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Development and validation of a routine blood parameters-based model for screening the occurrence of retinal detachment in high myopia in the context of PPPM
Timely detection and treatment of retinal detachment (RD) could effectively save vision and reduce the risk of progressing...
Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities — preliminary data for PPPM validation
Type 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-dependent, comprises over 95% of all ...
Multi-omics and immune cells’ profiling of COVID-19 patients for ICU admission prediction: in silico analysis and an integrated machine learning-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Intensive care unit admission (ICUA) triage has been urgent need for solving the shortage of ICU beds, during the coronavi...
Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent complication of diabetes mell...
Vascular dysregulation in glaucoma: retinal vasoconstriction and normal neurovascular coupling in altitudinal visual field defects
Vision loss in glaucoma is not only associated with elevated intraocular pressure and neurodegeneration, but vascular dysr...
New insight of metabolomics in ocular diseases in the context of 3P medicine
Metabolomics refers to the high-through untargeted or targeted screening of metabolites in biofluids, cells, and tissues. ...
Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms
Arterial aneurysms are life-threatening but usually asymptomatic before requiring hospitalization. Oculomics of retinal va...
Microsatellite instability assessment is instrumental for Predictive, Preventive and Personalised Medicine: status quo and outlook
A form of genomic alteration called microsatellite instability (MSI) occurs in a class of tandem repeats (TRs) called micr...
Clarifying sleep characteristics and analyzing risk factors of sleep disorders to promote a predictive, preventive, and personalized medicine in patients with burn scars
This study assessed sleep quality in patients with burn scars and investigated risk factors of sleep disorders to guide cl...
Association of IgG N-glycomics with prevalent and incident type 2 diabetes mellitus from the paradigm of predictive, preventive, and personalized medicine standpoint
Type 2 diabetes mellitus (T2DM), a major metabolic disorder, is expanding at a rapidly rising worldwide prevalence and has...
Diagnostic accuracy of autoverification and guidance system for COVID-19 RT-PCR results
To date, most countries worldwide have declared that the pandemic of COVID-19 is over, while the WHO has not officially en...
Global burden of cancers attributable to tobacco smoking, 1990–2019: an ecological study
Identifying risk factors for cancer initiation and progression is the cornerstone of the preventive approach to cancer man...
Body mass index–based predictions and personalized clinical strategies for colorectal cancer in the context of PPPM
Currently colorectal cancer (CRC) is the third most prevalent cancer worldwide. Body mass index (BMI) is frequently used i...
Comprehensive multi-omics analysis of the m7G in pan-cancer from the perspective of predictive, preventive, and personalized medicine
The N7-methylguanosine modification (m7G) of the 5′ cap structure in the mRNA plays a crucial role in gene expressio...
Predictive, preventive, and personalized management of retinal fluid via computer-aided detection app for optical coherence tomography scans
Computer-aided detection systems for retinal fluid could be beneficial for disease monitoring and management by chronic ag...
Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach
Due to the reactive medical approach applied to disease management, stroke has reached an epidemic scale worldwide. In 201...
Identification of FERMT1 and SGCD as key marker in acute aortic dissection from the perspective of predictive, preventive, and personalized medicine
Acute aortic dissection (AAD) is a severe aortic injury disease, which is often life-threatening at the onset. However, it...
Radiomics based on readout-segmented echo-planar imaging (RS-EPI) diffusion-weighted imaging (DWI) for prognostic risk stratification of patients with rectal cancer: a two-centre, machine learning study using the framework of predictive, preventive, and personalized medicine
Currently, the rate of recurrence or metastasis (ROM) remains high in rectal cancer (RC) patients treated with the standar...
Predictive genomic tools in disease stratification and targeted prevention: a recent update in personalized therapy advancements
In the current era of medical revolution, genomic testing has guided the healthcare fraternity to develop predictive, prev...
DNA and histone modifications as potent diagnostic and therapeutic targets to advance non-small cell lung cancer management from the perspective of 3P medicine
Lung cancer has a very high mortality in females and males. Most (~ 85%) of lung cancers are non-small cell lung can...
Comprehensive analysis of autoimmune-related genes in amyotrophic lateral sclerosis from the perspective of 3P medicine
Although growing evidence suggests close correlations between autoimmunity and amyotrophic lateral sclerosis (ALS), no stu...
Mutual effect of homocysteine and uric acid on arterial stiffness and cardiovascular risk in the context of predictive, preventive, and personalized medicine
Arterial stiffness is a major risk factor and effective predictor of cardiovascular diseases and a common pathway of patho...
Hair cortisol level might be indicative for a 3PM approach towards suicide risk assessment in depression: comparative analysis of mentally stable and depressed individuals versus individuals after completing suicide
Depression and suicidal behavior are interrelated, stress-associated mental health conditions, each lacking biological ver...
Correction to: A nomogram model for the risk prediction of type 2 diabetes in healthy eastern China residents: a 14‑year retrospective cohort study from 15,166 participants
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which ...
Pre-pregnancy check-up of maternal vascular status and associated phenotype is crucial for the health of mother and offspring
Cardiovascular disease remains the leading cause of disease burden globally with far-reaching consequences including enorm...
Antithrombotic and antiplatelet effects of plant-derived compounds: a great utility potential for primary, secondary, and tertiary care in the framework of 3P medicine
Thromboembolism is the third leading vascular disease, with a high annual incidence of 1 to 2 cases per 1000 individuals w...
A nomogram model for the risk prediction of type 2 diabetes in healthy eastern China residents: a 14-year retrospective cohort study from 15,166 participants
Risk prediction models can help identify individuals at high risk for type 2 diabetes. However, no such model has been app...
Oculomics for sarcopenia prediction: a machine learning approach toward predictive, preventive, and personalized medicine
Sarcopenia is characterized by a gradual loss of skeletal muscle mass and strength with increased adverse outcomes. Recent...
Sleep apnea predicts cardiovascular death in patients with Marfan syndrome: a cohort study
Surgical replacement of the aortic root is the only intervention that can prevent aortic dissection and cardiovascular dea...
Identifying potential signatures for atherosclerosis in the context of predictive, preventive, and personalized medicine using integrative bioinformatics approaches and machine-learning strategies
Atherosclerosis is a major contributor to morbidity and mortality worldwide. Although several molecular markers associated...
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