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Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Acute pain is a physiologic, protective life-important warning neurological signal indicating multi-level tissue modulatio...
Observational and genetic associations between cardiorespiratory fitness and age-related diseases: longitudinal analyses in the UK Biobank study
Observational and genetic associations between cardiorespiratory fitness and age-related diseases: longitudinal analyses in the UK Biobank study
Observational studies have indicated that increased cardiorespiratory fitness is associated with a decreased risk of cardi...
3PM-guided innovation in treatments of severe alcohol-associated hepatitis utilizing fecal microbiota transplantation
3PM-guided innovation in treatments of severe alcohol-associated hepatitis utilizing fecal microbiota transplantation
Severe alcohol-associated hepatitis (SAH) is the most critical, acute, inflammatory phenotype within the alcohol-associate...
The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation
The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation
Gut microbiota (GM) is closely associated with the onset of depression, in which inflammation plays an essential role. Ide...
Resveratrol: potential application in safeguarding testicular health
Resveratrol: potential application in safeguarding testicular health
Factors such as increasing mental pressure and poor living habits in modern society have led to an increase in the inciden...
Application of ChatGPT-4 to oculomics: a cost-effective osteoporosis risk assessment to enhance management as a proof-of-principles model in 3PM
Application of ChatGPT-4 to oculomics: a cost-effective osteoporosis risk assessment to enhance management as a proof-of-principles model in 3PM
Oculomics is an emerging medical field that focuses on the study of the eye to detect and understand systemic diseases. Ch...
Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
Hypertension (HTN) is a prevalent global health concern. From the standpoint of preventive and personalized medicine (PPPM...
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Clinical data are essential for developing cloud platforms for intelligent diagnosis and treatment decision of diseases. H...
Artificial intelligence in ovarian cancer drug resistance advanced 3PM approach: subtype classification and prognostic modeling
Artificial intelligence in ovarian cancer drug resistance advanced 3PM approach: subtype classification and prognostic modeling
Ovarian cancer patients’ resistance to first-line treatment posed a significant challenge, with approximately 70% ex...
Liver function maximum capacity test during normothermic regional perfusion predicts graft function after transplantation
Liver function maximum capacity test during normothermic regional perfusion predicts graft function after transplantation
In an effort to reduce waitlist mortality, extended criteria donor organs, including those from donation after circulatory...
The caregiving role influences Suboptimal Health Status and psychological symptoms in unpaid carers
The caregiving role influences Suboptimal Health Status and psychological symptoms in unpaid carers
Suboptimal Health Status (SHS) is the physical state between health and disease. This study aimed to fill in the knowledge...
Unraveling progression subtypes in people with Huntington’s disease
Unraveling progression subtypes in people with Huntington’s disease
Huntington’s disease (HD) is a progressive neurodegenerative disease caused by a CAG trinucleotide expansion in the ...
Rhodiola rosea: a review in the context of PPPM approach
Rhodiola rosea: a review in the context of PPPM approach
A natural “medicine and food” plant, Rhodiola rosea (RR) is primarily made up of organic acids, phenolic compo...
Clinically relevant immune subtypes based on alternative splicing landscape of immune-related genes for lung cancer advanced PPPM approach
Clinically relevant immune subtypes based on alternative splicing landscape of immune-related genes for lung cancer advanced PPPM approach
Alternative splicing (AS) occurs in the process of gene post-transcriptional process, which is very important for the corr...
Digital biomarkers: 3PM approach revolutionizing chronic disease management — EPMA 2024 position
Digital biomarkers: 3PM approach revolutionizing chronic disease management — EPMA 2024 position
Non-communicable chronic diseases (NCDs) have become a major global health concern. They constitute the leading cause of d...
Multi-risk factors joint prediction model for risk prediction of retinopathy of prematurity
Multi-risk factors joint prediction model for risk prediction of retinopathy of prematurity
Retinopathy of prematurity (ROP) is a retinal vascular proliferative disease common in low birth weight and premature infa...
Social determinants of health and their relation to suboptimal health status in the context of 3PM: a latent profile analysis
Social determinants of health and their relation to suboptimal health status in the context of 3PM: a latent profile analysis
Suboptimal health is identified as a reversible phase occurring before chronic diseases manifest, emphasizing the signific...
Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care—clinically relevant 3PM innovation
Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care—clinically relevant 3PM innovation
Despite their subordination in humans, to a great extent, mitochondria maintain their independent status but tightly coope...
Mediterranean diet in the targeted prevention and personalized treatment of chronic diseases: evidence, potential mechanisms, and prospects
Mediterranean diet in the targeted prevention and personalized treatment of chronic diseases: evidence, potential mechanisms, and prospects
The prevalence of chronic diseases is currently a major public health issue worldwide and is exploding with the population...
Clinically relevant stratification of lung squamous carcinoma patients based on ubiquitinated proteasome genes for 3P medical approach
Clinically relevant stratification of lung squamous carcinoma patients based on ubiquitinated proteasome genes for 3P medical approach
The proteasome is a crucial mechanism that regulates protein fate and eliminates misfolded proteins, playing a significant...