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Simulation of drug-drug interactions between breast cancer chemotherapeutic agents and antiemetic drugs
Simulation of drug-drug interactions between breast cancer chemotherapeutic agents and antiemetic drugs
Chemotherapy-induced nausea and vomiting are commonly experienced side effects in breast cancer (BCa) patients. Antiemetic...
Network pharmacology: a systems perspective possible underpinning approach for oral cancer treatment
Network pharmacology: a systems perspective possible underpinning approach for oral cancer treatment
Chandran U, Mehendale N, Patil S, Chaguturu R, Patwardhan B. Network Pharmacology. In: Patwardhan B, Chaguturu R, editors....
Cardiac safety profile of type II kinase inhibitors: Analysis of post-marketing reports from databases of European Medicine Agency & World Health Organization
Cardiac safety profile of type II kinase inhibitors: Analysis of post-marketing reports from databases of European Medicine Agency & World Health Organization
Targeted therapy with type II kinase inhibitors (KIs) is one of the preferred choices in cancer treatment. However, type I...
Fabrication, characterization and evaluation of a new designed botulinum toxin-cell penetrating peptide nanoparticulate complex
Fabrication, characterization and evaluation of a new designed botulinum toxin-cell penetrating peptide nanoparticulate complex
To have a better and longer effect, botulinum neurotoxin (BoNT) is injected several times in a treatment course, which cou...
Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies
Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies
This scoping review aims to present flavonoid compounds' promising effects and possible mechanisms of action on potent...
Fibroblast growth factor 2 reduces endoplasmic reticulum stress and apoptosis in in-vitro Non-Alcoholic Fatty Liver Disease model
Fibroblast growth factor 2 reduces endoplasmic reticulum stress and apoptosis in in-vitro Non-Alcoholic Fatty Liver Disease model
Non-Alcoholic fatty liver disease is characterized by the accumulation of excess fat in the liver, chronic inflammation, a...
Novel therapeutic approach for the treatment of cystic fibrosis based on freeze-dried tridrug microparticles to treat cystic fibrosis
Novel therapeutic approach for the treatment of cystic fibrosis based on freeze-dried tridrug microparticles to treat cystic fibrosis
Cystic fibrosis is a severe, autosomal recessive disease that shortens life expectancy. According to studies, approximatel...
Eradicating the tumor “seeds”: nanomedicines-based therapies against cancer stem cells
Eradicating the tumor “seeds”: nanomedicines-based therapies against cancer stem cells
Cancer stem cells (CSCs), a small subpopulation of cells with high tumorigenesis and strong intrinsic drug resistance, exh...
Resveratrol and Dulaglutide ameliorate adiposity and liver dysfunction in rats with diet-induced metabolic syndrome: Role of SIRT-1 / adipokines / PPARγ and IGF-1
Resveratrol and Dulaglutide ameliorate adiposity and liver dysfunction in rats with diet-induced metabolic syndrome: Role of SIRT-1 / adipokines / PPARγ and IGF-1
Adiposity and non-alcoholic fatty liver disease (NAFLD) are common characteristics of metabolic syndrome (MS). Understandi...
Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study
Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study
Drug-induced Stevens-Johnson syndrome (SJS) is a rare but life-threatening hypersensitivity reaction. Drug desensitization...
Lipid nanoparticles for gene therapy in ocular diseases
Lipid nanoparticles for gene therapy in ocular diseases
Lipid nanoparticles, as a nucleic acid delivery system, have been used as an alternative to treat ocular diseases, since t...
Safety assessment of the pharmacological excipient, diethylene glycol monoethyl ether (DEGEE), using in vitro and in vivo systems
Safety assessment of the pharmacological excipient, diethylene glycol monoethyl ether (DEGEE), using in vitro and in vivo systems
Cite this articleSrivastava, S., Mishra, S., Dewangan, J. et al. Safety assessment of the pharmacological excipient, dieth...
Availability and affordability of cardiovascular medicines in a major city of Afghanistan in 2020
Availability and affordability of cardiovascular medicines in a major city of Afghanistan in 2020
Affordable access to quality medicines is a critical target of global efforts to achieve universal health coverage. The ai...
Mesoporous silica coated SPIONs containing curcumin and silymarin intended for breast cancer therapy
Mesoporous silica coated SPIONs containing curcumin and silymarin intended for breast cancer therapy
Super-paramagnetic iron oxide nanoparticles (SPIONs) are known as promising theranostic nano-drug carriers with magnetic r...
A review on the synthesis of bio-based surfactants using green chemistry principles
A review on the synthesis of bio-based surfactants using green chemistry principles
With increasing awareness of the potential adverse impact of conventional surfactants on the environment and human health,...
Adverse drug reactions of Rituximab in patients suffering from autoimmune neurological diseases
Adverse drug reactions of Rituximab in patients suffering from autoimmune neurological diseases
Rituximab, a chimeric human/mouse monoclonal antibody targeting CD-20 antigens, has been used recently for various rheumat...
Effect of vitamins C and E on cancer survival; a systematic review
Effect of vitamins C and E on cancer survival; a systematic review
Association between vitamins C (VC)/ E (VE) and cancer survival is inconsistent. This systematic review is aimed to summar...
Dapsone improves the vincristine-induced neuropathic nociception by modulating neuroinflammation and oxidative stress
Dapsone improves the vincristine-induced neuropathic nociception by modulating neuroinflammation and oxidative stress
Peripheral neuropathy is a dose-limiting adverse effect of vincristine (VCR) in cancer chemotherapies. Dapsone is commonly...
Pharmacokinetic study of high-dose oral rifampicin in critically Ill patients with multidrug-resistant Acinetobacter baumannii infection
Pharmacokinetic study of high-dose oral rifampicin in critically Ill patients with multidrug-resistant Acinetobacter baumannii infection
Although rifampicin (RIF) is used as a synergistic agent for multidrug-resistant Acinetobacter baumannii (MDR-AB) infectio...
Novel biodegradable molecularly imprinted polymer nanoparticles for drug delivery of methotrexate anti-cancer; synthesis, characterization and cellular studies
Novel biodegradable molecularly imprinted polymer nanoparticles for drug delivery of methotrexate anti-cancer; synthesis, characterization and cellular studies
Recently biodegradable nanoparticles are the center of attention for the development of drug delivery systems. Molecularly...
A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines
A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines
Since the outbreak of the novel coronavirus disease 2019 (COVID-19) in Wuhan, China, many health care systems have been he...
Efficacy and safety of ibrutinib in mantle cell lymphoma: A systematic review and meta-analysis
Efficacy and safety of ibrutinib in mantle cell lymphoma: A systematic review and meta-analysis
Since the US Food and Drug Administration (FDA) approved ibrutinib to treat patients with refractory/relapsed mantle cell ...
Alpinumisoflavone against cancer pro-angiogenic targets: In silico, In vitro, and In ovo evaluation
Alpinumisoflavone against cancer pro-angiogenic targets: In silico, In vitro, and In ovo evaluation
Breast cancer is currently the world’s most predominant malignancy. In cancer progression, angiogenesis is a require...
Bioassay-Guided extraction of andrographis paniculata for intervention of in-vitro prostate cancer progression in metabolic syndrome environment
Bioassay-Guided extraction of andrographis paniculata for intervention of in-vitro prostate cancer progression in metabolic syndrome environment
Metabolic syndrome (MetS) is a risk factor for prostate cancer (PCa) progression. Thus, this life-threatening disease dema...
Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms
Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms
Scutellaria baicalensis (SB) has been traditionally used to combat a variety of conditions ranging from ischemic heart dis...
Wound healing and anti-inflammatory effects of bacterial cellulose coated with Pistacia atlantica fruit oil
Wound healing and anti-inflammatory effects of bacterial cellulose coated with Pistacia atlantica fruit oil
Biological activities of Pistacia atlantica have been investigated for few decades. The fruit oil of the plant ha...
Colistin induced acute kidney injury in critically ill children: a prospective study utilizing RIFLE criteria
Colistin induced acute kidney injury in critically ill children: a prospective study utilizing RIFLE criteria
Colistin is one of the last resort antibiotic options for resistant gram-negative pathogens. Renal injury is the most comm...
Successful treatment of acute-on-chronic liver failure secondary to alcoholic cirrhosis with glucocorticoids and albumin: a case report
Successful treatment of acute-on-chronic liver failure secondary to alcoholic cirrhosis with glucocorticoids and albumin: a case report
Glucocorticoids are used as a first-line treatment for severe alcoholic hepatitis, and albumin reduces both the number of ...
Design, synthesis and docking study of Vortioxetine derivatives as a SARS-CoV-2 main protease inhibitor
Design, synthesis and docking study of Vortioxetine derivatives as a SARS-CoV-2 main protease inhibitor
Vortioxetine an anti-depressant FDA-drug recently reported showing better in vitro efficacy against SARS-CoV-2. In this st...
West African medicinal plants and their constituent compounds as treatments for viral infections, including SARS-CoV-2/COVID-19
West African medicinal plants and their constituent compounds as treatments for viral infections, including SARS-CoV-2/COVID-19
The recent emergence of the COVID-19 pandemic (caused by SARS-CoV-2) and the experience of its unprecedented alarming toll...
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