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Development and validation of a short-form suboptimal health status questionnaire
Development and validation of a short-form suboptimal health status questionnaire
Suboptimal health status (SHS) is a reversible, borderline state between optimal health and disease. Although this conditi...
Identification of novel serum protein biomarkers in the context of 3P medicine for intravenous leiomyomatosis: a data-independent acquisition mass spectrometry-based proteomics study
Identification of novel serum protein biomarkers in the context of 3P medicine for intravenous leiomyomatosis: a data-independent acquisition mass spectrometry-based proteomics study
Intravenous leiomyomatosis (IVL) is a rare endocrine-associated tumor with unique characteristics of intravascular invasio...
Machine learning–couched treatment algorithms tailored to individualized profile of patients with primary anterior chamber angle closure predisposed to the glaucomatous optic neuropathy
Machine learning–couched treatment algorithms tailored to individualized profile of patients with primary anterior chamber angle closure predisposed to the glaucomatous optic neuropathy
Primary angle closure glaucoma (PACG) is still one of the leading causes of irreversible blindness, with a trend towards a...
Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach
Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach
Hepatic carcinoma is one of the most common types of malignant tumors in the digestive system, and its biological characte...
The correlation between primary open-angle glaucoma (POAG) and gut microbiota: a pilot study towards predictive, preventive, and personalized medicine
The correlation between primary open-angle glaucoma (POAG) and gut microbiota: a pilot study towards predictive, preventive, and personalized medicine
Glaucoma is the leading cause of irreversible blindness worldwide. Emerged evidence has shown that glaucoma is considered ...
Identifying oxidative stress-related biomarkers in idiopathic pulmonary fibrosis in the context of predictive, preventive, and personalized medicine using integrative omics approaches and machine-learning strategies
Identifying oxidative stress-related biomarkers in idiopathic pulmonary fibrosis in the context of predictive, preventive, and personalized medicine using integrative omics approaches and machine-learning strategies
Idiopathic pulmonary fibrosis (IPF) is a rare interstitial lung disease with a poor prognosis that currently lacks effecti...
Royal jelly: a predictive, preventive and personalised strategy for novel treatment options in non-communicable diseases
Royal jelly: a predictive, preventive and personalised strategy for novel treatment options in non-communicable diseases
Royal jelly (RJ) is a bee product produced by young adult worker bees, composed of water, proteins, carbohydrates and lipi...
COVID-19 lessons to protect populations against future pandemics by implementing PPPM principles in healthcare
COVID-19 lessons to protect populations against future pandemics by implementing PPPM principles in healthcare
The coronavirus disease 2019 (COVID-19) pandemic has continued for more than 3 years, placing a huge burden on so...
Anatomic characteristics of shoulder based on MRI accurately predict incomplete rotator cuff injuries in patients: relevance for predictive, preventive, and personalized healthcare strategies
Anatomic characteristics of shoulder based on MRI accurately predict incomplete rotator cuff injuries in patients: relevance for predictive, preventive, and personalized healthcare strategies
In the diagnosis of incomplete rotator cuff injuries (IRCI), magnetic resonance imaging (MRI) and ultrasound examination o...
Genetically predicted the causal relationship between gut microbiota and infertility: bidirectional Mendelian randomization analysis in the framework of predictive, preventive, and personalized medicine
Genetically predicted the causal relationship between gut microbiota and infertility: bidirectional Mendelian randomization analysis in the framework of predictive, preventive, and personalized medicine
Several studies have reported the association between gut microbiota and infertility; however, the causal association betw...
Ubiquitinomics revealed disease- and stage-specific patterns relevant for the 3PM approach in human sigmoid colon cancers
Ubiquitinomics revealed disease- and stage-specific patterns relevant for the 3PM approach in human sigmoid colon cancers
The patients with sigmoid colorectal cancer commonly show high mortality and poor prognosis. Increasing evidence has demon...
Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors
Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors
Human growth hormone (GH) is the indispensable hormone for the maintenance of normal physiological functions of the human ...
Quality of life and cost-effectiveness of different breast cancer surgery procedures: a Markov decision tree-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Quality of life and cost-effectiveness of different breast cancer surgery procedures: a Markov decision tree-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Breast cancer is a complex disease with heterogeneous outcomes that may benefit from the implementation of Predictive, Pre...
Mechanical power normalized to aerated lung predicts noninvasive ventilation failure and death and contributes to the benefits of proning in COVID-19 hypoxemic respiratory failure
Mechanical power normalized to aerated lung predicts noninvasive ventilation failure and death and contributes to the benefits of proning in COVID-19 hypoxemic respiratory failure
Concern exists that noninvasive ventilation (NIV) may promote ventilation-induced lung injury(VILI) and worsen outcome in ...
Multi-omics identification of an immunogenic cell death-related signature for clear cell renal cell carcinoma in the context of 3P medicine and based on a 101-combination machine learning computational framework
Multi-omics identification of an immunogenic cell death-related signature for clear cell renal cell carcinoma in the context of 3P medicine and based on a 101-combination machine learning computational framework
Clear cell renal cell carcinoma (ccRCC) is a prevalent urological malignancy associated with a high mortality rate. The la...
Ideal cardiovascular health metrics and life expectancy free of cardiovascular diseases: a prospective cohort study
Ideal cardiovascular health metrics and life expectancy free of cardiovascular diseases: a prospective cohort study
Whether cardiovascular health (CVH) metrics impact longevity with and without cardiovascular diseases (CVDs) has not been ...
Clarifying the effect of gut microbiota on allergic conjunctivitis risk is instrumental for predictive, preventive, and personalized medicine: a Mendelian randomization analysis
Clarifying the effect of gut microbiota on allergic conjunctivitis risk is instrumental for predictive, preventive, and personalized medicine: a Mendelian randomization analysis
Allergic conjunctivitis is an ocular immune disease which affects the conjunctiva, eyelids, and cornea. Growing evidence i...
Underexplored reciprocity between genome-wide methylation status and long non-coding RNA expression reflected in breast cancer research: potential impacts for the disease management in the framework of 3P medicine
Underexplored reciprocity between genome-wide methylation status and long non-coding RNA expression reflected in breast cancer research: potential impacts for the disease management in the framework of 3P medicine
Breast cancer (BC) is the most common female malignancy reaching a pandemic scale worldwide. A comprehensive interplay bet...
Multi-faceted CRISPR/Cas technological innovation aspects in the framework of 3P medicine
Multi-faceted CRISPR/Cas technological innovation aspects in the framework of 3P medicine
Since 2009, the European Association for Predictive, Preventive and Personalised Medicine (EPMA, Brussels) promot...
Identification of potential necroinflammation-associated necroptosis-related biomarkers for delayed graft function and renal allograft failure: a machine learning-based exploration in the framework of predictive, preventive, and personalized medicine
Identification of potential necroinflammation-associated necroptosis-related biomarkers for delayed graft function and renal allograft failure: a machine learning-based exploration in the framework of predictive, preventive, and personalized medicine
Delayed graft function (DGF) is one of the key post-operative challenges for a subset of kidney transplantation (KTx) pati...
Development and validation of a routine blood parameters-based model for screening the occurrence of retinal detachment in high myopia in the context of PPPM
Development and validation of a routine blood parameters-based model for screening the occurrence of retinal detachment in high myopia in the context of PPPM
Timely detection and treatment of retinal detachment (RD) could effectively save vision and reduce the risk of progressing...
Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities — preliminary data for PPPM validation
Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities — preliminary data for PPPM validation
Type 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-dependent, comprises over 95% of all ...
Multi-omics and immune cells’ profiling of COVID-19 patients for ICU admission prediction: in silico analysis and an integrated machine learning-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Multi-omics and immune cells’ profiling of COVID-19 patients for ICU admission prediction: in silico analysis and an integrated machine learning-based approach in the framework of Predictive, Preventive, and Personalized Medicine
Intensive care unit admission (ICUA) triage has been urgent need for solving the shortage of ICU beds, during the coronavi...
Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent complication of diabetes mell...
Vascular dysregulation in glaucoma: retinal vasoconstriction and normal neurovascular coupling in altitudinal visual field defects
Vascular dysregulation in glaucoma: retinal vasoconstriction and normal neurovascular coupling in altitudinal visual field defects
Vision loss in glaucoma is not only associated with elevated intraocular pressure and neurodegeneration, but vascular dysr...
New insight of metabolomics in ocular diseases in the context of 3P medicine
New insight of metabolomics in ocular diseases in the context of 3P medicine
Metabolomics refers to the high-through untargeted or targeted screening of metabolites in biofluids, cells, and tissues. ...
Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms
Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms
Arterial aneurysms are life-threatening but usually asymptomatic before requiring hospitalization. Oculomics of retinal va...
Microsatellite instability assessment is instrumental for Predictive, Preventive and Personalised Medicine: status quo and outlook
Microsatellite instability assessment is instrumental for Predictive, Preventive and Personalised Medicine: status quo and outlook
A form of genomic alteration called microsatellite instability (MSI) occurs in a class of tandem repeats (TRs) called micr...
Clarifying sleep characteristics and analyzing risk factors of sleep disorders to promote a predictive, preventive, and personalized medicine in patients with burn scars
Clarifying sleep characteristics and analyzing risk factors of sleep disorders to promote a predictive, preventive, and personalized medicine in patients with burn scars
This study assessed sleep quality in patients with burn scars and investigated risk factors of sleep disorders to guide cl...
Association of IgG N-glycomics with prevalent and incident type 2 diabetes mellitus from the paradigm of predictive, preventive, and personalized medicine standpoint
Association of IgG N-glycomics with prevalent and incident type 2 diabetes mellitus from the paradigm of predictive, preventive, and personalized medicine standpoint
Type 2 diabetes mellitus (T2DM), a major metabolic disorder, is expanding at a rapidly rising worldwide prevalence and has...
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