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Single-cell transcriptome sequencing partially revealed the changes of T cells in the early stage of aging kidney
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Inhibition of DNMT1 attenuates experimental food allergy
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Characteristics and functions of an atypical inflammation-associated GZMK+GZMB+CD8+ T subset in people living with HIV-1
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Inhibition of GBP1 alleviates pyroptosis of human pulmonary microvascular endothelial cells through STAT1/NLRP3/GSDMD pathway
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Escherichia coli LTB26 mutant enhances immune responses to rotavirus antigen VP8 in a mouse model
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Inhibiting caspase-3/GSDME-mediated pyroptosis ameliorates septic lung injury in mice model
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CD69+ Vδ1γδ T cells are anti-tumor subpopulations in hepatocellular carcinoma
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Single-cell transcriptomics reveals CD8+ T cell structure and developmental trajectories in idiopathic pulmonary fibrosis
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A monoclonal antibody that recognizes a unique 13-residue epitope in the cytoplasmic tail of HLA-E
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MiR-23b-3p alleviates Sjögren's syndrome by targeting SOX6 and inhibiting the NF-κB signaling
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Identification and evolution of PDK-1-like involving lamprey innate immunity
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Activation of Wnt/β-catenin signal induces DCs to differentiate into immune tolerant regDCs in septic mice
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Regulatory T cells as a therapeutic target in acute myocardial infarction
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Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration
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Serum amyloid P component: Structure, biological activity, and application in diagnosis and treatment of immune-associated diseases
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IL-17 in type II diabetes mellitus (T2DM) immunopathogenesis and complications; molecular approaches
IL-17 in type II diabetes mellitus (T2DM) immunopathogenesis and complications; molecular approaches
Type 2 diabetes mellitus (T2DM) is a chronic inflammatory disorder comprising 6.28% of the global population (Khan et al.,...
Integrative analysis of systemic lupus erythematosus biomarkers: Role of fecal hsa-mir-223–3p and gut microbiota in transkingdom dynamics
Integrative analysis of systemic lupus erythematosus biomarkers: Role of fecal hsa-mir-223–3p and gut microbiota in transkingdom dynamics
Systemic Lupus Erythematosus (SLE) is a chronic, autoimmune, multisystem inflammatory disease. Given its complex multifact...
Identification of HPV-E7 specific TCRs for tumor immunotherapy
Identification of HPV-E7 specific TCRs for tumor immunotherapy
Cervical cancer is the fourth most common malignancy in women, (Yue et al., 2023) with an estimated annual incidence of ap...
Complement decay-accelerating factor inhibits inflammation-induced myopia development
Complement decay-accelerating factor inhibits inflammation-induced myopia development
The complement system is an important defense mechanism in both innate and adaptive immunity, whose activation leads to cl...
The roles of B cells in cardiovascular diseases
The roles of B cells in cardiovascular diseases
Cardiovascular diseases are the number one cause of death globally, killing more people annually than any other cause, and...
IFN-α affects Th17/Treg cell balance through c-Maf and associated with the progression of EBV- SLE
IFN-α affects Th17/Treg cell balance through c-Maf and associated with the progression of EBV- SLE
ObjectivesSystemic lupus erythematosus (SLE) is a multi-organ autoimmune disease, of which the pathogens is remains obscur...
MXRA7 is involved in monocyte-to-macrophage differentiation
MXRA7 is involved in monocyte-to-macrophage differentiation
In a bioinformatics study in 2002 (Walker and Volkmuth, 2002), Walker and Volkmuth firstly identified eight genes that co-...
Grainyhead-like-2, an epithelial master programmer, promotes interferon induction and suppresses breast cancer recurrence
Grainyhead-like-2, an epithelial master programmer, promotes interferon induction and suppresses breast cancer recurrence
Type-I and -III interferons play a central role in immune rejection of pathogens and tumors, thus promoting immunogenicity...