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Comparative evaluation of different oral iron salts in the management of iron deficiency anemia
Comparative evaluation of different oral iron salts in the management of iron deficiency anemia
Anemia affects one-fourth of the world's population and is caused mostly by iron deficiency. Iron supplementation is t...
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)
Treatment management for opioid poisoning is critical and, at the same time, requires specialized knowledge and skills. Th...
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population
Cancer treatment has improved over the past decades, but many cancer patients still experience adverse drug reactions (ADR...
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
Rhinovirus (RV) infection is a major cause of common colds and asthma exacerbations, with no antiviral drug available. Cur...
Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system
Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system
Over the past decades, a substantial portion of the population worldwide has been infected with varicella zoster and most ...
Recent opportunities and application of gellan gum based drug delivery system for intranasal route
Recent opportunities and application of gellan gum based drug delivery system for intranasal route
In the recent years, in-situ hydrogel based on gellan gum has been investigated for delivery of various drug molecules par...
One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties
One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties
Amorphous hydrogel is a strategic wound healing dressings that comprised of water, polymers and excipients with no shape. ...
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats
5-Fluorouracil (5-FU) is an antimetabolite chemotherapeutic agent that can cause oxidative stress and complications in nor...
Active pharmaceutical contaminants in drinking water: myth or fact?
Active pharmaceutical contaminants in drinking water: myth or fact?
Global water availability has been affected by a variety of factors, including climate change, water pollution, urbanizati...
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development
Obesity has emerged as a major health challenge globally in the last two decades. Dysregulated fatty acid metabolism and d...
Lipid management strategies for diabetic patients align with an evidence-based guideline
Lipid management strategies for diabetic patients align with an evidence-based guideline
Diabetes mellitus (DM) increases the risk of cardiovascular diseases (CVD) significantly. Statins are recommended for all ...
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment
Glatiramer acetate (GA), a commonly used treatment for multiple sclerosis (MS), requires long-term frequent injections to ...
A review of the ethnomedicinal, phytochemical, and pharmacological properties of the Ferulago genus based on Structure–Activity Relationship (SAR) of coumarins
A review of the ethnomedicinal, phytochemical, and pharmacological properties of the Ferulago genus based on Structure–Activity Relationship (SAR) of coumarins
The Ferluago W.D.J. Koch genus includes 48 accepted perennial herbs that are distributed in the Mediterranean region, Sout...
Population Pharmacokinetics of Loxoprofen and its alcoholic metabolites in healthy Korean men
Population Pharmacokinetics of Loxoprofen and its alcoholic metabolites in healthy Korean men
Loxoprofen has been actively used clinically to relieve musculoskeletal pain and inflammatory symptoms. However, there are...
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater
Nilotinib (NIL) is a prescription medication employed in the treatment of specific types of leukemia, namely chronic myelo...
Hybrid derivatives containing dimethyl fumarate and benzothiazole scaffolds for the potential treatment of multiple sclerosis; in silico & in vivo study
Hybrid derivatives containing dimethyl fumarate and benzothiazole scaffolds for the potential treatment of multiple sclerosis; in silico & in vivo study
Multiple Sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease of the CNS. Riluzole and dimethyl fumar...
Plausible mechanism of drug resistance and side-effects of COVID-19 therapeutics: a bottleneck for its eradication
Plausible mechanism of drug resistance and side-effects of COVID-19 therapeutics: a bottleneck for its eradication
COVID-19 pandemic has turned our world upside down by meddling with our normal lives. While there is no definitive drug ag...
Evaluating the effect of sodium alginate and sodium carboxymethylcellulose on pulmonary delivery of levofloxacin spray-dried microparticles
Evaluating the effect of sodium alginate and sodium carboxymethylcellulose on pulmonary delivery of levofloxacin spray-dried microparticles
Patients with cystic fibrosis commonly suffer from lung infections caused by Pseudomonas aeruginosa. Recently, the Levoflo...
Preparation of poly(vinyl alcohol) nanofibers containing disulfiram-copper complex by electrospinning: a potential delivery system against melanoma
Preparation of poly(vinyl alcohol) nanofibers containing disulfiram-copper complex by electrospinning: a potential delivery system against melanoma
Melanoma poses a significant threat to human health, making the development of a safe and effective treatment a crucial ch...
Toxicological effect of acetaminophen, metamizole, and nimesulide cocktail on early development of zebrafish
Toxicological effect of acetaminophen, metamizole, and nimesulide cocktail on early development of zebrafish
Several countries’ most incorrectly discarded medicines are acetaminophen (ACM), metamizole (MTZ), and nimesulide (N...
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy
Sometimes clinical efficacy and potential risk of therapeutic and toxic agents are difficult to predict over a long period...
Repurposing metformin as a potential anticancer agent using in silico technique
Repurposing metformin as a potential anticancer agent using in silico technique
The focus on repurposing readily available, well-known drugs for new, creative uses has grown recently. One such medicatio...
Public interest in drug-related problems reflected in information search trends: an infodemiological study
Public interest in drug-related problems reflected in information search trends: an infodemiological study
The analysis of how people search and “navigate” the internet to obtain health-related information and how the...
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin
It has been reported that High-Fructose (HF) consumption, considered one of the etiological factors of Metabolic Syndrome ...
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies
The efficient delivery of drugs from dry powder inhaler (DPI) formulations is associated with the complex interaction betw...
Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report
Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report
A persistent difficult-to-treat cough can be exhausting. Iron is an essential element that plays an important role in regu...
Cost minimization analysis of subcutaneous trastuzumab versus intravenous biosimilar trastuzumab: policy recommendations for breast cancer treatment in Malaysia
Cost minimization analysis of subcutaneous trastuzumab versus intravenous biosimilar trastuzumab: policy recommendations for breast cancer treatment in Malaysia
Current clinical practice recommends switching innovator intravenous trastuzumab (IV-TZMi) to subcutaneous trastuzumab (SC...
Royal jelly and its hormonal effects in breast cancer: a literature review
Royal jelly and its hormonal effects in breast cancer: a literature review
Breast cancer is the most common cancer in women which can be cured in most individuals with early-stage non-metastatic di...
Targeting resistant breast cancer stem cells in a three-dimensional culture model with oleuropein encapsulated in methacrylated alginate microparticles
Targeting resistant breast cancer stem cells in a three-dimensional culture model with oleuropein encapsulated in methacrylated alginate microparticles
Cancer stem cells (CSCs) are a subpopulation of cancer cells that are believed to be responsible for tumor initiation, pro...
Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities
Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities
Aberrant expression of histone deacetylases (HDACs) and ribonucleotide reductase (RR) enzymes are commonly observed in var...
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