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Comprehensive multi-omics analysis of the m7G in pan-cancer from the perspective of predictive, preventive, and personalized medicine
The N7-methylguanosine modification (m7G) of the 5′ cap structure in the mRNA plays a crucial role in gene expressio...
Predictive, preventive, and personalized management of retinal fluid via computer-aided detection app for optical coherence tomography scans
Computer-aided detection systems for retinal fluid could be beneficial for disease monitoring and management by chronic ag...
Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach
Due to the reactive medical approach applied to disease management, stroke has reached an epidemic scale worldwide. In 201...
Identification of FERMT1 and SGCD as key marker in acute aortic dissection from the perspective of predictive, preventive, and personalized medicine
Acute aortic dissection (AAD) is a severe aortic injury disease, which is often life-threatening at the onset. However, it...
Radiomics based on readout-segmented echo-planar imaging (RS-EPI) diffusion-weighted imaging (DWI) for prognostic risk stratification of patients with rectal cancer: a two-centre, machine learning study using the framework of predictive, preventive, and personalized medicine
Currently, the rate of recurrence or metastasis (ROM) remains high in rectal cancer (RC) patients treated with the standar...
Predictive genomic tools in disease stratification and targeted prevention: a recent update in personalized therapy advancements
In the current era of medical revolution, genomic testing has guided the healthcare fraternity to develop predictive, prev...
DNA and histone modifications as potent diagnostic and therapeutic targets to advance non-small cell lung cancer management from the perspective of 3P medicine
Lung cancer has a very high mortality in females and males. Most (~ 85%) of lung cancers are non-small cell lung can...
Comprehensive analysis of autoimmune-related genes in amyotrophic lateral sclerosis from the perspective of 3P medicine
Although growing evidence suggests close correlations between autoimmunity and amyotrophic lateral sclerosis (ALS), no stu...
Mutual effect of homocysteine and uric acid on arterial stiffness and cardiovascular risk in the context of predictive, preventive, and personalized medicine
Arterial stiffness is a major risk factor and effective predictor of cardiovascular diseases and a common pathway of patho...
Hair cortisol level might be indicative for a 3PM approach towards suicide risk assessment in depression: comparative analysis of mentally stable and depressed individuals versus individuals after completing suicide
Depression and suicidal behavior are interrelated, stress-associated mental health conditions, each lacking biological ver...
Correction to: A nomogram model for the risk prediction of type 2 diabetes in healthy eastern China residents: a 14‑year retrospective cohort study from 15,166 participants
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which ...
Pre-pregnancy check-up of maternal vascular status and associated phenotype is crucial for the health of mother and offspring
Cardiovascular disease remains the leading cause of disease burden globally with far-reaching consequences including enorm...
Antithrombotic and antiplatelet effects of plant-derived compounds: a great utility potential for primary, secondary, and tertiary care in the framework of 3P medicine
Thromboembolism is the third leading vascular disease, with a high annual incidence of 1 to 2 cases per 1000 individuals w...
A nomogram model for the risk prediction of type 2 diabetes in healthy eastern China residents: a 14-year retrospective cohort study from 15,166 participants
Risk prediction models can help identify individuals at high risk for type 2 diabetes. However, no such model has been app...
Oculomics for sarcopenia prediction: a machine learning approach toward predictive, preventive, and personalized medicine
Sarcopenia is characterized by a gradual loss of skeletal muscle mass and strength with increased adverse outcomes. Recent...
Sleep apnea predicts cardiovascular death in patients with Marfan syndrome: a cohort study
Surgical replacement of the aortic root is the only intervention that can prevent aortic dissection and cardiovascular dea...
Identifying potential signatures for atherosclerosis in the context of predictive, preventive, and personalized medicine using integrative bioinformatics approaches and machine-learning strategies
Atherosclerosis is a major contributor to morbidity and mortality worldwide. Although several molecular markers associated...
Prognostic significance of pretreatment red blood cell distribution width in primary diffuse large B-cell lymphoma of the central nervous system for 3P medical approaches in multiple cohorts
Predicting the clinical outcomes of primary diffuse large B-cell lymphoma of the central nervous system (PCNS-DLBCL) to me...
Anti-prostate cancer protection and therapy in the framework of predictive, preventive and personalised medicine — comprehensive effects of phytochemicals in primary, secondary and tertiary care
According to the GLOBOCAN 2020, prostate cancer (PCa) is the most often diagnosed male cancer in 112 countries and the lea...
TMEM92 acts as an immune-resistance and prognostic marker in pancreatic cancer from the perspective of predictive, preventive, and personalized medicine
Pancreatic cancer presents extremely poor prognosis due to the difficulty of early diagnosis, low resection rate, and high...
Metagenomic analysis of the microbiome of the upper reproductive tract: combating ovarian cancer through predictive, preventive, and personalized medicine
We investigated whether ovarian cancer could alter the genital microbiota in a specific way with clinical values. Furtherm...
Digital biomarkers and sex impacts in Alzheimer’s disease management — potential utility for innovative 3P medicine approach
Digital biomarkers are defined as objective, quantifiable physiological and behavioral data that are collected and measure...
Tangled quest of post-COVID-19 infection-caused neuropathology and what 3P nano-bio-medicine can solve?
COVID-19-caused neurological problems are the important post-CoV-2 infection complications, which are recorded in ~&...
Rapid triage for ischemic stroke: a machine learning-driven approach in the context of predictive, preventive and personalised medicine
Recognising the early signs of ischemic stroke (IS) in emergency settings has been challenging. Machine learning (ML), a r...
Implementing a preimplantation proteomic approach to advance assisted reproduction technologies in the framework of predictive, preventive, and personalized medicine
The evolution of the field of assisted reproduction technology (ART) in the last 40 years has significantly contributed to...
Methods to evaluate vascular function: a crucial approach towards predictive, preventive, and personalised medicine
Endothelium, the gatekeeper of our blood vessels, is highly heterogeneous and a crucial physical barrier with the ability ...
Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine
Mitochondria are the “gatekeeper” in a wide range of cellular functions, signaling events, cell homeostasis, p...
Comprehensive analysis of spliceosome genes and their mutants across 27 cancer types in 9070 patients: clinically relevant outcomes in the context of 3P medicine
Spliceosome machinery plays important roles in cell biological processes, and its alterations are significantly associated...
Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer management is associated with...
Glycomic biomarkers are instrumental for suboptimal health status management in the context of predictive, preventive, and personalized medicine
Suboptimal health status (SHS), a reversible borderline condition between optimal health status and disease, has been reco...
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