeastern area of Morocco and a literature review
Objective: The threat of immune escape and the discovery of antibiotic-resistant pathogens, as well as the failure of cert...
Evaluating the efficacy of Terminalia chebula Retz. 5% cream compared to hydroquinone 2% cream in the treatment of melasma
Objective: Melasma is a multifactorial, chronic, acquired skin disorder of hyperpigmentation. Terminalia chebula Retz. (T....
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