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Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro
Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro
Influenza H7N9 virus causes human infections with about 40% case fatality rate. The severe cases usually present with pneu...
HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34+ hematopoietic progenitor cells
HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34+ hematopoietic progenitor cells
ABSTRACT Human cytomegalovirus (HCMV) is a species-specific virus that establishes a persistent/latent infection in CD34+ ...
Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates
Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates
ABSTRACT The reservoir of HIV-infected cells that persist in the face of effective anti-retroviral therapy (ART) is the ba...
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8
ABSTRACT Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an u...
N-linked glycoproteins and host proteases are involved in swine acute diarrhea syndrome coronavirus entry
N-linked glycoproteins and host proteases are involved in swine acute diarrhea syndrome coronavirus entry
ABSTRACTSwine acute diarrhea syndrome coronavirus (SADS-CoV) is highly pathogenic to piglets and poses a major threat to t...
Single-molecule-binding studies of antivirals targeting the hepatitis C virus core protein
Single-molecule-binding studies of antivirals targeting the hepatitis C virus core protein
ABSTRACT The hepatitis C virus (HCV) core protein (HCVcp) is the most highly conserved protein encoded by the HCV genome, ...
Interferon regulatory factor 7 modulates virus clearance and immune responses to alphavirus encephalomyelitis
Interferon regulatory factor 7 modulates virus clearance and immune responses to alphavirus encephalomyelitis
ABSTRACT Central nervous system (CNS) infection with Sindbis virus (SINV), the prototypic alphavirus, results in encephalo...
Construction of a diagnostic model for hepatitis B-related hepatocellular carcinoma using machine learning and artificial neural networks and revealing the correlation by immunoassay
Construction of a diagnostic model for hepatitis B-related hepatocellular carcinoma using machine learning and artificial neural networks and revealing the correlation by immunoassay
HBV infection profoundly escalates hepatocellular carcinoma (HCC) susceptibility, responsible for a majority of HCC cases....
Genetic variation of E6 and E7 genes of human papillomavirus type 16 from central China
Genetic variation of E6 and E7 genes of human papillomavirus type 16 from central China
Persistent high-risk human papillomavirus (HR-HPV) infection is an important factor in the development of cervical cancer,...
Evaluation of semen DNA integrity and related parameters with COVID-19 infection: a prospective cohort study
Evaluation of semen DNA integrity and related parameters with COVID-19 infection: a prospective cohort study
In the context of Corona Virus Disease 2019 (COVID-19) global pandemic, Its impact on male reproductive function should be...
Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus
Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus
ABSTRACT Alphaviruses are emerging and re-emerging viruses that cause severe disease and threaten public health worldwide....
Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus
Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus
ABSTRACTAfrican swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating disease that affects dom...
Polydatin alleviates mycoplasma pneumoniae-induced injury via inhibition of Caspase-1/GSDMD-dependent pyroptosis
Polydatin alleviates mycoplasma pneumoniae-induced injury via inhibition of Caspase-1/GSDMD-dependent pyroptosis
Mycoplasma pneumoniae (MP) is one of the main pathogens causing community acquired pneumonia (CAP) in children and adults....
Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein
Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein
ABSTRACT Molecular interactions between viral DNA and viral-encoded protein are a prerequisite for successful herpesvirus ...
Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda
Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda
ABSTRACT Uganda experienced five Ebola disease outbreaks caused by Bundibugyo virus (n = 1) and Sudan virus (SUDV) (n = 4)...
Herpes simplex virus 1 immediate early transcription initiation, pause-release, elongation, and termination in the presence and absence of ICP4
Herpes simplex virus 1 immediate early transcription initiation, pause-release, elongation, and termination in the presence and absence of ICP4
ABSTRACT Herpes simplex virus 1 (HSV-1) transcription is tightly regulated in a temporal cascade, utilizing cellular RNA p...
Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles
Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles
ABSTRACT Capsid assembly modulators (CAMs) are a novel class of therapeutic small molecules with the potential to address ...
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins
ABSTRACT The phosphoinositide 3-kinase (PI3K)/AKT pathway plays crucial roles in cell viability and protein synthesis and ...
Conditional replication and secretion of hepatitis B virus genome uncover the truncated 3′ terminus of encapsidated viral pregenomic RNA
Conditional replication and secretion of hepatitis B virus genome uncover the truncated 3′ terminus of encapsidated viral pregenomic RNA
ABSTRACT Hepatitis B virus (HBV) pregenomic RNA (pgRNA) is packaged into capsid where reverse transcription takes place to...
Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity
Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity
ABSTRACT Influenza A viruses (IAVs) contain sialoglycan-binding hemagglutinin (HA) and sialoglycan-cleaving neuraminidase ...
Prohibitin1 facilitates viral replication by impairing the RIG-I-like receptor signaling pathway
Prohibitin1 facilitates viral replication by impairing the RIG-I-like receptor signaling pathway
ABSTRACT Innate immunity plays an essential role in defending the host against pathogenic infections. Appropriate controls...
Host genetic variation at a locus near CHD1L impacts HIV sequence diversity in a South African population
Host genetic variation at a locus near CHD1L impacts HIV sequence diversity in a South African population
ABSTRACT There is variability in viral load (VL) among individuals with untreated human immunodeficiency virus (HIV) infec...
Reovirus genomic diversity confers plasticity for protease utility during adaptation to intracellular uncoating
Reovirus genomic diversity confers plasticity for protease utility during adaptation to intracellular uncoating
ABSTRACT Mammalian orthoreoviruses (reoviruses) infect many mammals and provide a safe model to study enteric viruses. Kno...
A study to assess the impact of the cobas point-of-care RT-PCR assay (SARS-CoV-2 and Influenza A/B) on patient clinical management in the emergency department of the University of California at Davis Medical Center
A study to assess the impact of the cobas point-of-care RT-PCR assay (SARS-CoV-2 and Influenza A/B) on patient clinical management in the emergency department of the University of California at Davis Medical Center
Volume 168, November 2023, 105597Author links open overlay panel, , , , Highlights•Point-of-care (POC) testing reduced ord...
Abstracts of the 19th International Symposium on NeuroVirology October 2–5, 2023 Montreal, Quebec, Canada
Abstracts of the 19th International Symposium on NeuroVirology October 2–5, 2023 Montreal, Quebec, Canada
Cite this article Abstracts of the 19th International Symposium on NeuroVirology October 2–5, 2023 Montreal, Quebec, Canad...
Detection of early phase human T-cell leukemia virus type 1 and 2 infection with an improved confirmatory test
Detection of early phase human T-cell leukemia virus type 1 and 2 infection with an improved confirmatory test
Volume 168, November 2023, 105598Author links open overlay panel, , , Highlights•Alternative secondary antibodies enabled ...
DENV-1 genotype V linked to the 2022 dengue epidemic in Southern Brazil
DENV-1 genotype V linked to the 2022 dengue epidemic in Southern Brazil
Dengue is a viral disease transmitted to humans by infected mosquitoes being Aedes aegypti the primary vector. Belonging t...
Clinical presentation of human monkeypox virus infection during the 2022 outbreak: descriptive case series from a large italian Research Hospital
Clinical presentation of human monkeypox virus infection during the 2022 outbreak: descriptive case series from a large italian Research Hospital
In May 2022, a new case of Monkeypox Virus (MPX) was reported in a non-endemic area, the United Kingdom, and since then, t...
Complete genome analysis of echovirus 30 strains isolated from hand-foot-and-mouth disease in Yunnan province, China
Complete genome analysis of echovirus 30 strains isolated from hand-foot-and-mouth disease in Yunnan province, China
Echovirus 30 is prone to cause hand-foot-and-mouth disease in infants and children. However, molecular epidemiologic infor...
Investigating the interactions of endornaviruses with each other and with other viruses in common bean, Phaseolus vulgaris
Investigating the interactions of endornaviruses with each other and with other viruses in common bean, Phaseolus vulgaris
Plant viruses of the genus Alphaendornavirus are transmitted solely via seed and pollen and generally cause no apparent di...
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