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Staphylococcus aureus bacteraemia treatment outcomes in patients receiving ticagrelor vs a propensity-matched cohort receiving clopidogrel
To develop a taxonomy of interventions aimed at reducing emergency department (ED) transfers and/or hospitalizations from ...
In-vitro activity of ceftolozane/tazobactam against Pseudomonas aeruginosa collected in the Study for Monitoring Antimicrobial Resistance Trends (SMART) between 2016 and 2019 in China
Pseudomonas aeruginosa is a non-fermenting Gram-negative bacterium that can cause infections in humans, particularly indiv...
National surveillance of antimicrobial susceptibilities to ceftaroline, dalbavancin, telavancin, tedizolid, eravacycline, omadacycline, and other comparator antibiotics, and genetic characteristics of bacteremic Staphylococcus aureus isolates in adults: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) program in 2020
Methicillin-resistant Staphylococcus aureus (MRSA) was first described in the 1960s, with an increased prevalence of hospi...
REDS study: Retrospective effectiveness study of dalbavancin and other standard of care of the same IV antibiotic class in patients with ABSSSI
ObjectivesAcute bacterial skin and skin-structure infections (ABSSSIs) are a common source of morbidity in both the commun...
Pharmacokinetics/pharmacodynamics of ceftobiprole in patients on extracorporeal membrane oxygenation
With the increased use of extracorporeal membrane oxygenation (ECMO) to rescue patients with refractory acute respiratory ...
Comparative activity of newer β-lactam/β-lactamase inhibitor combinations against Pseudomonas aeruginosa isolates from US medical centres (2020–2021)
Volume 61, Issue 4, April 2023, 106744Author links open overlay panel, , , , , Highlights•3184 isolates were tested agains...
Outcomes associated with empiric cefepime for bloodstream infections caused by ceftriaxone-resistant, cefepime-susceptible Escherichia coli and Klebsiella pneumoniae
Extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) are becoming alarmingly prevalent and difficult to ma...
In-vitro antibacterial activity of omeprazole and esomeprazole in combination with ciprofloxacin as an alternative to repositioning against ESKAPE pathogens and evaluation of the cleavage capacity of plasmid DNA
Multidrug-resistant (MDR) Pseudomonas aeruginosa infections compromise both empirical and definitive antimicrobial therapi...
Outcomes of Daptomycin Plus Ceftaroline Versus Alternative Therapy for Persistent Methicillin-resistant Staphylococcus aureus (MRSA) Bacteraemia
Methicillin-resistant Staphylococcus aureus bacteraemia (MRSAB) is a serious illness and associated with complications tha...
Uncomplicated Streptococcal Bacteremia: The Era of Oral Antibiotic Step-down Therapy?
Mucormycosis is an uncommon invasive fungal disease with high mortality and few treatment options. Isavuconazole is a tria...
Off-label use versus formal recommendations of conventional and novel antibiotics for the treatment of infections caused by multidrug-resistant bacteria
The infections caused by multidrug- and extensively drug-resistant (MDR, XDR) bacteria, including Gram-positive cocci (GPC...
A novel method to evaluate ceftazidime/avibactam therapy in patients with carbapenemase-producing Enterobactericeae (CPE) bloodstream infections
The widespread of carbapenemase-producing Enterobacterales (CPE) is a worrisome health concern, and represents one of the ...
Pharmacokinetic/pharmacodynamic of ceftobiprole in patients on ECMO
Available online 18 February 2023, 106765Author links open overlay panel, , , , , , , , , , , ABSTRACTBackgroundDue to its...
Outcomes Associated with Empiric Cefepime for Bloodstream Infections Caused by Ceftriaxone-Resistant, Cefepime-Susceptible Escherichia coli and Klebsiella pneumoniae
Extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) are becoming alarmingly prevalent and difficult to ma...
Low levels of tenofovir in breast milk support breastfeeding in HBV-infected mothers treated with tenofovir disoproxil fumarate
Chronic hepatitis B virus (HBV) infection is a significant risk factor for liver cirrhosis and hepatocellular cancer [1]. ...
Antimicrobial Activity of Tebipenem and Comparators against Enterobacterales from diverse Outpatient Centers and Nursing Homes in the United States
There is uncertainty about whether piperacillin/tazobactam (PT) increases the risk of acute kidney injury (AKI) in patient...
In vitro antibacterial activity of omeprazole and esomeprazole in combination with ciprofloxacin as an alternative to repositioning against ESKAPE and evaluation of plasmid DNA cleavage capacity
Available online 10 February 2023, 106753Author links open overlay panel, , , , , , , Section snippetsAuthors' contributio...
Nafcillin Augmentation of Daptomycin and Cathelicidin LL-37 Killing of Methicillin-resistant Staphylococcus epidermidis: Foundations of Successful Therapy of Endocarditis
Driven by an increasing population of patients with long-term intravascular access devices, coagulase-negative staphylococ...
Population pharmacokinetics of levornidazole in healthy subjects and patients and sequential dosing regimen proposal using pharmacokinetic/pharmacodynamic analysis
Levornidazole, the levo-isomer of ornidazole, is a third-generation nitroimidazole derivative developed after metronidazol...
Propensity-matched analysis of the protective effect of ticagrelor versus clopidogrel on the risk of developing Staphylococcus aureus bacteremia
Despite advances in medical care and development of novel antistaphylococcal agents, Staphylococcus aureus bacteremia (SAB...
Within-host resistance evolution of a fatal ST11 hypervirulent carbapenem-resistant Klebsiella pneumoniae
Carbapenem-resistant Klebsiella pneumoniae (CRKp) has been a critical threat to public health [1]. Clonal complex 258 (CC2...
Population Pharmacokinetics and Pharmacodynamics of Cefazolin Using Total and Unbound Serum Concentrations in Patients with High Body Weight
The study objective was to evaluate the steady-state pharmacokinetics and pharmacodynamics of cefazolin in patients with l...
REDS study: Retrospective Effectiveness study of Dalbavancin and other Standard of Care of the same class in patients with ABSSSI
Acute bacterial skin and skin-structure infections (ABSSSIs) are a common source of morbidity in both the community and th...
National surveillance of antimicrobial susceptibilities to ceftaroline, dalbavancin, telavancin, tedizolid, eravacycline, omadacycline, and other comparator antibiotics and genetic characteristics of bacteremic Staphylococcus aureus isolates in adults: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) programme in 2020
Methicillin-resistant Staphylococcus aureus (MRSA) was first described in the 1960s, with an increased prevalence of hospi...
Dalbavancin as sequential therapy for infective endocarditis due to Gram-positive organisms: A review
Infective endocarditis is a potentially life-threatening infection, with an increasing incidence.1 It is predominantly a G...
Voriconazole exposure is influenced by inflammation: a population pharmacokinetic model
BackgroundVoriconazole is an antifungal drug used for the treatment of invasive fungal infections. Due to highly variable ...
Isavuconazole dosing in Asian patients with invasive mould infections – is there a role for therapeutic drug monitoring?
Available online 8 February 2023, 106748Author links open overlay panel, , , , , , , , , , , Section snippetsFundingThis w...
Comparative Activity of Newer β-Lactam/β-Lactamase Inhibitor Combinations against Pseudomonas aeruginosa Isolates from United States Medical Centers (2020-2021)
Pseudomonas aeruginosa is a common cause of healthcare-associated infections, including pneumonia, skin and skin structure...
Activity of aztreonam in combination with novel β-lactamase inhibitors against metallo-β-lactamase-producing Enterobacterales from Spain
Infections caused by metallo-β-lactamase (MBL)-producing Enterobacterales are increasing globally at an alarming rate [1]....
ICEGpa1804, a Novel Integrative and Conjugative Element carrying eight resistance genes, Identified in Glaesserella parasuis
Available online 2 February 2023, 106740Author links open overlay panel, , , , , , , AbstractICEGpa1804 was identified in ...
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