SCI时时刷

search
+
Biologic choice matters in PsA prevention
In a large cohort of patients with psoriasis, treatment with biologic DMARDs targeting the IL-23 pathway was associated wi...
Hypothetical model ignores many important pathophysiologic mechanisms in fibromyalgia
Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, USADaniel J...
Reply to: Hypothetical model ignores many important pathophysiologic mechanisms in fibromyalgia
University of Coimbra, Center for Research in Neuropsychology and Cognitive and Behavioral Intervention (CINEICC), Faculty...
The potential contribution of in silico studies to improved treatment of osteoarthritis
The potential contribution of in silico studies to improved treatment of osteoarthritis
Osteoarthritis has many appearances and can stabilize or progress aggressively. However, there is not yet an aetiological ...
Imbalance of threat and soothing systems in fibromyalgia: rephrasing an established mechanistic model?
Pinto, A. M. et al. Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia. Nat. Re...
Reply to ‘Imbalance of threat and soothing systems in fibromyalgia: rephrasing an established mechanistic model?’
University of Coimbra, Center for Research in Neuropsychology and Cognitive and Behavioral Intervention (CINEICC), Faculty...
PPM1A: TGFβ regulator and therapeutic target in OA
Protein phosphatase magnesium-dependent 1A is a negative modulator of transforming growth factor β signalling and a p...
Co-trimoxazole reduces mortality in anti-MDA5-DM
Results indicate that prophylactic use of co-trimoxazole can reduce infection-related mortality in patients with new-onset...
Citrulline immunity in RA: CD8+ T cells enter the scene
Citrulline immunity in RA: CD8+ T cells enter the scene
The involvement of citrulline-specific CD4+ T cells in anti-citrulline protein antibody-positive rheumatoid arthritis (RA)...
Genetics and epigenetics of primary Sjögren syndrome: implications for future therapies
Genetics and epigenetics of primary Sjögren syndrome: implications for future therapies
In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue destruction and sicca sy...
Nanobody targets TNF and IL-6 for additive efficacy
Nanobody targets TNF and IL-6 for additive efficacy
A newly developed nanobody that simultaneously targets TNF and IL-6 has greater efficacy than individual targeting in rheu...
New biomarker panel best yet for prediction of OA progression
A panel of serum biomarkers identified by proteomic analysis outperforms the best current alternatives for prediction of t...
State-of-the-art evidence in the treatment of systemic sclerosis
State-of-the-art evidence in the treatment of systemic sclerosis
Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease with multi-organ involvement, fibrosis and vasculo...
Treatment of lupus nephritis: consensus, evidence and perspectives
Treatment of lupus nephritis: consensus, evidence and perspectives
Despite the continuing development of immunomodulatory agents and supportive care, the prognosis associated with lupus nep...
Diabetes increases risk of end-stage renal disease in SLE
Analyses of data from the Danish national patient register show that diabetes mellitus increases the risk of end-stage ren...
New immunoassay to screen for RA
Autoantibodies against rheumatoid arthritis (RA)-related peptides present in joints can be detected in the serum of patien...
PR3 triggers granuloma formation in GPA
A new study identifies proteinase 3 as an important driver of granuloma formation in granulomatosis with polyangiitis and ...
Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis
Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis
Sarcopenia, a disorder that involves the generalized loss of skeletal muscle strength and mass, was formally recognized as...
Pregnancy outcomes improving in axSpA
A cohort study of more than 1,500 births to women with axial spondyloarthritis reveals a trend of improvement in pregnancy...
Author Correction: Glycobiology of rheumatic diseases
In the version of this article initially published, there were presentation errors in the Figure 2 and 4 schematics, where...
The new look of classification criteria for systemic vasculitis
The new look of classification criteria for systemic vasculitis
An ambitious project to update the classification of vasculitis syndromes has culminated in the development of new classif...
Author Correction: Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management
Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USAZsuzsanna H. McMahanDivision of Gastroenterology, Be...
VEXAS syndrome more common than originally thought?
A new study provides an estimate of the prevalence of VEXAS syndrome based on the identification of pathogenic UBA1 varian...
Ageing matrix makes chondrocytes feel old
Age-related stiffening of the extracellular matrix in cartilage promotes chondrocyte ageing in an epigenetically controlle...
Piezo1 induces new bone formation in AS
Piezo1 induces new bone formation in AS
The mechanosensitive ion channel Piezo1 is involved in pathogenic new bone formation in entheseal tissues in ankylosing sp...
Iron uptake is a therapeutic target in SLE
Blockade of iron uptake by the transferrin receptor CD71 can reduce metabolic dysregulation in T cells, resulting in ameli...
A path towards personalized medicine for autoinflammatory and related diseases
A path towards personalized medicine for autoinflammatory and related diseases
The human genome project led to the advancement of genetic technologies and genomic medicine for a variety of human diseas...
Inflammation and DNA damage: cause, effect or both
Inflammation and DNA damage: cause, effect or both
Inflammation is a biological response involving immune cells, blood vessels and mediators induced by endogenous and exogen...
Bimekizumab effective across the axSpA spectrum
Bimekizumab effective across the axSpA spectrum
The IL-17A–IL-17F inhibitor bimekizumab is safe and effective for the treatment of both radiographic and non-radiogr...
Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management
Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management
Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the gastrointestinal tract, an...
阅读更多
format_indent_increase